Patents by Inventor Takahisa Takubo
Takahisa Takubo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240058225Abstract: [Problem] Providing a whitened capsule and a whitened film without using any white pigment such as titanium dioxide. [Solution] Provided is a film, a capsule, and a film forming composition, characterized by comprising: a film-forming polymer; and a whitening agent including either a surfactant or both a surfactant and a salt, and characterized in that the surfactant is selected from a fatty acid ester of polyhydric alcohol, a polyethylene glycol, a polypropylene glycol, a polyalkylene oxide derivative, an alkyl sulfate ester salt, and a saponin.Type: ApplicationFiled: September 21, 2023Publication date: February 22, 2024Applicant: Capsugel Belgium NVInventors: Kaori Sato, Takahisa Takubo, Hitomi Doi
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Patent number: 11878079Abstract: The instant disclosure provides a capsule composition comprising pullulan, a setting system and a surfactant system that is a sucroglyceride or a sugar fatty acid ester, and methods for making such capsules.Type: GrantFiled: December 22, 2022Date of Patent: January 23, 2024Assignee: Capsugel Belgium NVInventors: Takahisa Takubo, Claire Geneviève Odile Tardy
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Patent number: 11801205Abstract: [Problem] Providing a whitened capsule and a whitened film without using any white pigment such as titanium dioxide. [Solution] Provided is a film, a capsule, and a film forming composition, characterized by comprising: a film-forming polymer; and a whitening agent including either a surfactant or both a surfactant and a salt, and characterized in that the surfactant is selected from a fatty acid ester of polyhydric alcohol, a polyethylene glycol, a polypropylene glycol, a polyalkylene oxide derivative, an alkyl sulfate ester salt, and a saponin.Type: GrantFiled: July 3, 2019Date of Patent: October 31, 2023Assignee: Capsugel Belgium NVInventors: Kaori Sato, Takahisa Takubo, Hitomi Doi
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Publication number: 20230131084Abstract: The instant disclosure provides a capsule composition comprising pullulan, a setting system and a surfactant system that is a sucroglyceride or a sugar fatty acid ester, and methods for making such capsules.Type: ApplicationFiled: December 22, 2022Publication date: April 27, 2023Applicant: Capsugel Belgium NVInventors: Takahisa Takubo, Claire Geneviève Odile Tardy
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Patent number: 11576870Abstract: The instant disclosure provides a capsule composition comprising pullulan, a setting system and a surfactant system that is a sucroglyceride or a sugar fatty acid ester, and methods for making such capsules.Type: GrantFiled: April 10, 2018Date of Patent: February 14, 2023Assignee: Capsugel Belgium NVInventors: Takahisa Takubo, Claire Geneviève Odile Tardy
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Publication number: 20220218619Abstract: Problem to be solved: To provide a whitened or opacified capsule and film without using a white pigment such as titanium dioxide. Solution: A film, a capsule and a film-forming composition characterized by containing a film-forming polymer component selected from gelatin and pullulan and an opacifying agent consisting of a water-soluble salt except calcium salt carbonate and bicarbonate, wherein the salt is selected from a sodium salt, potassium salt, an ammonium salt and a magnesium salt.Type: ApplicationFiled: June 11, 2020Publication date: July 14, 2022Inventors: Takahisa Takubo, Hitomi Doi, Kaori Sato
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Publication number: 20220008296Abstract: [Technical Problem] A problem of the present invention is, in one aspect, to provide a capsule formulation including an active ingredient and the like that may deteriorate upon contacting an acid, wherein the capsule formulation makes it possible not to deteriorate the active ingredient and the like by a gastric acid which enters into a capsule film. [Technical Solution] A capsule formulation comprising an active ingredient and oil, wherein said capsule of said formulation is an enteric capsule comprising a water soluble film forming polymer and gellan gum; said oil is an oil acceptable for pharmaceuticals or foods; and said active ingredient is encapsulated in said capsule together with said oil, and the production method thereof, are provided.Type: ApplicationFiled: September 27, 2021Publication date: January 13, 2022Applicant: Capsugel Belgium NVInventors: Keith Hutchison, Takahisa Takubo
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Publication number: 20210275404Abstract: [Problem] Providing a whitened capsule and a whitened film without using any white pigment such as titanium dioxide. [Solution] Provided is a film, a capsule, and a film forming composition, characterized by comprising: a film-forming polymer; and a whitening agent including either a surfactant or both a surfactant and a salt, and characterized in that the surfactant is selected from a fatty acid ester of polyhydric alcohol, a polyethylene glycol, a polypropylene glycol, a polyalkylene oxide derivative, an alkyl sulfate ester salt, and a saponin.Type: ApplicationFiled: July 3, 2019Publication date: September 9, 2021Applicant: Capsugel Belgium NVInventors: Kaori Sato, Takahisa Takubo, Hitomi Doi
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Patent number: 10568839Abstract: The present disclosure concerns embodiments of hard pullulan capsule shells and capsules comprising (I) moisture, (II) a mono-, di-, and oligosaccharides free pullulan and (III) a setting system. Also provided are an aqueous composition and a dip-molding manufacturing method for the manufacture of such shells and capsules.Type: GrantFiled: May 10, 2018Date of Patent: February 25, 2020Assignee: Capsugel Belgium NVInventors: Dominique Nicolas Cade, Takahisa Takubo
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Publication number: 20190046454Abstract: Publicly available pullulan hard capsule shells present certain drawbacks, notably a non fully satisfactory shell mechanical strength (i.e. shell brittleness) at shell low LOD. Improving this property is a particularly desirable goal for pullulan hard capsule shells. The present invention solves this and other objects by providing new hard pullulan capsule shells and capsules comprising (I) moisture, (II) a mono-, di-, and oligosaccharides free pullulan and (III) a setting system. Also provided are an aqueous composition and a dip-molding manufacturing method for the manufacture of such shells and capsules.Type: ApplicationFiled: October 15, 2018Publication date: February 14, 2019Applicant: Capsugel Belgium NVInventors: Dominique Nicolas Cade, Takahisa Takubo
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Patent number: 10172803Abstract: A problem of the present disclosure is, in one embodiment, to create a hard capsule formulation that includes a pharmaceutical agent or the like whose components deteriorate upon contact with an acid, in which the pharmaceutical agent or the like does not deteriorate due to gastric acid penetrating into the outer shell of the hard capsule. A hard capsule formulation comprising a hard capsule with acid resistance, in which the hard capsule is not treated with enteric coating, and the hard capsule formulation comprises an agent to inhibit invasion of gastric fluid and a pharmaceutical agent in the hard capsule.Type: GrantFiled: March 3, 2014Date of Patent: January 8, 2019Assignee: Capsugel Belgium NVInventor: Takahisa Takubo
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Patent number: 10130587Abstract: The present disclosure concerns embodiments of new hard pullulan capsule shells and capsules comprising (I) moisture, (II) a mono-, di-, and oligosaccharides free pullulan and (III) a setting system. Also provided are an aqueous composition and a dip-molding manufacturing method for the manufacture of such shells and capsules.Type: GrantFiled: January 10, 2012Date of Patent: November 20, 2018Assignee: Capsugel Belgium NVInventors: Dominique Nicolas Cade, Takahisa Takubo
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Publication number: 20180256506Abstract: Publicly available pullulan hard capsule shells present certain drawbacks, notably a non fully satisfactory shell mechanical strength (i.e. shell brittleness) at shell low LOD. Improving this property is a particularly desirable goal for pullulan hard capsule shells. The present invention solves this and other objects by providing new hard pullulan capsule shells and capsules comprising (I) moisture, (II) a mono-, di-, and oligosaccharides free pullulan and (III) a setting system. Also provided are an aqueous composition and a dip-molding manufacturing method for the manufacture of such shells and capsules.Type: ApplicationFiled: May 10, 2018Publication date: September 13, 2018Applicant: Capsugel Belgium NVInventors: Dominique Nicolas Cade, Takahisa Takubo
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Publication number: 20170216146Abstract: Technical Problem A problem of the present invention is, in one aspect, to provide a capsule formulation including an active ingredient and the like that may deteriorate upon contacting an acid, wherein the capsule formulation makes it possible not to deteriorate the active ingredient and the like by a gastric acid which enters into a capsule film. Technical Solution A capsule formulation comprising an active ingredient and oil, wherein said capsule of said formulation is an enteric capsule comprising a water soluble film forming polymer and gellan gum; said oil is an oil acceptable for pharmaceuticals or foods; and said active ingredient is encapsulated in said capsule together with said oil, and the production method thereof, are provided.Type: ApplicationFiled: July 31, 2014Publication date: August 3, 2017Applicant: Capsugel Belgium NVInventors: Keith Hutchison, Takahisa Takubo
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Publication number: 20160015651Abstract: A problem of the present disclosure is, in one embodiment, to create a hard capsule formulation that includes a pharmaceutical agent or the like whose components deteriorate upon contact with an acid, in which the pharmaceutical agent or the like does not deteriorate due to gastric acid penetrating into the outer shell of the hard capsule. A hard capsule formulation comprising a hard capsule with acid resistance, in which the hard capsule is not treated with enteric coating, and the hard capsule formulation comprises an agent to inhibit invasion of gastric fluid and a pharmaceutical agent in the hard capsule.Type: ApplicationFiled: March 3, 2014Publication date: January 21, 2016Applicant: Capsugel Belgium NVInventor: Takahisa Takubo
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Publication number: 20150140084Abstract: The present disclosure relates to acid resistant banding solutions for two piece hard capsules, and methods of making the same. The present disclosure also relates, in part, to a method for banding such capsules which provides an acid resistant seal between the capsule parts and achieves an increased acid resistance in vitro. The instant disclosure further relates to a capsule sealing solution formula that comprises shellac ink or shellac ink vehicle component.Type: ApplicationFiled: May 20, 2013Publication date: May 21, 2015Applicant: Capsugel Belgium NVInventor: Takahisa Takubo
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Publication number: 20130287842Abstract: Publicly available pullulan hard capsule shells present certain drawbacks, notably a non fully satisfactory shell mechanical strength (i.e. shell brittleness) at shell low LOD. Improving this property is a particularly desirable goal for pullulan hard capsule shells. The present invention solves this and other objects by providing new hard pullulan capsule shells and capsules comprising (I) moisture, (II) a mono-, di-, and oligosaccharides free pullulan and (III) a setting system. Also provided are an aqueous composition and a dip-molding manufacturing method for the manufacture of such shells and capsules.Type: ApplicationFiled: January 10, 2012Publication date: October 31, 2013Applicant: Capsugel Belgium NVInventors: Dominique Nicolas Cade, Takahisa Takubo
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Publication number: 20040234591Abstract: A hard gelatin capsule is provided which comprises gelatin and titanium oxide having a secondary particle size of less than 10 &mgr;m and a median diameter of 0.5 &mgr;m or less being dispersed in the gelatin. A process for producing a hard gelatin capsule includes the steps of preparing a gelatin solution, dispersing titanium oxide in the gelatin solution so that a secondary particle size of the titanium oxide becomes less than 10 &mgr;m and a median diameter of the same becomes 0.5 &mgr;m or less, and molding the dispersion to prepare a capsule.Type: ApplicationFiled: May 7, 2004Publication date: November 25, 2004Inventors: Takahisa Takubo, Hiroshi Ohnuki, Eisaku Sai, Kenji Miyata, Hiroyoshi Kino
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Publication number: 20030219478Abstract: A capsule is made by filling a medical formulation, food or food additive which has an aldehyde group in the molecule, or readily forms an aldehyde group, into a capsule made of pullulan as a base.Type: ApplicationFiled: April 7, 2003Publication date: November 27, 2003Inventors: Hiroshi Ohnuki, Takahisa Takubo, Eisaku Sai, Kenji Miyata
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Publication number: 20030211257Abstract: The present invention relates to a hard capsule printed with ink comprising sepia pigment. As a result of using the ink comprising sepia pigment, the hard capsule that is printed with the ink comprising natural pigment and has legibly black printing can be provided.Type: ApplicationFiled: April 7, 2003Publication date: November 13, 2003Inventors: Kazuyoshi Taniguchi, Hiroshi Ohnuki, Takahisa Takubo, Eisaku Sai, Kenji Miyata