Abstract: The instant invention provides an inositol 1,4,5-triphaosphate receptor (IP3R)-binding protein and its transgenic non-human mammalian animal. The inositol 1,4,5-triphaosphate receptor-binding protein comprises an inositol 1,4,5-triphaosphate receptor-binding protein with a protein including KRAP protein (SQ ID NOS. 1-4) bound to inositol 1,4,5-triphosphate (IP3R) protein (SQ ID NOS. 5-8). The IP3R activity inhibitor contains the IP3R-binding protein as a major ingredient. The transgenic non-human mammal of the instant invention carries the IP3R-binding protein. The site of binding of the KRAP protein to the IP3R protein is located in an amino acid region composed of 19 amino acids ranging from amino acid 200 to amino acid 218 of the mouse KRAP protein and an 19-amino acid region corresponding to that of the mouse KRAP protein for any animal species other than mouse.

Abstract: A double rate processing part generates, at a double rate, a non-interlaced image signal every frame to twice generate a double-rate non-interlaced signal which has identical information duplicately. An interlace part, after a predetermined process is carried out on the double-rate non-interlaced signal twice generated by the double rate processing part, extracts an odd scan lines from one of the twice generated double-rate non-interlaced signal to generate an odd scan line image signal, extracts an even scan lines from the other of the twice generated double-rate non-interlaced signal to generate an even scan line image signal, so as to obtain an interlaced image signal for one frame.

Abstract: An optical transceiver stores an output A/D value which is A/D-converted from reference voltage in an EEPROM as correction data in preparing the optical transceiver. The optical transceiver, receiving a request for outputting a monitored value from an external device connected therewith, calculates a variation based on difference between the output A/D value which is A/D-converted from the reference voltage at the timing when the request for outputting the monitored value is received and the correction data stored in the EEPROM. Then, the optical transceiver uses the calculated variation to convert current of light-input power which is input thereinto into voltage, amplify the voltage, and A/D-convert the voltage to thereby correct the output A/D value. The optical transceiver outputs the corrected A/D value to the connected external device as the monitored value.

Abstract: The inhibitory RNA for inhibiting the expression of ZFAT gene according to this invention is a siRNA comprising a sense RNA having a base sequence of contiguous 20 to 20 bases, preferably 23 to 27 bases, of ZFAT mRNA and an anti-sense RNA having a base sequence complementary to the base sequence of the sense RNA or a shRNA comprising a double-stranded RNA (dsRNA) with the sense RNA connected to the anti-sense RNA via a loop sequence. The inhibitory RNA for inhibiting the expression of ZFAT gene according to this invention decreases a rate of cell proliferation of cancer cells, etc., induces apoptosis of cells including cancer cells, or inhibits an immunoresponse by inhibiting the expression of the ZFAT gene. Therefore, the inhibitory RNA of this invention is useful for development of molecular target agents particularly for cancer cells or immunosuppressive agents.

Abstract: A brake disc for a railway vehicle, including a ring-shaped plate portion with a front side serving as a frictional surface and a plurality of fins being projected and disposed radially on the back side of the plate portion, the plate portion being fixed to a wheel, wherein a rib is provided between fins adjacent to each other, and a slit developing in the direction from a wheel-side face of the rib toward the back side of the plate portion is disposed in a circumferentially intermediate portion of the rib, thereby making it possible to suppress the deformation caused by frictional heat.

Abstract: A phase modulated signal receiver includes an operation part and a control part. An input power of a received light signal is measured based on current monitored by a monitor circuit. The operation part is configured to correct, on the basis of a ratio of the input power measured when a delay of a phase reference light output from a delay interferometer is a first delay and the input power when the delay of the phase reference light is a second delay, a value of the current monitored by the monitor circuit when the delay is the first delay to a corrected value that depends on the input power of the received light signal obtained when the delay is the first delay. The control part is configured to control the delay of the phase reference light of the delay interferometer by comparing the current monitored when the delay is the first delay and the corrected value of the current monitored when the delay is the second delay and maximizing or minimizing the current monitored by the monitor circuit.

Abstract: An optical receiving apparatus, including an optical interferometer including first and second optical waveguides having light paths different in length and converting a phase modulated signal received by the optical receiving apparatus into an intensity modulated signal, monitors the results of the detecting by the temperature detector and the measuring by the electric current measure while sweeping the temperature of the first optical waveguide in a predetermined range; selects the temperature of the first optical waveguide at which temperature the average photocurrent has an extreme value based on the result of the monitoring; and varies the temperature of the first optical waveguide to the selected temperature.

Abstract: The object is to provide an etching liquid for a conductive polymer having excellent etching capability toward a conductive polymer, and a method for patterning a conductive polymer employing the etching liquid for a conductive polymer. The conductive etching liquid of the present invention is selected from the group consisting of (1) an etching liquid comprising greater than 0.5 wt % but no greater than 70 wt % of (NH4)2Ce(NO3)8 or at least 0.5 wt % but no greater than 30 wt % of Ce(SO4)2, (2) an etching liquid comprising greater than 0.5 wt % but no greater than 30 wt % of (NH4)4Ce(SO4)4, (3) an etching liquid comprising a hypochlorous acid salt aqueous solution having an effective chlorine concentration of at least 0.06 wt % and a pH of greater than 3 but less than 8, (4) an etching liquid comprising nitrosyl chloride which comprises at least 5 wt % of hydrochloric acid and at least 20 wt % of nitric acid, a (hydrochloric acid concentration+0.

Abstract: An optical transceiver stores an output A/D value which is A/D-converted from reference voltage in an EEPROM as correction data in preparing the optical transceiver. The optical transceiver, receiving a request for outputting a monitored value from an external device connected therewith, calculates a variation based on difference between the output A/D value which is A/D-converted from the reference voltage at the timing when the request for outputting the monitored value is received and the correction data stored in the EEPROM. Then, the optical transceiver uses the calculated variation to convert current of light-input power which is input thereinto into voltage, amplify the voltage, and A/D-convert the voltage to thereby correct the output A/D value. The optical transceiver outputs the corrected A/D value to the connected external device as the monitored value.

Abstract: A double rate processing part generates, at a double rate, a non-interlaced image signal every frame to twice generate a double-rate non-interlaced signal which has identical information duplicately. An interlace part, after a predetermined process is carried out on the double-rate non-interlaced signal twice generated by the double rate processing part, extracts an odd scan lines from one of the twice generated double-rate non-interlaced signal to generate an odd scan line image signal, extracts an even scan lines from the other of the twice generated double-rate non-interlaced signal to generate an even scan line image signal, so as to obtain an interlaced image signal for one frame.

Abstract: An optical transmitter includes a laser diode drive circuit for driving a laser diode in accordance with a laser diode current that superimposes a pilot signal on a “0” logic level and a “1” logic level of a transmission signal, the pilot signal having a low-frequency compared with the transmission signal, so as to become an opposite phase each other, a monitor circuit for monitoring an optical output of the laser diode, a filter circuit for extracting a low-frequency component of the pilot signal from an output of the monitor circuit, a phase compare circuit for comparing a phase of the low-frequency component of the pilot signal extracted by the filter circuit with a phase of the pilot signal, and a deterioration judgment circuit for judging whether or not the laser diode deteriorates in accordance with a comparison result of the phase compare circuit.

Abstract: An apparatus for controlling an extinction ratio of a light-emitting device, includes: a temperature detecting unit that detects a temperature of the device; a power detecting unit that detects an optical output power of the device; a modulation-current detecting unit that detects a modulation current input into the device; a POW computing unit that computes a power control value for the device based on the temperature; and an ER computing unit that computes an extinction ratio control value for the device based on the power control value, the optical output power, and the modulation current.

Abstract: Glycidyl methacrylate is produced by the reaction of an alkali metal salt of methacrylic acid with epichlorohydrin in the presence of a quaternary ammonium salt and a polymerization inhibitor in a reaction system where the water content is adjusted to 500 to 2000 ppm. Glycidyl methacrylate is purified by the method of the present invention, wherein the reaction mixture obtained by the above method is washed with a dilute aqueous solution of sodium hydroxide and heated under a reduced pressure to remove unchanged epichlorohydrin by distillation, after which steam is blown into the reaction system under the conditions of reduced pressure and heating to distill away the remaining epichlorohydrin together with glycidyl methacrylate as the first distillate fraction, followed by ceasing the steam blow and carrying out distillation under the conditions of reduced pressure and heating to obtain glycidyl methacrylate as the main distillate fraction.

Abstract: An apparatus for detecting a defect in an insulator formed therein with an axially extending hollow section; having a hold section 2 for holding the insulator, a first electrode 3 inserted in the hollow section 1a of the insulator 1, and a second electrode provided outside of the insulator 1. An electric discharge structure 10 produces an electric discharge between the first and second electrodes 3, 5, a path recognizes 11, 12, 13 for recognizes whether the electric discharge passes through a predetermined path, and a discriminating structure 14 for discriminates whether the insulator 1 is satisfactory, in accordance with a signal from the path recognizes.