Patents by Inventor Takao MANDAI

Takao MANDAI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SCREENING METHOD
    Publication number: 20200182850
    Abstract: The present invention provides a useful and efficient screening method for finding a cholinergic muscarinic M1 receptor positive allosteric modulator (M1PAM) with reduced cholinergic side effects. The present invention also provides a method for treating Alzheimer's disease and the like, a method for reducing cholinergic side effects, and the like which use M1PAM selected by the screening method and having a low ? value, or the M1PAM and an acetylcholinesterase inhibitor.
    Type: Application
    Filed: May 17, 2018
    Publication date: June 11, 2020
    Inventors: Haruhide KIMURA, Yuu SAKO, Satoru MATSUDA, Yuji SHIMIZU, Emi KURIMOTO, Takao MANDAI, Maiko TANAKA