Patents by Inventor Takaki Momose

Takaki Momose has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CHIMERIC ANTIGEN RECEPTOR-EXPRESSING CELLS TARGETING ALK
    Publication number: 20220249561
    Abstract: The present invention is intended to develop a chimeric antigen receptor (CAR) that is effective against solid tumor expressing anaplastic lymphoma kinase (ALK). The present invention provides a polynucleotide encoding a CAR protein comprising a target binding domain binding to an extracellular ligand binding region of ALK, a transmembrane domain, and an intracellular signaling domain. The target binding domain of the polynucleotide is selected from among FAM150A, FAM150B, and fragments thereof binding to the extracellular ligand binding region of ALK. The present invention also provides a genetically modified cell comprising the polynucleotide introduced thereinto.
    Type: Application
    Filed: May 29, 2020
    Publication date: August 11, 2022
    Applicant: SHINSHU UNIVERSITY
    Inventors: Yozo Nakazawa, Shoji Saito, Shigeki Yagyu, Shigeru Nakano, Takaki Momose, Kenta Hitomi