Patents by Inventor Takahiro HIOKI

Takahiro HIOKI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240043822
    Abstract: Provided are a polypeptide having a glycine-glycine bond-degrading activity and an improved microbicidal activity, and a method for using the same.
    Type: Application
    Filed: October 6, 2021
    Publication date: February 8, 2024
    Applicant: KAO CORPORATION
    Inventors: Takahiro HIOKI, Daichi YAMASHITA, Akihito KAWAHARA
  • Patent number: 11891590
    Abstract: Provided is a detergent having a high detergency against corneum-derived stains and a method for evaluating the ability of an enzyme to degrade corneum-derived stains. The detergent a M23A subfamily protease as an active ingredient. The method for evaluating the ability of the enzyme to degrade corneum-derived stains comprises obtaining the degrading activities of the test enzyme on a reference peptide and one or more substrate peptides and evaluating the ability of the test enzyme to degrade corneum-derived stains based on the degrading activities of the test enzyme on the reference peptide and the substrate peptide, wherein the reference peptide is GGGGG or GGGG, the one or more substrate peptides are selected from the group consisting of GGGXG, GXGGG, GGXG, and GXGG, and X is any amino acid residue other than glycine.
    Type: Grant
    Filed: January 15, 2019
    Date of Patent: February 6, 2024
    Assignee: Kao Corporation
    Inventors: Daichi Yamashita, Takahiro Hioki, Masatoshi Tohata
  • Publication number: 20230313164
    Abstract: Provided is an ?-amylase which can function at low temperatures while maintaining or enhancing stability and/or cleaning performance. An ?-amylase mutant, which is a mutant of a parent ?-amylase, the ?-amylase mutant comprising one or more modifications to amino acid residues at positions corresponding to positions G5, S38, T49, Q96, N126, T129, G140, F153, Q167, G179, W186, E187, N192, M199, Y200, L203, Y205, D206, R211, K215, H240, S241, Y242, G244, E257, F259, K278, H283, S284, A288, H295, Y296, N303, T320, S331, L348, Y360, W408, L429, V430, G433, A434, W439, N471, G476, and G477 in the amino acid sequence of SEQ ID NO: 2, the parent ?-amylase or ?-amylase mutant having at least 90% sequence identity to the amino acid sequence of SEQ ID NO: 4.
    Type: Application
    Filed: September 29, 2021
    Publication date: October 5, 2023
    Applicant: KAO CORPORATION
    Inventors: Takahiro HIOKI, Mao SHAKU, Akihito KAWAHARA
  • Publication number: 20230272309
    Abstract: Provided is a cleaning composition containing ?-amylase which exhibits high specific activity at low temperatures. The cleaning composition comprises one or more proteins selected from the group consisting of the following (A), (B), (C), and (D): (A) a protein consisting of an amino acid sequence having at least 90% identity to the amino acid sequence of SEQ ID NO: 2, and having ?-amylase activity; (B) a protein consisting of an amino acid sequence having at least 90% identity to the amino acid sequence of SEQ ID NO: 4, and having ?-amylase activity; (C) a protein consisting of an amino acid sequence having at least 90% identity to the amino acid sequence of SEQ ID NO: 6, and having ?-amylase activity; and (D) a protein consisting of an amino acid sequence having at least 90% identity to the amino acid sequence of SEQ ID NO: 8, and having ?-amylase activity.
    Type: Application
    Filed: July 7, 2021
    Publication date: August 31, 2023
    Applicant: KAO CORPORATION
    Inventors: Takahiro HIOKI, Akihito KAWAHARA
  • Patent number: 11371034
    Abstract: Provided is a method for efficiently producing an M23A family protease. The method for producing an M23A family protease includes culturing bacteria of the genus Bacillus having a polynucleotide encoding a proprotein of the M23A family protease introduced thereinto to produce a mature form of the M23A family protease extracellularly from the bacteria of the genus Bacillus.
    Type: Grant
    Filed: January 15, 2019
    Date of Patent: June 28, 2022
    Assignee: Kao Corporation
    Inventors: Takahiro Hioki, Daichi Yamashita, Masatoshi Tohata
  • Publication number: 20210207116
    Abstract: Provided is a method for efficiently producing an M23A family protease. The method for producing an M23A family protease includes culturing bacteria of the genus Bacillus having a polynucleotide encoding a proprotein of the M23A family protease introduced thereinto to produce a mature form of the M23A family protease extracellularly from the bacteria of the genus Bacillus.
    Type: Application
    Filed: January 15, 2019
    Publication date: July 8, 2021
    Applicant: Kao Corporation
    Inventors: Takahiro HIOKI, Daichi YAMASHITA, Masatoshi TOHATA
  • Publication number: 20210071114
    Abstract: The present invention provides a detergent having a high detergency against corneum-derived stains, a method for evaluating the ability of an enzyme or a composition comprising the enzyme to degrade corneum-derived stains. A detergent comprising an M23A subfamily protease as an active ingredient.
    Type: Application
    Filed: January 15, 2019
    Publication date: March 11, 2021
    Applicant: Kao Corporation
    Inventors: Daichi YAMASHITA, Takahiro HIOKI, Masatoshi TOHATA