Patents by Inventor Takahisa Takubo

Takahisa Takubo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240058225
    Abstract: [Problem] Providing a whitened capsule and a whitened film without using any white pigment such as titanium dioxide. [Solution] Provided is a film, a capsule, and a film forming composition, characterized by comprising: a film-forming polymer; and a whitening agent including either a surfactant or both a surfactant and a salt, and characterized in that the surfactant is selected from a fatty acid ester of polyhydric alcohol, a polyethylene glycol, a polypropylene glycol, a polyalkylene oxide derivative, an alkyl sulfate ester salt, and a saponin.
    Type: Application
    Filed: September 21, 2023
    Publication date: February 22, 2024
    Applicant: Capsugel Belgium NV
    Inventors: Kaori Sato, Takahisa Takubo, Hitomi Doi
  • Patent number: 11878079
    Abstract: The instant disclosure provides a capsule composition comprising pullulan, a setting system and a surfactant system that is a sucroglyceride or a sugar fatty acid ester, and methods for making such capsules.
    Type: Grant
    Filed: December 22, 2022
    Date of Patent: January 23, 2024
    Assignee: Capsugel Belgium NV
    Inventors: Takahisa Takubo, Claire Geneviève Odile Tardy
  • Patent number: 11801205
    Abstract: [Problem] Providing a whitened capsule and a whitened film without using any white pigment such as titanium dioxide. [Solution] Provided is a film, a capsule, and a film forming composition, characterized by comprising: a film-forming polymer; and a whitening agent including either a surfactant or both a surfactant and a salt, and characterized in that the surfactant is selected from a fatty acid ester of polyhydric alcohol, a polyethylene glycol, a polypropylene glycol, a polyalkylene oxide derivative, an alkyl sulfate ester salt, and a saponin.
    Type: Grant
    Filed: July 3, 2019
    Date of Patent: October 31, 2023
    Assignee: Capsugel Belgium NV
    Inventors: Kaori Sato, Takahisa Takubo, Hitomi Doi
  • Publication number: 20230131084
    Abstract: The instant disclosure provides a capsule composition comprising pullulan, a setting system and a surfactant system that is a sucroglyceride or a sugar fatty acid ester, and methods for making such capsules.
    Type: Application
    Filed: December 22, 2022
    Publication date: April 27, 2023
    Applicant: Capsugel Belgium NV
    Inventors: Takahisa Takubo, Claire Geneviève Odile Tardy
  • Patent number: 11576870
    Abstract: The instant disclosure provides a capsule composition comprising pullulan, a setting system and a surfactant system that is a sucroglyceride or a sugar fatty acid ester, and methods for making such capsules.
    Type: Grant
    Filed: April 10, 2018
    Date of Patent: February 14, 2023
    Assignee: Capsugel Belgium NV
    Inventors: Takahisa Takubo, Claire Geneviève Odile Tardy
  • Publication number: 20220218619
    Abstract: Problem to be solved: To provide a whitened or opacified capsule and film without using a white pigment such as titanium dioxide. Solution: A film, a capsule and a film-forming composition characterized by containing a film-forming polymer component selected from gelatin and pullulan and an opacifying agent consisting of a water-soluble salt except calcium salt carbonate and bicarbonate, wherein the salt is selected from a sodium salt, potassium salt, an ammonium salt and a magnesium salt.
    Type: Application
    Filed: June 11, 2020
    Publication date: July 14, 2022
    Inventors: Takahisa Takubo, Hitomi Doi, Kaori Sato
  • Publication number: 20220008296
    Abstract: [Technical Problem] A problem of the present invention is, in one aspect, to provide a capsule formulation including an active ingredient and the like that may deteriorate upon contacting an acid, wherein the capsule formulation makes it possible not to deteriorate the active ingredient and the like by a gastric acid which enters into a capsule film. [Technical Solution] A capsule formulation comprising an active ingredient and oil, wherein said capsule of said formulation is an enteric capsule comprising a water soluble film forming polymer and gellan gum; said oil is an oil acceptable for pharmaceuticals or foods; and said active ingredient is encapsulated in said capsule together with said oil, and the production method thereof, are provided.
    Type: Application
    Filed: September 27, 2021
    Publication date: January 13, 2022
    Applicant: Capsugel Belgium NV
    Inventors: Keith Hutchison, Takahisa Takubo
  • Publication number: 20210275404
    Abstract: [Problem] Providing a whitened capsule and a whitened film without using any white pigment such as titanium dioxide. [Solution] Provided is a film, a capsule, and a film forming composition, characterized by comprising: a film-forming polymer; and a whitening agent including either a surfactant or both a surfactant and a salt, and characterized in that the surfactant is selected from a fatty acid ester of polyhydric alcohol, a polyethylene glycol, a polypropylene glycol, a polyalkylene oxide derivative, an alkyl sulfate ester salt, and a saponin.
    Type: Application
    Filed: July 3, 2019
    Publication date: September 9, 2021
    Applicant: Capsugel Belgium NV
    Inventors: Kaori Sato, Takahisa Takubo, Hitomi Doi
  • Patent number: 10568839
    Abstract: The present disclosure concerns embodiments of hard pullulan capsule shells and capsules comprising (I) moisture, (II) a mono-, di-, and oligosaccharides free pullulan and (III) a setting system. Also provided are an aqueous composition and a dip-molding manufacturing method for the manufacture of such shells and capsules.
    Type: Grant
    Filed: May 10, 2018
    Date of Patent: February 25, 2020
    Assignee: Capsugel Belgium NV
    Inventors: Dominique Nicolas Cade, Takahisa Takubo
  • Publication number: 20190046454
    Abstract: Publicly available pullulan hard capsule shells present certain drawbacks, notably a non fully satisfactory shell mechanical strength (i.e. shell brittleness) at shell low LOD. Improving this property is a particularly desirable goal for pullulan hard capsule shells. The present invention solves this and other objects by providing new hard pullulan capsule shells and capsules comprising (I) moisture, (II) a mono-, di-, and oligosaccharides free pullulan and (III) a setting system. Also provided are an aqueous composition and a dip-molding manufacturing method for the manufacture of such shells and capsules.
    Type: Application
    Filed: October 15, 2018
    Publication date: February 14, 2019
    Applicant: Capsugel Belgium NV
    Inventors: Dominique Nicolas Cade, Takahisa Takubo
  • Patent number: 10172803
    Abstract: A problem of the present disclosure is, in one embodiment, to create a hard capsule formulation that includes a pharmaceutical agent or the like whose components deteriorate upon contact with an acid, in which the pharmaceutical agent or the like does not deteriorate due to gastric acid penetrating into the outer shell of the hard capsule. A hard capsule formulation comprising a hard capsule with acid resistance, in which the hard capsule is not treated with enteric coating, and the hard capsule formulation comprises an agent to inhibit invasion of gastric fluid and a pharmaceutical agent in the hard capsule.
    Type: Grant
    Filed: March 3, 2014
    Date of Patent: January 8, 2019
    Assignee: Capsugel Belgium NV
    Inventor: Takahisa Takubo
  • Patent number: 10130587
    Abstract: The present disclosure concerns embodiments of new hard pullulan capsule shells and capsules comprising (I) moisture, (II) a mono-, di-, and oligosaccharides free pullulan and (III) a setting system. Also provided are an aqueous composition and a dip-molding manufacturing method for the manufacture of such shells and capsules.
    Type: Grant
    Filed: January 10, 2012
    Date of Patent: November 20, 2018
    Assignee: Capsugel Belgium NV
    Inventors: Dominique Nicolas Cade, Takahisa Takubo
  • Publication number: 20180256506
    Abstract: Publicly available pullulan hard capsule shells present certain drawbacks, notably a non fully satisfactory shell mechanical strength (i.e. shell brittleness) at shell low LOD. Improving this property is a particularly desirable goal for pullulan hard capsule shells. The present invention solves this and other objects by providing new hard pullulan capsule shells and capsules comprising (I) moisture, (II) a mono-, di-, and oligosaccharides free pullulan and (III) a setting system. Also provided are an aqueous composition and a dip-molding manufacturing method for the manufacture of such shells and capsules.
    Type: Application
    Filed: May 10, 2018
    Publication date: September 13, 2018
    Applicant: Capsugel Belgium NV
    Inventors: Dominique Nicolas Cade, Takahisa Takubo
  • Publication number: 20170216146
    Abstract: Technical Problem A problem of the present invention is, in one aspect, to provide a capsule formulation including an active ingredient and the like that may deteriorate upon contacting an acid, wherein the capsule formulation makes it possible not to deteriorate the active ingredient and the like by a gastric acid which enters into a capsule film. Technical Solution A capsule formulation comprising an active ingredient and oil, wherein said capsule of said formulation is an enteric capsule comprising a water soluble film forming polymer and gellan gum; said oil is an oil acceptable for pharmaceuticals or foods; and said active ingredient is encapsulated in said capsule together with said oil, and the production method thereof, are provided.
    Type: Application
    Filed: July 31, 2014
    Publication date: August 3, 2017
    Applicant: Capsugel Belgium NV
    Inventors: Keith Hutchison, Takahisa Takubo
  • Publication number: 20160015651
    Abstract: A problem of the present disclosure is, in one embodiment, to create a hard capsule formulation that includes a pharmaceutical agent or the like whose components deteriorate upon contact with an acid, in which the pharmaceutical agent or the like does not deteriorate due to gastric acid penetrating into the outer shell of the hard capsule. A hard capsule formulation comprising a hard capsule with acid resistance, in which the hard capsule is not treated with enteric coating, and the hard capsule formulation comprises an agent to inhibit invasion of gastric fluid and a pharmaceutical agent in the hard capsule.
    Type: Application
    Filed: March 3, 2014
    Publication date: January 21, 2016
    Applicant: Capsugel Belgium NV
    Inventor: Takahisa Takubo
  • Publication number: 20150140084
    Abstract: The present disclosure relates to acid resistant banding solutions for two piece hard capsules, and methods of making the same. The present disclosure also relates, in part, to a method for banding such capsules which provides an acid resistant seal between the capsule parts and achieves an increased acid resistance in vitro. The instant disclosure further relates to a capsule sealing solution formula that comprises shellac ink or shellac ink vehicle component.
    Type: Application
    Filed: May 20, 2013
    Publication date: May 21, 2015
    Applicant: Capsugel Belgium NV
    Inventor: Takahisa Takubo
  • Publication number: 20130287842
    Abstract: Publicly available pullulan hard capsule shells present certain drawbacks, notably a non fully satisfactory shell mechanical strength (i.e. shell brittleness) at shell low LOD. Improving this property is a particularly desirable goal for pullulan hard capsule shells. The present invention solves this and other objects by providing new hard pullulan capsule shells and capsules comprising (I) moisture, (II) a mono-, di-, and oligosaccharides free pullulan and (III) a setting system. Also provided are an aqueous composition and a dip-molding manufacturing method for the manufacture of such shells and capsules.
    Type: Application
    Filed: January 10, 2012
    Publication date: October 31, 2013
    Applicant: Capsugel Belgium NV
    Inventors: Dominique Nicolas Cade, Takahisa Takubo
  • Publication number: 20040234591
    Abstract: A hard gelatin capsule is provided which comprises gelatin and titanium oxide having a secondary particle size of less than 10 &mgr;m and a median diameter of 0.5 &mgr;m or less being dispersed in the gelatin. A process for producing a hard gelatin capsule includes the steps of preparing a gelatin solution, dispersing titanium oxide in the gelatin solution so that a secondary particle size of the titanium oxide becomes less than 10 &mgr;m and a median diameter of the same becomes 0.5 &mgr;m or less, and molding the dispersion to prepare a capsule.
    Type: Application
    Filed: May 7, 2004
    Publication date: November 25, 2004
    Inventors: Takahisa Takubo, Hiroshi Ohnuki, Eisaku Sai, Kenji Miyata, Hiroyoshi Kino
  • Publication number: 20030219478
    Abstract: A capsule is made by filling a medical formulation, food or food additive which has an aldehyde group in the molecule, or readily forms an aldehyde group, into a capsule made of pullulan as a base.
    Type: Application
    Filed: April 7, 2003
    Publication date: November 27, 2003
    Inventors: Hiroshi Ohnuki, Takahisa Takubo, Eisaku Sai, Kenji Miyata
  • Publication number: 20030211257
    Abstract: The present invention relates to a hard capsule printed with ink comprising sepia pigment. As a result of using the ink comprising sepia pigment, the hard capsule that is printed with the ink comprising natural pigment and has legibly black printing can be provided.
    Type: Application
    Filed: April 7, 2003
    Publication date: November 13, 2003
    Inventors: Kazuyoshi Taniguchi, Hiroshi Ohnuki, Takahisa Takubo, Eisaku Sai, Kenji Miyata