Patents by Inventor Takao Hamakubo

Takao Hamakubo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Screening method for SREBP pathway-specific inhibitors
    Publication number: 20030203392
    Abstract: This invention provides a screening method for sterol regulatory element binding protein (SREBP) pathway-specific inhibitors using a mutant cultured cell, as well as therapeutic agents for hyperlipemia, arterial sclerosis, obesity or cancer containing an SREBP pathway-specific inhibitor selected by said screening method.
    Type: Application
    Filed: May 13, 2003
    Publication date: October 30, 2003
    Applicants: Chugai Seiyaku Kabushiki Kaisha, Trustees of Dartmouth College
    Inventors: Chang Ta-Yuan, Tatsuhiko Kodama, Takao Hamakubo, Yoshiki Kawabe
  • PTX3-gene expression inhibitor
    Publication number: 20030195167
    Abstract: A method for suppressing expression of PTX3 gene, which comprises administering an effective amount of a compound, which is represented by the following formula (1): 1
    Type: Application
    Filed: July 17, 2002
    Publication date: October 16, 2003
    Applicants: KOWA CO., LTD., Nissan Chemical Industies, Ltd.
    Inventors: Shigeru Morikawa, Akashi Izumi, Takao Hamakubo, Tatsuhiko Kodama
  • Screening method for SREBP pathway-specific inhibitors
    Patent number: 6602710
    Abstract: This invention provides a screening method for sterol regulatory element binding protein (SREBP) pathway-specific inhibitors using a mutant cultured cell, as well as therapeutic agents for hyperlipemia, arterial sclerosis, obesity or cancer containing an SREBP pathway-specific inhibitor selected by said screening method.
    Type: Grant
    Filed: August 27, 1998
    Date of Patent: August 5, 2003
    Assignees: Chugai Seiyaku Kabushiki Kaisha, Trustees of Dartmouth College
    Inventors: Ta-Yuan Chang, Tatsuhiko Kodama, Takao Hamakubo, Yoshiki Kawabe
  • Method for expressing and purifying proteins using budded baculovirus
    Publication number: 20030027131
    Abstract: The purpose of the present invention is to provide a method for efficiently expressing a protein in an active form by using baculovirus expression system wherein the protein is selected from a membrane-bound enzyme, a substrate of the membrane-bound enzyme, a membrane-bound enzyme activator, a membrane-bound transport protein, a channel protein, a membrane structural protein, a protein involved in adhesion, a protein involved in antigen presentation, or a protein involved in formation of high dimensional structure of a protein.
    Type: Application
    Filed: June 20, 2001
    Publication date: February 6, 2003
    Inventors: Takao Hamakubo, Tatsuhiko Kodama, Mineko Yamaguchi