Abstract: The present invention provides a method for treatment or prevention of cancer through novel action mechanism, namely, through inhibition of a riboflavin pathway. The method for treatment or prevention of cancer comprises administering an RF pathway inhibitor to a subject in need thereof.

Abstract: An emboss roller is provided that can give projecting-and-recess embosses to a surface sheet while uniform fiber density is realized through in an emboss roller which has a first emboss roll and a second roll formed as a set and gives projecting-and-recessed embosses by passing a surface sheet between these emboss rolls, and on the surface of the first emboss roll, a projecting portion projecting outward from a reference surface with the reference surface as a boundary and a recess portion recessed from the reference surface are provided, and the smooth reference surface is present in the periphery of the projecting portion and the recess portion, and on the surface of the second emboss roll, a projecting portion projecting outward from the reference surface with the reference surface as a boundary and meshed with the recess portion of the first emboss roll and a recess position recessed from the reference surface and meshed with the projecting portion of the first emboss roll are provided, and the smooth ref

Abstract: When securing a frame (7) made of a rigid member for carrying a heavy object such as a drive unit (3) for a walking assistance device on the hip of a wearer, a hip protective belt (4) made of fabric is wrapped around the hip of the wearer, and the frame (7) is secured thereon via a flexible plate (5) and a pressure plate (6) located on an outer side of the flexible plate (5) and having a higher rigidity than the flexible plate (5). The intermediate members allow the wearer to feel the rigidity of the frame in a mitigated manner, and the wearer would not experience any discomfort from the pressure of the frame even when the posture of the wearer is changed. The hip protective belt can readily conform to the body contour of the wearer, but the frame would not deform. Because the intermediate members absorb the difference in the builds of different wearers, the frame may come in a small number of different sizes to fit almost any wearer allowing the hip support member can be mass produced at low cost.

Abstract: An emboss roller is provided that can give projecting-and-recess embosses to a surface sheet while uniform fiber density is realized through in an emboss roller which has a first emboss roll and a second roll formed as a set and gives projecting-and-recessed embosses by passing a surface sheet between these emboss rolls, and on the surface of the first emboss roll, a projecting portion projecting outward from a reference surface with the reference surface as a boundary and a recess portion recessed from the reference surface are provided, and the smooth reference surface is present in the periphery of the projecting portion and the recess portion, and on the surface of the second emboss roll, a projecting portion projecting outward from the reference surface with the reference surface as a boundary and meshed with the recess portion of the first emboss roll and a recess position recessed from the reference surface and meshed with the projecting portion of the first emboss roll are provided, and the smooth ref

Abstract: In order to provide a walking assistance device that can avoid hampering the motion of the muscles of the user and will not move out of place inadvertently when worn by the user, principal engagement points of a support member for securely mounting an assisting force generator, which is disposed on a side of at least one joint of a lower limb to provide an assisting force to a movement of the lower limb, are provided at portions where a relatively small amount of movement of skin occurs when a trunk or joint is moved. In this way, the support member can be fastened firmly to the portions where an amount of movement of the skin is small and therefore it is possible to reduce the uncomfortable pressure caused during motion while preventing the support member from inadvertently moving out of place.

Abstract: In order to provide a walking assistance device capable of favorably providing an assisting force for maintaining the upright posture while reducing the sense of pressure when worn by the user, a hip support member (1) of the walking assisting device, which comprises an assisting force generator (hip joint actuator 10) disposed at least on a side of a hip joint to provide an assisting force to a movement of a lower limb, is provided with: a back support (4) equipped with pads (18, 19, 20) for respectively abutting an intermediate portion between right and left erector spinae muscles, lateral outer sides of the spinae muscles and right and left iliac crests; and a belt (5) connected to the back support for tightening a lower part of the rectus abdominis muscle. In this way, a supporting force can be provided to the lumbar vertebrae to steadily keep the upright posture while reducing a resistance to a bending movement of the waist caused by the support member.

Abstract: A pants garment has a pair of thigh leg members for covering the thigh area of a wearer. A front thigh elastic band member is provided substantially at a front side of each of the thigh leg members and extends obliquely from an upper front portion to a lower front portion of each thigh leg member. A back thigh elastic band member is provided substantially at a back side of each of the thigh leg members and extends obliquely from an upper back portion to a lower back portion of each thigh leg member. The garment also has a front and back crus elastic band members extending obliquely on crus leg members, which cover the crus areas of the wearer.

Abstract: A pants garment has a pair of thigh leg members for covering the thigh area of a wearer. A front thigh elastic band member is provided substantially at a front side of each of the thigh leg members and extends obliquely from an upper front portion to a lower front portion of each thigh leg member. A back thigh elastic band member is provided substantially at a back side of each of the thigh leg members and extends obliquely from an upper back portion to a lower back portion of each thigh leg member. The garment also has a front and back crus elastic band members extending obliquely on crus leg members, which cover the crus areas of the wearer.

Abstract: Provided is a femoral support member (3) for a walking assistance device that includes a power actuator (actuator 4) having a drive shaft and secured to a hip region of a wearer, the femoral support member securing a free end of an assist force transmitting arm (5) extending from the drive shaft of the power actuator to a femoral region (T) of the wearer. The femoral support member engages the femoral part of the wearer via an air pad (27) filled with air. Thus, owing to the air cushioning action of the aid pad, the air pad can readily deform itself by a large displacement even when the wearer squats and the femoral region expands. By appropriately adjusting the air in the air pad, the femoral support member can be worn by a wearer in a highly favorable manner.

Abstract: A body fluid absorbing article, which is improved in the spot absorptivity and in the diffusivity in an absorbent, and which is improved in the characteristics of a body fluid migration to the absorbent. The body fluid absorbing article comprises an absorbent sandwiched between a body fluid permeable surface member and a body fluid impermeable back member. Said absorbent includes an upper layer and a lower layer sequentially from the side of said body fluid permeable surface member, and said lower layer has a higher density than that of said upper layer.

Abstract: When securing a frame (7) made of a rigid member for carrying a heavy object such as a drive unit (3) for a walking assistance device on the hip of a wearer, a hip protective belt (4) made of fabric is wrapped around the hip of the wearer, and the frame (7) is secured thereon via a flexible plate (5) and a pressure plate (6) located on an outer side of the flexible plate (5) and having a higher rigidity than the flexible plate (5). The intermediate members allow the wearer to feel the rigidity of the frame in a mitigated manner, and the wearer would not experience any discomfort from the pressure of the frame even when the posture of the wearer is changed. The hip protective belt can readily conform to the body contour of the wearer, but the frame would not deform. Because the intermediate members absorb the difference in the builds of different wearers, the frame may come in a small number of different sizes to fit almost any wearer. Thereby, the hip support member can be mass produced at low cost.

Abstract: In a femoral support member 3 for a walking assistance device, the walking assistance device includes a power actuator (actuator 4) having a drive shaft and secured to a hip region of a wearer, and the femoral support member secures a free end of an assist force transmitting arm 5 extending from the drive shaft of the power actuator to a femoral region of the wearer. The present invention is characterized in that the femoral support member engages the femoral region of the wearer via a pad 23 provided with friction reducing means. The fact that the femoral region of the wearer is allowed to make a sliding contact with the femoral support member accommodates the relative movement between the support member and body owing to the disagreement between the axis of body movement (center of an articulate joint) and the point at which the power actuator/power transmitting arm engages the wearer's body. Therefore, the present invention is highly effective in minimizing the discomfort to the wearer.

Abstract: A leg support garment of a tights type that has stretchability and is applied in close contact with the human body so as to support the legs is provided with a stretchable part having a relatively great straining force. The stretchable part having a relatively great straining force includes a stretchable portion (A) having a relatively great straining force that substantially covers the ligamentum collateralle on a medial side of the knee joint of the human body, and on a superior side of the knee joint, extends through a length of not less than ¼ of that of the thigh, along at least one selected from the musculus group consisting of the musculus sartorius, the musculus semitendinosus, the musculus semimembranosus, and the musculus gracilis.

Abstract: A leg support garment of a tights type that has stretchability and is applied in close contact with the human body so as to support the legs is provided with a stretchable part having a relatively great straining force. The stretchable part having a relatively great straining force includes a stretchable portion (A) having a relatively great straining force that substantially covers the ligamentum collateralle on a medial side of the knee joint of the human body, and on a superior side of the knee joint, extends through a length of not less than ¼ of that of the thigh, along at least one selected from the musculus group consisting of the musculus sartorius, the musculus semitendinosus, the musculus semimembranosus, and the musculus gracilis.

Abstract: In order to provide a walking assistance device that can avoid hampering the motion of the muscles of the user and will not move out of place inadvertently when worn by the user, principal engagement points of a support member (hip support member 1 and/or lower leg support member 2) for securely mounting an assisting force generator (hip joint actuator 10 and/or knee joint actuator 26), which is disposed on a side of at least one joint of a lower limb to provide an assisting force to a movement of the lower limb, are provided at portions where a relatively small amount of movement of skin occurs when a trunk or joint is moved. In this way, the support member can be fastened firmly to the portions where an amount of movement of the skin is small, i.e.

Abstract: A garment comprising a stretch fabric wherein the garment covers at least a part of the lower body of a wearer, has a crotch part, and is worn by being fitted to the wearer's body, wherein the garment in part has a first portion with a strong straining force; first portion with a strong straining force is a strong straining portion (A); right and left parts of the portion (A) are connected at a second position on the back side of the garment corresponding to any region from os sacrum to vertebrae lumbalis of the wearer's body; and the portion (A) covers a region extending from second position through tops of bulges of the buttocks or vicinities thereof approximately in the direction of muscle fibers of musculus gluteus maximus at right and left to at least the vicinity of trochanter major.

Abstract: A pants garment has a pair of thigh leg members for covering the thigh area of a wearer. A front thigh elastic band member is provided substantially at a front side of each of the thigh leg members and extends obliquely from an upper front portion to a lower front portion of each thigh leg member. A back thigh elastic band member is provided substantially at a back side of each of the thigh leg members and extends obliquely from an upper back portion to a lower back portion of each thigh leg member. The garment also has a front and back crus elastic band members extending obliquely on crus leg members, which cover the crus areas of the wearer.

Abstract: A body fluid absorbing article, which is improved in the spot absorptivity and in the diffusivity in an absorbent, and which is improved in the characteristics of a body fluid migration to the absorbent. The body fluid absorbing article comprises an absorbent sandwiched between a body fluid permeable surface member and a body fluid impermeable back member. Said absorbent includes an upper layer and a lower layer sequentially from the side of said body fluid permeable surface member, and said lower layer has a higher density than that of said upper layer.

Abstract: A leg support garment of a tights type that has stretchability and is applied in close contact with the human body so as to support the legs is provided with a stretchable part having a relatively great straining force. The stretchable part having a relatively great straining force includes a stretchable portion (A) having a relatively great straining force that substantially covers the ligamentum collateralle on a medial side of the knee joint of the human body, and on a superior side of the knee joint, extends through a length of not less than ¼ of that of the thigh, along at least one selected from the musculus group consisting of the musculus sartorius, the musculus semitendinosus, the musculus semimembranosus, and the musculus gracilis.