Abstract: A sanitary napkin comprises an absorbing body. The absorbing body includes a fluid-permeable top sheet, a fluid-impermeable back sheet, and an absorber arranged between the top sheet and the back sheet. The napkin comprises a cover sheet for covering the surface of the top sheet. A circumferential edge region of the cover sheet is joined to the absorbing body. A plurality of flaps for fixing the absorbing body to underwear are sectionalized by a sectionalizing line in the central region of the cover sheet. At the time of use, the flaps are folded in the folding regions and are expanded so as to be fixed to the underwear. The flaps include a front flap, a rear flap, a left flap and a right flap. A leakage-preventing region is formed on the cover sheet between the folding regions and the circumferential edge region.

Abstract: A sanitary napkin comprises an absorbing body. The absorbing body includes a fluid-permeable top sheet, a fluid-impermeable back sheet, and an absorber arranged between the top sheet and the back sheet. The napkin comprises a cover sheet for covering the surface of the top sheet. A circumferential edge region of the cover sheet is joined to the absorbing body. A flap for fixing the absorbing body to underwear is sectionalized by a sectionalizing line in the central region of the cover sheet. At the time of use, the flap is folded in a folding region and is expanded so as to be fixed to the underwear. A mark is provided on the surface of the cover sheet positioned substantially at the center of the absorbing body to facilitate the positioning of the absorbing body relative to clothing. The mark is colored, but a surrounding portion surrounding the mark is not colored.

Abstract: A sanitary napkin comprises an absorbing body. The absorbing body includes a fluid-permeable top sheet, a fluid-impermeable back sheet, and an absorber arranged between the top sheet and the back sheet. The napkin comprises a cover sheet for covering the surface of the top sheet. A circumferential edge region of the cover sheet is joined to the absorbing body. A plurality of flaps for fixing the absorbing body to underwear are sectionalized by a sectionalizing line in the central region of the cover sheet. At the time of use, the flaps are folded in the folding regions and are expanded so as to be fixed to the underwear. The flaps include a front flat and a rear flap that expand in the back-and-forth direction, and a left flap and a right flap that expand in the right-and-left direction.

Abstract: A wiring clip 1 includes: an attaching portion 10 configured to be overlapped with a wiring harness; a locking portion 11 extended vertically from the attaching portion 10 and configured to be locked in a hole provided on a panel; and a pressing portion 12 configured to press the panel in a direction away from the attaching portion 10 when the locking portion 11 is locked in the hole. The pressing portion 12 includes: an inclined portion 19 continued to the attaching portion 10 and inclined with respect to both a vertically extending direction of the locking portion 11 from the attaching portion 10 and a longitudinal direction of the wiring harness overlapped with the attaching portion 10; and a parallel portion 20 continued to the inclined portion 19 and extended parallel to the locking portion 11 from the inclined portion 19.

Abstract: A sanitary napkin (101) has a liquid-permeable top sheet (102), a liquid-impermeable back sheet (103), and an absorber (104) mounted between the top sheet (102) and the back sheet (103) and capable of absorbing bodily fluid. The sanitary napkin (101) also has insertion holes (107) provided on opposite sides in the lateral direction (W) of the sanitary napkin (101) so as to extend in the longitudinal direction (L) of the sanitary napkin (101), and long members (106) are inserted through the insides of the insertion holes (107). Each of the insertion holes (107) has an opening (108) located on the front end side (Fr) and also has a fixing portion (112) located on the rear end side (Ba). The long members (106) each have a long portion (111) inserted through the inside of the insertion holes (107) and also have a draw-out portion (109) led out from the openings (108) to the outside of the insertion holes (107). The rear ends of the long portion (111) are fixed to the fixing portion (112).

Abstract: An individually wrapped absorbent article 1 comprising an absorbent article 2 and a wrapping sheet 3, said absorbent article having a shape being relatively long in a longitudinal direction having a liquid-pervious top-sheet, a liquid-impervious back-sheet and a liquid-retentive absorbent core, on one hand, and said wrapping sheet 3 having a shape being also relatively long in the longitudinal direction arranged to cover the back-sheet of the absorbent article 2, on the other hand, so as to be folded back in the longitudinal direction of the absorbent article 2 by a predetermined fold length dimension L1, respectively, with the top-sheet inside. The wrapping sheet 3 is provided with a first display region 33 having a predetermined length dimension L3 as measured from one end of the wrapping sheet 3 in the longitudinal direction and the length dimension L3 of the first display region 33 is set to be smaller than the fold length dimension L1.

Abstract: An absorbent article that realizes favorable erection of gathers and excels in transversal leakage preventing effects. There is disclosed a vertically long absorbent article comprising a surface layer with surface sheet (2), a backside layer with backside sheet (3), an absorbent layer with absorbent body (4) interposed therebetween and a pair of gathers (5,5) formed of a sheetlike member (9) so as to have a hollow on both the side areas of the surface layer in the longitudinal direction thereof. The pair of gathers (5,5) in the state of having a three-dimensional configuration part (10) wherein the sheetlike member (9) makes a convex on the external surface side of the absorbent article in the thickness direction thereof are joined to the surface layer and/or backside layer by a junction portion (11) provided so as to extend in the longitudinal direction of the absorbent article. The three-dimensional configuration part (10) is provided so as to construct a hollow.

Abstract: An absorbent article that is favorable in the erection stability of gathers and excels in transversal leakage preventing effects. A pair of gathers of an absorbent article has a three-dimensional configuration part. The three-dimensional configuration part is formed so as to construct a hollow. A first junction edge portion is formed on the inward side in the width direction of the absorbent article and a second junction edge portion is provided on the outward side in the width direction of the absorbent article. The first junction edge portion is located on the area of the surface layer on which the absorbent body is disposed. The second junction edge portion, in at least the area where the pair of wings are disposed, is located on the area of the surface layer and/or backside layer more outward in the width direction than the periphery of the absorbent body.

Abstract: An absorbent article that prevents a discharged matter from leaking out, and also prevents a wearer's sensation of wearing a sanitary napkin from worsening is provided. The absorbent article of the present invention includes a liquid-permeable surface sheet, a liquid-permeable back sheet, an absorbent body disposed between the surface sheet and the back sheet, and an intermediate portion disposed between the surface sheet and the absorbent body. The absorbent part 4 includes an absorbent body center portion and an absorbent body posterior portion continuously formed on a posterior side in the longitudinal direction D of the absorbent body center portion. The intermediate portion includes a first intermediate sheet disposed between the surface sheet and the absorbent body center portion and a second intermediate sheet disposed between the surface sheet and at least the absorbent body posterior portion.

Abstract: An absorbent article that prevents a discharged matter from leaking out, and also prevents a wearer's sensation of wearing a sanitary napkin from worsening is provided. The absorbent article of the present invention includes a liquid-permeable surface sheet, a liquid-permeable back sheet, an absorbent body disposed between the surface sheet and the back sheet, and an intermediate portion disposed between the surface sheet and the absorbent body. The absorbent part 4 includes an absorbent body center portion and an absorbent body posterior portion continuously formed on a posterior side in the longitudinal direction D of the absorbent body center portion. The intermediate portion includes a first intermediate sheet disposed between the surface sheet and the absorbent body center portion and a second intermediate sheet disposed between the surface sheet and at least the absorbent body posterior portion.

Abstract: The invention relates to compounds represented by the general formula [I] ##STR1## [wherein Ar means an aryl group or a heteroaryl group which may have a substitutive group selected from a group consisting of a halogen atom, a lower alkyl group and a lower alkoxy group; R.sup.1 means a C.sub.3 -C.sub.6 cycloalkyl group which is substitutable with a fluorine atom; R.sup.2 and R.sup.4 mean hydrogen atoms, groups represented by --(A.sup.1).sub.m --NH--B or the like; R.sup.3 and R.sup.5 mean hydrogen atoms, C.sub.1 -C.sub.6 aliphatic hydrocarbon groups or the like which are substitutable with a lower alkyl group(s); n means 0 or 1; and X means an oxygen atom or a sulfur atom].Compounds according to the invention, since they not only have potent selective antagonistic activity against muscarinic M.sub.

Abstract: In the production of fluorine-containing 1,4-disubstituted piperidine derivatives by the reaction of a carboxylic acid of formula where Ar represents aryl or heteroaryl and R.sup.10 represents C.sub.3 -C.sub.6 cycloalkyl in which up to 4 hydrogen atoms are substituted with fluorine or C.sub.3 -C.sub.6 cycloalkyl having 1 to 2 protected or unprotected hydroxyl or oxo groups, or a reactive derivative thereof, with a piperidine derivative of formula [IV] as defined in the specification, especially useful results are obtained using 4-amino-1-(6-aminopyridin-2-ylmethyl)piperidine or a salt thereof, e.g., trihydrochloride, as the piperidine derivative.

Abstract: Novel fluorine-containing 1,4-disubstituted piperidine derivatives, represented by general formula ?I! ##STR1## such as, for example, (2R)-N-?1-(6-aminopyridin-2-ylmethyl)piperidin-4-yl!-2-?(1R)-3,3-difluoroc yclopentyl!-2-hydroxy-2-phenylacetamide or pharmaceutically acceptable salt thereof, are potent and selective antagonists for muscarinic M.sub.3 receptors with little side effects. The compounds of formula ?I! exhibit excellent oral activity, duration of activity and pharmacolkinetics. They are useful for treatment and prophylaxis of respiratory diseases, such as chronic obstructive pulmonary diseases; urinary diseases, such as urinary incontinence; and digestive diseases, such as irritable bowel syndrome, and motion sickness.

Abstract: A compound of the formula (I) or its pharmaceutically acceptable salt or ester: ##STR1## wherein each of ##STR2## which are the same or different, is an aryl group or a heteroaromatic ring group; A is a C.sub.3-8 linear saturated or unsaturated aliphatic hydrocarbon group which may have substituent(s) selected from the group consisting of a lower alkyl group, a hydroxyl group, a lower alkoxy group, a carboxyl group, an aryl group and an aralkyl group; Q is a single bond or a group of the formula --CO--O--, --O--CO--, --CH.sub.2 CH.sub.2 --, --CH.dbd.CH--, --OCH.sub.2 --, --SCH.sub.2 --, --CH.sub.2 O-- or --CH.sub.2 S--; each of R.sup.1, R.sup.2, R.sup.3 and R.sup.4 which are the same or different, is a hydrogen atom, a halogen atom, a lower alkyl group, a hydroxyl group, a lower alkoxy group, or an aryl or heteroaromatic ring group which may have substituent(s) selected from the group consisting of a halogen atom, a lower alkyl group and a lower alkoxy group; each of R.sup.5, R.sup.6 and R.sup.

Abstract: This invention provides novel 1,4-di-substituted piperidine derivatives of the general formula ?I! ##STR1## and the pharmaceutically acceptable salts thereof, wherein: Ar represents a phenyl group or a five- or six-membered heteroaromatic group having one or two hetero atoms selected from the group consisting of an oxygen atom, a sulfur atom and a nitrogen atom in which one or two optional hydrogen atoms on the ring may be replaced by substituent groups selected from the group consisting of a halogen atom and a lower alkyl group;R.sup.1 represents a cycloalkyl group of 3 to 6 carbon atoms or a cycloalkenyl group of 3 to 6 carbon atoms;R.sup.2 represents a saturated or unsaturated aliphatic hydrocarbon radical of 5 to 15 carbon atoms; andX represents O or NH.These compounds have selective antagonistic activity against the muscarinic M.sub.3 receptors and can hence be used safely with a minimum of side effects.

Abstract: A compound of the formula (I) or its pharmaceutically acceptable salt or ester: ##STR1## wherein each of the substituents are herein defined.

Abstract: A compound of the formula (I) or its pharmaceutically acceptable salt or ester: ##STR1## and intermediates thereof.

Abstract: A compound of the formula (I) or its pharmaceutically acceptable salt or ester: ##STR1## wherein each of the substituents are herein defined.

Abstract: Substituted heterocyclic derivatives represented by the formula (I) ##STR1## wherein R, R.sup.1, R.sup.2, R.sup.3, R.sup.4, Q.sup.1, Q.sup.2, Q.sup.3, Q.sup.4, X and Y are as defined, including, specifically, the compound (E)-3-[3-[3-(2-methoxymethyl-8,8-dimethyl-4-nonen-6-ynyl)phenoxymethyl]phe nyl]thiophene, exhibit squalene epoxidase inhibiting activity and are useful in the treatment or prophylaxis of hypercholesterolemia, hyperlipidemia and arteriosclerosis.

Abstract: Substituted amine derivatives represented by the general formula ##STR1## wherein Q is --C--D--E--F--G--M-- or --N--H--I--J--K--L-- [C, D, E, F, G, H, I, J, K and L are each O, S, a carbonyl group, --CHR.sup.a --, --R.sup.b .dbd. or --NR.sup.c -- (R.sup.a, R.sup.b and R.sup.c are each H or a lower alkyl group), M and N are each an aromatic ring of 5-6 members optionally having a halogen, OH, LN, a lower alkyl group or a lower alkoxy group, provided that L is not O, S, or --NR.sup.c --]; R is a heterocyclic ring of 5-6 members; R.sup.1 is H, a lower alkyl group, a lower haloalkyl group, a lower alkenyl group, a lower alkynyl group or a cycloalkyl group; R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6 and R.sup.7 are each H, a halogen or a lower alkyl group or two of them denote a single bond; R.sup.8 and R.sup.9 are each F, CF.sub.3 or a lower alkyl group or are a cycloalkane in combination thereof; and R.sup.10 is H, F, CF.sub.3 an acetoxy group, a lower alkyl group or a lower alkoxy group.