Patents by Inventor Takahiro TSUSHIMA

Takahiro TSUSHIMA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • THERAPEUTIC AGENT FOR CARTILAGE DISORDER
    Publication number: 20210386823
    Abstract: The inventors of the present invention searched for a substance that is effective in treating a cartilage disorder, and as a result, found that, in an animal model of joint cartilage deficiency, an HMGB1 fragment peptide having a specific amino acid sequence exhibits the effect of reproducing a healthy cartilage tissue including a hyaline cartilage. Based on this finding, the present invention provides a pharmaceutical composition that contains the specific HMGB1 fragment peptide and that is for preventing and/or treating a cartilage disorder.
    Type: Application
    Filed: October 25, 2019
    Publication date: December 16, 2021
    Applicants: OSAKA UNIVERSITY, STEMRIM INC.
    Inventors: Katsuto TAMAI, Takashi SHIMBO, Eiji SASAKI, Takahiro TSUSHIMA, Takehiko YAMAZAKI