Patents by Inventor Takao Kamahori

Takao Kamahori has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8198454
    Abstract: The present invention relates to an amide derivative of the formula (1), having a C5a receptor antagonistic action wherein each symbol is as defined in the specification. The above-mentioned amide derivative, an optically active form thereof and a pharmaceutically acceptable salt thereof are promising as an agent for the treatment or prophylaxis of diseases or syndromes caused by inflammation caused by C5a [e.g., autoimmune diseases such as rheumatism, systemic lupus erythematosus and the like, sepsis, adult respiratory distress syndrome, chronic obstructive pulmonary disease, allergic diseases such as asthma and the like, atherosclerosis, cardiac infarction, brain infarction, psoriasis, Alzheimer's disease and serious organ injury (e.g., pneumonia, nephritis, hepatitis and pancreatitis and the like) due to activation of leukocytes caused by ischemia reperfusion, trauma, burn, surgical invasion and the like].
    Type: Grant
    Filed: June 30, 2009
    Date of Patent: June 12, 2012
    Assignee: Mitsubishi Tanabe Pharma Corporation
    Inventors: Mitsuharu Nakamura, Takao Kamahori, Seigo Ishibuchi, Yoichi Naka, Hiroshi Sumichika, Katsuhiko Itoh
  • Patent number: 7855297
    Abstract: The present invention relates to an amide derivative of the formula (1), having a C5a receptor antagonistic action wherein each symbol is as defined in the specification. The above-mentioned amide derivative, an optically active form thereof and a pharmaceutically acceptable salt thereof are promising as an agent for the treatment or prophylaxis of diseases or syndromes caused by inflammation caused by C5a [e.g., autoimmune diseases such as rheumatism, systemic lupus erythematosus and the like, sepsis, adult respiratory distress syndrome, chronic obstructive pulmonary disease, allergic diseases such as asthma and the like, atherosclerosis, cardiac infarction, brain infarction, psoriasis, Alzheimer's disease and serious organ injury (e.g., pneumonia, nephritis, hepatitis and pancreatitis and the like) due to activation of leukocytes caused by ischemia reperfusion, trauma, burn, surgical invasion and the like].
    Type: Grant
    Filed: September 14, 2001
    Date of Patent: December 21, 2010
    Assignee: Mitsubishi Tanabe Pharma Corporation
    Inventors: Mitsuharu Nakamura, Takao Kamahori, Seigo Ishibuchi, Yoichi Naka, Hiroshi Sumichika, Katsuhiko Itoh
  • Publication number: 20100152261
    Abstract: A nitrogen-containing heterocyclic derivative represented by the following general formula (I), or a hydrate or solvate thereof, which has a selective antagonistic action on the muscarinic M3 receptor and causes reduced cardiac side effect and thus is safe, and has superior pharmacological efficacy and prolonged action even by inhalation administration, and a pharmaceutical composition comprising the compound and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: July 25, 2006
    Publication date: June 17, 2010
    Applicant: MITSUBISHI TANABE PHARMA CORPORATION
    Inventors: Hideyuki Aizawa, Makoto Seki, Jun-ichi Endoh, Minoru Tanaka, Naoto Fujie, Osamu Sakuma, Takao Kamahori
  • Publication number: 20100041656
    Abstract: The present invention relates to an amide derivative of the formula (1), having a C5a receptor antagonistic action wherein each symbol is as defined in the specification. The above-mentioned amide derivative, an optically active form thereof and a pharmaceutically acceptable salt thereof are promising as an agent for the treatment or prophylaxis of diseases or syndromes caused by inflammation caused by C5a [e.g., autoimmune diseases such as rheumatism, systemic lupus erythematosus and the like, sepsis, adult respiratory distress syndrome, chronic obstructive pulmonary disease, allergic diseases such as asthma and the like, atherosclerosis, cardiac infarction, brain infarction, psoriasis, Alzheimer's disease and serious organ injury (e.g., pneumonia, nephritis, hepatitis and pancreatitis and the like) due to activation of leukocytes caused by ischemia reperfusion, trauma, burn, surgical invasion and the like].
    Type: Application
    Filed: June 30, 2009
    Publication date: February 18, 2010
    Inventors: Mitsubaru NAKAMURA, Takao KAMAHORI, Seigo ISHIBUCHI, Yoichi NAKA, Hiroshi SUMICHIKA, Katsuhiko ITOH
  • Publication number: 20040138223
    Abstract: The present invention relates to an amide derivative of the formula (1), having a C5a receptor antagonistic action 1
    Type: Application
    Filed: May 8, 2003
    Publication date: July 15, 2004
    Inventors: Mitsuharu Nakamura, Takao Kamahori, Seigo Ishibuchi, Yoichi Naka, Hiroshi Sumichika, Katsuhiko Itoh