Patents by Inventor Takashi Ishibashi
Takashi Ishibashi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20130317116Abstract: This invention provides an external skin preparation with high safety aimed at wrinkle improvement and wrinkle prevention. Specifically, the invention relates to an external skin preparation comprising, as an active ingredient, a carotenoid.Type: ApplicationFiled: February 2, 2012Publication date: November 28, 2013Applicant: JX NIPPON OIL & ENERGY CORPORATIONInventors: Takashi Maoka, Takashi Ishibashi
-
Publication number: 20120068562Abstract: A rotary electrical apparatus includes a housing, a stator including a center axis inclined by a predetermined angle relative to a horizontal direction in a case where the housing is fixed to a mounting member, a rotor, and an oil stored at a lower side within the housing relative to the center axis and functioning as at least one of a cooling oil, a lubricating oil, and an operating oil. The housing includes an oil inlet port and an oil discharge port allowing the oil to be discharged once a predetermined amount of the oil is stored within the housing, the oil discharge port being displaced from a first oil passage on which the oil supplied from the oil inlet port moves downward along an inner peripheral wall surface of the housing in a state where the housing is held so that the center axis is arranged to be horizontal.Type: ApplicationFiled: September 14, 2011Publication date: March 22, 2012Applicant: AISIN SEIKI KABUSHIKI KAISHAInventors: Shigetaka ISOGAI, Keiichiro KAWASHIMA, Takashi ISHIBASHI, Masahiro OMURA
-
Publication number: 20120029088Abstract: This invention provides a highly safe anti-anxiety composition that can be used for treatment or prevention of anxiety disorders. Such anti-anxiety composition comprises, as an active ingredient, a carotenoid.Type: ApplicationFiled: July 21, 2011Publication date: February 2, 2012Applicant: JX NIPPON OIL & ENERGY CORPORATIONInventors: Hideaki HARA, Atsushi OOYAGI, Takashi ISHIBASHI
-
Patent number: 7220430Abstract: The present invention is to provide a sustained release preparation comprising a drug-containing core substance and a multilayered coating layer covering the core substance, wherein all adjacent layers in the multilayered coating layer contain mutually different hydrophobic organic compound-water-soluble polymer mixtures; and, a method of producing a sustained release preparation, having a multilayered coating layer in which adjacent layers contain different hydrophobic organic compound-water-soluble polymer mixtures, which comprises spray-coating a solution containing a hydrophobic organic compound-water-soluble polymer mixture onto a drug-containing core substance, continuing to spray-coat a solution containing a different hydrophobic organic compound-water-soluble polymer mixture onto the resulting coating layer, and repeating this step.Type: GrantFiled: January 26, 2001Date of Patent: May 22, 2007Assignee: Tanabe Seiyaku Co., Ltd.Inventors: Takashi Ishibashi, Kengo Ikegami, Keigo Nagao, Hiroyuki Yoshino, Masakazu Mizobe
-
Publication number: 20040137061Abstract: The present invention provides a process for producing an orally fast disintegrating preparation containing functional particles, which comprises filling in a mold an aqueous dispersion containing (a) a dispersant showing a dispersion maintaining ratio of about 75% or more and a viscosity of about 100 mPa.s or less at 25° C. in case of being contained homogeneously in water at 1% by weight, (b) a water-soluble saccharide, and (c) functional particles; and then removing water; and an orally fast disintegrating preparation containing functional particles, which comprises (a) a dispersant showing a dispersion maintaining ratio of 75% or more and a viscosity of 100 mPa.s or less at 25° C. in case of being contained homogeneously in water at 1% by weight, (b) a water-soluble saccharide, and (c) functional particles.Type: ApplicationFiled: December 5, 2003Publication date: July 15, 2004Inventors: Takashi Ishibashi, Keigo Nagao, Kosuke Kiyomizu
-
Patent number: 6692768Abstract: The present invention discloses an efficient preparation method of spherical fine particles containing a drug for an easily-swallowed, controlled-release preparation comprising the production of drug-containing spherical fine particles (mean particle size: 60-200 &mgr;m) by adding a binder solution to a mixture containing an excipient powder having the property of retaining solvent (and preferably having a mean length of the long axis of 40 &mgr;m or less) and a drug powder (preferably having a mean length of the long axis of 50 &mgr;m or less), followed by high-speed mixing granulation.Type: GrantFiled: April 26, 2001Date of Patent: February 17, 2004Assignee: Tanabe Seiyaku Co., Ltd.Inventors: Takashi Ishibashi, Keigo Nagao, Kengo Ikegami, Hiroyuki Yoshino, Masakazu Mizobe
-
Patent number: 6692769Abstract: The present invention discloses sustained release particles having a mean particle size of 300 &mgr;m, or less, comprising a drug-containing core substance coated with a mixed coating of a hydrophobic organic compound-water-insoluble polymer, which prevents sticking during compression molding when producing oral sustained release tablets, a preparation method of those sustained release particles, and a preparation method of tablets using those sustained release particles.Type: GrantFiled: April 26, 2001Date of Patent: February 17, 2004Assignee: Tanabe Seiyaku Co., Ltd.Inventors: Takashi Ishibashi, Keigo Nagao, Kengo Ikegami, Hiroyuki Yoshino, Masakazu Mizobe
-
Patent number: 6638534Abstract: A preparation capable of releasing a medicinal substance at a targeted site in the intestine, wherein the preparation dose not releases medicinal substance in endogastri at all, but can quickly release a medicinal substance when it reaches the desired site in the intestine after a certain period of time from discharge of the preparation from the stomach, and wherein a core material containing a medicinal substance is coated with a mixed film of a hydrophobic organic compound—an enteric polymer.Type: GrantFiled: January 29, 2001Date of Patent: October 28, 2003Assignee: Tanabe Seiyaku Co., Ltd.Inventors: Takashi Ishibashi, Hiroaki Kubo, Hiroyuki Yoshino, Masakazu Mizobe
-
Publication number: 20030012815Abstract: The present invention is to provide a sustained release preparation comprising a drug-containing core substance and a multilayered coating layer covering the core substance, wherein all adjacent layers in the multilayered coating layer contain mutually different hydrophobic organic compound-water-soluble polymer mixtures; and, a method of producing a sustained release preparation, having a multilayered coating layer in which adjacent layers contain different hydrophobic organic compound-water-soluble polymer mixtures, which comprises spray-coating a solution containing a hydrophobic organic compound-water-soluble polymer mixture onto a drug-containing core substance, continuing to spray-coat a solution containing a different hydrophobic organic compound-water-soluble polymer mixture onto the resulting coating layer, and repeating this step.Type: ApplicationFiled: July 25, 2002Publication date: January 16, 2003Inventors: Takashi Ishibashi, Kengo Ikegami, Keigo Nagao, Hiroyuki Yoshino, Masakazu Mizobe
-
Patent number: 6309666Abstract: A pharmaceutical preparation in the form of a coated capsule which can release contents of a capsule at a lower part of the digestive tract comprising (a) a hard capsule containing at least an acidic substance, (b) a polymer film soluble at low pH which is formed on a surface of said hard capsule, and (c) an enteric coating film which is formed on a surface of said polymer film soluble at low pH. According to the pharmaceutical preparation of the present invention, any kind of a medicament can be delivered to any desired site between the upper part of the small intestine and the lower part of the large intestine in the digestive tract by controlling the amount of polymer(s) used for the polymer film soluble at low pH and/or by selecting the kind of the polymer film soluble at low pH and/or the acidic substance without any complicated requirements for each medicament.Type: GrantFiled: July 15, 1996Date of Patent: October 30, 2001Assignee: Tanabe Seiyaku Co., Ltd.Inventors: Harumi Hatano, Takahiro Ito, Takashi Ishibashi, Hiroyuki Yoshino, Masakazu Mizobe
-
Patent number: 5393332Abstract: Herein disclosed is a method for preparing a nuclear-substituted salicylic acid or a metal salt thereof represented by the following general formula (1): ##STR1## [wherein R.sub.1 and R.sub.2 each represents a t-butyl group, a t-amyl group, a t-octyl group, an isononyl group or an isododecyl group, provided that at least one of R.sub.1 and R.sub.2 represents an isononyl group or an isododecyl group; M represents a hydrogen atom or a metal atom; and n is the atomic valency of the metal atom M] which comprises the step of subjecting, to a Kolbe-Schmitt reaction, an alkali metal salt of a nuclear-substituted phenol represented by the following general formula (2): ##STR2## [wherein R.sub.1 and R.sub.2 are the same as those defined above] in which 100 to 50% of the alkali metal salt is potassium salt and 0 to 50% thereof is sodium salt, in a substantially water-insoluble solvent as a reaction medium.Type: GrantFiled: December 9, 1993Date of Patent: February 28, 1995Assignees: Sanko Kaihatsu Kagaku Kenkyusho, Kanzaki Paper Manufacturing Co., Ltd.Inventors: Toranosuke Saito, Takashi Ishibashi, Eiji Kawabata, Masato Tanaka, Toshio Kimura
-
Patent number: 5208480Abstract: A dynamic latch circuit which is fabricated in a semiconductor integrated circuit comprises a first circuit such as a clocked inverter and a second circuit such as an inverter. The first and second circuits are connected by a holding line. In the semiconductor integrated circuit, at least three interconnection layers are provided on a semiconductor substrate to be insulated by insulating layers, such that the holding line is provided as the secondly highest interconnection layer, and an output line of the second circuit is provided as the uppermost interconnection layer to be positioned on the straight upper side of the holding line. For this structure, a coupling capacitance which is formed between the holding line and a through line connected to a third circuit and provided as the uppermost interconnection layer is decreased.Type: GrantFiled: August 28, 1991Date of Patent: May 4, 1993Assignee: NEC CorporationInventor: Takashi Ishibashi
-
Patent number: 5118443Abstract: A developer comprising at least one polyvalent metal salt of a nuclear substituted salicylic acid of the following general formula is provided. ##STR1## In the formula, R.sub.1 represents an alkyl group having from 1 to 12 carbon atoms, R.sub.2 represents a hydrogen atom or an alkyl group having from 1 to 12 carbon atoms, R.sub.3 represents a hydrogen atom or a methyl group provided that at least one of R.sub.1 and R.sub.2 is a secondary butyl group, a secondary hexyl group, an isohexyl group, a secondary octyl group, an isononyl group, a secondary decyl group, a secondary dodecyl group or an isododecyl group and the total number of the carbon atoms in R.sub.1, R.sub.2 and R.sub.3 is from 9 to 18, M is a polyvalent metal atom, and m is a valence of M. An aqueous dispersion containing the developer and a method for preparing the developer are also described.Type: GrantFiled: January 22, 1991Date of Patent: June 2, 1992Assignees: Sanko Kaihatsu Kagaku Kenkyusho, Kanzaki Paper Manufacturing Co., Ltd.Inventors: Toranosuke Saito, Takashi Ishibashi, Tomoharu Shiozaki, Tetsuo Shiraishi
-
Patent number: 5041604Abstract: A process for producing a high quality di(aryloxy)alkane with a high yield by the use of readily commercially available materials, without using any particular solvent or agent and by means of a simple operation and a general apparatus is provided, which process comprises subjecting a halogenated alkane of the formula (II)X--A--Y (II)wherein X and Y each represent a halogen atom and A represents a lower alkylene group, and a phenol of the formula (III) ##STR1## wherein R.sub.1 to R.sub.5 each are same or different, represent hydrogen, halogen, lower alkyl, lower alkoxy, carboxylic acid salt, acyl or nitro group, and may form a ring in conjunction of two adjacent groups,to condensation reaction in the presence of an alkali in an aqueous medium to form a di(aryloxy)alkane of the formula (I) ##STR2## and is characterized (i) by carrying out the condensation reaction in a molar ratio of the compound of the formula (II): the phenol of the formula (III): the alkali in terms of monovalent base of 1:1.5 to 3.0:1.Type: GrantFiled: June 20, 1990Date of Patent: August 20, 1991Assignee: Sanko Kaihatsu Kagaku KenkyushoInventors: Toranosuke Saito, Masakatu Kitani, Takashi Ishibashi
-
Patent number: 5019548Abstract: A heat sensitive recording material comprising a substrate and a recording layer thereon incorporating a colorless or light-colored basic dye and a color acceptor reactive with the dye to form a color when contacted therewith, the recording material being characterized in that, as the color acceptor is used at least one compound selected from the group consisting of 4-hydroxy-4'-isopropyloxydiphenylsulfone, 4,4'-(1,3-dimethylbutylidene) bisphenol, 4,4'-(1-phenylethylidene)bisphenol, 4,4'-(p-phenylenediisopropylidene)bisphenol and 4,4'-(m-phenylenediisopropylidene) bisphenol, and to the recording layer is added at least one of a heat-fusible substance represented by the formula [I] ##STR1## wherein X is hydrogen atom, halogen atom, C.sub.1.about.4 alkyl or C.sub.1.about.4 alkoxy.Type: GrantFiled: August 24, 1989Date of Patent: May 28, 1991Assignees: Kanzaki Paper Manufacturing Co., Ltd., Sanko Kaihatsu Kagaku Kenkyusho CorporationInventors: Toshitake Suzuki, Fumio Seyama, Shuki Okauchi, Toranosuke Saito, Masakatu Kitani, Takashi Ishibashi
-
Patent number: 4542395Abstract: Novel phenolic compounds useful as a color developer suitable for satisfying the quality requirements of heat-sensitive recording materials are provided, which compounds are expressed by the general formula ##STR1## wherein R.sub.1 represents an alkyl group or a cycloalkyl group and R.sub.2 represents hydrogen atom or an alkyl group; and also heat-sensitive recording materials usable in a broad application field are provided, which recording materials are provided with a heat-sensitive recording layer composed mainly of a colorless basic dye and the above compounds as a color developer by which the dye forms colors, overlaid on a substrate.Type: GrantFiled: November 5, 1984Date of Patent: September 17, 1985Assignees: Sanko Kaihatsu Kagaku Kenkyusho, Kanzai Paper Manufacturing Company Ltd.Inventors: Toranosuke Saito, Masakatu Kitani, Takashi Ishibashi, Naoto Arai, Takeshi Murakami, Toshitake Suzuki
-
Patent number: 4542042Abstract: A process for preparing free-flowing microcapsules by taking advantage of the phase-separation of ethylcellulose in cyclohexane is disclosed. In this process, a hydrocarbon compound which is soluble in cyclohexane and have a molecular weight of 150 to 3,000 and a solubility parameter (.delta., at 25.degree. C.) of 7 to 10 (cal/cm.sup.3).sup.1/2 is used as the phase-separation-inducing agent.Type: GrantFiled: July 1, 1983Date of Patent: September 17, 1985Assignee: Tanabe Seiyaku Co., Ltd.Inventors: Masayoshi Samejima, Goichi Hirata, Takashi Ishibashi
-
Patent number: D517543Type: GrantFiled: February 25, 2005Date of Patent: March 21, 2006Assignee: Hitachi, Ltd.Inventors: Isshu Nakajima, Yukinobu Maruyama, Koji Suso, Takashi Ishibashi, Shinichi Urano
-
Patent number: D490422Type: GrantFiled: February 3, 2003Date of Patent: May 25, 2004Assignee: Hitachi, Ltd.Inventors: Yoshihiro Iwama, Yuichiro Kota, Minoru Ikeda, Takashi Ishibashi
-
Patent number: RE36321Abstract: In a heat-sensitive recording material incorporating a colorless or pale-colored basic dye and a color acceptor which is reactive with the basic dye to form a color when contacted therewith, the recording material characterized in that at least one compound represented by the formula ?I! is contained in a heat-sensitive recording layer ##STR1## wherein X is --O-- or --COO--, R.sub.1 to R.sub.4 are each hydrogen atom, alkyl having 1 to 8 carbon atoms, aryl having 6 to 10 carbon atoms, aralkyl having 7 to 9 carbon atoms, chlorine atom, acetyl, propionyl, methoxy, methylthio, methoxycarbonyl, cyano, nitro or cyclohexenyl, substituents R.sub.1 and/or R.sub.2 or substituents R.sub.3 and R.sub.4 may link together to form aromatic ring(s), n is an integer of 1 to 10.Type: GrantFiled: June 20, 1988Date of Patent: September 28, 1999Assignees: Kansaki Paper Manufacturing Co., Ltd., Sanko Kaihatsu Kagaku Kekyusho CorporationInventors: Toshitake Suzuki, Naoto Arai, Shoji Aoyagi, Toranosuke Saito, Masakatu Kitani, Takashi Ishibashi