Patents by Inventor Takahiro Nakajima

Takahiro Nakajima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10378011
    Abstract: An oligonucleotide having improved affinity for AGO2 is disclosed. The oligonucleotide has a nucleotide residue or a nucleoside residue represented by formula (I) wherein X1 is an oxygen atom or the like, R1 is formula (IIA), wherein R5A is halogen or the like, and R6A is a hydrogen atom or the like, or formula (IVA) wherein Y3A is a nitrogen atom or the like, and Y4A is CH or the like, or the like, R2 is a hydrogen atom, hydroxy, halogen, or optionally substituted lower alkoxy, and R3 is a hydrogen atom or the like at the 5? end thereof, and the nucleotide residue or the nucleoside residue binds to an adjacent nucleotide residue through the oxygen atom at position 3. A method for improving the knockdown activity of an oligonucleotide wherein the oligonucleotide has a knockdown activity against an mRNA encoding a protein involved in a disease.
    Type: Grant
    Filed: September 2, 2013
    Date of Patent: August 13, 2019
    Assignee: KYOWA HAKKO KIRIN CO., LTD.
    Inventors: Fumikazu Shinohara, Asana Makino, Junichiro Yamamoto, Taiji Oashi, Michihiko Suzuki, Jun-ichi Saito, Takahiro Nakajima, Tomoyuki Nishikawa, Masayoshi Nakoji, Yuichi Takahashi
  • Patent number: 10361378
    Abstract: Provided is a practically useful organic EL element having high efficiency and high driving stability while being capable of being driven at a low voltage. The organic EL element has a light-emitting layer and any other organic layer between an anode and a cathode opposite to each other. The light-emitting layer contains at least two host materials and at least one light-emitting dopant. At least one of the host materials is a host material selected from compounds each having one or two indolocarbazole skeletons, and at least one of the other host materials is a host material selected from carbazole compounds each substituted with a dibenzofuran or a dibenzothiophene.
    Type: Grant
    Filed: November 21, 2013
    Date of Patent: July 23, 2019
    Assignees: NIPPON STEEL CHEMICAL & MATERIAL CO., LTD., PIONEER CORPORATION, TOHOKU PIONEER CORPORATION
    Inventors: Masashi Tada, Takahiro Kai, Katsuhide Noguchi, Yasuhiro Takahashi, Yuhki Terao, Taishi Tsuji, Yusuke Nakajima, Toshinao Yuki
  • Patent number: 10342819
    Abstract: An oligonucleotide having a nucleotide residue or a nucleoside residue represented by formula (I) {wherein X1 is an oxygen atom or the like, R1 is formula (IIA) (wherein R5A is halogen or the like, and R6A is a hydrogen atom or the like), formula (IVA) (wherein Y3A is a nitrogen atom or the like, and Y4A is CH or the like), or the like, R2 is a hydrogen atom, hydroxy, halogen, or optionally substituted lower alkoxy, and R3 is a hydrogen atom or the like, or formula (VI) (wherein n2 is 1, 2 or 3)} at the 5? end thereof, wherein the nucleotide residue or the nucleoside residue binds to an adjacent nucleotide residue through the oxygen atom at position 3, is provided.
    Type: Grant
    Filed: March 3, 2015
    Date of Patent: July 9, 2019
    Assignee: KYOWA HAKKO KIRIN CO., LTD.
    Inventors: Fumikazu Shinohara, Asana Makino, Junichiro Yamamoto, Takahiro Nakajima, Taiji Oashi, Michihiko Suzuki, Jun-ichi Saito, Tomoyuki Nishikawa, Masayoshi Nakoji, Yuichi Takahashi, Yasuo Kouda
  • Patent number: 10340460
    Abstract: Provided is a practically useful organic electroluminescent device (organic EL device) having high efficiency and high driving stability while being capable of being driven at a low voltage. The organic electroluminescent device includes a light-emitting layer between an anode and a cathode opposite to each other. The light-emitting layer contains two host materials and at least one light-emitting dopant. One of the two host materials is a host material selected from an indolocarbazole compound having one indolocarbazole ring and an indolocarbazole compound having two indolocarbazole rings, and the other thereof is a host material selected from carbazole compounds.
    Type: Grant
    Filed: March 25, 2013
    Date of Patent: July 2, 2019
    Assignees: NIPPON STEEL CHEMICAL & MATERIAL CO., LTD., PIONEER CORPORATION, TOHOKU PIONEER CORPORATION
    Inventors: Takayuki Fukumatsu, Katsuhide Noguchi, Masashi Tada, Mitsuru Sakai, Tohru Asari, Kazuto Shiraishi, Takahiro Kai, Yasuhiro Takahashi, Yuhki Terao, Taishi Tsuji, Yusuke Nakajima, Toshinao Yuki
  • Publication number: 20190193397
    Abstract: A liquid ejecting head includes a plurality of driving elements that causes an ejection of a liquid from a nozzle by causing a fluctuation in a pressure, a sealing body that seals a first space for accommodating the plurality of driving elements, a case member that forms a second space for surrounding the sealing body, an atmosphere vent that is formed in the case member and through which the second space communicates with the air, a communication hole that is formed in the sealing body and through which the first space communicates with the second space, and a moisture absorbent disposed in the second space.
    Type: Application
    Filed: December 27, 2018
    Publication date: June 27, 2019
    Inventors: Yoshinori NAKAJIMA, Takahiro KANEGAE, Hiroshige OWAKI, Makoto OTSUKI, Hironori MATSUOKA
  • Patent number: 10317049
    Abstract: A light irradiation device includes a plurality of light-emitting portions that emit light by being supplied with a current. The light-emitting portions each have a first power supply terminal, and a second power supply terminal; a plurality of light-emitting elements; and a wiring pattern. The wiring pattern has a first wiring region and a second wiring region. Two of the light-emitting portions that are disposed adjacent to each other are disposed such that the space between the respective first wiring regions or the space between the respective second wiring regions is smaller than the space between the first wiring region of one of the light-emitting portions and the second wiring region of the other of the light-emitting portions.
    Type: Grant
    Filed: November 2, 2016
    Date of Patent: June 11, 2019
    Assignee: USHIO DENKI KABUSHIKI KAISHA
    Inventors: Takahiro Inoue, Takeo Matsushima, Toshihiro Nakajima, Junichi Kinoshita, Kenji Ishida
  • Patent number: 10239884
    Abstract: There is provided a series of coelenterazine (CTZ) derivatives as a substrate with high luminescence intensity, which is optimal for maximum luminescence wavelengths at both 400 nm (blue-shifted RLuc luminescence system) and 500 nm (ALuc luminescence system) for bioassays which is more sensitive than known techniques. The novel CTZ derivatives are compounds in which a specific position(s) of the CTZ is/are substituted with a specific substituent(s) as shown, for example, by the Formula [I], and has a higher luminescence intensity than known CTZ derivatives in blue-shifted RLuc luminescence system or ALuc luminescence system.
    Type: Grant
    Filed: March 20, 2018
    Date of Patent: March 26, 2019
    Assignees: KEIO UNIVERSITY, NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY, THE UNIVERSITY OF TOKYO
    Inventors: Koji Suzuki, Daniel Citterio, Ryo Nishihara, Sung-Bae Kim, Moritoshi Sato, Takahiro Nakajima
  • Publication number: 20190033748
    Abstract: A toner cartridge for use with an image forming apparatus includes a memory storing identification data of the toner cartridge and parameter information including image formation process parameters dependent on toner characteristic or ambient conditions. A transceiver unit communicates with the image forming apparatus to send the process parameter information stored in the memory to the image forming apparatus when the identification data is authentic.
    Type: Application
    Filed: September 28, 2018
    Publication date: January 31, 2019
    Inventors: Toru HOMMA, Hiroshi Hashidume, Hisanobu Ajima, Nobuo Tohata, Takahiro Nakajima, Takumi Hatano
  • Publication number: 20190010136
    Abstract: The present invention provides an ?,?-unsaturated amide compound or a pharmaceutically acceptable salt or the like thereof having anticancer activity and the like represented by the following formula (I): [wherein, “A” represents optionally substituted heterocyclic diyl, R1 represents hydrogen atom or optionally substituted lower alkyl, R2 represents optionally substituted aryl, optionally substituted cycloalkyl, optionally substituted aliphatic heterocyclic group or optionally substituted aromatic heterocyclic group, X represents —O—, —S—, —SO2—, —NRX1— (wherein, RX1 represents hydrogen atom or lower alkyl), —CHRX2— (wherein, RX2 represents hydrogen atom or hydroxy), —CH?CH—, —CO— or —NH—CO—, and n1 and n2 are the same or different, and each represents 0 or 1].
    Type: Application
    Filed: December 22, 2016
    Publication date: January 10, 2019
    Applicant: KYOWA HAKKO KIRIN CO., LTD.
    Inventors: Tomohiro DANJO, Katsuaki FUJIWARA, Tomoyuki NISHIKAWA, Takahiro NAKAJIMA, Nobumasa OTSUBO, Toshihiro SEIKE
  • Patent number: 10175606
    Abstract: A toner cartridge for use with an image forming apparatus includes a memory storing identification data of the toner cartridge and parameter information including image formation process parameters dependent on toner characteristic or ambient conditions. A transceiver unit communicates with the image forming apparatus to send the process parameter information stored in the memory to the image forming apparatus when the identification data is authentic.
    Type: Grant
    Filed: March 6, 2018
    Date of Patent: January 8, 2019
    Assignees: TOSHIBA TEC KABUSHIKI KAISHA, TOSHIBA AMERICA BUSINESS SOLUTIONS, INC.
    Inventors: Toru Homma, Hiroshi Hashidume, Hisanobu Ajima, Nobuo Tohata, Takahiro Nakajima, Takumi Hatano
  • Publication number: 20190004507
    Abstract: An association relationship between monitoring-object by a monitoring-apparatus and maintenance-object by a maintenance-management-apparatus is difficult to understand.
    Type: Application
    Filed: September 4, 2018
    Publication date: January 3, 2019
    Inventors: Takeshi DAITOU, Takahiro NAKAJIMA
  • Publication number: 20180273539
    Abstract: There is provided a series of coelenterazine (CTZ) derivatives as a substrate with high luminescence intensity, which is optimal for maximum luminescence wavelengths at both 400 nm (blue-shifted RLuc luminescence system) and 500 nm (ALuc luminescence system) for bioassays which is more sensitive than known techniques. The novel CTZ derivatives are compounds in which a specific position(s) of the CTZ is/are substituted with a specific substituent(s) as shown, for example, by the Formula [I], and has a higher luminescence intensity than known CTZ derivatives in blue-shifted RLuc luminescence system or ALuc luminescence system.
    Type: Application
    Filed: March 20, 2018
    Publication date: September 27, 2018
    Applicants: KEIO UNIVERSITY, NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY, The University of Tokyo
    Inventors: Koji SUZUKI, Daniel CITTERIO, Ryo NISHIHARA, Sung-Bae KIM, Moritoshi SATO, Takahiro NAKAJIMA
  • Publication number: 20180196371
    Abstract: A toner cartridge for use with an image forming apparatus includes a memory storing identification data of the toner cartridge and parameter information including image formation process parameters dependent on toner characteristic or ambient conditions. A transceiver unit communicates with the image forming apparatus to send the process parameter information stored in the memory to the image forming apparatus when the identification data is authentic.
    Type: Application
    Filed: March 6, 2018
    Publication date: July 12, 2018
    Inventors: Toru HOMMA, Hiroshi HASHIDUME, Hisanobu AJIMA, Nobuo TOHATA, Takahiro NAKAJIMA, Takumi HATANO
  • Patent number: 9927736
    Abstract: A toner cartridge for use with an image forming apparatus includes a memory storing identification data of the toner cartridge and parameter information including image formation process parameters dependent on toner characteristic or ambient conditions. A transceiver unit communicates with the image forming apparatus to send the process parameter information stored in the memory to the image forming apparatus when the identification data is authentic.
    Type: Grant
    Filed: June 5, 2017
    Date of Patent: March 27, 2018
    Assignees: Toshiba TEC Kabushiki Kaisha, Toshiba American Business Solutions, Inc.
    Inventors: Toru Homma, Hiroshi Hashidume, Hisanobu Ajima, Nobuo Tohata, Takahiro Nakajima, Takumi Hatano
  • Patent number: 9875295
    Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for evaluating substitute terms. One of the methods includes receiving a query having an original term and determining one or more substitution contexts for the original term, wherein a substitution context includes one or more context terms and an indication of a position in the query of the original term and the one or more context terms. The substitution contexts are classified into a first category or a second category based on a respective score of each substitution context. The original term is associated with one or more substitution contexts in the first category.
    Type: Grant
    Filed: October 11, 2016
    Date of Patent: January 23, 2018
    Assignee: Goolge Inc.
    Inventors: Zachary A. Garrett, Takahiro Nakajima, Akira Ishino, Kenichi Kurihara
  • Publication number: 20170354673
    Abstract: An oligonucleotide having a nucleotide residue or a nucleoside residue represented by formula (I) {wherein X1 is an oxygen atom or the like, R1 is formula (IIA) (wherein R5A is halogen or the like, and R6A is a hydrogen atom or the like), formula (IVA) (wherein Y3A is a nitrogen atom or the like, and Y4A is CH or the like), or the like, R2 is a hydrogen atom, hydroxy, halogen, or optionally substituted lower alkoxy, and R3 is a hydrogen atom or the like, or formula (VI) (wherein n2 is 1, 2 or 3)} at the 5? end thereof, wherein the nucleotide residue or the nucleoside residue binds to an adjacent nucleotide residue through the oxygen atom at position 3, is provided.
    Type: Application
    Filed: March 3, 2015
    Publication date: December 14, 2017
    Applicant: Kyowa Hakko Kirin Co., Ltd.
    Inventors: Fumikazu SHINOHARA, Asana MAKINO, Junichiro YAMAMOTO, Takahiro NAKAJIMA, Taiji OASHI, Michihiko SUZUKI, Jun-ichi SAITO, Tomoyuki NISHIKAWA, Masayoshi NAKOJI, Yuichi TAKAHASHI, Yasuo KOUDA
  • Publication number: 20170269503
    Abstract: A toner cartridge for use with an image forming apparatus includes a memory storing identification data of the toner cartridge and parameter information including image formation process parameters dependent on toner characteristic or ambient conditions. A transceiver unit communicates with the image forming apparatus to send the process parameter information stored in the memory to the image forming apparatus when the identification data is authentic.
    Type: Application
    Filed: June 5, 2017
    Publication date: September 21, 2017
    Inventors: Toru HOMMA, Hiroshi HASHIDUME, Hisanobu AJIMA, Nobuo TOHATA, Takahiro NAKAJIMA, Takumi HATANO
  • Patent number: 9690230
    Abstract: A toner cartridge for use with an image forming apparatus includes a memory storing identification data of the toner cartridge and parameter information including image formation process parameters dependent on toner characteristic or ambient conditions. A transceiver unit communicates with the image forming apparatus to send the process parameter information stored in the memory to the image forming apparatus when the identification data is authentic.
    Type: Grant
    Filed: January 21, 2016
    Date of Patent: June 27, 2017
    Assignees: Toshiba TEC Kabushiki Kaisha, Toshiba America Business Solutions, Inc.
    Inventors: Toru Homma, Hiroshi Hashidume, Hisanobu Ajima, Nobuo Tohata, Takahiro Nakajima, Takumi Hatano
  • Patent number: 9540366
    Abstract: The ring-fused heterocyclic compound or a pharmaceutically acceptable salt thereof according to the present invention has a T-type calcium channel regulatory effect, and is useful, for example, as a medicament for treating and/or preventing pruritus. The present invention provides a ring-fused heterocyclic compound represented by the following general formula (I) or a pharmaceutically acceptable salt thereof and the like which has a T-type calcium channel regulatory effect and is useful as a therapeutic and/or preventive agent for pruritus, and the like.
    Type: Grant
    Filed: July 31, 2013
    Date of Patent: January 10, 2017
    Assignee: Kyowa Hakko Kirin Co., Ltd.
    Inventors: Takayuki Furuta, Takashi Sawada, Tomohiro Danjo, Takahiro Nakajima, Noriaki Uesaka
  • Patent number: 9514223
    Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for training recognition canonical representations corresponding to named-entity phrases in a second natural language based on translating a set of allowable expressions with canonical representations from a first natural language, which may be generated by expanding a context-free grammar for the allowable expressions for the first natural language.
    Type: Grant
    Filed: October 26, 2015
    Date of Patent: December 6, 2016
    Assignee: Google Inc.
    Inventors: Zachary A. Garrett, Takahiro Nakajima, Tasuku Oonishi