Patents by Inventor Takanari Tominaga
Takanari Tominaga has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20100137228Abstract: Medicinal compositions for treating, ameliorating or preventing diseases with sensitivity to 3,6-anhydrogalactopyranose represented by formula (1): foods, drinks, cosmetics, etc. containing as the active ingredient at least one member selected from the group consisting of the above-mentioned compound, its aldehyde, its hydrate and 2-O-methylated derivatives thereof and soluble sugar compounds containing the above compound. This compound also shows, for example, an apoptosis-inducing activity, a carcinostatic activity and inhibitory activities on the production of active oxygen, lipid peroxide radicals and NO, which makes it useful also as the active ingredient of antioxidants and preservatives.Type: ApplicationFiled: August 11, 2008Publication date: June 3, 2010Applicant: TAKARA BIO INC.Inventors: Tatsuji ENOKI, Hiroaki SAGAWA, Takanari TOMINAGA, Eiji NISHIYAMA, Nobuto KOYAMA, Takeshi SAKAI, Fu-Gong YU, Katsushige IKAI, Ikunoshin KATO
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Publication number: 20100048491Abstract: Medicinal compositions for treating, ameliorating or preventing diseases with sensitivity to 3,6-anhydrogalactopyranose represented by formula (1): foods, drinks, cosmetics, etc. containing as the active ingredient at least one member selected from the group consisting of the above-mentioned compound, its aldehyde, its hydrate and 2-O-methylated derivatives thereof and soluble sugar compounds containing the above compound. This compound also shows, for example, an apoptosis-inducing activity, a carcinostatic activity and inhibitory activities on the production of active oxygen, lipid peroxide radicals and NO, which makes it useful also as the active ingredient of antioxidants and preservatives.Type: ApplicationFiled: August 11, 2008Publication date: February 25, 2010Applicant: TAKARA BIO INC.Inventors: Tatsuji ENOKI, Hiroaki SAGAWA, Takanari TOMINAGA, Eiji NISHIYAMA, Nobuto KOYAMA, Takeshi SAKAI, Fu-Gong YU, Katsushige IKAI, Ikunoshin KATO
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Publication number: 20090099101Abstract: Medicinal compositions for treating, ameliorating or preventing diseases with sensitivity to 3,6-anhydrogalactopyranose represented by formula (1): foods, drinks, cosmetics, etc. containing as the active ingredient at least one member selected from the group consisting of the above-mentioned compound, its aldehyde, its hydrate and 2-O-methylated derivatives thereof and soluble sugar compounds containing the above compound. This compound also shows, for example, an apoptosis-inducing activity, a carcinostatic activity and inhibitory activities on the production of active oxygen, lipid peroxide radicals and NO, which makes it useful also as the active ingredient of antioxidants and preservatives.Type: ApplicationFiled: August 11, 2008Publication date: April 16, 2009Applicant: Takara Shuzo Co., Ltd.Inventors: Tatsuji Enoki, Hiroaki Sagawa, Takanari Tominaga, Eiji Nishiyama, Nobuto Koyama, Takeshi Sakai, Fu-Gong Yu, Katsushige Ikai, Ikunoshin Kato
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Patent number: 7417031Abstract: Medicinal compositions for treating, ameliorating or preventing diseases with sensitivity to 3,6-anhydrogalactopyranose represented by formula (1): foods, drinks, cosmetics, etc. containing as the active ingredient at least one member selected from the group consisting of the above-mentioned compound, its aldehyde, its hydrate and 2-O-methylated derivatives thereof and soluble sugar compounds containing the above compound. This compound also shows, for example, an apoptosis-inducing activity, a carcinostatic activity and inhibitory activities on the production of active oxygen, lipid peroxide radicals and NO, which makes it useful also as the active ingredient of antioxidants and preservatives.Type: GrantFiled: January 13, 2005Date of Patent: August 26, 2008Assignee: Takara Bio Inc.Inventors: Tatsui Enoki, Hiroaki Sagawa, Takanari Tominaga, Eiji Nishiyama, Nobuto Koyama, Takeshi Sakai, Fu-Gong Yu, Katsushige Ikai, Ikunoshin Kato
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Patent number: 6911432Abstract: Medicinal compositions for treating, ameliorating or preventing diseases with sensitivity to 3,6-anhydrogalactopyranose are represented by formula (I): These compositions include foods, drinks, cosmetics, etc. containing as the active ingredient at least one such compound, its aldehyde, its hydrate and 2-O-methylated derivatives thereof and soluble sugar compounds containing the above compound. These compounds show an apoptosis-inducing activity, carcinostatic activity and inhibitory activities on the production of active oxygen, lipid peroxide radicals and NO, which makes them useful also as the active ingredient of antioxidants and preservatives.Type: GrantFiled: August 27, 2002Date of Patent: June 28, 2005Inventors: Tatsuji Enoki, Hiroaki Sagawa, Takanari Tominaga, Eiji Nishiyama, Nobuto Koyama, Takeshi Sakai, Fu-Gong Yu, Katsushige Ikai, Ikunoshin Kato
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Publication number: 20050119191Abstract: Medicinal compositions for treating, ameliorating or preventing diseases with sensitivity to 3,6-anhydrogalactopyranose represented by formula (1): foods, drinks, cosmetics, etc. containing as the active ingredient at least one member selected from the group consisting of the above-mentioned compound, its aldehyde, its hydrate and 2-O-methylated derivatives thereof and soluble sugar compounds containing the above compound. This compound also shows, for example, an apoptosis-inducing activity, a carcinostatic activity and inhibitory activities on the production of active oxygen, lipid peroxide radicals and NO, which makes it useful also as the active ingredient of antioxidants and preservatives.Type: ApplicationFiled: January 13, 2005Publication date: June 2, 2005Applicant: Takara Shuzo Co., Ltd.Inventors: Tatsui Enoki, Hiroaki Sagawa, Takanari Tominaga, Eiji Nishiyama, Nobuto Koyama, Takeshi Sakai, Fu-Gong Yu, Katsushige Ikai, Ikunoshin Kato
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Patent number: 6608032Abstract: Medicinal compositions for treating or preventing diabetes, rheumatoid, diseases wherein inflammation should be inhibited, diseases wherein &agr;-glycosidase should be inhibited, diseases wherein the synthesis of prostaglandin should be inhibited, diseases wherein endotoxin shock should be inhibited, diseases wherein the production of interleukin should be inhibited, diseases wherein the production of heme oxygenase should be induced, and diseases wherein the production of tumor necrosis factor or carcinogenesis should be inhibited, which contain as the active ingredient at least one compound selected from the group consisting of 3,6-anhydrogalactopyranose represented by formula (I), its aldehyde, its hydrate and 2-O-methylated derivatives and 2-O-sulfated derivatives thereof.Type: GrantFiled: July 20, 2001Date of Patent: August 19, 2003Assignee: Takara Shuzo Co., Ltd.Inventors: Tatsuji Enoki, Hiroaki Sagawa, Jun Tomono, Takanari Tominaga, Eiji Nishiyama, Hua-Kang Wu, Ikunoshin Kato
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Patent number: 6593311Abstract: Apoptosis inducers, anticancer drugs and carcinostatic drugs containing sulfated-fucose-containing polysaccharide(s) and/or degradation product(s) thereof, and a method for inducing apoptosis by using sulfated-fucose-containing polysaccharide(s) and/or degradation product(s) thereof as the active ingredient. A degrading enzyme which is useful in the production of the degradation products of sulfated-fucose-containing polysaccharides.Type: GrantFiled: January 29, 2001Date of Patent: July 15, 2003Assignees: Takara Shuzo Co., Ltd., Research Institute for GlycotechnologyInventors: Takeshi Sakai, Hideo Kitano, Fu-Gong Yu, Shinji Nakayama, Kaoru Kojima, Hitomi Kimura, Yoshikuni Nakanishi, Kaoru Katayama, Takanari Tominaga, Kazuo Shimanaka, Katsushige Ikai, Ikunoshin Kato
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Publication number: 20030105029Abstract: Medicinal compositions for treating, ameliorating or preventing diseases with sensitivity to 3,6-anhydrogalactopyranose are represented by formula (I): 1Type: ApplicationFiled: August 27, 2002Publication date: June 5, 2003Applicant: TAKARA SHUZO CO., LTD.Inventors: Tatsuji Enoki, Hiroaki Sagawa, Takanari Tominaga, Eiji Nishiyama, Nobuto Koyama, Takeshi Sakai, Fu-Gong Yu, Katsushige Ikai, Ikunoshin Kato
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Patent number: 6548543Abstract: Remedies or preventives for diseases with a need for immunoregulation, diseases with a need for inhibition of inflammation, diseases with a need for regulation of tumor necrosis factor production, diseases with a need for regulation of fungal growth, diseases with a need for regulation of cell adhesion or disease with a deed for induction of heat-shock protein, which contain as the active ingredient at least one compound selected from among cyclopentenone derivatives represented by general formula [I], optically active isomers and salts thereof, wherein R1 and R2 are the same or different and each represents hydrogen, an aliphatic group, an aromatic group or an aromatic aliphatic group.Type: GrantFiled: February 20, 2001Date of Patent: April 15, 2003Assignee: Takara Shuzo Co., Ltd.Inventors: Eiji Kobayashi, Hiromu Ohnogi, Hiroaki Sagawa, Takanari Tominaga, Eiji Nishiyama, Nobuto Koyama, Katsushige Ikai, Ikunoshin Kato
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Patent number: 6518302Abstract: Compounds represented by general formula (I) wherein X represents OH or OSO3H; and R represents a substituent other than OH which allows, after leaving, the induction of unsaturated bonds into the 3- and 4-positions of 3,6-anhydrogalactose or its sulfated derivative, and/or a substituent showing a tissue-specific affinity.Type: GrantFiled: July 20, 2001Date of Patent: February 11, 2003Assignee: Takara Shuzo Co., Ltd.Inventors: Eiji Kobayashi, Tuo-Ping Li, Tatsuji Enoki, Takanari Tominaga, Hiroaki Sagawa, Ikunoshin Kato
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Patent number: 6475990Abstract: Medicinal compositions for treating, ameliorating or preventing diseases with sensitivity to 3,6-anhydrogalactopyranose represented by formula (1): foods, drinks, cosmetics, etc. containing as the active ingredient at least one member selected from the group consisting of the above-mentioned compound, its aldehyde, its hydrate and 2-O-methylated derivatives thereof and soluble sugar compounds containing the above compound. This compound also shows, for example, an apoptosis-inducing activity, a carcinostatic activity and inhibitory activities on the production of active oxygen, lipid peroxide radicals and NO, which makes it useful also as the active ingredient of antioxidants and preservatives.Type: GrantFiled: May 11, 2000Date of Patent: November 5, 2002Assignee: Takara Shuzo Co., Ltd.Inventors: Tatsuji Enoki, Hiroaki Sagawa, Takanari Tominaga, Eiji Nishiyama, Nobuto Koyama, Takeshi Sakai, Fu-Gong Yu, Katsushige Ikai, Ikunoshin Kato
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Publication number: 20010034335Abstract: Apoptosis inducers, anticancer drugs and carcinostatic drugs containing sulfated-fucose-containing polysaccharide(s) and/or degradation product(s) thereof, and a method for inducing apoptosis by using sulfated-fucose-containing polysaccharide(s) and/or degradation product(s) thereof as the active ingredient. A degrading enzyme which is useful in the production of the degradation products of sulfated-fucose-containing polysaccharides.Type: ApplicationFiled: January 29, 2001Publication date: October 25, 2001Inventors: Takeshi Sakai, Hideo Kitano, Fu-Gong Yu, Shinji Nakayama, Kaoru Kojima, Hitomi Kimura, Yoshikuni Nakanishi, Kaoru Katayama, Takanari Tominaga, Kazuo Shimanaka, Katsushige Ikai, Ikunoshin Kato
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Patent number: 6284801Abstract: An antirheumatic agent which is characterized in containing at least one compound selected from a group consisting of 4,5-dihydroxy-2-cyclopenten-l-one represented by the following formula [I] and an optically active substance and a salt thereof as an effective component.Type: GrantFiled: August 27, 1999Date of Patent: September 4, 2001Assignee: Takara Shuzo Co., Ltd.Inventors: Nobuto Koyama, Hua-Kang Wu, Takanari Tominaga, Eiji Nishiyama, Michio Hagiya, Tatsuji Enoki, Hiromu Ohnogi, Ikunoshin Kato
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Patent number: 6228892Abstract: An antiallergic agent which is characterized in containing at least one compound selected from a group consisting of 4,5-dihydroxy-2-cyclopenten-1-one represented by the following formula [I] and an optically active substance and a salt thereof as an effective component.Type: GrantFiled: November 15, 1999Date of Patent: May 8, 2001Assignee: Takara Shuzo Co., Ltd.Inventors: Takanari Tominaga, Eiji Nishiyama, Michio Hagiya, Nobuto Koyama, Ikunoshin Kato
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Patent number: 6207652Abstract: Apoptosis inducers, anticancer drugs and carcinostatic drugs containing sulfated-fucose-containing polysaccharide(s) and/or degradation product(s) thereof, and a method for inducing apoptosis by using sulfated-fucose-containing polysaccharide(s) and/or degradation product(s) thereof as the active ingredient. A degrading enzyme which is useful in the production of the degradation products of sulfated-fucose-containing polysaccharides.Type: GrantFiled: April 9, 1998Date of Patent: March 27, 2001Assignees: Takara Shuzo Co., Ltd., Research Institute for GlycotechnologyInventors: Takeshi Sakai, Hideo Kitano, Fu-Gong Yu, Shinji Nakayama, Kaoru Kojima, Hitomi Kimura, Yoshikuni Nakanishi, Kaoru Katayama, Takanari Tominaga, Kazuo Shimanaka, Katsushige Ikai, Ikunoshin Kato
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Patent number: 6194467Abstract: A therapeutic or preventive agent for diabetes mellitus which is characterized in containing at least one compound selected from a group consisting of 4,5-dihydroxy-2-cyclopenten-1-one represented by the following formula [I] and an optically active substance and a salt thereof as an effective component.Type: GrantFiled: August 9, 1999Date of Patent: February 27, 2001Assignee: Takara Shuzo Co., Ltd.Inventors: Hua-Kang Wu, Nobuto Koyama, Eiji Nishiyama, Takanari Tominaga, Michio Hagiya, Ikunoshin Kato
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Patent number: 6177592Abstract: A compound represented by the following formula [I] or an optically active substance or a salt thereof. (In the formula, a bond shown by a dotted line in the five-membered ring means that said five-membered ring may be any of a cyclopentene ring having a double bond and a cyclopentane ring where said bond is saturated and, in the case of a cyclopentene ring, X is OH, Y is ═O and Z is H while, in the case of a cyclopentane ring, X is ═O, Y is OH and Z is OH. R is a residue after removal of an SH group from the SH-containing compound.Type: GrantFiled: July 16, 1999Date of Patent: January 23, 2001Assignee: Takara Shuzo Co., Ltd.Inventors: Nobuto Koyama, Tatsuji Enoki, Katsushige Ikai, Hua-Kang Wu, Hiromu Ohnogi, Takanari Tominaga, Eiji Nishiyama, Michio Hagiya, Hiroaki Sagawa, Hideto Chono, Ikunoshin Kato