Patents by Inventor Takamasa Sakai

Takamasa Sakai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230330304
    Abstract: To provide a method for suppressing the entry of scar tissue in the treatment of a tendon or ligament, promoting healing by intratendinous cells, and efficiently restoring the original function of the tendon. A gel material including a polymer gel for suppressing expression of type III collagen in the treatment of an injured or ruptured tendon or ligament, in which the polymer gel is a hydrogel having a three-dimensional network structure formed by crosslinking of hydrophilic polymers, and has a polymer content of from 1 to 5% by weight and an elastic modulus of from 100 to 10000 Pa.
    Type: Application
    Filed: July 13, 2021
    Publication date: October 19, 2023
    Inventors: Takamasa SAKAI, Taku SAITO, Yasuhide IWANAGA, Sakae TANAKA, Kosuke MASUI, Shinichi NARITA
  • Publication number: 20230293778
    Abstract: An object of the present invention is to provide a novel use in which a polymer gel material having a µm-scale porous structure can be suitably used. A gel material for regenerative medicine comprising a polymer gel in which hydrophilic polymer units are crosslinked with each other, wherein the polymer gel contains water as a solvent and has a three-dimensional network structure having two regions: a first region in which the polymer units are densely present and a second region in which the polymer units are sparsely present, and a mesh size composed of the first region is the range of 1 to 500 µm.
    Type: Application
    Filed: January 25, 2021
    Publication date: September 21, 2023
    Inventors: Takamasa SAKAI, Hironori HOJO, Shoichiro TANI, Kosuke MASUI, Shinichi NARITA
  • Publication number: 20230218797
    Abstract: An object of the present invention is to provide a hemostatic method, a vascular occlusion method, a tissue covering method, and a body fluid coagulation method that are safe and efficient using a polymer material that is a non-biologically derived synthetic product. A solution (pre-gel solution) is prepared that contains, under a specific concentration condition, a hydrophilic polymer capable of forming a hydrogel by intermolecular crosslinking and has a specific pH condition and specific ionic strength, and the solution is gelled in situ in an environment, such as a bleeding site or the interior of a blood vessel, where blood is present.
    Type: Application
    Filed: May 6, 2021
    Publication date: July 13, 2023
    Inventors: Takamasa SAKAI, Kosuke MASUI, Shinichi NARITA, Hiroyuki KAMATA
  • Publication number: 20210155799
    Abstract: An object of the present invention is to provide a gel material including a solvophilic polymer having a ?m-scale porous structure. A polymer gel in which solvophilic polymer units are cross-linked with each other, wherein the polymer gel contains a solvent and has a three-dimensional network structure having two regions: a first region in which the polymer units are densely present and a second region in which the polymer units are sparsely present, and a mesh size composed of the first region is from 1 to 500 ?m.
    Type: Application
    Filed: July 29, 2019
    Publication date: May 27, 2021
    Inventors: Takamasa SAKAI, Yuichi TEI
  • Publication number: 20200299638
    Abstract: Provided is a liquid set for a droplet discharging apparatus, the liquid set including: Liquid A containing a multi-branched polymer A, the polymer containing, as a backbone, a polyethylene glycol containing at least three branches, the branches containing one or more electrophilic functional groups in at least one of a side chain(s) and an end(s); and Liquid B containing a multi-branched polymer B, the polymer containing, as a backbone, a polyethylene glycol containing at least three branches, the branches containing one or more nucleophilic functional groups in at least one of a side chain(s) and an end(s); the Liquid A and the Liquid B each having a pH of from 5 to 10, and containing the multi-branched polymer at a concentration of from 0.3% by mass to 20% by mass.
    Type: Application
    Filed: March 19, 2020
    Publication date: September 24, 2020
    Inventors: Momoko Shionoiri, Hidekazu Yaginuma, Chihiro Kubo, Takamasa Sakai
  • Patent number: 10550225
    Abstract: [Problem] To provide a gel which can be produced in a short time, has controlled properties such as modulus and expansion pressure, and has a low polymer concentration. [Solution] A process for producing a polymer gel in which gel-precursor clusters have been crosslinked with one another to form a three-dimensional network structure, characterized by comprising a) a step in which monomer or polymer units that are present in a concentration less than a critical gelation concentration are crosslinked to form the gel-precursor clusters, the gel-precursor clusters having a storage modulus G? and a loss modulus G? which satisfy the relationship G?<G?, and b) a step in which the gel-precursor clusters are crosslinked with one another by a crosslinking agent to obtain a gel having a three-dimensional network structure.
    Type: Grant
    Filed: March 3, 2016
    Date of Patent: February 4, 2020
    Assignee: The University of Tokyo
    Inventors: Takamasa Sakai, Yuichi Tei
  • Publication number: 20190015559
    Abstract: Provided is a gel material for ophthalmic treatment useful as a synthetic vitreous body which is a novel intraocular tamponade material having a low swelling pressure, an appropriate elastic force, and no toxicity to ocular tissues, specifically, to retinas, and which is capable of stably maintaining a long-term stable tamponade effect. A gel material for ophthalmic treatment including a hydrogel in which a gel precursor cluster crosslinks to form a three-dimensional network. The gel precursor cluster has a structure with crosslinked monomer units or crosslinked polymer units present at concentrations less than a critical gelation concentration, and the gel precursor cluster has a relationship of G?<G? where G? represents a storage elastic modulus and G? represents a loss elastic modulus. The hydrogel has a polymer content of 50 g/L or less, a storage elastic modulus G? of 1 to 10,000 Pa at a frequency of 1 Hz, and a fractal dimension of 1.5 to 2.5.
    Type: Application
    Filed: December 21, 2016
    Publication date: January 17, 2019
    Applicants: The University of Tokyo, University of Tsukuba
    Inventors: Takamasa SAKAI, Yuichi TEI, Fumiki OKAMOTO, Sujin HOSHI
  • Publication number: 20180030205
    Abstract: [Problem] To provide a gel which can be produced in a short time, has controlled properties such as modulus and expansion pressure, and has a low polymer concentration. [Solution] A process for producing a polymer gel in which gel-precursor clusters have been crosslinked with one another to form a three-dimensional network structure, characterized by comprising a) a step in which monomer or polymer units that are present in a concentration less than a critical gelation concentration are crosslinked to form the gel-precursor clusters, the gel-precursor clusters having a storage modulus G? and a loss modulus G? which satisfy the relationship G?<G?, and b) a step in which the gel-precursor clusters are crosslinked with one another by a crosslinking agent to obtain a gel having a three-dimensional network structure.
    Type: Application
    Filed: March 3, 2016
    Publication date: February 1, 2018
    Inventors: Takamasa SAKAI, Yuichi TEI
  • Publication number: 20120133042
    Abstract: A mounting structure of chip comprises a substrate having a base, a chip on the upper surface of the base, and adhesive agents which bonds the base and the first chip. The adhesive agent is applied to the upper surface of the base. The chip has a rectangular shape to have a width and a length, and is bonded at its lower surface to the base. The adhesive agents comprises the first adhesive agent, the second adhesive agent, and the third adhesive agent which are disposed on the three spots of the upper surface of the base, respectively. The three spots on the base are located on vertexes of a triangle. The first chip is bonded to the base by only the first adhesive agent, the second adhesive agent, and the third adhesive agent.
    Type: Application
    Filed: May 21, 2009
    Publication date: May 31, 2012
    Applicant: Panasonic Electric Works Co., Ltd.
    Inventors: Shintarou Hayashi, Mitsuhiko Ueda, Yoshiharu Sanagawa, Takamasa Sakai
  • Publication number: 20120122949
    Abstract: [Problem] The present invention is intended to provide high-strength hydrogels and method for fabricating the same. The present invention is intended to provide the method for fabricating the hydrogels with different decomposition rates. [Solution to Problem] The present invention is based on a knowledge that high-strength hydrogels can be fabricated by controlling pH of solution, ionic strength in the solution, and buffer concentration in the solution. In addition, the present invention is based on a knowledge that the high-strength hydrogels which have homogeneous macromolecular network structure can be fabricated by polymerizing four-branching compounds after having dispersed the four-branching compounds homogeneously.
    Type: Application
    Filed: June 19, 2009
    Publication date: May 17, 2012
    Applicants: THE UNIVERSITY OF TOKYO, NEXT21 K.K.
    Inventors: Yuichi Tei, Takamasa Sakai, Nobuo Sasaki, Mitsuhiro Shibayama, Shigeki Suzuki
  • Patent number: 7869062
    Abstract: In a substrate supporting apparatus of a surface potential measuring apparatus, a first fluid is ejected around a target region on an upper surface of a substrate from a circular-shaped first porous member of a first fluid ejection part and a second fluid is ejected onto a lower surface of the substrate from a circular-shaped second porous member of a second fluid ejection part which is opposite to the first fluid ejection part. The substrate can be supported and flattened between the first fluid ejection part and the second fluid ejection part. Also, it is possible to keep the distance between the substrate and the first porous member, with a simple construction. As a result, a probe can be positioned above a flatted target region with leaving a predetermined spacing, to perform measurement of a surface potential of the target region on the substrate with high accuracy.
    Type: Grant
    Filed: January 9, 2008
    Date of Patent: January 11, 2011
    Assignee: Dainippon Screen MFG Co., Ltd.
    Inventors: Yoshiyuki Nakazawa, Takamasa Sakai
  • Patent number: 7539097
    Abstract: An optical disk device is provided with a first analog-to-digital converter for converting a push-pull signal detected from an optical disc medium into a digital sampling signal according to a sampling clock in the vicinity of a channel frequency. The optical disk device also includes an address polarity information detection circuit for detecting address polarity information from the digital sampling signal, and an address position information detection circuit for detecting address position information from the digital sampling signal while maintaining continuity.
    Type: Grant
    Filed: September 26, 2005
    Date of Patent: May 26, 2009
    Assignee: Panasonic Corporation
    Inventors: Youichi Ogura, Toshihiko Takahashi, Teruhiko Izumi, Shinichi Konishi, Hironori Deguchi, Takamasa Sakai
  • Publication number: 20080174637
    Abstract: In a substrate supporting apparatus of a surface potential measuring apparatus, a first fluid is ejected around a target region on an upper surface of a substrate from a circular-shaped first porous member of a first fluid ejection part and a second fluid is ejected onto a lower surface of the substrate from a circular-shaped second porous member of a second fluid ejection part which is opposite to the first fluid ejection part. The substrate can be supported and flattened between the first fluid ejection part and the second fluid ejection part. Also, it is possible to keep the distance between the substrate and the first porous member, with a simple construction. As a result, a probe can be positioned above a flatted target region with leaving a predetermined spacing, to perform measurement of a surface potential of the target region on the substrate with high accuracy.
    Type: Application
    Filed: January 9, 2008
    Publication date: July 24, 2008
    Inventors: Yoshiyuki Nakazawa, Takamasa Sakai
  • Patent number: 7190643
    Abstract: In a land pre-pit address demodulating device DM for detecting land pre-pit address information during recording to a DVD-R/RW-disc, a tracking error signal TE is muted by a first reference potential Vref1 during a period in which the tracking error signal TE is generated from a reflected laser beam having a power for recording a mark, an RF residual component is removed from the tracking error signal TE, and the tracking error signal TE from which the RF residual component has been removed is compared with a second reference potential Vref2, thereby detecting a land pre-pit address signal.
    Type: Grant
    Filed: May 4, 2004
    Date of Patent: March 13, 2007
    Assignee: Matsushita Electric Industrial Co., Ltd.
    Inventors: Akihiro Shibata, Dai Ichiryu, Takamasa Sakai
  • Publication number: 20060191556
    Abstract: In a substrate processing apparatus (1), a ring-shaped cover part (61) opposed to an annular surface (51a) of a rotating part (51) is provided and the rotating part (51) rotates the substrate (9) while holding the substrate (9). An exhaust flow space (64) connecting with a gap space (62) between the cover part (61) and the annular surface (51a) along an outer edge of the cover part (61) is formed by a duct main body (63) connected to the cover part (61) along the outer edge of the cover part (61). Since a cross-sectional area of the exhaust flow space (64) increases gradually along a rotation direction of the rotating part (51), it is possible to reduce variation of inlet flow speed of air around the gap space (62) and to suppress nonuniformity of processing of the substrate (9).
    Type: Application
    Filed: February 23, 2006
    Publication date: August 31, 2006
    Inventors: Yoshiyuki Nakazawa, Sadao Hirae, Takamasa Sakai
  • Patent number: 7073521
    Abstract: In a substrate processing apparatus for performing a substrate processing with a substrate being rotated, a ring-shaped motor is provided and a water pipe, a drainpipe and gas supply pipes are connected to a stationary part of the motor covered with a rotating part thereof. A gas from the gas supply pipes is supplied between the stationary part and the rotating part of the motor, thereby making the rotating part rotatable with a mechanism of a static pressure gaseous bearing (and a mechanical rotary). A group of induction coils are provided in a ring shape, and the water pipe and the drainpipe are connected to a duct for cooling water formed in the stationary part along the group of induction coils. This constitution allows removal of heat generated by the group of induction coils, to thereby achieving an adequate high-speed rotation of the substrate.
    Type: Grant
    Filed: September 10, 2002
    Date of Patent: July 11, 2006
    Assignee: Dainippon Screen Mfg. Co., Ltd.
    Inventor: Takamasa Sakai
  • Publication number: 20060077828
    Abstract: An optical disk device is provided with a first analog-to-digital converter for converting a push-pull signal detected from an optical disc medium into a digital sampling signal according to a sampling clock in the vicinity of a channel frequency, an address polarity information detection circuit for detecting address polarity information from the digital sampling signal, and an address position information detection circuit 58 for detecting address position information from the digital sapling signal while maintaining continuity. Therefore, it is possible to detect the address polarity information and the address position information stably and accurately even during high-speed recording/playback.
    Type: Application
    Filed: September 26, 2005
    Publication date: April 13, 2006
    Inventors: Youichi Ogura, Toshihiko Takahashi, Teruhiko Izumi, Shinichi Konishi, Hironori Deguchi, Takamasa Sakai
  • Publication number: 20050078572
    Abstract: In a land pre-pit address demodulating device DM for detecting land pre-pit address information during recording to a DVD-R/RW-disc, a tracking error signal TE is muted by a first reference potential Vref1 during a period in which the tracking error signal TE is generated from a reflected laser beam having a power for recording a mark, an RF residual component is removed from the tracking error signal TE, and the tracking error signal TE from which the RF residual component has been removed is compared with a second reference potential Vref2, thereby detecting a land pre-pit address signal.
    Type: Application
    Filed: May 4, 2004
    Publication date: April 14, 2005
    Inventors: Akihiro Shibata, Dai Ichiryu, Takamasa Sakai
  • Patent number: 6598805
    Abstract: A gas mixture of dry steam and nitrogen gas serving as carrier gas is blown into a hot water mist injection port for rendering the nitrogen gas serve as a medium absorbing latent heat of condensation, thereby smoothly progressing condensation of water vapor and efficiently forming hot water mist. The water vapor is condensed in the hot water mist injection port formed by a cylindrical pipe for supplying latent heat of condensation to the nitrogen gas and dilating the same, thereby accelerating the flow of the hot water mist and spraying the hot water mist to a substrate from the hot water mist injection port at a high speed. Small droplets contained in the high-speed hot water mist have high kinetic energy and high thermal energy, for exhibiting a large colliding effect and a high activation effect with respect to small contaminants adhering to the substrate. A substrate cleaning apparatus capable of spraying hot water mist attaining a high cleaning effect to a substrate is provided.
    Type: Grant
    Filed: May 15, 2002
    Date of Patent: July 29, 2003
    Assignee: Dainippon Screen Mfg. Co., LTD
    Inventors: Takamasa Sakai, Sadao Hirae
  • Publication number: 20030056815
    Abstract: In a substrate processing apparatus for performing a substrate processing with a substrate being rotated, a ring-shaped motor is provided and a water pipe, a drainpipe and gas supply pipes are connected to a stationary part of the motor covered with a rotating part thereof. A gas from the gas supply pipes is supplied between the stationary part and the rotating part of the motor, thereby making the rotating part rotatable with a mechanism of a static pressure gaseous bearing (and a mechanical rotary). A group of induction coils are provided in a ring shape, and the water pipe and the drainpipe are connected to a duct for cooling water formed in the stationary part along the group of induction coils. This constitution allows removal of heat generated by the group of induction coils, to thereby achieving an adequate high-speed rotation of the substrate.
    Type: Application
    Filed: September 10, 2002
    Publication date: March 27, 2003
    Applicant: Dainippon Screen Mfg. Co, Ltd.
    Inventor: Takamasa Sakai