Patents by Inventor Takahiro MURAOKA

Takahiro MURAOKA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SELF-ASSEMBLING PEPTIDE
    Publication number: 20230203116
    Abstract: An object is to provide a peptide gelling agent which gels under physiological conditions and which has a relatively short chain length, and a sustained-release gel based on it. Provided is a hydrogelling self-assembling peptide comprising one or two core peptides consisting of an amino acid sequence represented by the following formula: Xaa-Yaa-Zaa-Yaa-Xaa-Yaa-Zaa-Yaa-Xaa, wherein Xaa is independently Ile or Met, Yaa is independently Asp, Glu, Lys, or Arg, and Zaa is independently Ala or Gly, and wherein the full length of the amino acid sequence constituting said self-assembling peptide is 25 amino acids or less.
    Type: Application
    Filed: July 29, 2021
    Publication date: June 29, 2023
    Applicants: NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY, KANAGAWA INSTITUTE OF INDUSTRIAL SCIENCE AND TECHNOLOGY
    Inventors: Takahiro MURAOKA, Atsuya YAGUCHI, Itsuki AJIOKA, Go WATANABE
  • Hetero type monodispersed polyethylene glycol, intermediate for production of hetero type monodispersed polyethylene glycol, methods for producing same, and hetero type monodispersed polyethylene glycol conjugate
    Patent number: 10435509
    Abstract: A hetero type monodispersed polyethylene glycol containing a compound represented by the following formula (1): NH2—(CH2CH2O)a—CH2CH2COOH??(1) (in the formula (1), a represents an integer from 6 to 40); wherein any of (A) a chromatogram detected by a differential refractometer when the hetero type monodispersed polyethylene glycol is separated using reverse phase chromatography, (B) a chromatogram detected by a differential refractometer when the hetero type monodispersed polyethylene glycol is separated using cation exchange chromatography, and (C) a chromatogram detected by a differential refractometer when the hetero type monodispersed polyethylene glycol containing a compound represented by the formula (1) shown above is derivatized and separated using anion exchange chromatography satisfy specific relational expressions, respectively.
    Type: Grant
    Filed: June 29, 2016
    Date of Patent: October 8, 2019
    Assignees: TOHOKU TECHNO ARCH CO., LTD., NOF CORPORATION
    Inventors: Kazushi Kinbara, Takahiro Muraoka, Adam Marcin Wawro, Tomoyuki Ohtake, Eui-chul Kang, Tomoki Uruga, Ryutaro Imamura
  • HETERO TYPE MONODISPERSED POLYETHYLENE GLYCOL, INTERMEDIATE FOR PRODUCTION OF HETERO TYPE MONODISPERSED POLYETHYLENE GLYCOL, METHODS FOR PRODUCING SAME, AND HETERO TYPE MONODISPERSED POLYETHYLENE GLYCOL CONJUGATE
    Publication number: 20180186931
    Abstract: A hetero type monodispersed polyethylene glycol containing a compound represented by the following formula (1): NH2—(CH2CH2O)a—CH2CH2COOH??(1) (in the formula (1), a represents an integer from 6 to 40); wherein any of (A) a chromatogram detected by a differential refractometer when the hetero type monodispersed polyethylene glycol is separated using reverse phase chromatography, (B) a chromatogram detected by a differential refractometer when the hetero type monodispersed polyethylene glycol is separated using cation exchange chromatography, and (C) a chromatogram detected by a differential refractometer when the hetero type monodispersed polyethylene glycol containing a compound represented by the formula (1) shown above is derivatized and separated using anion exchange chromatography satisfy specific relational expressions, respectively.
    Type: Application
    Filed: June 29, 2016
    Publication date: July 5, 2018
    Applicants: TOHOKU TECHNO ARCH CO., LTD., NOF CORPORATION
    Inventors: Kazushi KINBARA, Takahiro MURAOKA, Marcin Adam WAWRO, Tomoyuki OHTAKE, Eui-chul KANG, Tomoki URUGA, Ryutaro IMAMURA