Patents by Inventor Takashi Osono

Takashi Osono has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 7-methoxy cephalosporin derivative
    Patent number: 4656262
    Abstract: The 7-methoxy-3-heterocyclic thiomethyl cephalosporin derivative possessing excellent antimicrobial activity represented by the general formula ##STR1## wherein R.sup.1 represents ##STR2## group or HOOC-- group, R.sup.2 represents a nitrogen-containing heterocyclic group, and M represents a hydrogen atom or a cation residue forming a salt.
    Type: Grant
    Filed: December 13, 1985
    Date of Patent: April 7, 1987
    Assignee: Yamanouchi Pharmaceutical Co., Ltd.
    Inventors: Takashi Osono, Yoshihiko Oka, Shunichi Watanabe, Takeshi Saito, Hiroshi Gushima, Keisuke Murakami, Isao Takahashi, Hiroshi Yamaguchi, Toshio Sasaki, Kiyoshi Susaki, Shuichi Takamura, Toshiaki Miyoshi
  • Process for the production of 7.alpha.-methoxycephalosporin derivatives
    Patent number: 4410626
    Abstract: 7.alpha.-Methoxy-3-p-sulfooxy or p-hydroxycinnamoyloxymethyl cephalosporin derivatives which are useful as antibiotics and as intermediates for the production of other 7.alpha.-methoxycephalosporin derivatives.
    Type: Grant
    Filed: October 29, 1980
    Date of Patent: October 18, 1983
    Assignee: Yamanouchi Pharmaceutical Co. Ltd.
    Inventors: Hiroshi Gushima, Shunichi Watanabe, Takeshi Saito, Toshio Sasaki, Hideo Eiki, Yoshihiko Oka, Takashi Osono
  • Process for production of aminoglycoside antibiotics
    Patent number: 4279997
    Abstract: Aminoglycoside antibiotics biochemically transformed from Kanamycin A or Kanamycin B, which are represented by the formula ##STR1## wherein R.sub.1 represents a hydrogen atom or a methyl group and R.sub.2 represents an amino group or a hydroxyl group.
    Type: Grant
    Filed: September 5, 1979
    Date of Patent: July 21, 1981
    Assignee: Yamanouchi Pharmaceutical Co., Ltd.
    Inventors: Yoshihiko Oka, Hitoshi Ishida, Moto Morioka, Yoso Numusaki, Tsutomu Yamafuji, Takashi Osono, Hamao Umezawa
  • 7.alpha.-Methoxycephalosporin derivatives
    Patent number: 4259326
    Abstract: 7.alpha.-Methoxy-3-p-sulfooxy or p-hydroxycinnamoyloxymethyl cephalosporin derivatives which are useful as antibiotics and as intermediates for the production of other 7.alpha.-methoxycephalosporin derivatives.
    Type: Grant
    Filed: November 27, 1979
    Date of Patent: March 31, 1981
    Assignee: Yamanouchi Pharmaceutical Co., Ltd.
    Inventors: Hiroshi Gushima, Shunichi Watanabe, Takeshi Saito, Toshio Sasaki, Hideo Eiki, Yoshihiko Oka, Takashi Osono
  • 7-Methoxy cephalosporins and process of producing them
    Patent number: 4242449
    Abstract: The 7-methoxy-3-heterocyclic thiomethyl cephalosporin derivative possessing excellent antimicrobial activity represented by the general formula ##STR1## wherein R.sup.1 represents ##STR2## group or HOOC-- group, R.sup.2 represents a nitrogen-containing heterocyclic group, and M represents a hydrogen atom or a cation residue forming a salt.
    Type: Grant
    Filed: February 21, 1978
    Date of Patent: December 30, 1980
    Assignee: Yamanouchi Pharmaceutical Co., Ltd.
    Inventors: Takashi Osono, Yoshihiko Oka, Shunichi Watanabe, Takeshi Saito, Hiroshi Gushima, Keisuke Murakami, Isao Takahashi, Hiroshi Yamaguchi, Toshio Sasaki, Kiyoshi Susaki, Shuichi Takamura, Toshiaki Miyoshi
  • Aminoglycoside antibiotics and process for production thereof
    Patent number: 4209511
    Abstract: Aminoglycoside antibiotics biochemically transformed from Kanamycin A or Kanamycin B, which are represented by the formula ##STR1## wherein R.sub.1 represents a hydrogen atom or a methyl group and R.sub.2 represents an amino group or a hydroxyl group.
    Type: Grant
    Filed: January 3, 1979
    Date of Patent: June 24, 1980
    Assignees: Yamanouchi Pharmaceutical Co., Ltd., Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai
    Inventors: Yoshihiko Oka, Hitoshi Ishida, Moto Morioka, Yoso Numasaki, Tsutomu Yamafuji, Takashi Osono, Hamao Umezawa
  • Antibiotic Y-G19Z D3 and the production thereof
    Patent number: 4039660
    Abstract: A new antibiotic substance, designated Y-G19ZD3, is produced by the fermentation of a newly discovered microorganism Streptomyces organonensis Y-G19Z or a mutant thereof. The antibiotic substance Y-G19ZD3 is effective against gram negative bacteria and is useful also as an intermediate for the production of other antibiotics.
    Type: Grant
    Filed: September 16, 1975
    Date of Patent: August 2, 1977
    Assignee: Yamanouchi Pharmaceutical Co., Ltd.
    Inventors: Takashi Osono, Shunichi Watanabe, Takeshi Saito, Hiroshi Gushima, Keisuke Murakami, Isao Takahashi, Hiroshi Yamaguchi, Toshio Sasaki, Yoshihiko Oka
  • Process for the production of monopropionyl-josamycin-2
    Patent number: 4001399
    Abstract: Alkanoyl-josamycins having no bitter taste, in which at least one of the two secondary hydroxyl groups of Josamycin is acylated (introduction of alkanoyl group).
    Type: Grant
    Filed: May 23, 1975
    Date of Patent: January 4, 1977
    Assignee: Yamanouchi Pharmaceutical Co., Ltd.
    Inventors: Takashi Osono, Kiruko Moriyama, Keisuke Murakami, Hamao Umezawa
  • Alkamoyl-josamycins
    Patent number: 3959252
    Abstract: Alkanoyl-josamycins having no bitter taste, in which at least one of the two secondary hydroxyl groups of Josamycin is acylated (introduction of alkanoyl group). The compounds have the same pharmaceutical effect as Josamycin which is effective in inhibiting the growth of Gram-positive bacteria.
    Type: Grant
    Filed: August 21, 1972
    Date of Patent: May 25, 1976
    Assignee: Yamanouchi Pharmaceutical Co., Ltd.
    Inventors: Takashi Osono, Kiruko Moriyama, Keisuke Murakami, Hamao Umezawa