Patents by Inventor Takanori WASHIO

Takanori WASHIO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250084092
    Abstract: An object of the present invention is to provide a pharmaceutical composition, in particular, a compound suitable for preventing and/or treating inflammatory diseases and/or neurodegenerative disease. The present inventors have conducted intensive studies to find a compound having an inhibitory effect on NLRP3 inflammasome activation and found that an annulated pyridazine compound has an inhibitory effect on NLRP3 inflammasome activation, thus completing the present invention. The annulated pyridazine compound of the present invention is expected to serve as a prophylactic and/or therapeutic agent for inflammatory diseases and/or neurodegenerative diseases.
    Type: Application
    Filed: July 20, 2022
    Publication date: March 13, 2025
    Inventors: Yusuke Inagaki, Takuya Washio, Yuka Koizumi, Hiroki Toya, Yumi Yamashita, Ikumi Kuriwaki, Junko Maeda, Takanori Koike, Takashi Kamikubo, Susumu Yamaki, Kazuyuki Kuramoto, Kengo Saba, Hiroshi Tomiyama, Yoshinori Iwai, Akihiko Nakamura
  • Publication number: 20250006304
    Abstract: Disclosed is a method for controlling an information processing apparatus configured to analyze a sequence of nucleic acid obtained from a specimen of a subject, the method including: obtaining, on the basis of a plurality of first reads read by a sequencer, a result of mutation detection in an analysis target region in the sequence of the nucleic acid; generating, on the basis of second reads, out of the first reads, that correspond to at least one predetermined site selected from a base sequence in the analysis target region, information regarding a quality of a nucleic acid analysis with respect to the predetermined site; and outputting the information regarding the quality, irrespective of presence or absence of a mutation at the predetermined site.
    Type: Application
    Filed: June 28, 2024
    Publication date: January 2, 2025
    Applicants: National Cancer Center, SYSMEX CORPORATION
    Inventors: Takashi KOHNO, Kuniko SUNAMI, Hitoshi ICHIKAWA, Asuka SHIOTA, Kentaro FUJIWARA, Michiko YOSHIMOTO, Mio YUMURA, Takanori WASHIO
  • Publication number: 20230298689
    Abstract: A control method of controlling a computer to analyze, at a second facility, nucleic acid sequence data obtained, at a first facility, by a sequencer that reads a nucleic acid sequence, for a gene panel test, comprising receiving, from the first facility via a network, a sequence data set comprising a plurality of nucleic acid sequence data obtained by the sequencer corresponding to each of a plurality of library samples comprising a first library sample and a second library sample, which are prepared from a specimen of a subject, and link information indicating that the first library sample and the second library sample are prepared from the specimen of the same subject; analyzing a first sequence data and a second sequence data corresponding to each of the first library sample and the second library sample linked by the link information; and outputting analysis information based on an analysis result of the first sequence data and an analysis result of the second sequence data, is disclosed.
    Type: Application
    Filed: October 26, 2022
    Publication date: September 21, 2023
    Applicants: SYSMEX CORPORATION, RIKEN GENESIS CO., LTD.
    Inventors: Tatsuru WAKIMOTO, Yoshinori TANAKA, Takanori WASHIO
  • Publication number: 20230170043
    Abstract: A report generating method generates a report for reporting a level of pathogenicity of a genetic mutation. The report generating method obtains information on a genetic mutation detected in a gene panel test, generates an evaluation result for a plurality of evaluation items based on a first criterion for evaluating each of the evaluation items and at least information on the genetic mutation, determines the level of pathogenicity based on a second criterion for determining the level of pathogenicity and the evaluation result, determines an undetermined item for which the evaluation result is undetermined among the plurality of evaluation items, determines whether the level of pathogenicity is tentative based on a determination result of the undetermined item, and generates a report for reporting the level of pathogenicity according to the determination result of whether the level of pathogenicity is tentative.
    Type: Application
    Filed: November 23, 2022
    Publication date: June 1, 2023
    Applicant: SYSMEX CORPORATION
    Inventors: Yuuki IZUMI, Hayato NIIRO, Takanori WASHIO
  • Publication number: 20200082911
    Abstract: Provided is an analysis method including obtaining sequence information of nucleic acid contained in a measurement sample prepared by mixing a sample that contains subject-derived nucleic acid and a sample that contains non-subject-derived nucleic acid such that the measurement sample contains a previously determined amount of nucleic acid; and performing analysis on the obtained sequence information, wherein the performing of the analysis includes performing analysis on sequence information of the subject-derived nucleic acid in the obtained sequence information, and not performing, on sequence information of the non-subject-derived nucleic acid in the obtained sequence information, at least a part of the analysis to be performed on the sequence information of the subject-derived nucleic acid.
    Type: Application
    Filed: August 27, 2019
    Publication date: March 12, 2020
    Inventors: Takanori WASHIO, Reiko WATANABE
  • Publication number: 20200082912
    Abstract: Provided is an analysis method including obtaining sequence information of nucleic acid contained in a measurement sample prepared by mixing at least one sample that contains subject-derived nucleic acid and a sample that contains non-subject-derived nucleic acid such that the measurement sample contains a previously determined amount of nucleic acid; and outputting sequence information in which a data amount of sequence information per sample that contains subject-derived nucleic acid is a predetermined amount irrespective of the number of samples that contain subject-derived nucleic acid and that have been used in preparing the measurement sample.
    Type: Application
    Filed: August 27, 2019
    Publication date: March 12, 2020
    Inventors: Takanori WASHIO, Reiko WATANABE