Abstract: The present invention provides an ISDN-containing patch that causes minimal occurrence of skin rash and has excellent percutaneous absorption and adhesive strength. The present invention discloses an isorbide dinitrate-containing patch comprising: an adhesive layer formed on a flexible support, wherein said layer comprises an adhesive composition containing adhesive and isosorbide dinitrate, the adhesive being composed of silicone-based adhesive (A) and polyvinyl acetate-based adhesive (B), their weight ratio being A:B=85:15 to 15:85, and the weight ratio of isosorbide dinitrate (C) to the adhesives (A+B) being (A+B):C=90:10 to 60:40.

Abstract: A method and apparatus is described for selecting an entry stored in a data processing system, and specifically a destination in a vehicle navigation system. The system includes a display, a scrolling control having first and second controls, and a selecting control. Using the scrolling control, the user of the system scrolls through a plurality of stored destinations on the display. Each destination is made up of a plurality of alphanumeric symbols, the destinations forming an alphabetically and numerically organized list. The scrolling is accomplished by using the first control of the scrolling control. A character position selector is used to select a character position in a first indicated destination and the second control of the scrolling control is used to jump to subsets of destinations with the next or previous character position as compared to a currently indicated destination. The selecting control is then used to enter a desired destination.

Abstract: A vehicle navigation system displays arrow icons to a driver indicating the directions he must follow from each of one or more turning points on his route to keep the driver from passing inadvertently an intersection in which he must change the vehicle's direction of advance or from turning in an intersection prior to the intersection previously chosen for a turn. Road anomalies, such as sharp curves or U turns are also displayed. The arrow icons are alternatively created from computed directions of the vehicle's advance or stored in an X-Y storage unit from which an arrow icon best fitting the required guidance is selected. The stored arrow icons include straight road, single turns, and multiple turns. The selected arrow is displayed to the driver. An embodiment calculates turns and curves with angles which match the actual angles of the turns, and radii and turning angles of curves.

Abstract: A navigation system mounted on a vehicle computes in advance an optimal route from a starting point to a destination. When the vehicle travels off the optimal route, the navigation system detects an off-route deviation. When an off-route deviation is detected, the system computes a restoration route from the vehicle's present position to a selected point on the optimal route and rapidly displays navigational information to guide the vehicle thereto. Thus there is no need for the system to compute a new optimal route from the present position to the destination, and there is no delay in supplying the driver with navigational information.

Abstract: A navigation system for a vehicle enables an operator to know a calculated optimal path from a starting point to a destination before departure. After the optimal path is calculated, a preview function allows the operator to sequentially view the calculated optimal path either prior to departure or at any point along the optimal path. A cancel function allows the operator to cancel a displayed portion of the optimal path and to request calculation and display of an alternate optimal path which does not employ the canceled portion of the original optimal path.

Abstract: Bacteria such as E. coli which are easy in manipulation are transformed by the gene encoding a ethylene-forming enzyme, and ethylene is formed by the transformants.

Abstract: Provided are .alpha.-chain-modified isocarbacyclins of which the .alpha.-chain is modified with a phenylene group, a cycloalkylene group or a thiophendiyl group, and these .alpha.-chain-modified isocarbacyclins show the activity for inhibiting the DNA synthesis of human smooth muscle cell and are expected to be capable of inhibiting the hypertrophy of a blood vessel.

Abstract: A navigation system mounted on a vehicle displays a primary direction indication image on a display unit. This primary direction indication image has a proximal portion that represents a road along which the vehicle is now moving and a direction indication portion that represents a road which the vehicle is to enter at the next intersection. One or more auxiliary direction indication images, with direction indication portions that represent other roads connected to the next intersection, are displayed on the display unit together with the primary direction indication image. The direction indication portion of the auxiliary direction indication image extends from the distal end of the proximal portion of the primary direction indication image.

Abstract: A boiling water reactor comprises a reactor pressure vessel accommodated in a vertical fashion, a core disposed at a low portion in the reactor pressure vessel, a plurality of control rods to be inserted from an upper side of the core into the spaces between adjacent fuel assemblies and withdrawn therefrom upwardly, a shroud surrounding the fuel assemblies so as to define the core and having an upper end opening, a shroud head which closes the upper end opening of the shroud and through which the control rods are inserted or withdrawn, a separator standing upward from the shroud head to carry out gas-water separation of steam generated from the core, a fixing pedestal disposed above the separator, a control rod driving mechanism mounted on the fixing pedestal and adapted to drive the control rods, a drier unit including a plurality of drier elements annularly arranged along an upper inner wall surface of the reactor pressure vessel and adapted to dry the steam passing through the steam flow hole of the fixing

Abstract: In an apparatus including a fluid circulation unit for allowing a fluid in a container to be circulated along a passage in the container, a flow rate measuring apparatus includes a rotational speed transducer for detecting the rotational speed of a motor for driving the fluid circulation unit and a pipe network model calculator for receiving a rotational speed signal from the rotational speed transducer. The model calculator has an initially programmed pipe network model corresponding to flows in the container and calculates the flow rate at a corresponding location of the model with the rotational speed of the circulation unit replaced by constants of the model and hence calculates a flow rate of the fluid at that location in a real passage.

Abstract: A process for producing a 1.alpha.,3.beta.,24-trihydroxy-.DELTA..sup.5 -steroid represented by the formula (II): ##STR1## wherein R.sub.1 and R.sub.2, independently, represent a hyrogen atom, or R.sub.1 and R.sub.2 together form a single bond, R.sub.3 represents an unsubstituted or halogen-substituted lower alkyl, and R.sub.4 represents a hydrogen atom, hydroxy or a protected hydroxy, comprising reducing a 1.alpha.,2.alpha.-epoxy-.DELTA..sup.4,6 -3,24-dioxosteroid represented by the formula (I) ##STR2## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 have the same meanings as defined in formula (II), using an alkaline metal or alkaline earth metal and a proton donor in a solvent comprising ammonia or amine characterized in that at an early stage of the reaction, the 1.alpha.,2.alpha.-epoxy-.DELTA..sup.

Abstract: A nuclear reactor internal pump has a pump shaft connected to a motor and rotatably passing through the bottom of a nuclear reactor pressure vessel, an impeller fitted to a front end portion of the pump shaft, a diffuser disposed on the downstream side of the impeller and having an inner cylinder fixed to the bottom of the reactor pressure vessel to surround the pump shaft, a purge water passage defined between the pump shaft and the inner cylinder to communicate with the inside of the reactor pressure vessel and a purge water supply device for supplying purge water to reactor pressure vessel through the passage. Further, the nuclear reactor internal pump comprises a clad dropping preventive device for trapping clad coming from the reactor pressure vessel in the passage to prevent the clad from dropping.

Abstract: C.sub.3 and/or C.sub.4 hydrocarbons(s) is produced by the aerobic cultivation of a microorganism belonging to a wide variety of genera of Fungi, Yeasts, Bacteria and Actinomycetes. Industrial wastes and various biomass can be employed as nutrient source in the cultivation.

Abstract: A method of recovering useful components at least containing dimethyl terephthalate from high-boiling byproducts occurring in the production of dimethyl terephthalate, which comprises oxidizing p-xylene and/or methyl p-toluate with a molecular oxygen-containing gas in the presence of a heavy metal oxidation catalyst, subjecting the resulting oxidation product to esterification with methanol, separating dimethyl terephthalate and esters having lower boiling points than dimethyl terephthalate from the esterification reaction product by distillation, and thereafter treating the distillation residue containing byproducts having higher boiling points than dimethyl terephthalate with methanol to recover at least dimethyl terephthalate from the treated product; wherein the treatment of the distillation residue with methanol is carried out at a temperature of 110.degree. to 240.degree. C. under a pressure sufficient to maintain methanol in the liquid phase.

Abstract: Mixtures of saturated or unsaturated C.sub.2 -C.sub.5 hydrocarbons are produced by aerobically cultivating a microorganism belonging to a wide variety of genera Fungi, Yeasts, Bacteria and Actinomycetes in a water-containing medium, and recovering the hydrocarbon mixtures from the liquid phase or/and gaseous ambience of the medium. Industrial wastes and various biomass can be employed as nutrient sources in the cultivation.

Abstract: Disclosed is a process for the recovery of aromatic carboxylic acid or ester thereof from the residue fraction of the oxidation or esterification reaction mixture resulting from the oxidation or oxidation and esterification of an aromatic compound having at least one methyl or formyl group directly bonded to a ring carbon atom. The process comprises treating the residue fraction with hydrogen and a hydrogenation catalyst.

Abstract: In the process for preparing dimethyl terephthalate by oxydizing p-xylene and/or methyl p-toluate with molecular oxygen or a molecular oxygen-containing gas in the presence of a heavy metal catalyst, esterifying the resulting oxidation reaction mixture with methanol, followed by submitting the resulting esterification reaction mixture to distillation to separate dimethyl terephthalate and fractions of lower boiling point than dimethyl terephthalate, and thereafter recycling to said oxidation step (A) the distillation residue containing said heavy metal catalyst and/or (B) the extract portion containing said heavy metal catalyst obtained by further extraction treatment of said distillation residue (A), the improvement which comprises contact-treating said distillation residue (A) or said extract portion (B) with methanol prior to recycling same.