Patents by Inventor Takahiro Tsukimura

Takahiro Tsukimura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PHARMACEUTICAL COMBINATION FOR TREATMENT OF FABRY DISEASE AND USE THEREOF
    Publication number: 20200115698
    Abstract: The present invention provides a pharmaceutical combination for treatment of Fabry disease and use thereof. The present invention relates to a pharmaceutical combination for treating Fabry disease, and the pharmaceutical combination includes (i) a protein which has mutations in an amino acid sequence of ?-N-acetylgalactosaminidase and has ?-galactosidase activity and (ii) an active site specific chaperone.
    Type: Application
    Filed: June 14, 2018
    Publication date: April 16, 2020
    Inventors: Takahiro TSUKIMURA, Tadayasu TOGAWA, Hitoshi SAKURABA
  • RRECOMBINANT HUMAN SAPOSIN B PROTEIN CONTAINING PHOSPHORYLATED GLUCOSE RING AND USE THEREOF
    Publication number: 20140219988
    Abstract: The present invention provides a means to ensure a further increase in the therapeutic effects provided by enzyme replacement therapy against lysosomal disease. The present invention is directed to a recombinant human saposin B protein containing phosphorylated carbohydrate chains, a lysosomal enzyme activator comprising such a recombinant protein, and a pharmaceutical composition for treatment of lysosomal disease, which comprises such a recombinant protein and a lysosomal enzyme, etc.
    Type: Application
    Filed: November 21, 2011
    Publication date: August 7, 2014
    Applicant: TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE
    Inventors: Hitoshi Sakuraba, Tadayasu Togawa, Takahiro Tsukimura, Yasunori Chiba, Toru Watanabe, Ikuo Kawashima