Abstract: There is provided a measurement system that measures the volume of a drug solution that fills a needle-shaped recess of a mold. A measurement unit of the measurement system measures respective heights of a plurality of measurement points which are stored in a storage unit and are preset on a plane parallel to the mold, in a direction orthogonal to the plane. A surface shape calculation unit calculates a three-dimensional shape of the surface of the drug solution on the basis of the heights of the plurality of measurement points measured by the measurement unit. A volume calculation unit calculates the volume of the drug solution that fills the needle-shaped recess on the basis of the three-dimensional shape of the surface of the drug solution calculated by the surface shape calculation unit and the shape of the needle-shaped recess of the mold.

Abstract: Provided are a microneedle array imaging device, a microneedle array imaging method, a microneedle array inspection device, and a microneedle array inspection method which enable inspection of a microneedle array with high accuracy based on an obtained image. A microneedle array 1 is imaged from a side of a surface on which microneedles 2 are arranged by irradiating a surface on a side opposite to the surface on which the microneedles 2 are arranged with parallel light as illumination light. At this time, the surface is irradiated with the illumination light under conditions in which an incident angle ? of light onto a bottom surface 2a of the microneedle 2 is 90??° or greater and an incident angle ? of light onto a side surface 2b of the microneedle 2 is less than a critical angle ?. In this manner, a state in which almost no light is emitted from a tip portion of the microneedle 2 can be generated.

Abstract: A measurement method measuring a volume of a drug in each needle-shaped recess of a mold includes: acquiring a reference surface height that is a height between a reference surface determined in advance with respect to a first surface on the side on which a drug is filled in the mold or a second surface opposite to the first surface, and the second surface; acquiring a first detection result by detecting a measurement wave emitted from a drug surface according to incidence of the measurement wave on the drug in the needle-shaped recess; detecting a first height between the reference surface and the drug surface; detecting a second height from the second surface to the drug surface based on the reference surface height and the first height; and calculating a volume of the drug based on the second height and a known shape of the needle-shaped recess.

Abstract: A measurement system that measures an amount of a drug solution in each needle-shaped recess of a mold in which a plurality of needle-shaped recesses are formed, or an amount of a drug after drying the drug solution, includes: a first detection unit that detects position information regarding each needle-shaped recess in a state where the drug solution does not fill the needle-shaped recess; a first measurement unit that measures a shape of the needle-shaped recess; a second detection unit that detects position information regarding a surface of the drug solution or the drug; a second measurement unit that measures a shape of the surface of the drug solution or the drug; and a calculation unit that calculates a volume of the drug solution or the drug based on the shape of the needle-shaped recess and the shape of the surface of the drug solution or the drug.

Abstract: In an imaging device, and an operation method and an imaging control program of the imaging device, it is possible to acquire a captured image by suppressing a decrease in image quality caused by droplets attached to a container. Before a heating unit heats a container in which an observation target is housed, and an imaging unit performs main imaging for the observation target housed in the container, a pre-measurement unit measures brightness of light transmitting through or reflected by the container. In a case where a value of the brightness measured by a pre-measurement unit is smaller than a standard value set in advance, the control unit causes the imaging unit to perform the main imaging after droplets attached to the container are removed by increasing a temperature of the container by the heating unit or by keeping the temperature of the container constant by the heating unit.

Abstract: An imaging apparatus includes: an imaging apparatus main body for imaging an observation target contained in a container; and a liquid droplet adhesion determination unit that acquires pattern information of liquid droplets adhering to a bottom surface on an outer side of the container based on an image of the observation target imaged by the imaging apparatus main body and determines whether or not the liquid droplets adhere to the bottom surface based on the pattern information. In a case where the liquid droplet adhesion determination unit determines that the liquid droplets adhere to the bottom surface on the outer side of the container, the imaging apparatus main body images the observation target again after performing liquid droplet removal processing.

Abstract: The present invention provides a measurement method, a measurement device, and a program capable of non-destructively measuring a volume of an aqueous solution of a drug in each needle-like recess of a mold with high accuracy. A measurement method according to a preferred embodiment of the present invention includes a measurement wave intensity acquisition step of acquiring, for each needle-like recess, an intensity of a measurement wave transmitted through a drug in a needle-like recess, absorbed by the drug by an amount according to a distance by which the measurement wave is transmitted through the drug, and emitted from the drug; and a volume acquisition step of acquiring a volume for each needle-like recess on the basis of the intensity of the measurement wave for each needle-like recess acquired in the measurement wave intensity acquisition step.

Abstract: Provided are a microneedle array imaging device, a microneedle array imaging method, a microneedle array inspection device, and a microneedle array inspection method which enable inspection of a microneedle array with high accuracy based on an obtained image. A microneedle array 1 is imaged from a side of a surface on which microneedles 2 are arranged by irradiating a surface on a side opposite to the surface on which the microneedles 2 are arranged with parallel light as illumination light. At this time, the surface is irradiated with the illumination light under conditions in which an incident angle ? of light onto a bottom surface 2a of the microneedle 2 is 90??° or greater and an incident angle ? of light onto a side surface 2b of the microneedle 2 is less than a critical angle ?. In this manner, a state in which almost no light is emitted from a tip portion of the microneedle 2 can be generated.

Abstract: An imaging apparatus includes: an imaging apparatus main body for imaging an observation target contained in a container; and a liquid droplet adhesion determination unit that acquires pattern information of liquid droplets adhering to a bottom surface on an outer side of the container based on an image of the observation target imaged by the imaging apparatus main body and determines whether or not the liquid droplets adhere to the bottom surface based on the pattern information. In a case where the liquid droplet adhesion determination unit determines that the liquid droplets adhere to the bottom surface on the outer side of the container, the imaging apparatus main body images the observation target again after performing liquid droplet removal processing.

Abstract: The present invention provides a measurement method, a measurement device, and a program capable of non-destructively measuring a volume of an aqueous solution of a drug in each needle-like recess of a mold with high accuracy. A measurement method according to a preferred embodiment of the present invention includes a measurement wave intensity acquisition step of acquiring, for each needle-like recess, an intensity of a measurement wave transmitted through a drug in a needle-like recess, absorbed by the drug by an amount according to a distance by which the measurement wave is transmitted through the drug, and emitted from the drug; and a volume acquisition step of acquiring a volume for each needle-like recess on the basis of the intensity of the measurement wave for each needle-like recess acquired in the measurement wave intensity acquisition step.

Abstract: A measurement system that measures an amount of a drug solution in each needle-shaped recess of a mold in which a plurality of needle-shaped recesses are formed, or an amount of a drug after drying the drug solution, includes: a first detection unit that detects position information regarding each needle-shaped recess in a state where the drug solution does not fill the needle-shaped recess; a first measurement unit that measures a shape of the needle-shaped recess; a second detection unit that detects position information regarding a surface of the drug solution or the drug; a second measurement unit that measures a shape of the surface of the drug solution or the drug; and a calculation unit that calculates a volume of the drug solution or the drug based on the shape of the needle-shaped recess and the shape of the surface of the drug solution or the drug.

Abstract: There is provided a measurement system that measures the volume of a drug solution that fills a needle-shaped recess of a mold. A measurement unit of the measurement system measures respective heights of a plurality of measurement points which are stored in a storage unit and are preset on a plane parallel to the mold, in a direction orthogonal to the plane. A surface shape calculation unit calculates a three-dimensional shape of the surface of the drug solution on the basis of the heights of the plurality of measurement points measured by the measurement unit. A volume calculation unit calculates the volume of the drug solution that fills the needle-shaped recess on the basis of the three-dimensional shape of the surface of the drug solution calculated by the surface shape calculation unit and the shape of the needle-shaped recess of the mold.

Abstract: A measurement method measuring a volume of a drug in each needle-shaped recess of a mold includes: acquiring a reference surface height that is a height between a reference surface determined in advance with respect to a first surface on the side on which a drug is filled in the mold or a second surface opposite to the first surface, and the second surface; acquiring a first detection result by detecting a measurement wave emitted from a drug surface according to incidence of the measurement wave on the drug in the needle-shaped recess; detecting a first height between the reference surface and the drug surface; detecting a second height from the second surface to the drug surface based on the reference surface height and the first height; and calculating a volume of the drug based on the second height and a known shape of the needle-shaped recess.

Abstract: White light and excitation light are applied to an internal body part. An electronic endoscope captures a normal image of the internal body part irradiated with the white light, and a special image of autofluorescence emitted from living body tissue of the internal body part irradiated with the excitation light. An object distance detector detects an object distance between a CCD and an inspection area of the internal body part based on the normal image. A binning processing section applies a binning process to the special image. There are two types of binning processes, i.e. an intensity adjustment process and a resolution adjustment process. In the intensity adjustment process, the binning number is increased with increase in the object distance. In the resolution adjustment process, the binning number is decreased with increase in the object distance. Which process to perform is determined by operation on a processing type selector.

Abstract: Provided is an image capturing system comprising an irradiating section that sequentially irradiates an observed position with a plurality of types of irradiation light having different polarizations; a polarization filter section that includes a plurality of polarization filter units, which each include a plurality of returned polarized light filters that each pass light having a different polarization, the polarization filter section passing returned light from the observed position having each of the plurality of polarizations; and a light receiving section that receives the returned light passed by the polarization filter section having each of the plurality of polarizations.

Abstract: Provided is an unevenness detecting apparatus comprising a determining section that determines a polarization state of returned light obtained from radiated light; an uneven portion judging section that judges whether an uneven portion is present based on the polarization state determined by the determining section; a convex/concave identifying section that identifies whether the uneven portion is convex or concave based on image data, captured by an image capturing element, of the uneven portion; and an output section that outputs information identifying whether the uneven portion is convex or concave.

Abstract: White light and excitation light are applied to an internal body part. An electronic endoscope captures a normal image of the internal body part irradiated with the white light, and a special image of autofluorescence emitted from living body tissue of the internal body part irradiated with the excitation light. An object distance detector detects an object distance between a CCD and an inspection area of the internal body part based on the normal image. A binning processing section applies a binning process to the special image. There are two types of binning processes, i.e. an intensity adjustment process and a resolution adjustment process. In the intensity adjustment process, the binning number is increased with increase in the object distance. In the resolution adjustment process, the binning number is decreased with increase in the object distance. Which process to perform is determined by operation on a processing type selector.

Abstract: An optical system includes a light sending section that sends light to an object having a scattering medium and a lower medium positioned below the scattering medium, where the scattering medium scatters light and the lower medium feeds back polarized light in response to light incident thereon, a light receiving section that receives (i) light that is sent from the light sending section and then scattered by the scattering medium and (ii) light from the lower medium, and a thickness calculating section that calculates a thickness of the scattering medium, by referring to at least one of a non-polarization component and a polarization component of the light received by the light receiving section.

Abstract: There is provided an optical device including a plurality of first phasors having substantially the same phase delaying axis as each other; and a plurality of second phasors having substantially the same phase delaying axis as each other in a direction different from that of the first phasors and providing a phase difference substantially the same as that provided by the first phasors, in which the plurality of first phasors and the plurality of second phasors are arranged on substantially the same face, a density of the first phasors is substantially the same as a density of the second phasors, and a spatial distribution of the density of the first phasors and a spatial distribution of the density of the second phasors are substantially uniform.

Abstract: Provided is an image capturing apparatus comprising a plurality of first light receiving elements that are arranged on substantially the same plane and that each receive light of a first color component from a subject; a plurality of second light receiving elements that are arranged on substantially the same plane and with a higher surface density than the plurality of first light receiving elements, and that each receive light of a second color component from the subject; and a polarizing section that blocks polarized light components from the subject except for a first polarized light component so that first-polarized-light receiving elements, which are a portion of the plurality of second light receiving elements, receive the first polarized light component from the subject, the first-polarized-light receiving elements transmitting the light from the subject to be received by the plurality of first light receiving elements.