Abstract: A headlight determination apparatus includes a camera device, a target light recognition device, and a changing device. The camera device captures an image ahead of a vehicle at a predetermined frame rate. The target light recognition device recognizes target light from the image captured by the camera device. The changing device changes a wavelength of headlight of the vehicle by using a predetermined period slower than the predetermined frame rate. When the wavelength of the headlight is different from a wavelength of the target light and/or when a period of the wavelength of the headlight does not match a period of the wavelength of the target light, the target light recognition device recognizes that there is target light other than the headlight in front of the vehicle and controls light distribution of the headlight when there is target light other than the headlight in front of the vehicle.

Abstract: The application relates to a compound of Formula (I): or a pharmaceutically acceptable salt, hydrate, solvate, prodrug, stereoisomer, or tautomer thereof, which modulates the activity of BTK, a pharmaceutical composition comprising a compound of Formula (I), and a method of treating or preventing a disease in which BTK plays a role.

Abstract: The application relates to a compound of Formula (I): or a pharmaceutically acceptable salt, hydrate, solvate, prodrug, stereoisomer, or tautomer thereof, which modulates the activity of BTK, a pharmaceutical composition comprising a compound of Formula (I), and a method of treating or preventing a disease in which BTK plays a role.

Abstract: The application relates to a compound of Formula (I): or a pharmaceutically acceptable salt, hydrate, solvate, prodrug, stereoisomer, or tautomer thereof, which modulates the activity of BTK, a pharmaceutical composition comprising a compound of Formula (I), and a method of treating or preventing a disease in which BTK plays a role.

Abstract: A quinolone synthetic antibacterial agent having excellent properties as a medicine is provided, which has strong antibacterial activity not only to Gram-negative bacteria but also to Gram-positive cocci that have low sensitivity to quinolone antibacterial agents, and which exhibits high safety and excellent pharmacokinetics. A compound represented by the formula (I) or a salt thereof, or a hydrate thereof. Specifically, a quinolone derivative of the formula (I) wherein substituents R6 and R7 taken together with the carbon atoms to which they are bonded form a cyclic structure which may contain an oxygen atom as a ring constituent atom, the cyclic structure forming a 5-4, 5-5, or 5-6 fused bicyclic pyrrolidinyl substituent, the substituent being bonded to a quinolone mother skeleton Q containing a pyridobenzoxazine structure.

Abstract: A quinolone synthetic antibacterial agent having excellent properties as a medicine is provided, which has strong antibacterial activity not only to Gram-negative bacteria but also to Gram-positive cocci that have low sensitivity to quinolone antibacterial agents, and which exhibits high safety and excellent pharmacokinetics. A compound represented by the formula (I) or a salt thereof, or a hydrate thereof. Specifically, a quinolone derivative of the formula (I) wherein substituents R6 and R7 taken together with the carbon atoms to which they are bonded form a cyclic structure which may contain an oxygen atom as a ring constituent atom, the cyclic structure forming a 5-4, 5-5, or 5-6 fused bicyclic pyrrolidinyl substituent, the substituent being bonded to a quinolone mother skeleton Q containing a pyridobenzoxazine structure.

Abstract: A quinolone synthetic antibacterial agent having excellent properties as a medicine is provided, which has strong antibacterial activity not only to Gram-negative bacteria but also to Gram-positive cocci that have low sensitivity to quinolone antibacterial agents, and which exhibits high safety and excellent pharmacokinetics. A compound represented by the formula (I) or a salt thereof, or a hydrate thereof. Specifically, a quinolone derivative of the formula (I) wherein substituents R6 and R7 taken together with the carbon atoms to which they are bonded form a cyclic structure which may contain an oxygen atom as a ring constituent atom, the cyclic structure forming a 5-4, 5-5, or 5-6 fused bicyclic pyrrolidinyl substituent, the substituent being bonded to a quinolone mother skeleton Q containing a pyridobenzoxazine structure.

Abstract: There is provided a novel compound that inhibits phosphatidylinositol 3-kinase (PI3K) and/or the mammalian target of rapamycin (mTOR) and exhibits anti-tumor activity. The present invention provides a compound represented by the following formula (1) having various substituents that inhibits PI3K and/or mTOR and exhibits anti-tumor activity: wherein R1, R2, R3, R4, Ra, Rb, Rc, and X each have the same meaning as defined in the specification.

Abstract: A quinolone synthetic antibacterial agent having excellent properties as a medicine is provided, which has strong antibacterial activity not only to Gram-negative bacteria but also to Gram-positive cocci that have low sensitivity to quinolone antibacterial agents, and which exhibits high safety and excellent pharmacokinetics. A compound represented by the formula (I) or a salt thereof, or a hydrate thereof. Specifically, a quinolone derivative of the formula (I) wherein substituents R6 and R7 taken together with the carbon atoms to which they are bonded form a cyclic structure which may contain an oxygen atom as a ring constituent atom, the cyclic structure forming a 5-4, 5-5, or 5-6 fused bicyclic pyrrolidinyl substituent, the substituent being bonded to a quinolone mother skeleton Q containing a pyridobenzoxazine structure.

Abstract: There is provided a novel compound that inhibits phosphatidylinositol 3-kinase (PI3K) and/or the mammalian target of rapamycin (mTOR) and exhibits anti-tumor activity. The present invention provides a compound represented by the following formula (1) having various substituents that inhibits PI3K and/or mTOR and exhibits anti-tumor activity: wherein R1, R2, R3, R4, Ra, Rb, Rc, and X each have the same meaning as defined in the specification.

Abstract: There is provided a novel compound that inhibits phosphatidylinositol 3-kinase (PI3K) and/or the mammalian target of rapamycin (mTOR) and exhibits anti-tumor activity. The present invention provides a compound represented by the following formula (1) having various substituents that inhibits PI3K and/or mTOR and exhibits anti-tumor activity: wherein R1, R2, R3, R4, Ra, Rb, Rc, and X each have the same meaning as defined in the specification.

Abstract: There is provided a novel compound that inhibits phosphatidylinositol 3-kinase (PI3K) and/or the mammalian target of rapamycin (mTOR) and exhibits anti-tumor activity. The present invention provides a compound represented by the following formula (1) having various substituents that inhibits PI3K and/or mTOR and exhibits anti-tumor activity: wherein R1, R2, R3, R4, Ra, Rb, Rc, and X each have the same meaning as defined in the specification.

Abstract: A compound represented by the following formula (I): wherein R1 represents hydrogen, aryl which may have a substituent, a saturated or unsaturated 5- to 7-membered heterocyclic group which may have a substituent, etc.; R2 represents hydrogen, aryl which may have a substituent, a saturated or unsaturated 5- to 7-membered heterocyclic group which may have a substituent, etc.; R3 represents hydrogen, etc.; Ar represents a divalent group derived from aromatic hydrocarbon, etc.; X represents a single bond, linear or branched alkylene having from 1 to 3 carbon atoms which may have a substituent, etc.; and G represents halogen, a saturated or unsaturated 5- or 6-membered cyclic hydrocarbon group which may have a substituent, a saturated or unsaturated 5- to 7-membered heterocyclic group which may have a substituent, etc.

Abstract: An object of the present invention is to provide a method of double color-molding a key top, which is superior in design. In order to achieve this object, according to the method of double color-molding a key top provided in the present invention, at a first shot, an outer part that forms an outer line of a closed loop in a letter, figure, mark, etc., and an inner part that forms an inner line of the closed loop, are injection-molded with light-shielding resin using light-shielding resin. At a second shot, a light-permeable resin layer is injection-molded in such a manner that it covers a gate trace formed on both the outer part and the inner part. When light-permeable resin is used for the light-permeable resin layer, the gate trace is hardly invisible when the back light is off.

Abstract: An object of the present invention is to provide a method of double color-molding a key top that is superior in design. In order to achieve this object, according to the method of double color-molding a key top provided in the present invention, at a first shot, a light-permeable resin layer is injection-molded, and simultaneously, a convex portion that corresponds to a planar shape of a closed loop in a letter, figure, sign, etc., is formed on a back surface of the light-permeable layer. In a second shot, a light-shielding resin layer is injection-molded on both an outer region and an inner region which are defined by a convex pattern of the convex portion on the back surface of the light-permeable resin layer. Since a gate trace, which remains after performing the gate-cut on the light-shielding resin layer, resides inside the key top, it is invisible from the outside of the key top. In this way, the design of a key top can be improved.

Abstract: It is an object of the present invention to provide a communication device which is capable of being used for hands-free calls and which is easy to use. In order to achieve this object, the hands-free communication device of the present invention comprises an operating part including operation keys and a telephone receiver and microphone unit constructed in a manner freely attachable to and detachable from the operating part via an attachment. The telephone receiver and microphone unit comprises a microphone and a speaker, which are connected and integrated with each other via a connector. This configuration makes it possible to obtain the operability similar to that of a mobile cellular phone by mounting the telephone receiver and microphone unit on the operating part, and to realize the great convenience of being able to make hands-free calls by detaching the telephone receiver and microphone unit from the operating part.

Abstract: A motor 3 having a rotational shaft with a counterweight 4 is held in a vibrator holder 2. The rotational shaft of the motor is inserted at a free end in a circular hole in a bearing-plate of the vibrator holder 2. The vibrator holder 2 with the motor therein is accommodates in a vibrator accommodating section 120 formed in a housing 12 of a portable terminal and fixed with screws 5 to the housing 12. The vibrator holder 120 is then covered with an index cover 17 to thereby complete the vibrator attachment, which reduces a vibrator attaching work load. The inner wall of the vibrator accommodating section 120 faces the motor to thereby prevent the motor 3 from slipping from the holder.

Abstract: A relay lifter comprises a hook switch unit for turning ON/OFF a hook switch in response to a talk switch, a voice switching unit for switching connection of an aural signal in said corded telephone set between a transmitter/receiver of said corded telephone set and a cordless telephone set, and a bell sound detection signal transfer unit, a bell sound is outputted from said cordless telephone set when a bell sound is detected and an incoming call is accepted, a hook switch is turned ON/OFF using a hook switch ON/OFF unit, and connection of an aural signal in said corded telephone set is switched to said cordless telephone set for transmitting and receiving voice using said cordless telephone set.

Abstract: The is provided by the present invention a telephone system with high versatility comprising a corded telephone set, a cordless telephone set, and a relay lifter, wherein said relay lifter comprises a hook switch unit for turning ON/OFF a hook switch of the corded telephone set according to a first control signal responding to the talk switch, and a voice switching unit for switching connection of an aural signal in the corded telephone set according to a second control signal between a transmitter/receiver of the corded telephone set and the cordless telephone set, and switches connection of an aural signal in the corded telephone set to the cordless telephone set using the voice switching unit to transmit or receive voice using the cordless telephone set.