Patents by Inventor Takao Furusho
Takao Furusho has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 5878747Abstract: A condom prophylactic against AIDS infection coated with acidic polysaccharides is provided which has an antiviral action and a method of the manufacture thereof. The acidic polysaccharides can be polysaccharides, protein-bound saccharides and glycolipids such as extracts from sea-weeds, extracts from Procaryomycota and Eucaryomycota, carrageenan and so on which have acidic groups such as sulfuric acid group in a portion of polysaccharides. A condom is coated with a solution of said acidic polysaccharides, and optionally with a lubricant. AIDS infection can be prevented without side effect by using a condom of the present invention.Type: GrantFiled: December 22, 1994Date of Patent: March 9, 1999Assignee: Fuji Latex Co., Ltd.Inventors: Yutaka Enomoto, Masahiko Fujii, Takao Furusho, Naoki Yamamoto
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Patent number: 5089481Abstract: Disclosed herein are polysaccharides extracted from marine algae and an antiviral drug containing as active ingredient polysaccharides extracted from seaweeds.Type: GrantFiled: November 15, 1990Date of Patent: February 18, 1992Assignee: Kureha Kagaku Kogyo Kabushiki KaishaInventors: Shigeaki Muto, Koichi Niimura, Minoru Oohara, Yoshiharu Oguchi, Kenichi Matsunaga, Kunitaka Hirose, Junji Kakuchi, Norifumi Sugita, Takao Furusho, Chikao Yoshikumi, Masaaki Takahashi
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Patent number: 5008243Abstract: Disclosed herein is a pharmaceutical composition having antirheumatic activity, antithrombotic activity, analgetic activity, antipyretics activity, anti-hyperlipemic activity and anti-inflammatory activity and activities of reducing the level of blood sugar, raising the coronary blood flow, improving the capability of deformation of erythrocytes, reducing the blood pressure, ameliorating proteinuria and proteinemia and regulating production or metabolism of prostaglandins in a mammal in dosage unit form, which comprises a dosage effective to produce said activities of a glycoprotein having a molecular weight of 5000 to 300,000 as determined by ultracentrifugal method and about 18 to 38% by weight of proteins, produced by culturing a basidiomycetous fungal species belonging to the genus Coriolus, extracting the thus proliferated mycelia or fruit bodies with hot water or aqueous alkali solution and removing low molecular weight substances having a molecular weight of less than 5000 from the extract.Type: GrantFiled: December 16, 1988Date of Patent: April 16, 1991Assignee: Kureha Kagaku Kogyo Kabushiki KaishaInventors: Masanori Ikuzawa, Yoshiharu Oguchi, Kenichi Matsunaga, Noriyuki Toyoda, Takao Furusho, Takayoshi Fujii, Chikao Yoshikumi
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Patent number: 4985543Abstract: Disclosed herein are lectins extracted form a plant of the class Dicotyledoneae and an antiretoviral drug comprising as an active ingredient an effective amount of the lectins.Type: GrantFiled: June 17, 1988Date of Patent: January 15, 1991Assignee: Kureha Kagaku Kogyo Kabushiki KaishaInventors: Norifumi Sugita, Koichi Niimura, Yoshiharu Oguchi, Kunitaka Hirose, Kenichi Matsunaga, Minoru Oohara, Shigeaki Muto, Junji Kakuchi, Takao Furusho, Chikao Yoshikumi, Masaaki Takahashi
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Patent number: 4820689Abstract: Disclosed herein is a pharmaceutical composition having antirheumatic activity, antithrombotic activity, analgetic activity, antipyretic activity, anti-hyperlipemic activity and anti-inflammatory activity and activities of reducing the level of blood sugar, raising the coronary blood flow, improving the capability of deformation of erythrocytes, reducing the blood pressure, ameliorating proteinuria and proteinemia and regulating production or metabolism of prostaglandins in a mammal in dosage unit form, which comprises a dosage effective to produce said activities of a glycoprotein having a molecular weight of 5000 to 300000 as determined by ultracentrifugal method and about 18 to 38% by weight of proteins, produced by culturing a basidiomycetous fungal species belonging to the genus Coriolus, extracting the thus proliferated mycelia or fruit bodies with hot water or aqueous alkali solution and removing low molecular weight substances having a molecular weight of less than 5000 from the extract.Type: GrantFiled: August 22, 1986Date of Patent: April 11, 1989Assignee: Kureha Kagaku Kogyo Kabushiki KaishaInventors: Masanori Ikuzawa, Yoshiharu Oguchi, Kenichi Matsunaga, Noriyuki Toyoda, Takao Furusho, Takayoshi Fujii, Chikao Yoshikumi
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Patent number: 4758558Abstract: Disclosed herein are the derivatives of substituted cephalosporanic acid represented by the formula (I): ##STR1## wherein R.sup.1 represents a 4-pyridylthiomethyl group, an alpha-aminobenzyl group, a cyanomethyl group or a 1-tetrazolylmethyl group; R.sup.2 represents a hydrogen atom, an acetoxy group or a (5-methyl-1,3,4-thiadiazol-2-yl)thio group; R.sup.3 represents a hydrogen atom, a hydroxyl group, a carbamoyl group, an alkyl group having 1 to 4 carbon atoms or --(CONH).sub.m (CH.sub.2).sub.n --COOH wherein m is 0 or 1, n is 0, 1 or 2 and the carboxyl group may have been converted to a salt or an ester thereof; p is 0, 1 or 2 and X represents carbon atom or nitrogen atom, and antibiotics comprising the derivatives of substituted cephalosporanic acid represented by the formula (I).Type: GrantFiled: May 19, 1986Date of Patent: July 19, 1988Assignee: Kureha Kagaku Kogyo Kabushiki KaishaInventors: Akihiko Kanno, Shigeaki Muto, Koichi Niimura, Takao Ando, Takayoshi Fujii, Masahiko Fujii, Takao Furusho, Chikao Yoshikumi
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Patent number: 4734409Abstract: Disclosed herein are a cephalosporin derivative represented by the formula (I): ##STR1## wherein R.sup.1 represents a halogenoalkyl group, a salt and ester thereof, a process for producing the same, and a pharmaceutical composition and an antibacterial agent comprising the same.Type: GrantFiled: February 15, 1985Date of Patent: March 29, 1988Assignee: Kureha Kagaku Kogyo Kabushiki KaishaInventors: Shigeaki Muto, Chikao Yoshikumi, Takao Furusho, Isamu Motokawa, Yoko Onishi, Akihiko Kanno, Takayoshi Fujii, Takao Ando
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Patent number: 4690920Abstract: Disclosed herein are a derivative of a substituted cephalosporanic acid, represented by the formula (I): ##STR1## wherein p is 0, 1 or 2 and R.sup.1 represents a hydrogen atom, a hydroxyl group, a carbamoyl group, an alkyl group having 1 to 4 carbon atoms or --(CONH).sub.m (CH.sub.2).sub.n --COOH wherein m is 0 or 1; n is 0, 1 or 2 and the carboxyl group may have been converted to the salt or the ester thereof, and an antibiotic comprising a derivative of substituted cephalosporanic acid represented by the formula (I).Type: GrantFiled: December 20, 1983Date of Patent: September 1, 1987Assignee: Kureha Kagaku Kogyo Kabushiki KaishaInventors: Akihiko Kanno, Shigeaki Muto, Koichi Niimura, Takao Ando, Takayoshi Fujii, Masahiko Fujii, Takao Furusho, Chikao Yoshikumi
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Patent number: 4681877Abstract: Disclosed herein are 7-beta-[2-(2-amino-4-thiazolyl)-2-methoxyiminoacetamido]-3-(2-amino-1,3,4- thiadiazolyl-5-thiomethyl)-3-cepheme-4-carboxylic acid, salts thereof and pivaloyloxymethyl ester thereof, and a pharmaceutical composition containing the same as an active ingredient.Type: GrantFiled: December 16, 1983Date of Patent: July 21, 1987Assignee: Kureha Kagaku Kogyo Kabushiki KaishaInventors: Shigeaki Muto, Takao Ando, Takayoshi Fujii, Akihiko Kanno, Yoko Onishi, Isamu Motokawa, Takao Furusho, Chikao Yoshikumi
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Patent number: 4663438Abstract: Disclosed herein is a nucleic acid-containing glycoprotein having molecular weight of 5,000 to 300,000 as determined by ultracentrifugal method; the weight ratio of protein moiety thereof determined by Lowry-Folin's method to saccharide moiety thereof determined by phenol-sulfuric acid method of in the range of 50/50 to 80/20; N-terminal amino acid thereof consisting essentially of tyrosine, leucine or alanine; leucine-phenylalanine-valine as amino acid sequence at C-terminal thereof; the elementary composition consisting essentially of 35.2 to 49.3% of C, 4.8 to 8.0% of H, 4.3 to 12.3% of N, trace to 2.5% of S, trace to 1.2% of P and the balance of O; the isoelectric point of in the range of pH 2.5 to 5.0; and nucleic acid as a component.Type: GrantFiled: March 25, 1985Date of Patent: May 5, 1987Assignee: Kureha Kagaku Kogyo Kabushiki KaishaInventors: Chikao Yoshikumi, Takayoshi Fujii, Takao Furusho, Kenichi Matsunaga, Minoru Ohara, Akira Kobayashi
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Patent number: 4540689Abstract: A penicillin derivative having an antibacterial activity similar to a penicillin antibiotic in a living body without affecting the intestinal bacterial colonies, a process for preparing the derivative and a pharmaceutical composition in a dosage unit form containing the derivative as an active ingredient are disclosed.Type: GrantFiled: September 16, 1982Date of Patent: September 10, 1985Assignee: Kureha Kagaku Kogyo Kabushiki KaishaInventors: Shigeaki Muto, Kouichi Niimura, Takao Ando, Akihiko Kanno, Takao Furusho, Chikao Yoshikumi
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Patent number: 4496561Abstract: A cephalosporin derivative having an antibacterial activity similar to a cephalosporin antibiotic in living bodies without affecting the intestinal bacterial colonies, a method for preparing the derivative and a pharmaceutical composition in a dosage unit form containing the derivative as an active ingredient are disclosed.Type: GrantFiled: September 16, 1982Date of Patent: January 29, 1985Assignee: Kureha Kagaku Kogyo Kabushiki KaishaInventors: Shigeaki Muto, Kouichi Niimura, Takao Ando, Akihiko Kanno, Takao Furusho, Chikao Yoshikumi
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Patent number: 4496574Abstract: A penicillin derivative having an antibacterial activity similar to a penicillin antibiotic in a living body without affecting the intestinal bacterial colonies, a process for preparing the derivative and a pharmaceutical composition in a dosage unit form containing the derivative as an active ingredient are disclosed.Type: GrantFiled: September 16, 1982Date of Patent: January 29, 1985Assignee: Kureha Kagaku Kogyo Kabushiki KaishaInventors: Shigeaki Muto, Kouichi Niimura, Takao Ando, Akihiko Kanno, Takao Furusho, Chikao Yoshikumi
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Patent number: 4446137Abstract: A compound having the general formula (I) is derived from a cephalosporin; ##STR1## wherein R' is a hydrogen atom, an alkyl group having 1 to 4 atoms or an alkali metal and R is --CH.sub.2 COOR', --CH.sub.2 CH.sub.2 SR', ##STR2## or --CH.sub.2 CH.sub.2 COOR' wherein R' is defined above. A pharmaceutical composition containing the compound is excellent in an antibacterial activity, the activity being recovered by the action of an activating enzyme in a living body although the compound per se shows a low activity against the beneficial bacterial colonies in a living body.Type: GrantFiled: September 16, 1982Date of Patent: May 1, 1984Assignee: Kureha Kagaku Kogyo Kabushiki KaishaInventors: Shigeaki Muto, Kouichi Niimura, Takao Ando, Masahiko Fujii, Takao Furusho, Chikao Yoshikumi
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Patent number: 4439434Abstract: A compound having the general formula (I) is derived from a cephalosporin; ##STR1## wherein R' is a hydrogen atom, an alkyl group having 1 to 4 carbon atoms or an alkali metal.A pharmaceutical composition containing the compound is excellent in an antibacterial activity, the activity being recovered by the action of an activating enzyme in a living body although the compound per se shows a low activity against the beneficial bacterial colonies in a living body.Type: GrantFiled: September 16, 1982Date of Patent: March 27, 1984Assignee: Kureha Kagaku Kogyo Kabushiki KaishaInventors: Shigeaki Muto, Kouichi Niimura, Takao Ando, Masahiko Fujii, Takao Furusho, Chikao Yoshikumi
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Patent number: 4162939Abstract: The Basidiomycetes belonging to the genus Coriolus of family Polyporaceae are cultivated by using a glucose-yeast extract medium with the mixed ratio of glucose to yeast extract being within a specified range to improve the yield of mycelia obtained by the cultivation.Type: GrantFiled: August 12, 1977Date of Patent: July 31, 1979Assignee: Kureha Kagaku Kogyo Kabushiki KaishaInventors: Chikao Yoshikumi, Takao Furusho, Kenichi Matsunaga, Noriyuki Toyoda