Patents by Inventor Takashi Nakatsuka
Takashi Nakatsuka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12172135Abstract: A hollow fiber porous membrane includes polyethersulfone or polysulfone. The hollow fiber porous membrane has an inner diameter from 300-600 ?m, a thickness from 70-200 ?m, a molecular weight cut-off of 10000 or lower, and a plurality of pores having a pore diameter from 0.1-0.5 ?m throughout an outer surface; and a bulging rate of less than 5%. For 20 or more of the hollow fiber porous membranes, after a membrane thickness in a cross section of each one of the hollow fiber porous membranes in the width direction is measured at randomly selected 10 or more locations, an average membrane thickness is calculated based on 200 or more locations in total, and the bulging rate is calculated by a formula below: Bulging Rate (%)=(location numbers where the membrane thickness as measured exceeded 1.3 times the average membrane thickness)/(membrane thickness measurement numbers)×100.Type: GrantFiled: September 18, 2019Date of Patent: December 24, 2024Assignees: DAICEN MEMBRANE-SYSTEMS LTD., NIPRO CORPORATIONInventors: Shuji Nakatsuka, Takashi Sunohara, Toshinari Takahashi
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Publication number: 20240287685Abstract: A pickling apparatus for pickling a strip of metal being conveyed is equipped with: a pickling tank for storing an acid solution; a surrounding part disposed in the pickling tank so as to surround the strip immersed in the acid solution in the pickling tank; and an oxidant supply part for supplying a liquid oxidant toward an inside of the surrounding part.Type: ApplicationFiled: July 9, 2021Publication date: August 29, 2024Applicant: PRIMETALS TECHNOLOGIES JAPAN, LTD.Inventors: Naohiko MATSUDA, Takashi NAKANO, Yuki MAEHASHI, Shinji NAMBA, Masashi YOSHIKAWA, Kosei TSUJI, Takahiro YAGI, Ryusuke NAKATSUKA
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Patent number: 8293781Abstract: A compound, or its salt, or a solvate thereof having a cPLA2 inhibiting activity having the formula (I): or a pharmaceutical composition, cPLA2 inhibitor and inhibitors of various lipid mediator production containing the same as active ingredients.Type: GrantFiled: March 28, 2008Date of Patent: October 23, 2012Assignee: Daiichi Sankyo Company, LimitedInventors: Toshiyuki Tomoo, Takashi Nakatsuka, Yasuhiro Hayashi, Toyoko Katayama
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Publication number: 20100113777Abstract: A compound, or its salt, or a solvate thereof having a cPLA2 inhibiting activity having the formula (I): or a pharmaceutical composition, cPLA2 inhibitor and inhibitors of various lipid mediator production containing the same as active ingredients.Type: ApplicationFiled: March 28, 2008Publication date: May 6, 2010Applicant: Asubio Pharma Co., Ltd.Inventors: Toshiyuki Tomoo, Takashi Nakatsuka, Yasuhiro Hayashi, Toyoko Katayama
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Patent number: 6867297Abstract: An azetidinone derivative represented by the general formula (1) (wherein OR1 is a protected hydroxyl group; R2 is a substituted or unsubstituted alkyl group, a substituted or unsubstituted alkenyl group or a substituted or unsubstituted aromatic group) is reacted with an ester compound represented by the formula (2) (wherein CO2R3 is an esterified carboxyl group; X and Y are the same or different and represent individually a substituted or unsubstituted alkyl group, a substituted or unsubstituted alkenyl group, a substituted or unsubstituted aralkyl group, a substituted or unsubstituted aryl group, a substituted or unsubstituted alkylthio group, a substituted or unsubstituted alkenylthio group, a substituted or unsubstituted aralkylthio group, a substituted or unsubstituted arylthio group, a substituted or unsubstituted alkyloxy group, a substituted or unsubstituted alkenyloxy group, a substituted or unsubstituted aralkyloxy group, a substituted or unsubstituted aryloxy group, a substituted or unsubsType: GrantFiled: October 26, 1998Date of Patent: March 15, 2005Assignee: Daiichi Suntory Pharma Co., Ltd.Inventors: Masaji Ishiguro, Takashi Nakatsuka, Rie Tanaka, Tetsuo Shimamoto, Takuro Yoshida
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Publication number: 20050004092Abstract: A penem derivative represented by the following formula (I): wherein R1 represents a substituted or unsubstituted alkyl group, a substituted or unsubstituted alkenyl group, a substituted or unsubstituted aralkyl group, a substituted or unsubstituted aryl group, a substituted or unsubstituted alkylthio group, a substituted or unsubstituted alkenylthio group, a substituted or unsubstituted aralkylthio group, a substituted or unsubstituted arylthio group, a substituted or unsubstituted heterocyclic group, a substituted or unsubstituted heterocyclic thio group, a substituted or unsubstituted acylthio group, a mercapto group or a hydrogen atom, and R2 represents a hydrogen atom or a carboxyl-protecting group; or a pharmacologically acceptable salt thereof. The compound (I) exhibits strong antibacterial activities, and especially, shows strong activities against MRSA.Type: ApplicationFiled: April 26, 2004Publication date: January 6, 2005Applicant: DAIICHI SUNTORY PHARMA CO., LTD.Inventors: Masaji Ishiguro, Takashi Nakatsuka, Rie Tanaka, Koshi Namikawa, Shinsuke Matsuki
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Patent number: 6734180Abstract: An inhibitor of NF-&kgr;B comprising as an active ingredient an indan derivative represented by the general formula (I) or a salt thereof.Type: GrantFiled: March 22, 2000Date of Patent: May 11, 2004Assignee: Daiichi Suntory Pharma Co., Ltd.Inventors: Yoichi Nunokawa, Takashi Nakatsuka, Masayuki Saitoh, Keiichi Abe
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Patent number: 6684131Abstract: A robot controller capable of minimizing an increase in the tact time during work, reducing changes in joint axes of the robot, thereby providing the structure with long mechanical life. The robot controller i) stores a plurality of movement data formed of amount and time for movement; ii) checks whether a movement of a robot has acceleration exceeding a predetermined level by calculation on the basis of the stored movement data; iii) increases the time for movement of the corresponding movement data, the preceding and following data to the movement data, if the calculation indicates over-acceleration; and iv) controls the robot according to the time-increased movement data.Type: GrantFiled: June 25, 2002Date of Patent: January 27, 2004Assignee: Matsushita Electric Industrial Co., Ltd.Inventors: Atsumi Hashimoto, Takashi Nakatsuka, Masahiro Ohto
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Patent number: 6570355Abstract: An object of the present invention is to provide a control apparatus for a robot in which the work efficiency is improved in the whole robot peripheral system including the robot, and in which considering the increase in the consciousness of safety such as the standardization of safety apparatuses, both the reliability of the safety circuit of the control apparatus for a robot and the ensuring of the safety are improved. By connecting, to peripheral devices outside the robot, each intermediate output signal line for extracting the operation signal or the emergency stop signal of each of the plurality of switches each assigned to a factor causing the stop of the robot, a factor to cause the stop of the robot body alone can be distinguished from a factor to cause the stop of both the robot body and the peripheral devices.Type: GrantFiled: April 2, 2001Date of Patent: May 27, 2003Assignee: Matsushita Electric Industrial Co., Ltd.Inventors: Kunitoshi Morita, Kei Aimi, Masahiro Ohto, Kazunori Matsumoto, Takashi Nakatsuka
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Publication number: 20030014156Abstract: A robot controller capable of minimizing an increase in the tact time during work, reducing changes in joint axes of the robot, thereby providing the structure with long mechanical life. The robot controller i) stores a plurality of movement data formed of amount and time for movement; ii) checks whether a movement of a robot has acceleration exceeding a predetermined level by calculation on the basis of the stored movement data; iii) increases the time for movement of the corresponding movement data, the preceding and following data to the movement data, if the calculation indicates over-acceleration; and iv) controls the robot according to the time-increased movement data.Type: ApplicationFiled: June 25, 2002Publication date: January 16, 2003Inventors: Atsumi Hashimoto, Takashi Nakatsuka, Masahiro Ohto
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Publication number: 20010027352Abstract: An object of the present invention is to provide a control apparatus for a robot in which the work efficiency is improved in the whole robot peripheral system including the robot, and in which considering the increase in the consciousness of safety such as the standardization of safety apparatuses, both the reliability of the safety circuit of the control apparatus for a robot and the ensuring of the safety are improved.Type: ApplicationFiled: April 2, 2001Publication date: October 4, 2001Inventors: Kunitoshi Morita, Kei Aimi, Masahiro Ohto, Kazunori Matsumoto, Takashi Nakatsuka
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Patent number: 6084374Abstract: The controller comprises (a) an interpolation calculator for dividing move data of a robot arm tip position into each sample period, the data fed from a position teaching section, (b) a load inertia calculator, (c) a gravity torque calculator, (d) acceleration and deceleration (A & D) time calculator for calculating an optimum A & D time by using the load inertia calculated by the load inertia calculator and the gravity torque calculated by the gravity torque calculator, (e) an A & D processor for providing an A & D process to move data of each sample time calculated by the interpolation calculator based on the A & D time calculated by the A & D time calculator, and (f) position controllers for controlling each motor based on the move data processed by the A & D processor. The A & D time is calculated with the following equation:T=.alpha..multidot.(J.sub.m +J.sub.L)/(T.sub.m -T.sub.L).multidot.Vwhere: V=desirable speed, J.sub.m =motor inertia, J.sub.L =load inertia, T.sub.m =motor torque, T.sub.Type: GrantFiled: September 24, 1998Date of Patent: July 4, 2000Assignee: Matsushita Electric Industrial Co., Ltd.Inventors: Takashi Nakatsuka, Atsumi Hashimoto, Yasushi Mukai, Kazuhito Ochiai
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Patent number: 6051569Abstract: A carbapenem derivative represented by the following formula (I), ##STR1## wherein R.sub.1 represents a hydrogen atom, a substituted or unsubstituted aryl group, or a substituted or unsubstituted heterocyclic group, R.sub.2 indicates a hydrogen atom or a protective group for a carboxyl group, and R.sub.3 is a methyl group or an ethyl group; or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising this carbapenem derivative or a salt thereof as an active ingredient. The carbapenem derivative exhibits a wide and strong antimicrobial activity, particularly a strong antimicrobial activity against MRSA. An intermediate compound for preparing the carbapenem derivative is also disclosed.Type: GrantFiled: August 15, 1997Date of Patent: April 18, 2000Assignee: Suntory LimitedInventors: Masaji Ishiguro, Takashi Nakatsuka, Hidekazu Inoue
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Patent number: 6049009Abstract: A method for producing an optically active trans-vinylsulfide alcohol having the formula: ##STR1## wherein R.sup.1 represents an alkyl group or an aryl group, comprising the step of reducing a trans-vinylsulfide ketone with a borane reducing agent in the presence of an optically active oxazaborolidine and an additive.Type: GrantFiled: June 30, 1997Date of Patent: April 11, 2000Assignee: Suntory LimitedInventors: Kazuto Sekiuchi, Masahiro Imoto, Masaji Ishiguro, Takashi Nakatsuka, Rie Tanaka, Hidekazu Inoue
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Patent number: 5993044Abstract: An acceleration generated when a tool tip of a robot moves straightly or turns a teaching point inward, is suppressed under a predetermined maximum acceleration so that the tool tip moves smoothly.Type: GrantFiled: August 22, 1997Date of Patent: November 30, 1999Assignee: Matsushita Electric Industrial Co., Ltd.Inventors: Masahiro Ohto, Hisashi Kinoshita, Takashi Nakatsuka, Yoshinori Nishida
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Patent number: 5986424Abstract: A control system which comprises a reduction gear unit containing gears, a motor being disposed on an input side of said reduction gear unit, a sensor for detecting a turning angle of said motor, and control means for inputting output from said sensor and controlling turning of said motor. The control system further includes gear output angle variation estimation means for estimating a gear output angle variation of said reduction gear unit based on the motor turning angle. An angle transmission error is estimated based on the motor turning angle, whereby load tip locus accuracy can be improved without lowering responsivity of the control system.Type: GrantFiled: February 20, 1998Date of Patent: November 16, 1999Assignee: Matsushita Electric Industrial Co., Ltd.Inventors: Takashi Nakatsuka, Atsumi Hashimoto, Yasushi Mukai, Kiyoshi Ohishi
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Patent number: 5885981Abstract: Antibiotic penem compounds are represented by the following formula: ##STR1## wherein R represents a group of the general formula: ##STR2## in which R.sub.1 is a hydrogen atom or linear or branched C.sub.1 --C.sub.6 alkyl group, R.sub.2 is a particular substituted or unsubstituted alkyl, aryl or aralkyl group, n is an integer of 1-6, Y is a 5- or 6-membered heterocyclic aliphatic group having 1 or 2 oxygen atoms in the ring thereof, and Z is a specific 5-substituted 2-oxo-1,3-dioxolen-4-yl group. Antibiotic compositions for oral administration are also described.Type: GrantFiled: June 6, 1995Date of Patent: March 23, 1999Assignee: Suntory LimitedInventors: Hiromitsu Iwata, Takashi Nakatsuka, Rie Tanaka, Masaji Ishiguro
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Patent number: 5830889Abstract: Antibiotic penem compounds are represented by the following formula: ##STR1## wherein R represents a group of the general formula: ##STR2## in which R.sub.1 is a linear or branched C.sub.1 -C.sub.6 alkyl group, R.sub.2 is a particular substituted or unsubstituted alkyl, aryl or aralkyl group, n is an integer of 1-6, Y is a 5- or 6-membered heterocyclic aliphatic group having 1 or 2 oxygen atoms in the ring thereof, and Z is a specific 5-substituted 2-oxo-1,3-dioxolen-4-yl group. Antibiotic compositions for oral administration are also described.Type: GrantFiled: February 19, 1993Date of Patent: November 3, 1998Assignee: Suntory LimitedInventors: Hiromitsu Iwata, Takashi Nakatsuka, Rie Tanaka, Masaji Ishiguro
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Patent number: 5821362Abstract: Method of desilylating a silylether compound by reacting a silylether compound of the general formula (I): ##STR1## or a salt thereof with an amine hydrogen fluoride salt or a pyridine hydrogen fluoride salt in an organic solvent to produce a compound of the general formula (IV): ##STR2## According to this method, silylether compounds that are labile under strong acidic or basic conditions can be desilylated efficiently using inexpensive reagents.Type: GrantFiled: December 27, 1995Date of Patent: October 13, 1998Assignee: Suntory LimitedInventors: Akira Kaneko, Tsutomu Kaku, Masaji Ishiguro, Takashi Nakatsuka
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Patent number: 5703068Abstract: Antibiotic penem compounds are represented by the following formula: ##STR1## wherein R represents a group of the following formula: ##STR2## in which R.sub.1 is a linear or branched, C.sub.1 -C.sub.6 alkyl group, R.sub.2 is a particular substituted or unsubstituted alkyl, aryl or aralkyl group, n is an integer of 1 or 2, and R.sub.3 represents a specific substituted or unsubstituted alkyl, aryl or aralkyl group. Antibiotic compositions for oral administration are also described.Type: GrantFiled: February 19, 1993Date of Patent: December 30, 1997Assignee: Suntory LimitedInventors: Hiromitsu Iwata, Takashi Nakatsuka, Rie Tanaka, Masaji Ishiguro