Abstract: Described herein are novel anti-human Ig? antibodies, as well as methods for making the antibodies and using the antibodies to treat or prevent autoimmune disease.

Abstract: A secondary battery suppresses generation of wrinkle at the outer peripheral edge portion of a negative electrode plate due to expansion of a negative electrode active material layer with use. The secondary battery includes a positive electrode plate with a positive electrode active material layer disposed on a first current collector, and a negative electrode plate with a negative electrode active material layer having an area larger than an area of the positive electrode active material layer disposed on a second current collector. The negative electrode plate includes a facing portion facing the positive electrode active material layer and a non-facing portion. The negative electrode plate and a separator are bonded through a bonding layer. The bonding strength of a second bonding portion that bonds the non-facing portion to the separator is larger than the bonding strength of a first bonding portion that bonds the facing portion to the separator.

Abstract: [Problem] Provided is an anti-human Ig? antibody which crosslinks BCR and Fc?RIIb and has an immunosuppressive function more enhanced than that of an antibody in the prior art. [Means for Solution] An anti-human Ig? antibody comprising a heavy chain variable region comprising CDR1 consisting of the amino acid sequence of amino acid numbers 31 to 35 of SEQ ID NO: 2, CDR2 consisting of the amino acid sequence of amino acid numbers 50 to 65 of SEQ ID NO: 2, and CDR3 consisting of the amino acid sequence of amino acid numbers 98 to 108 of SEQ ID NO: 2, a light chain variable region comprising CDR1 consisting of the amino acid sequence of amino acid numbers 24 to 38 of SEQ ID NO: 4, CDR2 consisting of the amino acid sequence of amino acid numbers 54 to 60 of SEQ ID NO: 4, and CDR3 consisting of the amino acid sequence of amino acid numbers 93 to 101 of SEQ ID NO: 4, and a heavy chain constant region which is a human Ig?1 constant region having amino acid mutations of S239D, H268D, and L328W.

Abstract: A method of testing dynamic performances for a slider body of a thermally-assisted magnetic head includes: providing a slider body which is disconnected with a light source unit; removably mounting the slider body to a test head suspension assembly; keeping to provide a flat top beam to the slider body, the flat top beam being aligned with the optical waveguide, and a projection of an incident end of the optical waveguide being located within a light spot of the flat top beam; and testing the dynamic performance of the slider body. It can save the material cost and labor cost, and eliminate a precise optical alignment between an input light and an optical waveguide in the slider body to improve testing efficiency.

Abstract: An object of the present invention is to develop a biomarker for discriminating dementia, particularly, Alzheimer's disease and mild cognitive impairment which can progress to Alzheimer's disease, from other central nervous system diseases, or capable of determining a pathological condition of dementia, and provide a method for diagnosing dementia early and a method for determining a pathological condition of dementia, using the biomarker. A transferrin glycoprotein containing a glycan having at least one mannose at a non-reducing end or a transferrin fragment containing the glycan is used as a diagnostic marker for Alzheimer's disease.

Abstract: A communication system includes a source node and an end node of a first working path, a source node and an end node of a second working path, and a source node and an end node of a common path serving as a protection path shared by the first and second working paths. The source node of the common path transfers one of signals received from the source nodes of the first and second working paths to the common path, and the end node of the common path transmits the signal received through the common path to each of the end nodes of the first and second working paths.

Abstract: A current collector for a secondary battery (1) of the present invention includes a resin layer (2) having electrical conductivity, and an ion barrier layer (3) provided on the surface of the resin layer (2). The ion barrier layer (3) contains ion trapping particles (6) in which metal compounds (5) are provided on the surfaces of metal containing particles (4). The ion trapping particles (6) are continuously provided from an interface (7) between the resin layer (2) and the ion barrier layer (3) toward a surface (3a) of the ion barrier layer (3). Thus, the ion barrier layer (3) prevents from the entry of ions, so that the ion adsorption in the current collector (1) can be decreased.

Abstract: A method of testing dynamic performances for a slider body of a thermally-assisted magnetic head includes: providing a slider body which is disconnected with a light source unit; removably mounting the slider body to a test head suspension assembly; keeping to provide a flat top beam to the slider body, the flat top beam being aligned with the optical waveguide, and a projection of an incident end of the optical waveguide being located within a light spot of the flat top beam; and testing the dynamic performance of the slider body. It can save the material cost and labor cost, and eliminate a precise optical alignment between an input light and an optical waveguide in the slider body to improve testing efficiency.

Abstract: A light source unit for thermally-assisted magnetic head includes a support member and a light source attached on the support member via a solder, and the light source unit further includes a positioning structure formed between the support member and the light source for positioning the light source and the solder. The light source unit can maintain stable height control of the light source, prevent solder over flow and prevent the light source from shifting and moving during the bonding process.

Abstract: There is provided means for identifying whether or not users of mobile information terminals (mobile information terminals) in a network service are the same as or different from one another. Location information 151, 152 is obtained by the mobile information terminals 121 each comprising a GPS function, and location information 151 representing a resident state at a home, a workplace or a school is obtained when the mobile information terminal users 123 carry their respective mobile information terminals 121. The location information 151 is specific to each user, and therefore, is used as identification information to differentiate the users to thereby allow identification of the users of the mobile information terminals by a management server 110.

Abstract: A coupling structure of optical components has a first optical component, a second optical component and a coupling solder layer. The first optical component has a lensed fiber, a first holder holding the lensed fiber and a first metal layer formed on a first connecting end face of the first holder. The second optical component has a waveguide, a second holder holding the waveguide and a second metal layer formed on a second connecting end face of the second holder. The coupling solder layer is in direct contact with both of the first metal layer and the second metal layer, and formed with solder.

Abstract: A coupling structure of optical components has a first optical component, a second optical component and a coupling solder layer. The first optical component has a lensed fiber, a first holder holding the lensed fiber and a first metal layer formed on a first connecting end face of the first holder. The second optical component has a waveguide, a second holder holding the waveguide and a second metal layer formed on a second connecting end face of the second holder. The coupling solder layer is in direct contact with both of the first metal layer and the second metal layer, and formed with solder.

Abstract: The present invention provides a non-aqueous electrolyte secondary battery with various improved battery characteristics and a method for manufacturing such a non-aqueous electrolyte secondary battery. In the present invention, the battery manufacturing method includes accommodating and sealing a flat battery element (4) in which a positive electrode plate (41) and a negative electrode plate (42) stacked together via a separator (43), together with a non-aqueous electrolyte including a surplus electrolyte and at least one kind of electrolyte additive, in a laminate film exterior member (5), and then, subjecting the thus-assembled battery (1) to charging operation including at least initial charging in a state where a pressure is applied to a flat surface of the battery element from the outside of the exterior member (5).

Abstract: A non-aqueous electrolyte secondary battery can efficiently discharge the gas generated to the outside of the electrode and exhibits a low decrease in battery capacity even when used for a long period of time in the case of using an aqueous binder as the binder of a negative electrode active material. The non-aqueous electrolyte secondary battery has a positive electrode active material layer is formed on a surface of a positive electrode current collector, a negative electrode active material layer is formed on a surface of a negative electrode current collector, and a separator, wherein the density of the negative electrode active material layer is from 1.3 to 1.6 g/cm3, the negative electrode active material layer contains an aqueous binder, and the surface center line average roughness (Ra) of a surface on a separator side of the negative electrode active material layer is from 0.5 to 1.0 ?m.

Abstract: A lubricant composition improves a performance of reducing a formation of compressor deposit. The lubricant composition also ensures low temperature properties of the lubricant composition. The lubricant composition includes 14 mass % or more of a fraction having a boiling point of 500° C. to 550° C. and 5 mass % or more of a fraction having a boiling point of over 550° C.

Abstract: A transmission apparatus includes a plurality of blades mounted in a juxtaposed relationship in an open rack and including a first blade and a second blade disposed next to the first blade, wherein the second blade includes: a sensor, and a processor coupled to the sensor and configured to: receive first position information indicating a mounting position of the first blade from the first blade, measure a distance between the first blade and the second blade using the sensor, and calculate second position information indicating a mounting position of the second blade based on the first position information and the measured distance.

Abstract: A non-aqueous electrolyte secondary battery, when using an aqueous binder as a binder for a negative electrode active material, effectively exhausts the gas generated from an electrode, and thus, even when using it for a long period of time, a decrease in battery capacity is low. The non-aqueous electrolyte secondary battery includes a positive electrode active material layer on a surface of a positive electrode current collector, a negative electrode active material layer comprising an aqueous binder on a surface of a negative electrode current collector, a separator for maintaining an electrolytic solution, and a gas releasing means for releasing a gas generated within the power generating element to an extra space inside of the outer casing, and in which the ratio value of a volume of the extra space to a volume of pores included in the power generating element is 0.5 to 1.0.