Abstract: Crystals of compounds represented by formula (I) having potential as drug substances for pharmaceuticals, as well as salts of compounds represented by formula (I) and their crystals.

Abstract: Provided is compound (3d) or a salt thereof, wherein the content of compound (IM-7) is 0.48 mass % or lower.

Abstract: The invention provides a production process allowing more high-yield and efficient synthesis of key intermediates (compound (2i) or a salt thereof, and compound (1g)) for production of E7090, which is useful as an FGFR inhibitor.

Abstract: Provided is a monoclonal antibody or a fragment thereof in which heavy-chain complementarity-determining regions (CDRs) 1 to 3 respectively consist of amino acid sequences of SEQ ID NOs: 2 to 4 and light-chain CDRs 1 to 3 respectively consist of amino acid sequences of SEQ ID NOs: 5 to 7; a monoclonal antibody or a fragment thereof in which heavy-chain CDRs 1 to 3 respectively consist of amino acid sequences obtained by deleting, substituting, or adding one or several amino acids in the amino acid sequences of SEQ ID NOs: 2 to 4 and light-chain CDRs 1 to 3 respectively consist of amino acid sequences obtained by deleting, substituting, or adding one or several amino acids in the amino acid sequences of SEQ ID NOs: 5 to 7, and which has binding properties to a KK-LC-1 protein; or a monoclonal antibody or a fragment thereof which competes with the monoclonal antibody or a fragment thereof in which the heavy-chain CDRs 1 to 3 respectively consist of the amino acid sequences of SEQ ID NOs: 2 to 4 and the light-ch

Abstract: The present disclosure relates to an image processing apparatus and an image processing method that can inhibit a decrease of coding efficiency. A transfer image that is a to-be-transferred image with a normal size including a downsized image obtained by size-reduction of a normal image whose image size is the normal size to a reduced size that is an image size smaller than the normal size is generated, and the generated transfer image is coded. Coded data is decoded, a transfer image that is a to-be-transferred image with a normal size including a downsized image obtained by size-reduction of a normal image whose image size is the normal size to a reduced size that is an image size smaller than the normal size is generated, and the downsized image is extracted from the generated transfer image.

Abstract: The present invention provides methods for the synthesis of ketones involving a Ni/Zr-mediated coupling reaction. The Ni/Zr-mediated ketolization reactions can be used in the synthesis of halichondrins (e.g., halichondrin A, B, C; homohalichondrin A, B, C; norhalichondrin A, B, C), and analogs thereof. Therefore, the present invention also provides synthetic methods useful for the synthesis of halichondrins, and analogs thereof. Also provided herein are compounds (i.e., intermediates) useful in the synthesis of halichondrins, and analogs thereof.

Abstract: The present invention provides methods for the synthesis of ketones involving a Ni/Zr-mediated coupling reaction. The Ni/Zr-mediated ketolization reactions can be used in the synthesis of halichondrins (e.g., halichondrin A, B, C; homohalichondrin A, B, C; norhalichondrin A, B, C), and analogs thereof. Therefore, the present invention also provides synthetic methods useful for the synthesis of halichondrins, and analogs thereof. Also provided herein are compounds (i.e., intermediates) useful in the synthesis of halichondrins, and analogs thereof. In particular, the present invention provides methods and compounds useful in the synthesis of compound of Formula (H3-A).

Abstract: A reference direction determination unit 44 detects, using an input image, a scene change, a flash scene, or a monotonous luminance variation section. In a case where an encoding target image is the scene change or flash scene, the reference direction determination unit 44 determines its mode as a fixed reference direction mode in which a reference direction in a screen is fixed uniformly. Further, in a case where the encoding target image is the monotonous luminance variation section, that is, a section where luminance of an entire screen monotonously increases or monotonously decreases, the reference direction determination unit 44 determines as the fixed reference direction mode in which the reference direction in the screen is fixed uniformly. A motion prediction/compensation unit 42 performs inter prediction processing according to a determination result of the reference direction determination unit 44, thereby enabling efficient encoding while suppressing deterioration of image quality.

Abstract: The present invention provides methods for the synthesis of ketones involving a Ni/Zr-mediated coupling reaction. The Ni/Zr-mediated ketolization reactions can be used in the synthesis of halichondrins (e.g., halichondrin A, B, C; homohalichondrin A, B, C; norhalichondrin A, B, C), and analogs thereof. Therefore, the present invention also provides synthetic methods useful for the synthesis of halichondrins, and analogs thereof. Also provided herein are compounds (i.e., intermediates) useful in the synthesis of halichondrins, and analogs thereof.

Abstract: A reference direction determination unit 44 detects, using an input image, a scene change, a flash scene, or a monotonous luminance variation section. In a case where an encoding target image is the scene change or flash scene, the reference direction determination unit 44 determines its mode as a fixed reference direction mode in which a reference direction in a screen is fixed uniformly. Further, in a case where the encoding target image is the monotonous luminance variation section, that is, a section where luminance of an entire screen monotonously increases or monotonously decreases, the reference direction determination unit 44 determines as the fixed reference direction mode in which the reference direction in the screen is fixed uniformly. A motion prediction/compensation unit 42 performs inter prediction processing according to a determination result of the reference direction determination unit 44, thereby enabling efficient encoding while suppressing deterioration of image quality.

Abstract: Provided is a monoclonal antibody or a fragment thereof in which heavy-chain complementarity-determining regions (CDRs) 1 to 3 respectively consist of amino acid sequences of SEQ ID NOs: 2 to 4 and light-chain CDRs 1 to 3 respectively consist of amino acid sequences of SEQ ID NOs: 5 to 7; a monoclonal antibody or a fragment thereof in which heavy-chain CDRs 1 to 3 respectively consist of amino acid sequences obtained by deleting, substituting, or adding one or several amino acids in the amino acid sequences of SEQ ID NOs: 2 to 4 and light-chain CDRs 1 to 3 respectively consist of amino acid sequences obtained by deleting, substituting, or adding one or several amino acids in the amino acid sequences of SEQ ID NOs: 5 to 7, and which has binding properties to a KK-LC-1 protein; or a monoclonal antibody or a fragment thereof which competes with the monoclonal antibody or a fragment thereof in which the heavy-chain CDRs 1 to 3 respectively consist of the amino acid sequences of SEQ ID NOs: 2 to 4 and the light-ch

Abstract: A satellite communication system and a data transmission method in satellite communication capable of improving the reliability of a system in satellite communication are provided. The satellite communication system of an embodiment includes a first communication device, a second communication device, and a slave station. The first communication device receives emergency information about disaster and transmits gate closing control data for issuing a command for closing a gate related to the disaster via a satellite. The second communication device is installed in a place geographically separated from the first communication device and receives emergency information about disaster and transmits gate closing control data for issuing an commands for closing a gate related to the disaster via a satellite. The slave station controls opening-closing of the gate on the basis of the gate closing control data received from the first communication device or the second communication device.

Abstract: A compound represented by the formula (I) or a salt thereof: wherein a ring Z is a 5 to 6-membered heteroaromatic ring having one or two heteroatoms in the ring; X1 is a hydrogen atom, a hydroxy group, a hydroxy C1-6 alkyl group, —B(OH)2, a boronate ester group, a cyclic boronate ester group, a boranyl group, a cyclic boranyl group, —BF3Mn1, —Sn(R12)(R13)(R14), a leaving group, a carboxy group, a formyl group, or —NR16R17; and X2 is a hydrogen atom or —CO2R18.

Abstract: The present disclosure relates to an image decoding device and method capable of suppressing an increase in an encoding or decoding load. The present disclosure includes: a decoding section configured to decode encoded data obtained by encoding image data for each of a plurality of certain areas obtained by dividing a picture using a plurality of blocks obtained by dividing the area as processing units, for each of the areas; a reordering section configured to reorder decoding results of the encoded data of the respective blocks obtained for the respective areas by the decoding section in a raster scan order of the entire picture; and a transform section configured to transform the decoding results of the respective blocks reordered in the raster scan order of the entire picture by the reordering section and generate decoded image data. The present disclosure can be applied to the image decoding device.

Abstract: Compounds represented by formulae (I) to (XXII) or pharmaceutically acceptable salts thereof:

Abstract: Compounds represented by formulae (I) to (XXII) or pharmaceutically acceptable salts thereof:

Abstract: A satellite communication system and a data transmission method in satellite communication capable of improving the reliability of a system in satellite communication are provided. The satellite communication system of an embodiment includes a first communication device, a second communication device, and a slave station. The first communication device receives emergency information about disaster and transmits gate closing control data for issuing a command for closing a gate related to the disaster via a satellite. The second communication device is installed in a place geographically separated from the first communication device and receives emergency information about disaster and transmits gate closing control data for issuing an commands for closing a gate related to the disaster via a satellite. The slave station controls opening-closing of the gate on the basis of the gate closing control data received from the first communication device or the second communication device.

Abstract: A compound represented by the formula (I) or a salt thereof: wherein a ring Z is a 5 to 6-membered heteroaromatic ring having one or two heteroatoms in the ring; X1 is a hydrogen atom, a hydroxy group, a hydroxy C1-6 alkyl group, —B(OH)2, a boronate ester group, a cyclic boronate ester group, a boranyl group, a cyclic boranyl group, —BF3Mn1, —Sn(R12)(R13)(R14), a leaving group, a carboxy group, a formyl group, or —NR16R17; and X2 is a hydrogen atom or —CO2R18.

Abstract: The present disclosure relates to an image decoding device and method capable of suppressing an increase in an encoding or decoding load. The present disclosure includes: a decoding section configured to decode encoded data obtained by encoding image data for each of a plurality of certain areas obtained by dividing a picture using a plurality of blocks obtained by dividing the area as processing units, for each of the areas; a reordering section configured to reorder decoding results of the encoded data of the respective blocks obtained for the respective areas by the decoding section in a raster scan order of the entire picture; and a transform section configured to transform the decoding results of the respective blocks reordered in the raster scan order of the entire picture by the reordering section and generate decoded image data. The present disclosure can be applied to the image decoding device.

Abstract: To efficiently use anchor information. When anchor information to be used in a decoding process of a target block to be decoded does not satisfy an identity condition with anchor information used for a previous block, anchor information of an anchor block corresponding to the target block to be decoded is acquired from an anchor information storage unit. When the identity condition is satisfied, the anchor information of the previous block is continuously used. A motion vector is calculated using the acquired anchor information or the anchor information to be continuously used. Motion compensation is performed based on the calculated motion vector, and prediction image data is generated.