Abstract: A problem to be solved by the present invention is to provide a method for ameliorating pollakiuria and nocturia, in particular, nocturia caused by nocturnal polyuria by finding a composition that enhances the antidiuretic action of vasopressin or a vasopressin V2 receptor agonist. As a result of the studies, it has been found that imidafenacin enhances the antidiuretic action of vasopressin or the vasopressin V2 receptor agonist, whereby the present invention has been completed. According to the present invention, a composition containing imidafenacin can enhance the antidiuretic action of vasopressin or the vasopressin V2 receptor agonist, making it possible to ameliorate pollakiuria and nocturia, in particular, nocturia caused by nocturnal polyuria.

Abstract: A problem to be solved by the present invention is to provide a method for ameliorating pollakiuria and nocturia, in particular, nocturia caused by nocturnal polyuria by finding a composition that enhances the antidiuretic action of vasopressin or a vasopressin V2 receptor agonist. As a result of the studies, it has been found that imidafenacin enhances the antidiuretic action of vasopressin or the vasopressin V2 receptor agonist, whereby the present invention has been completed. According to the present invention, a composition containing imidafenacin can enhance the antidiuretic action of vasopressin or the vasopressin V2 receptor agonist, making it possible to ameliorate pollakiuria and nocturia, in particular, nocturia caused by nocturnal polyuria.

Abstract: A sheathed optical fiber cutting method and apparatus for cutting the sheathed optical fiber. In one embodiment, the sheathed optical fiber is rotated around its center axis against a cutting blade. An incision is made in an area of the sheathed optical fiber that is under tension from being bent. The incision makes a cut that is flat and perpendicular to the axis of the optical fiber. In one embodiment, the blade for making the incision is mounted in a vibration generator.

Abstract: A sheathed optical fiber cutting method and cutting apparatus for cutting the sheathed optical fiber, under such a condition that the sheathed optical fiber (12) is relatively rotated around its center axis (Ax) against a cutting blade (18) and bent, by making an incision in an area having a bent curvature larger than that of the center of the bent optical fiber along the center axis (Ax), from the tension-applied surface (12A) to which a tension is applied due to fiber bending toward the fiber center.