Patents by Inventor Takahisa Sakaguchi

Takahisa Sakaguchi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HIGH CONCENTRATION ANTI-Abeta PROTOFIBRIL ANTIBODY FORMULATIONS AND METHODS OF USE THEREOF
    Publication number: 20230183328
    Abstract: Provided herein are aqueous pharmaceutical formulations comprising high concentrations of anisolated anti-A? protofibril antibody or a fragment thereof that binds to human A? protofibrils, such as BAN2401, arginine, polysorbate 80, and a pharmaceutically acceptable buffer.
    Type: Application
    Filed: March 19, 2021
    Publication date: June 15, 2023
    Inventors: Nobuo YOSHIDA, Naomi SAKURAMOTO, Takahisa SAKAGUCHI, Hirokazu KITO, Takahiro OZAWA, Anjali JOSHI, Yung Yueh HSU, Pierre SOUILLAC
  • Method for suppressing bitterness of quinoline derivative
    Patent number: 11090386
    Abstract: The present invention provides a method for suppressing bitterness of a quinoline derivative.
    Type: Grant
    Filed: July 18, 2018
    Date of Patent: August 17, 2021
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Kentaro Nagane, Yosuke Ueki, Shusuke Sano, Takahisa Sakaguchi
  • Container
    Patent number: 10865011
    Abstract: Provided is a container including a main body, a lid body, and a fixing mechanism that fixes the lid body to prevent the lid body from opening from the main body when the lid body is closed, the fixing being released when the lid body moves to a front side with respect to the main body. Cutouts are formed in side plates of the main body. The container is configured such that, by a rear plate tilting forward toward the cutouts of the side plates, the lid body moves to the front side with respect to the main body and the fixing of the lid body is released, and as the rear plate and a top plate of the lid body form a single plane, the top plate rises and the lid body opens.
    Type: Grant
    Filed: January 5, 2018
    Date of Patent: December 15, 2020
    Assignee: Eisai R&D Management Co., Ltd.
    Inventor: Takahisa Sakaguchi
  • CONTAINER
    Publication number: 20200062442
    Abstract: Provided is a container including a main body, a lid body, and a fixing mechanism that fixes the lid body to prevent the lid body from opening from the main body when the lid body is closed, the fixing being released when the lid body moves to a front side with respect to the main body. Cutouts are formed in side plates of the main body. The container is configured such that, by a rear plate tilting forward toward the cutouts of the side plates, the lid body moves to the front side with respect to the main body and the fixing of the lid body is released, and as the rear plate and a top plate of the lid body form a single plane, the top plate rises and the lid body opens.
    Type: Application
    Filed: January 5, 2018
    Publication date: February 27, 2020
    Applicant: Eisai R&D Management Co., Ltd.
    Inventor: Takahisa Sakaguchi
  • Method for Suppressing Bitterness of Quinoline Derivative
    Publication number: 20180318422
    Abstract: The present invention provides a method for suppressing bitterness of a quinoline derivative.
    Type: Application
    Filed: July 18, 2018
    Publication date: November 8, 2018
    Applicant: Eisai R&D Management Co., Ltd.
    Inventors: Kentaro Nagane, Yosuke Ueki, Shusuke Sano, Takahisa Sakaguchi
  • Method for Suppressing Bitterness of Quinoline Derivative
    Publication number: 20180028662
    Abstract: The present invention provides a method for suppressing bitterness of a quinoline derivative.
    Type: Application
    Filed: February 23, 2016
    Publication date: February 1, 2018
    Inventors: Kentaro Nagane, Yosuke Ueki, Shusuke Sano, Takahisa Sakaguchi
  • Phenoxypyridine derivative salts and crystals thereof, and process for preparing the same
    Patent number: 8377938
    Abstract: The invention provides acid addition salts of the compounds represented by formula (1) or (2), or crystals thereof, and processes for preparing the same. The salts or crystals have HGFR inhibitory activity and excellent physical properties (solubility, safety, etc.) and are therefore useful as anti-tumor agents, angiogenesis inhibitors and inhibitors for metastasis for a various types of tumor.
    Type: Grant
    Filed: February 14, 2008
    Date of Patent: February 19, 2013
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Tomohiro Matsushima, Shuji Shirotori, Keiko Takahashi, Atsushi Kamada, Kazunori Wakasugi, Takahisa Sakaguchi
  • Process for preparing phenoxypyridine derivatives
    Patent number: 7790885
    Abstract: A process for preparing a compound represented by the formula (I): comprising reacting a compound represented by the formula (II) or salt thereof: with a compound represented by the formula (III): in the presence of a condensation reagent, wherein R1 represents 1) optionally substituted azetidin-1-yl, 2) optionally substituted pyrrolidin-1-yl, 3) optionally substituted piperidin-1-yl, etc.; R2, R3, R4 and R5 may be the same or different and each represents hydrogen or fluorine; and R6 represents hydrogen or fluorine.
    Type: Grant
    Filed: August 27, 2007
    Date of Patent: September 7, 2010
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Mitsuo Nagai, Tomohiro Matsushima, Atsushi Kamada, Kazunori Wakasugi, Shuji Shirotori, Shinya Abe, Kazumasa Nara, Takahisa Sakaguchi
  • Crystalline form of the salt of 4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide or the solvate of the salt and a process for preparing the same
    Patent number: 7612208
    Abstract: A crystal of a 4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide hydrochloride, hydrobromide, p-toluenesulfonate, sulfate, methanesulfonate or ethanesulfonate, or a solvate thereof.
    Type: Grant
    Filed: December 22, 2004
    Date of Patent: November 3, 2009
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Tomohiro Matsushima, Taiju Nakamura, Kazuhiro Yoshizawa, Atsushi Kamada, Yusuke Ayata, Naoko Suzuki, Itaru Arimoto, Takahisa Sakaguchi, Masaharu Gotoda
  • Amorphous salt of 4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide and process for preparing the same
    Patent number: 7550483
    Abstract: An amorphous form of a salt of 4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide.
    Type: Grant
    Filed: June 22, 2006
    Date of Patent: June 23, 2009
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Takahisa Sakaguchi, Akihiko Tsuruoka
  • PHENOXYPYRIDINE DERIVATIVE SALTS AND CRYSTALS THEREOF, AND PROCESS FOR PREPARING THE SAME
    Publication number: 20080318924
    Abstract: The invention provides acid addition salts of the compounds represented by formula (1) or (2), or crystals thereof, and processes for preparing the same. The salts or crystals have HGFR inhibitory activity and excellent physical properties (solubility, safety, etc.) and are therefore useful as anti-tumor agents, angiogenesis inhibitors and inhibitors for metastasis for a various types of tumor.
    Type: Application
    Filed: February 14, 2008
    Publication date: December 25, 2008
    Applicant: Eisai R&D Management Co., Ltd
    Inventors: Tomohiro MATSUSHIMA, Shuji Shirotori, Keiko Takahashi, Atsushi Kamada, Kazunori Wakasugi, Takahisa Sakaguchi
  • Crystal of Indole Derivative Having Piperidine Ring and Process for Production Thereof
    Publication number: 20080227815
    Abstract: A crystal of 1-[1-[2-(7-methoxy-2,2-dimethyl-4-oxochroman-8-yl)-ethyl]piperidin-4-yl]-N-methyl-1H-indole-6-carboxamide fumarate which has peaks at chemical shifts of about 124.0 ppm and about 26.8 ppm in a 13C solid NMR spectrum.
    Type: Application
    Filed: May 11, 2006
    Publication date: September 18, 2008
    Inventors: Takahisa Sakaguchi, Yuichi Suzuki, Koichi Ito, Jun Niijima, Mamoru Miyazawa, Toshikazu Shimizu, Masaharu Gotoda, Naoko Suzuki, Takashi Hasebe
  • Process for preparing phenoxypyridine derivatives
    Publication number: 20080214815
    Abstract: A process for preparing a compound represented by the formula (I): comprising reacting a compound represented by the formula (II) or salt thereof: with a compound represented by the formula (III): in the presence of a condensation reagent, wherein R1 represents 1) optionally substituted azetidin-1-yl, 2) optionally substituted pyrrolidin-1-yl, 3) optionally substituted piperidin-1-yl, etc.; R2, R3, R4 and R5 may be the same or different and each represents hydrogen or fluorine; and R6 represents hydrogen or fluorine.
    Type: Application
    Filed: August 27, 2007
    Publication date: September 4, 2008
    Applicant: Eisai R&D Management Co., Ltd.
    Inventors: Mitsuo Nagai, Tomohiro Matsushima, Atsushi Kamada, Kazunori Wakasugi, Shuji Shirotori, Shinya Abe, Kazumasa Nara, Takahisa Sakaguchi
  • Amorphous salt of 4-(3-chiloro-4-(cycloproplylaminocarbonyl)aminophenoxy)-7-method-6-quinolinecarboxamide and process for preparing the same
    Publication number: 20070004773
    Abstract: An amorphous form of a salt of 4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide.
    Type: Application
    Filed: June 22, 2006
    Publication date: January 4, 2007
    Applicant: Eisai R&D Management Co., Ltd.
    Inventors: Takahisa Sakaguchi, Akihiko Tsuruoka