Abstract: The present invention provides an antibacterial composition capable of forming an antibacterial film having suppressed coloration, excellent antibacterial property, and suppressed film cracking, antibacterial film, and an antibacterial film-attached substrate. The antibacterial composition of the present invention includes a silver-based antibacterial agent containing zirconium phosphate and silver carried and supported on the zirconium phosphate, a monomer having a polymerizable group, and a solvent. The monomer having a polymerizable group includes a first monomer having a polymerizable group and a hydrophilic group, and a second monomer having a polymerizable group and having no hydrophilic group, and the content of the first monomer is 30% to 70% by mass with respect to the total mass of the monomer having a polymerizable group.

Abstract: An object of the present invention is to provide an antibacterial film having an antiglare function and excellent image visibility, a touch panel, and a manufacturing method for an antibacterial film. An antibacterial film of the present invention contains a base material and at least one antibacterial layer disposed on the base material, in which the antibacterial layer contains a binder, a light diffusing particle, and an antibacterial agent particle and satisfies a specific condition 1.

Abstract: Provided herein are methods and compositions for long term treatment of spinal pain. In particular, use of double-stranded oligonucleotide decoys capable of binding to the DNA binding sites of two transcription factors are provided for treatment of spinal pain for over seven days, where the decoys are administered without a drug delivery system.

Abstract: Disclosed is a double-stranded oligonucleotide decoy including two transcription factor-binding sites, while keeping its size small. The double-stranded oligonucleotide decoy showing binding affinities for two transcription factors includes a first binding site for a first transcription factor and a second binding site for a second transcription factor. A first strand including the sense strand of the first binding site and a second strand including the sense strand of the second binding site are hybridized to form a double strand in which the sense strand of the first binding site and the sense strand of the second binding site are at least partly hybridized.

Abstract: Provided herein are methods and compositions for treating spinal conditions. In particular, use of double-stranded oligonucleotide decoys capable of binding to the DNA binding sites of two transcription factors (NF-?B and STAT6) for treatment of intervertebral disc degeneration, regenerating a chondrocyte extracellular matrix, spinal pain, and promoting synthesis of proteoglycan in intervertebral disc cells.

Abstract: The present invention provides an antibacterial composition capable of forming an antibacterial film having suppressed coloration, excellent antibacterial property, and suppressed film cracking, antibacterial film, and an antibacterial film-attached substrate. The antibacterial composition of the present invention includes a silver-based antibacterial agent containing zirconium phosphate and silver carried and supported on the zirconium phosphate, a monomer having a polymerizable group, and a solvent. The monomer having a polymerizable group includes a first monomer having a polymerizable group and a hydrophilic group, and a second monomer having a polymerizable group and having no hydrophilic group, and the content of the first monomer is 30% to 70% by mass with respect to the total mass of the monomer having a polymerizable group.

Abstract: Disclosed is a double-stranded oligonucleotide decoy including two transcription factor-binding sites, while keeping its size small. The double-stranded oligonucleotide decoy showing binding affinities for two transcription factors includes a first binding site for a first transcription factor and a second binding site for a second transcription factor. A first strand including the sense strand of the first binding site and a second strand including the sense strand of the second binding site are hybridized to form a double strand in which the sense strand of the first binding site and the sense strand of the second binding site are at least partly hybridized.

Abstract: In a pressure-sensitive adhesive microcapsule, a radiation-curable gluing agent is encapsulated by a wall film, and the average particle diameter is smaller than 500 ?m. A pressure-sensitive adhesive microcapsule-containing liquid includes the pressure-sensitive adhesive microcapsule and a binder. A gluing sheet includes a layer including the pressure-sensitive adhesive microcapsule on a support. A method for manufacturing the gluing sheet includes forming a layer including a pressure-sensitive adhesive microcapsule on a support by applying the pressure-sensitive adhesive microcapsule-containing liquid onto the support and then carrying out radiation irradiation. A method for manufacturing a laminate includes gluing the gluing sheet and an adherend by bringing a surface of the layer including the pressure-sensitive adhesive microcapsule in the gluing sheet and the adherend into contact with each other and compressing them together.

Abstract: A pressure sensitive adhesive sheet includes a transparent sheet base material, a first pressure sensitive adhesive layer, and a second pressure sensitive adhesive layer, and a pressure sensitive adhesive strength by a pressure of 1 N/cm2 or less is 0 N/25 mm. The first pressure sensitive adhesive layer includes a first silicone-based pressure sensitive adhesive and the second pressure sensitive adhesive layer has a second silicone-based pressure sensitive adhesive and a plurality of protrusions formed of a plurality of fine particles. A first sheet surface is a surface to adhere to an adherend. An average particle diameter of the fine particles is 2 ?m or more and 15 ?m or less and a coverage ratio of the first sheet surface with the fine particles is 10% or more and 70% or less.

Abstract: An object of the present invention is to provide an ink jet recording medium which exhibits excellent adhesiveness with respect to an ink and has excellent scratch resistance and in which density unevenness at the time of printing is suppressed, a method for manufacturing the ink jet recording medium, a printed material using the ink jet recording medium, a method for manufacturing the printed material, ornamental glass, and a roll. An ink jet recording medium of the present invention has a support and an ink receiving layer on at least one surface of the support, in which the ink receiving layer is a cured layer of a composition containing a radical polymerizable compound, a polymerization initiator, and a compound represented by Formula C-1.

Abstract: An oral preparation for the prophylaxis or treatment of a disease with infection by a pathogen, containing a killed lactic acid bacterium expressing, on the surface, an antigen of the pathogen, or a microparticulated form thereof, which has an average particle size of 2.68-30 ?m. An oral preparation for inducing cellular immunity to a target antigen, containing a killed lactic acid bacterium expressing the target antigen on the surface or a microparticulated form thereof, which has a particle size of 2.68-30 ?m.

Abstract: Provided is an inkjet recording sheet which includes a transparent support and an ink receiving layer disposed on one surface of the transparent support, in which the ink receiving layer is a layer formed by curing a composition containing at least a polymerization initiator and a polymerizable compound. When a printed article and ornamental glass are manufactured by forming an image portion by an inkjet method, the inkjet recording sheet is excellent in both the ink adhesiveness and the scratch resistance of the ink receiving layer including the image portion and a non-image portion. Also provided is a method for manufacturing an inkjet recording sheet, a printed article, a method for manufacturing a printed article, and ornamental glass.

Abstract: An object of the present invention is to provide an ink jet recording medium which exhibits excellent adhesiveness with respect to an ink and has excellent scratch resistance and in which density unevenness at the time of printing is suppressed, a method for manufacturing the ink jet recording medium, a printed material using the ink jet recording medium, a method for manufacturing the printed material, ornamental glass, and a roll. An ink jet recording medium of the present invention has a support and an ink receiving layer on at least one surface of the support, in which the ink receiving layer is a cured layer of a composition containing a radical polymerizable compound, a polymerization initiator, and a compound represented by Formula C-1.

Abstract: In a pressure-sensitive adhesive microcapsule, a radiation-curable gluing agent is encapsulated by a wall film, and the average particle diameter is smaller than 500 ?m. A pressure-sensitive adhesive microcapsule-containing liquid includes the pressure-sensitive adhesive microcapsule and a binder. A gluing sheet includes a layer including the pressure-sensitive adhesive microcapsule on a support. A method for manufacturing the gluing sheet includes forming a layer including a pressure-sensitive adhesive microcapsule on a support by applying the pressure-sensitive adhesive microcapsule-containing liquid onto the support and then carrying out radiation irradiation. A method for manufacturing a laminate includes gluing the gluing sheet and an adherend by bringing a surface of the layer including the pressure-sensitive adhesive microcapsule in the gluing sheet and the adherend into contact with each other and compressing them together.

Abstract: Provided is an inkjet recording sheet which includes a transparent support and an ink receiving layer disposed on one surface of the transparent support, in which the ink receiving layer is a layer formed by curing a composition containing at least a polymerization initiator and a polymerizable compound. When a printed article and ornamental glass are manufactured by forming an image portion by an inkjet method, the inkjet recording sheet is excellent in both the ink adhesiveness and the scratch resistance of the ink receiving layer including the image portion and a non-image portion. Also provided is a method for manufacturing an inkjet recording sheet, a printed article, a method for manufacturing a printed article, and ornamental glass.

Abstract: An oral preparation for the prophylaxis or treatment of a disease with infection by a pathogen, containing a killed lactic acid bacterium expressing, on the surface, an antigen of the pathogen, or a microparticulated form thereof, which has an average particle size of 2.68-30 ?m. An oral preparation for inducing cellular immunity to a target antigen, containing a killed lactic acid bacterium expressing the target antigen on the surface or a microparticulated form thereof, which has a particle size of 2.68-30 ?m.

Abstract: The method includes: forming a coating film including particles and an ultraviolet curable resin on a film substrate; and curing the ultraviolet curable resin by ultraviolet irradiation to form an anti-glare layer constituted by the particles and the ultraviolet curable resin. A ratio of a thickness A of the anti-glare layer to a diameter B of the particles is in the range of 1.5 to 2.4. The ultraviolet irradiation is performed with two or more ultraviolet irradiation units, the first unit irradiation amount is 49 mJ/cm2 or less, the second and subsequent units irradiation amount is greater than 50 mJ/cm2, and the total irradiation amount is 100 mJ/cm2 or greater. The oxygen concentration at a position which is 1 mm above a surface of the coating film is 1 ppm to 2000 ppm. The first unit irradiation is performed above a roller with surface temperature of 10° C. to 24° C.

Abstract: The method includes: forming a coating film including particles and an ultraviolet curable resin on a film substrate; and curing the ultraviolet curable resin by ultraviolet irradiation to form an anti-glare layer constituted by the particles and the ultraviolet curable resin. A ratio of a thickness A of the anti-glare layer to a diameter B of the particles is in the range of 1.5 to 2.4. The ultraviolet irradiation is performed with two or more ultraviolet irradiation units, the first unit irradiation amount is 49 mJ/cm2 or less, the second and subsequent units irradiation amount is greater than 50 mJ/cm2, and the total irradiation amount is 100 mJ/cm2 or greater. The oxygen concentration at a position which is 1 mm above a surface of the coating film is 1 ppm to 2000 ppm. The first unit irradiation is performed above a roller with surface temperature of 10° C. to 24° C.

Abstract: A cyclic amine is defined by the formula: ##STR1## in which A is naphthyl, phenyl, quinolyl or alkyl, X is a group containing carbonyl, n is 2 or 3 and B is alkyl, halogen, phenyl or --YZ, Y being --0--, --CO-- or --NH--, Z being phenyl, naphthyl, pyridyl, alkyl or cycloalkyl. It is useful to treat a mental symptoms associated with a cerebrovascular disease.

Abstract: A cyclic amine is defined by the formula: ##STR1## in which A is naphthyl, phenyl, quinolyl or alkyl, X is a group containing carbonyl, n is 2 or 3 and B is alkyl, halogen, phenyl or --YZ, Y being --O--, --CO-- or --NH--, Z being phenyl, naphthyl, pyridyl, alkyl or cycloalkyl. It is useful to treat mental symptoms associated with a cerebrovascular disease.