Patents by Inventor Takao Aoyagi
Takao Aoyagi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240423242Abstract: The present invention relates to an feed additive comprising a licorice extract for improving the quality of embryos obtained after the superovulation treatment, as well as, a method for improving the quality of the embryos obtained after the superovulation treatment comprising rearing to a mammal with superovulation treatment using a feed added with licorice extract.Type: ApplicationFiled: September 3, 2024Publication date: December 26, 2024Applicants: COKEY SYSTEMS CO., LTD.Inventors: Yoshito AOYAGI, Masateru KOIWA, Takao ONISHI
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Patent number: 10232321Abstract: A blood purification membrane capable of adsorbing creatinine which is a uremic toxin in the blood and purifying the blood, the blood purification membrane including fibers and particles adhered to the aforementioned fibers, wherein the aforementioned fibers are composed of a polymer insoluble in water, the aforementioned particles contain SiO2 and Al2O3, and pores capable of incorporating at least a portion of the aforementioned uremic toxin are provided in the aforementioned particles.Type: GrantFiled: August 25, 2014Date of Patent: March 19, 2019Assignee: NATIONAL INSTITUTE FOR MATERIALS SCIENCEInventors: Mitsuhiro Ebara, Koki Namekawa, Takao Aoyagi
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Publication number: 20160199789Abstract: A blood purification membrane capable of adsorbing creatinine which is a uremic toxin in the blood and purifying the blood, the blood purification membrane including fibers and particles adhered to the aforementioned fibers, wherein the aforementioned fibers are composed of a polymer insoluble in water, the aforementioned particles contain SiO2 and Al2O3, and pores capable of incorporating at least a portion of the aforementioned uremic toxin are provided in the aforementioned particles.Type: ApplicationFiled: August 25, 2014Publication date: July 14, 2016Applicant: National Institute of Materials ScienceInventors: Mitsuhiro EBARA, Koki NAMEKAWA, Takao AOYAGI
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Publication number: 20150352209Abstract: The invention aims to provide a nanofiber having self-heating properties and biologically active substance release properties, which can release a drug at the same time as self-heating, and can be safely used on a human body without diffusing self-heating nanoparticles, a production method for the same, and a nonwoven fabric having self-heating properties and biologically active substance release capabilities.Type: ApplicationFiled: January 10, 2014Publication date: December 10, 2015Applicant: NATIONAL INSTITUTE FOR MATERIALS SCIENCEInventors: Mitsuhiro EBARA, Takao AOYAGI, Koichiro UTO
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Publication number: 20090054596Abstract: A temperature-responsive polymer (hydrated graft structure) layer (2) composed of acrylamide derivative or the like exhibiting sensitive temperature-responsivity is immobilized to a magnetic particulate (1) composed of iron oxide or the like with a covalent bond. Further, an anticancer agent (3) is dispersed in the temperature-responsive polymer (2). The anticancer agent is ionically bonded to the temperature responsive polymer (hydrated graft structure).Type: ApplicationFiled: August 25, 2005Publication date: February 26, 2009Applicant: Kagoshima UniversityInventor: Takao Aoyagi
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Patent number: 6634010Abstract: An improved ASIC design support system is described. In accordance with the ASIC design support system, it is possible to easily download the latest versions of a necessary library (or libraries) and a necessary simulator. The ASIC design support system includes a web server which receives a request of the customer including the specification of the ASIC he wants to design. The web server serves to generate and transfer to the customer a library (or libraries) or a simulator required for designing said ASIC and performing simulation thereof.Type: GrantFiled: June 25, 2001Date of Patent: October 14, 2003Assignee: Kabushiki Kaisha ToshibaInventors: Hisashi Ishigami, Takao Aoyagi, Hideki Taguchi
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Patent number: 6495645Abstract: An acrylamide derivative of the following general formula (I) is used to prepare a polymer or copolymer: wherein R1 represents a hydrogen atom, a straight-chain or branched alkyl group containing 1 to 4 carbon atoms or a C3-6 cycloalkyl group, R2 and R3 each independently represent an alkylene group containing 1 to 6 carbon atoms or R2 and R3 may be combined to form a ring, X represents a hydrogen atom, an amino group, a hydroxyl group, a halogen atom, a carboxyl group or a —COOR4 group wherein R4 represents a C1-6 straight-chain or branched alkyl, C3-6 cycloalkyl, phenyl, substituted phenyl, benzyl or substituted benzyl group, and Y represents an amino group, a halogen atom, a carboxyl group or a —COOR4 group wherein R4 represents a C1-6 straight-chain or branched alkyl, C3-6 cycloalkyl, phenyl, substituted phenyl, benzyl or substituted benzyl group.Type: GrantFiled: August 30, 2001Date of Patent: December 17, 2002Inventors: Teruo Okano, Takao Aoyagi
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Publication number: 20010056446Abstract: An improved ASIC design support system is described. In accordance with the ASIC design support system, it is possible to easily download the latest versions of a necessary library (or libraries) and a necessary simulator. The ASIC design support system includes a web server which receives a request of the customer including the specification of the ASIC he wants to design. The web server serves to generate and transfer to the customer a library (or libraries) or a simulator required for designing said ASIC and performing simulation thereof.Type: ApplicationFiled: June 25, 2001Publication date: December 27, 2001Applicant: Kabushiki Kaisha ToshibaInventors: Hisashi Ishigami, Takao Aoyagi, Hideki Taguchi
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Patent number: 5624680Abstract: A hydrosilyl-terminated polyoxyethylene compound of the general formula (I), a quaternary-salt-terminated polyoxyethylene/polyorganosiloxane block copolymer of the general formula (II) derived from the above compound, and a percutaneous drug absorption promoter comprising the above copolymer (II). The copolymer is usable as a percutaneous absorption promoter having a good drug absorption promoting effect and being effective for various drugs.Type: GrantFiled: January 23, 1996Date of Patent: April 29, 1997Assignee: Sagami Chemical Research CenterInventors: Yu Nagase, Takao Aoyagi, Tomoko Akimoto
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Patent number: 5616317Abstract: A polycationic microbicidal and algaecidal agent containing as an active ingredient a polymer comprising repeating units represented by the formula (I) and having a number average molecular weight of at least 1,000, and a microbicidal and algaecidal method using the polymer: ##STR1## (wherein A is a single bond, an oxygen atom, a phenylene group, a dioxyethylene group or a tetramethyldisiloxane group, X.sub.1.sup.- and X.sub.2.sup.- may be the same or different and are counter anions in quaternary salts, p and q may be the same or different and are integers of from 1 to 6, and m is an integer of from 1 to 6, provided that A, X.sub.1.sup.-, X.sub.2.sup.-, p, q and m may be the same or optionally different for every repeating unit).Type: GrantFiled: June 14, 1995Date of Patent: April 1, 1997Assignees: Sagami Chemical Research Center, K.multidot.I Chemical Industry Co., Ltd.Inventors: Yu Nagase, Takao Aoyagi, Tomoko Akimoto, Kazunori Tanaka, Kouichi Iwabuchi, Yoshihiro Konagai
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Patent number: 5417983Abstract: The present invention related to a drug release controlling material responsive to changes in temperature comprising the polyester gel which is obtained by polymerization of a polyfunctional macromonomer represented by the general formula (I): ##STR1## wherein R.sup.1 represents a hydrogen atom or an alkyl group having from 1 to 6 carbon atoms, X.sup.1 represents a hydrogen atom, a halogen atom, a cyano group, an alkyl group having from 1 to 6 carbon atoms or a phenyl group, A represents an aliphatic polyester chain, m is 0 or 1, and p, which may be the same or different in each branched chain, represents an integer of from 0 to 6, optionally with a polyethylene glycol derivative which contains polymerizable group(s) at the end(s). The drug release controlling material has an on-off control function of drug release responsive to changes in temperature depending upon the gel transition of the aliphatic polyester gel.Type: GrantFiled: November 9, 1994Date of Patent: May 23, 1995Assignee: Sagami Chemical Research CenterInventors: Yu Nagase, Takao Aoyagi, Fusae Miyata
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Patent number: 5200488Abstract: A polyorganosiloxane having a quaternary salt at its one terminal, of the following formula (I): ##STR1## wherein A is ##STR2## X.sup.- is a counter anion in the quaternary salt; each of R.sup.1 to R.sup.5 which may be the same or different, is an alkyl group, a substituted alkyl group or a phenyl group; Y is a C.sub.1-6 linear or branched bivalent alkylene or oxyalkylene group; and n is an integer of at least 1, provided that when n is 2 or more, each of R.sup.4 and R.sup.5 may be the same or different, wherein each of R.sup.6 to R.sup.8 which may be the same or different, is an alkyl group, a substituted alkyl group or a phenyl group, or R.sup.6 to R.sup.8 together form a ring and/or an unsaturated bond; R is a C.sub.1-6 alkyl group or a phenyl group; m is an integer of from 0 to 3, provided that when m is 2 or 3, R may be the same of different; and each of R.sup.9 to R.sup.11 which may be the same or different, is a phenyl group, a benzyl group or a C.sub.1-6 alkyl group.Type: GrantFiled: November 4, 1991Date of Patent: April 6, 1993Assignee: Sagami Chemical Research CenterInventors: Yu Nagase, Takao Aoyagi, Tomoko Nakamura
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Patent number: 4968539Abstract: A polymer membrane for delivering a drug is provided. The membrane is capable of regulating the delivery of the drug and comprises (A) a porous hydrophobic polymer membrane having a pore diameter of not larger than 3 .mu.m and a porosity of 10 to 90% which is immobilized with (B) a specific liquid crystal-forming compound having a gel/liquid crystal transition temperature in the range of 25.degree. to 45.degree. C.Type: GrantFiled: November 30, 1988Date of Patent: November 6, 1990Assignee: Lion CorporationInventors: Takao Aoyagi, Shuji Sato, Minako Yasu, Iwao Nozawa, Yousuke Suzuki