Patents by Inventor Takao Aoyagi

Takao Aoyagi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10232321
    Abstract: A blood purification membrane capable of adsorbing creatinine which is a uremic toxin in the blood and purifying the blood, the blood purification membrane including fibers and particles adhered to the aforementioned fibers, wherein the aforementioned fibers are composed of a polymer insoluble in water, the aforementioned particles contain SiO2 and Al2O3, and pores capable of incorporating at least a portion of the aforementioned uremic toxin are provided in the aforementioned particles.
    Type: Grant
    Filed: August 25, 2014
    Date of Patent: March 19, 2019
    Assignee: NATIONAL INSTITUTE FOR MATERIALS SCIENCE
    Inventors: Mitsuhiro Ebara, Koki Namekawa, Takao Aoyagi
  • Publication number: 20160199789
    Abstract: A blood purification membrane capable of adsorbing creatinine which is a uremic toxin in the blood and purifying the blood, the blood purification membrane including fibers and particles adhered to the aforementioned fibers, wherein the aforementioned fibers are composed of a polymer insoluble in water, the aforementioned particles contain SiO2 and Al2O3, and pores capable of incorporating at least a portion of the aforementioned uremic toxin are provided in the aforementioned particles.
    Type: Application
    Filed: August 25, 2014
    Publication date: July 14, 2016
    Applicant: National Institute of Materials Science
    Inventors: Mitsuhiro EBARA, Koki NAMEKAWA, Takao AOYAGI
  • Publication number: 20150352209
    Abstract: The invention aims to provide a nanofiber having self-heating properties and biologically active substance release properties, which can release a drug at the same time as self-heating, and can be safely used on a human body without diffusing self-heating nanoparticles, a production method for the same, and a nonwoven fabric having self-heating properties and biologically active substance release capabilities.
    Type: Application
    Filed: January 10, 2014
    Publication date: December 10, 2015
    Applicant: NATIONAL INSTITUTE FOR MATERIALS SCIENCE
    Inventors: Mitsuhiro EBARA, Takao AOYAGI, Koichiro UTO
  • Publication number: 20090054596
    Abstract: A temperature-responsive polymer (hydrated graft structure) layer (2) composed of acrylamide derivative or the like exhibiting sensitive temperature-responsivity is immobilized to a magnetic particulate (1) composed of iron oxide or the like with a covalent bond. Further, an anticancer agent (3) is dispersed in the temperature-responsive polymer (2). The anticancer agent is ionically bonded to the temperature responsive polymer (hydrated graft structure).
    Type: Application
    Filed: August 25, 2005
    Publication date: February 26, 2009
    Applicant: Kagoshima University
    Inventor: Takao Aoyagi
  • Patent number: 6634010
    Abstract: An improved ASIC design support system is described. In accordance with the ASIC design support system, it is possible to easily download the latest versions of a necessary library (or libraries) and a necessary simulator. The ASIC design support system includes a web server which receives a request of the customer including the specification of the ASIC he wants to design. The web server serves to generate and transfer to the customer a library (or libraries) or a simulator required for designing said ASIC and performing simulation thereof.
    Type: Grant
    Filed: June 25, 2001
    Date of Patent: October 14, 2003
    Assignee: Kabushiki Kaisha Toshiba
    Inventors: Hisashi Ishigami, Takao Aoyagi, Hideki Taguchi
  • Patent number: 6495645
    Abstract: An acrylamide derivative of the following general formula (I) is used to prepare a polymer or copolymer: wherein R1 represents a hydrogen atom, a straight-chain or branched alkyl group containing 1 to 4 carbon atoms or a C3-6 cycloalkyl group, R2 and R3 each independently represent an alkylene group containing 1 to 6 carbon atoms or R2 and R3 may be combined to form a ring, X represents a hydrogen atom, an amino group, a hydroxyl group, a halogen atom, a carboxyl group or a —COOR4 group wherein R4 represents a C1-6 straight-chain or branched alkyl, C3-6 cycloalkyl, phenyl, substituted phenyl, benzyl or substituted benzyl group, and Y represents an amino group, a halogen atom, a carboxyl group or a —COOR4 group wherein R4 represents a C1-6 straight-chain or branched alkyl, C3-6 cycloalkyl, phenyl, substituted phenyl, benzyl or substituted benzyl group.
    Type: Grant
    Filed: August 30, 2001
    Date of Patent: December 17, 2002
    Inventors: Teruo Okano, Takao Aoyagi
  • Publication number: 20010056446
    Abstract: An improved ASIC design support system is described. In accordance with the ASIC design support system, it is possible to easily download the latest versions of a necessary library (or libraries) and a necessary simulator. The ASIC design support system includes a web server which receives a request of the customer including the specification of the ASIC he wants to design. The web server serves to generate and transfer to the customer a library (or libraries) or a simulator required for designing said ASIC and performing simulation thereof.
    Type: Application
    Filed: June 25, 2001
    Publication date: December 27, 2001
    Applicant: Kabushiki Kaisha Toshiba
    Inventors: Hisashi Ishigami, Takao Aoyagi, Hideki Taguchi
  • Patent number: 5624680
    Abstract: A hydrosilyl-terminated polyoxyethylene compound of the general formula (I), a quaternary-salt-terminated polyoxyethylene/polyorganosiloxane block copolymer of the general formula (II) derived from the above compound, and a percutaneous drug absorption promoter comprising the above copolymer (II). The copolymer is usable as a percutaneous absorption promoter having a good drug absorption promoting effect and being effective for various drugs.
    Type: Grant
    Filed: January 23, 1996
    Date of Patent: April 29, 1997
    Assignee: Sagami Chemical Research Center
    Inventors: Yu Nagase, Takao Aoyagi, Tomoko Akimoto
  • Patent number: 5616317
    Abstract: A polycationic microbicidal and algaecidal agent containing as an active ingredient a polymer comprising repeating units represented by the formula (I) and having a number average molecular weight of at least 1,000, and a microbicidal and algaecidal method using the polymer: ##STR1## (wherein A is a single bond, an oxygen atom, a phenylene group, a dioxyethylene group or a tetramethyldisiloxane group, X.sub.1.sup.- and X.sub.2.sup.- may be the same or different and are counter anions in quaternary salts, p and q may be the same or different and are integers of from 1 to 6, and m is an integer of from 1 to 6, provided that A, X.sub.1.sup.-, X.sub.2.sup.-, p, q and m may be the same or optionally different for every repeating unit).
    Type: Grant
    Filed: June 14, 1995
    Date of Patent: April 1, 1997
    Assignees: Sagami Chemical Research Center, K.multidot.I Chemical Industry Co., Ltd.
    Inventors: Yu Nagase, Takao Aoyagi, Tomoko Akimoto, Kazunori Tanaka, Kouichi Iwabuchi, Yoshihiro Konagai
  • Patent number: 5417983
    Abstract: The present invention related to a drug release controlling material responsive to changes in temperature comprising the polyester gel which is obtained by polymerization of a polyfunctional macromonomer represented by the general formula (I): ##STR1## wherein R.sup.1 represents a hydrogen atom or an alkyl group having from 1 to 6 carbon atoms, X.sup.1 represents a hydrogen atom, a halogen atom, a cyano group, an alkyl group having from 1 to 6 carbon atoms or a phenyl group, A represents an aliphatic polyester chain, m is 0 or 1, and p, which may be the same or different in each branched chain, represents an integer of from 0 to 6, optionally with a polyethylene glycol derivative which contains polymerizable group(s) at the end(s). The drug release controlling material has an on-off control function of drug release responsive to changes in temperature depending upon the gel transition of the aliphatic polyester gel.
    Type: Grant
    Filed: November 9, 1994
    Date of Patent: May 23, 1995
    Assignee: Sagami Chemical Research Center
    Inventors: Yu Nagase, Takao Aoyagi, Fusae Miyata
  • Patent number: 5200488
    Abstract: A polyorganosiloxane having a quaternary salt at its one terminal, of the following formula (I): ##STR1## wherein A is ##STR2## X.sup.- is a counter anion in the quaternary salt; each of R.sup.1 to R.sup.5 which may be the same or different, is an alkyl group, a substituted alkyl group or a phenyl group; Y is a C.sub.1-6 linear or branched bivalent alkylene or oxyalkylene group; and n is an integer of at least 1, provided that when n is 2 or more, each of R.sup.4 and R.sup.5 may be the same or different, wherein each of R.sup.6 to R.sup.8 which may be the same or different, is an alkyl group, a substituted alkyl group or a phenyl group, or R.sup.6 to R.sup.8 together form a ring and/or an unsaturated bond; R is a C.sub.1-6 alkyl group or a phenyl group; m is an integer of from 0 to 3, provided that when m is 2 or 3, R may be the same of different; and each of R.sup.9 to R.sup.11 which may be the same or different, is a phenyl group, a benzyl group or a C.sub.1-6 alkyl group.
    Type: Grant
    Filed: November 4, 1991
    Date of Patent: April 6, 1993
    Assignee: Sagami Chemical Research Center
    Inventors: Yu Nagase, Takao Aoyagi, Tomoko Nakamura
  • Patent number: 4968539
    Abstract: A polymer membrane for delivering a drug is provided. The membrane is capable of regulating the delivery of the drug and comprises (A) a porous hydrophobic polymer membrane having a pore diameter of not larger than 3 .mu.m and a porosity of 10 to 90% which is immobilized with (B) a specific liquid crystal-forming compound having a gel/liquid crystal transition temperature in the range of 25.degree. to 45.degree. C.
    Type: Grant
    Filed: November 30, 1988
    Date of Patent: November 6, 1990
    Assignee: Lion Corporation
    Inventors: Takao Aoyagi, Shuji Sato, Minako Yasu, Iwao Nozawa, Yousuke Suzuki