Abstract: The present disclosure provides a body fluid extract comprising micro RNA.

Abstract: The present disclosure provides a body fluid extract comprising micro RNA.

Abstract: The present disclosure provides a method for extracting a biomolecule. The present disclosure provides a method for extracting a cell-free DNA. The present disclosure provides a method for concentrating a DNA having a non-base pairing base. The present disclosure provides a method for concentrating a DNA having a low methylation modification level.

Abstract: The present disclosure provides a body fluid extract containing micro RNA. According to the present disclosure, an extract of body fluid containing any of the micro RNA described in data S1 or table 2, or in any of tables 4-1 to 4-15, is provided.

Abstract: The present disclosure provides a device for separating biomolecules comprising a substrate having a planar surface, nanowires disposed on at least a portion of the planar surface, and a fluid chamber formed to include at least a portion of the nanowires.

Abstract: Provided are a novel biomarker for a brain tumor and a method for using the same. A method for detecting a brain tumor, the method comprising the step of detecting specific miRNA as biomarker.

Abstract: The present invention provides a novel miRNA extraction method and a method for analyzing miRNA extracted by using said miRNA extraction method. According to the present invention, provided is, for example, a method for extracting miRNA from extracellular vesicles in a sample solution, by using a device capable of capturing extracellular vesicles, the miRNA extraction method comprising: an extracellular vesicle capturing step for capturing extracellular vesicles in a sample solution onto a device by bringing the sample solution and the device in contact with each other; and a miRNA extraction step for homogenizing the extracellular vesicles by bringing the device having captured the extracellular vesicles in contact with a homogenization liquid for extracellular vesicles to extract miRNA from the extracellular vesicle into the homogenization liquid.

Abstract: The present invention provides a novel miRNA extraction method and a method for analyzing miRNA extracted by using said miRNA extraction method. According to the present invention, provided is, for example, a method for extracting miRNA from extracellular vesicles in a sample solution, by using a device capable of capturing extracellular vesicles, the miRNA extraction method comprising: an extracellular vesicle capturing step for capturing extracellular vesicles in a sample solution onto a device by bringing the sample solution and the device in contact with each other; and a miRNA extraction step for homogenizing the extracellular vesicles by bringing the device having captured the extracellular vesicles in contact with a homogenization liquid for extracellular vesicles to extract miRNA from the extracellular vesicle into the homogenization liquid.

Abstract: In a method for analyzing samples involving the use of a device for analyzing samples, the device for analyzing samples includes at least a movement part through which a sample moves, and a measurement unit that is formed in a middle of the movement part and that measures a value of an ion current when the sample passes through the movement part. The analysis method includes at least a measurement step for measuring the value of the ion current when the sample passes through the movement part, and a determination step for determining a change over time in a quantity of ions from the value of the ion current measured in the measurement step. The quantity of ions includes a quantity of ions that have leaked from the sample during movement of the sample through the movement part.

Abstract: A device for biological material detection includes a substrate; a through-hole through which a biological material to be tested passes, the through-hole being formed in the substrate; a molecule that interacts with the biological material to be tested passing through, the molecule being formed in the through-hole; a first chamber member that forms, with at least the surface including the through-hole on one surface side of the substrate, a first chamber to be filled with electrolyte; and a second chamber member that forms, with at least the surface including the through-hole on the other surface side of the substrate, a second chamber to be filled with electrolyte. The biological material to be tested is identified by the waveform of the ion current (passage time, shape, etc.) when the biological material to be tested passes through the through-hole.

Abstract: Provided is a device for electrical measurement designed to be able to perform high sensitivity detection by reading not only changes in steady-state current, but also the occurrence of transient current, and an electrical measurement apparatus including the device for electrical measurement. The device for electrical measurement includes a substrate on which are formed at least a sample separation channel and a sample migration channel, as well as a sample measuring unit, with one end of the sample separation channel formed to connect to one end of the sample migration channel, and the sample measuring unit including a first measuring unit connected to the sample migration channel, and a second measuring unit connected to the sample migration channel from the reverse side to the first measuring unit.

Abstract: The present disclosure provides a body fluid extract comprising micro RNA.

Abstract: The present disclosure provides a device for separating biomolecules comprising a substrate having a planar surface, nanowires disposed on at least a portion of the planar surface, and a fluid chamber formed to include at least a portion of the nanowires.

Abstract: In a method for analyzing samples involving the use of a device for analyzing samples, the device for analyzing samples includes at least a movement part through which a sample moves, and a measurement unit that is formed in a middle of the movement part and that measures a value of an ion current when the sample passes through the movement part. The analysis method includes at least a measurement step for measuring the value of the ion current when the sample passes through the movement part, and a determination step for determining a change over time in a quantity of ions from the value of the ion current measured in the measurement step. The quantity of ions includes a quantity of ions that have leaked from the sample during movement of the sample through the movement part.

Abstract: A device for biological material detection includes a substrate; a through-hole through which a biological material to be tested passes, the through-hole being formed in the substrate; a molecule that interacts with the biological material to be tested passing through, the molecule being formed in the through-hole; a first chamber member that forms, with at least the surface including the through-hole on one surface side of the substrate, a first chamber to be filled with electrolyte; and a second chamber member that forms, with at least the surface including the through-hole on the other surface side of the substrate, a second chamber to be filled with electrolyte. The biological material to be tested is identified by the waveform of the ion current (passage time, shape, etc.) when the biological material to be tested passes through the through-hole.

Abstract: A transmission apparatus includes a first circuit, a second circuit, and a connector that couples the first circuit and the second circuit to each other, the first circuit includes a signal generation circuit that outputs an alternate current signal of a predetermined power at a frequency from a carrier frequency to three times the carrier frequency, and one of the first circuit and the second circuit includes a determination circuit that evaluates a fit state at the connector by determining whether the first circuit and the second circuit are fitted to each other via the connector based on the predetermined power and a power of the alternate current signal received by the determination circuit via the connector.

Abstract: Provided is a device for electrical measurement designed to be able to perform high sensitivity detection by reading not only changes in steady-state current, but also the occurrence of transient current, and an electrical measurement apparatus including the device for electrical measurement. The device for electrical measurement includes a substrate on which are formed at least a sample separation channel and a sample migration channel, as well as a sample measuring unit, with one end of the sample separation channel formed to connect to one end of the sample migration channel, and the sample measuring unit including a first measuring unit connected to the sample migration channel, and a second measuring unit connected to the sample migration channel from the reverse side to the first measuring unit.

Abstract: The communication apparatus includes a logical device, a wiring line, and a changing unit; the logical device is a programmable device; the wiring line supplies a voltage to the logical device; and the changing unit changes a frequency characteristic of the wiring line based on an operating characteristic obtained by monitoring of the operating characteristic of the logical device for operating by receiving supply of the voltage. According to this, occurrence of voltage drop can be suppressed even if a circuit configured in a programmable logical device is changed.

Abstract: In a part catalog creating system, a part table containing design change numbers respectively set for parts, and header numbers, part numbers, and quantity of the parts, each of which corresponds to the design change numbers, is created, and product number data that contains design change number of part used for manufacturing each product is created, and information that coincides with the product number data is selected from the part table, thereby creating a product number list. The product number list and images of parts corresponding to the product number list are combined and the part catalog data for each product number is output. Thus, the part catalog can be easily created without errors.

Abstract: In a part catalog creating system, a part table containing design change numbers respectively set for parts, and header numbers, part numbers, and quantity of the parts, each of which corresponds to the design change numbers, is created, and product number data that contains design change number of part used for manufacturing each product is created, and information that coincides with the product number data is selected from the part table, thereby creating a product number list. The product number list and images of parts corresponding to the product number list are combined and the part catalog data for each product number is output. Thus, the part catalog can be easily created without errors.