Patents by Inventor Takahiro Tanimoto
Takahiro Tanimoto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230122491Abstract: The present invention provides a composition for a non-aqueous patch preparation having an excellent adhesibility which can sustainedly release a drug. The patch preparation of the present invention can improve the adhesibility thereof as well as the release property of a drug by the addition of powder ingredient (e.g. a filler). As a result, the long-time sustention of the adhesibility of patch preparations can achieve the improvement of the transdermal absorbability and the sustained release of a drug. By the use of a composition for a patch preparation comprising this powder ingredient, a drug, regardless of the type of a drug is dissolved in an organic solvent or an ionic liquid to prepare a drug solution comprising the organic solvent, the drug solution is incorporated into the non-aqueous patch preparation of the present invention, and thereby a preparation with the improved transdermal-absorbability and sustained release can prepared.Type: ApplicationFiled: December 16, 2022Publication date: April 20, 2023Applicant: MEDRX CO., LTD.Inventors: Hidetoshi Hamamoto, Katsuhiro Yamanaka, Takahiro Tanimoto
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Patent number: 11559519Abstract: An object of the present invention is to provide a method for the treatment of a patient suffering from spasticity comprising administering to said patient a modified release dosage form comprising tizanidine or a pharmaceutically acceptable salt thereof. The present invention relates to a method of administering a transdermal patch preparation comprising tizanidine or a pharmaceutically acceptable salt thereof to a subject in need thereof, wherein the transdermal patch preparation releases about 4 mg to about 36 mg of tizanidine or a pharmaceutically acceptable salt thereof for at least about 24 hours.Type: GrantFiled: January 31, 2019Date of Patent: January 24, 2023Assignee: MEDRX, CO., LTD.Inventors: Yasushi Miwa, Hidetoshi Hamamoto, Naoya Akazawa, Takahiro Tanimoto
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Publication number: 20210346311Abstract: The present invention provides a composition for a non-aqueous patch preparation having an excellent adhesibility which can sustainedly release a drug. The patch preparation of the present invention can improve the adhesibility thereof as well as the release property of a drug by the addition of powder ingredient (e.g. a filler). As a result, the long-time sustention of the adhesibility of patch preparations can achieve the improvement of the transdermal absorbability and the sustained release of a drug. By the use of a composition for a patch preparation comprising this powder ingredient, a drug, regardless of the type of a drug is dissolved in an organic solvent or an ionic liquid to prepare a drug solution comprising the organic solvent, the drug solution is incorporated into the non-aqueous patch preparation of the present invention, and thereby a preparation with the improved transdermal-absorbability and sustained release can prepared.Type: ApplicationFiled: March 19, 2021Publication date: November 11, 2021Applicant: MEDRX CO., LTD.Inventors: Hidetoshi Hamamoto, Katsuhiro Yamanaka, Takahiro Tanimoto
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Publication number: 20210030724Abstract: An object of the present invention is to provide a method for the treatment of a patient suffering from spasticity comprising administering to said patient a modified release dosage form comprising tizanidine or a pharmaceutically acceptable salt thereof. The present invention relates to a method of administering a transdermal patch preparation comprising tizanidine or a pharmaceutically acceptable salt thereof to a subject in need thereof, wherein the transdermal patch preparation releases about 4 mg to about 36 mg of tizanidine or a pharmaceutically acceptable salt thereof for at least about 24 hours.Type: ApplicationFiled: January 31, 2019Publication date: February 4, 2021Applicant: MEDRx Co., Ltd.Inventors: Yasushi Miwa, Hidetoshi Hamamoto, Naoya Akazawa, Takahiro Tanimoto
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Patent number: 10639374Abstract: An object of the present invention is to provide a patch preparation having an excellent skin permeability of medicament using an acid additional salt of basic medicament. Provided is a patch preparation comprising a support and an adhesive layer on one surface of the support, wherein the adhesive layer contains a basic medicament, a fatty acid-based ionic liquid, and potassium salts and/or potassium ions. Said potassium salts and/or potassium ions are generated as a result of reaction of an acid addition salt of the basic medicament with a compound capable of generating potassium ion in the adhesive layer.Type: GrantFiled: June 7, 2018Date of Patent: May 5, 2020Assignee: MEDRx CO., LTDInventors: Hidetoshi Hamamoto, Takahiro Tanimoto
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Composition for patch preparation comprising drug, organic solvent, lipophilic mass base, and powder
Patent number: 10543275Abstract: The present disclosure provides a composition for a non-aqueous patch preparation with excellent adhesibility which can sustainedly release a drug. The patch preparation can improve the adhesibility of the patch preparation and the release property of a drug by the addition of a powder ingredient the long-time sustention of the adhesibility of tape preparations enables an improvement of the transdermal absorbability and the sustained release of a drug.Type: GrantFiled: June 18, 2013Date of Patent: January 28, 2020Assignee: MEDRX CO., LTD.Inventors: Hidetoshi Hamamoto, Katsuhiro Yamanaka, Takahiro Tanimoto -
Publication number: 20200000738Abstract: The present invention provides a composition for a non-aqueous patch preparation having an excellent adhesibility which can sustainedly release a drug. The patch preparation of the present invention can improve the adhesibility thereof as well as the release property of a drug by the addition of powder ingredient (e.g. a filler). As a result, the long-time sustention of the adhesibility of patch preparations can achieve the improvement of the transdermal absorbability and the sustained release of a drug. By the use of a composition for a patch preparation comprising this powder ingredient, a drug, regardless of the type of a drug is dissolved in an organic solvent or an ionic liquid to prepare a drug solution comprising the organic solvent, the drug solution is incorporated into the non-aqueous patch preparation of the present invention, and thereby a preparation with the improved transdermal-absorbability and sustained release can prepared.Type: ApplicationFiled: September 10, 2019Publication date: January 2, 2020Applicant: MEDRX CO., LTD.Inventors: Hidetoshi Hamamoto, Katsuhiro Yamanaka, Takahiro Tanimoto
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Composition for Patch Preparation Comprising Drug, Organic Solvent, Lipophilic Mass Base, and Powder
Publication number: 20190388544Abstract: The object of the present invention is to provide a composition for a non-aqueous patch preparation with excellent adhesibility which can sustainedly release a drug. The patch preparation of the present invention can improve the adhesibility of the patch preparation and the release property of a drug by the addition of a powder ingredient (a filler or the like). As a result, the long-time sustention of the adhesibility of tape preparations enables an improvement of the transdermal absorbability and the sustained release of a drug. By the use of a composition for a patch preparation comprising this powder ingredient, a drug, regardless of the type of a drug is dissolved in an organic solvent or an ionic liquid to prepare a drug solution comprising the organic solvent, the drug solution is incorporated into the non-aqueous patch preparation of the present invention, and thereby a preparation with the improved transdermal absorbability and the improved sustained release can prepared.Type: ApplicationFiled: September 9, 2019Publication date: December 26, 2019Applicant: MEDRX CO., LTD.Inventors: Hidetoshi Hamamoto, Katsuhiro Yamanaka, Takahiro Tanimoto -
Publication number: 20180325837Abstract: The present invention provides a composition for a non-aqueous patch preparation having an excellent adhesibility which can sustainedly release a drug. The patch preparation of the present invention can improve the adhesibility thereof as well as the release property of a drug by the addition of powder ingredient (e.g. a filler). As a result, the long-time sustention of the adhesibility of patch preparations can achieve the improvement of the transdermal absorbability and the sustained release of a drug. By the use of a composition for a patch preparation comprising this powder ingredient, a drug, regardless of the type of a drug is dissolved in an organic solvent or an ionic liquid to prepare a drug solution comprising the organic solvent, the drug solution is incorporated into the non-aqueous patch preparation of the present invention, and thereby a preparation with the improved transdermal-absorbability and sustained release can prepared.Type: ApplicationFiled: May 9, 2018Publication date: November 15, 2018Applicant: MEDRX CO., LTD.Inventors: Hidetoshi Hamamoto, Katsuhiro Yamanaka, Takahiro Tanimoto
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Publication number: 20180280513Abstract: An object of the present invention is to provide a patch preparation having an excellent skin permeability of medicament using an acid additional salt of basic medicament. Provided is a patch preparation comprising a support and an adhesive layer on one surface of the support, wherein the adhesive layer contains a basic medicament, a fatty acid-based ionic liquid, and potassium salts and/or potassium ions. Said potassium salts and/or potassium ions are generated as a result of reaction of an acid addition salt of the basic medicament with a compound capable of generating potassium ion in the adhesive layer.Type: ApplicationFiled: June 7, 2018Publication date: October 4, 2018Inventors: Hidetoshi Hamamoto, Takahiro Tanimoto
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Patent number: 10016502Abstract: An object of the present invention is to provide a patch preparation having an excellent skin permeability of medicament using an acid additional salt of basic medicament. Provided is a patch preparation comprising a support and an adhesive layer on one surface of the support, wherein the adhesive layer contains a basic medicament, a fatty acid-based ionic liquid, and potassium salts and/or potassium ions. Said potassium salts and/or potassium ions are generated as a result of reaction of an acid addition salt of the basic medicament with a compound capable of generating potassium ion in the adhesive layer.Type: GrantFiled: September 28, 2016Date of Patent: July 10, 2018Assignee: MEDRx Co., LTDInventors: Hidetoshi Hamamoto, Takahiro Tanimoto
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Patent number: 9980920Abstract: The present invention provides a composition for a non-aqueous patch preparation having an excellent adhesibility which can sustainedly release a drug. The patch preparation of the present invention can improve the adhesibility thereof as well as the release property of a drug by the addition of powder ingredient (e.g. a filler). As a result, the long-time sustention of the adhesibility of patch preparations can achieve the improvement of the transdermal absorbability and the sustained release of a drug. By the use of a composition for a patch preparation comprising this powder ingredient, a drug, regardless of the type of a drug is dissolved in an organic solvent or an ionic liquid to prepare a drug solution comprising the organic solvent, the drug solution is incorporated into the non-aqueous patch preparation of the present invention, and thereby a preparation with the improved transdermal-absorbability and sustained release can prepared.Type: GrantFiled: September 10, 2014Date of Patent: May 29, 2018Assignee: MEDRx Co., Ltd.Inventors: Hidetoshi Hamamoto, Katsuhiro Yamanaka, Takahiro Tanimoto
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Publication number: 20170056503Abstract: An object of the present invention is to provide a patch preparation having an excellent skin permeability of medicament using an acid additional salt of basic medicament. Provided is a patch preparation comprising a support and an adhesive layer on one surface of the support, wherein the adhesive layer contains a basic medicament, a fatty acid-based ionic liquid, and potassium salts and/or potassium ions. Said potassium salts and/or potassium ions are generated as a result of reaction of an acid addition salt of the basic medicament with a compound capable of generating potassium ion in the adhesive layer.Type: ApplicationFiled: September 28, 2016Publication date: March 2, 2017Inventors: Hidetoshi Hamamoto, Takahiro Tanimoto
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Publication number: 20160220506Abstract: The object of the present invention is to provide a composition for a non-aqueous patch preparation having an excellent adhesibility which can sustainedly release a drug. The patch preparation of the present invention can improve the adhesibility thereof as well as the release property of a drug by the addition of powder ingredient (e.g. a filler). As a result, the long-time sustention of the adhesibility of patch preparations can achieve the improvement of the transdermal absorbability and the sustained release of a drug. By the use of a composition for a patch preparation comprising this powder ingredient, a drug, regardless of the type of a drug is dissolved in an organic solvent or an ionic liquid to prepare a drug solution comprising the organic solvent, the drug solution is incorporated into the non-aqueous patch preparation of the present invention, and thereby a preparation with the improved transdermal-absorbability and sustained release can prepared.Type: ApplicationFiled: September 10, 2014Publication date: August 4, 2016Applicant: MEDRX CO., LTD.Inventors: Hidetoshi Hamamoto, Katsuhiro Yamanaka, Takahiro Tanimoto
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Composition for Patch Preparation Comprising Drug, Organic Solvent, Lipophilic Mass Base, and Powder
Publication number: 20150174249Abstract: The present disclosure provides a composition for a non-aqueous patch preparation with excellent adhesibility which can sustainedly release a drug. The patch preparation can improve the adhesibility of the patch preparation and the release property of a drug by the addition of a powder ingredient the long-time sustention of the adhesibility of tape preparations enables an improvement of the transdermal absorbability and the sustained release of a drug.Type: ApplicationFiled: June 18, 2013Publication date: June 25, 2015Applicant: MEDRX CO., LTD.Inventors: Hidetoshi Hamamoto, Katsuhiro Yamanaka, Takahiro Tanimoto -
Patent number: 8568746Abstract: Disclosed is a transdermal composition, which uses high-purity phosphatidylcholine that is most susceptible to oxidation and the like, and which exhibits high stability and high migration into the skin. Specifically, a transdermal composition having good stability and migration into the skin is able to be obtained by preparing a transdermal composition (a colloidal dispersion liquid of phosphatidylcholine) that contains high-purity phosphatidylcholine, carnitine, a polyhydric alcohol and water. Since the transdermal composition does not contain an oleaginous base (an oil component), the transdermal composition has skin compatibility and is thus useful as a therapeutic agent or a cosmetic preparation. In addition, phosphatidylcholine and carnitine have an effect of achieving good migration into the skin and are capable of promoting systemic or local lipid metabolism in subcutaneous adipose tissues.Type: GrantFiled: May 21, 2010Date of Patent: October 29, 2013Assignee: MEDRx Co., Ltd.Inventors: Keiko Yamasaki, Takahiro Tanimoto
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Publication number: 20120149664Abstract: Disclosed is a transdermal composition, which uses high-purity phosphatidylcholine that is most susceptible to oxidation and the like, and which exhibits high stability and high migration into the skin. Specifically, a transdermal composition having good stability and migration into the skin is able to be obtained by preparing a transdermal composition (a colloidal dispersion liquid of phosphatidylcholine) that contains high-purity phosphatidylcholine, carnitine, a polyhydric alcohol and water. Since the transdermal composition does not contain an oleaginous base (an oil component), the transdermal composition has skin compatibility and is thus useful as a therapeutic agent or a cosmetic preparation. In addition, phosphatidylcholine and carnitine have an effect of achieving good migration into the skin and are capable of promoting systemic or local lipid metabolism in subcutaneous adipose tissues.Type: ApplicationFiled: May 21, 2010Publication date: June 14, 2012Inventors: Keiko Yamasaki, Takahiro Tanimoto