Patents by Inventor Takako Iwasaki

Takako Iwasaki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tricyclic benzazepine compounds
    Patent number: 6093714
    Abstract: Tricyclic benzazepine compounds represented by the following formula (I) and pharmacologically acceptable salts thereof are disclosed. These compounds have antiallergic activity and are useful for treatment and prevention of bronchial asthma, eczema, hives, allergic gastrointestinal troubles, allergic rhinitis, allergic conjunctivitis, etc. wherein R represents a hydrogen atom, substituted C.sub.1-6 alkyl or a protective group and R.sup.1, R.sup.2, R.sup.3, and R.sup.4 represent a hydrogen atom, a hydroxyl group, substituted C.sub.1-4 alkyl, substituted C.sub.2-12 alkenyl, substituted C.sub.1-12 alkoxy, or substituted amino.
    Type: Grant
    Filed: June 17, 1998
    Date of Patent: July 25, 2000
    Assignee: Meiji Seika Kaisha, Ltd.
    Inventors: Yasuo Ohtsuka, Toshio Nishizuka, Sohjiro Shiokawa, Seiji Tsutsumi, Kenichi Fusihara, Mami Kawaguchi, Megumi Imai, Keiko Shito, Koji Tsuchiya, Takako Iwasaki, Hiroko Ogino, Takashi Shishikura
  • Triazole intermediates for tricyclic benzazepine and benzothiazepine derivatives
    Patent number: 5840895
    Abstract: Compounds of formulae (II), (III), (IV) and (V) or salts thereof are intermediates for pharmacologically active tricyclic benzazepine and benzothiazepine derivatives, ##STR1## wherein R represents hydrogen, alkyl, phenylalkyl, or a protective group of a triazole ring, R.sup.1 -R.sup.5 represent hydrogen, alkyl, alkenyl, alkoxy, amino, oxim or hydroxyl, and R.sup.41 represents hydrogen, C.sub.1-6 alkyl which may be optionally substituted, or a protective group for a carboxyl group.
    Type: Grant
    Filed: June 26, 1997
    Date of Patent: November 24, 1998
    Assignee: Meiji Seika Kabushiki Kaisha
    Inventors: Yasuo Ohtsuka, Takashi Shishikura, Hiroko Ogino, Kenichi Fushihara, Mami Kawaguchi, Seiji Tsutsumi, Megumi Imai, Keiko Shito, Koji Tsuchiya, Junko Tanaka, Takako Iwasaki, Shigeru Hoshiko, Takashi Tsuruoka
  • Tricyclic benzazepine and benzothiazepine derivatives
    Patent number: 5686442
    Abstract: The tricyclic benzazepine and benzothiazepine derivatives represented by the formula (I) and pharmacologically acceptable salts thereof are disclosed. ##STR1## wherein Z represents CO, --CR.sup.6 R.sup.7 -- or --S(O).sub.n, R represents hydrogen, alkyl, phenylalkyl, or a protective group of a triazole ring, R.sup.1 -R.sup.5 represent hydrogen, alkyl, alkenyl, alkoxy, amino, oxim or hydroxyl. These compounds have anti-allergic effect and are useful for the treatment and prophylaxis of allergic diseases.
    Type: Grant
    Filed: October 26, 1995
    Date of Patent: November 11, 1997
    Assignee: Meiji Seika Kabushiki Kaisha
    Inventors: Yasuo Ohtsuka, Takashi Shishikura, Hiroko Ogino, Kenichi Fushihara, Mami Kawaguchi, Seiji Tsutsumi, Megumi Imai, Keiko Shito, Koji Tsuchiya, Junko Tanaka, Takako Iwasaki, Shigeru Hoshiko, Takashi Tsuruoka