Abstract: A bump inspection device images a wafer that includes a plurality of bumps arranged in parallel to each other. Each of the bumps is elongated along a first direction that is along a substrate surface. The bump inspection device includes: a laser-light source that emits laser light in a direction that is inclined relative to the substrate surface; a camera that images the substrate surface onto which the laser light is emitted; and a direction adjusting portion that adjusts an arrangement relation between the direction in which the laser light is emitted and an orientation of the wafer to allow the first direction to become inclined relative to the direction in which the laser light is emitted, in a plan view. The camera images the wafer while the first direction is inclined relative to the direction in which the laser light is emitted, in a plan view.

Abstract: Positive allosteric modulators (PAMs) of Mas-related G protein-coupled receptor X1 (MRGPRX1) and their use for treating neuropathic pain is disclosed.

Abstract: A connector includes a housing having a first connection portion and a second connection portion adjacent to the first connection portion, a first cap and a second cap pivotally supported by the housing respectively to be displaceable between an open position where the first and second connection portions are exposed to outside and a closed position where the first and second connection portions are shielded from the outside, a first lock and a second lock rotatably supported by the housing to lock the first cap and the second cap respectively, and a power transmission member rotatably supported by the housing. The power transmission member is configured to transmit a rotational force in a lock releasing direction of the second lock to the first lock such that the first cap and the second cap are integrally displaced to the open position.

Abstract: A connector includes a housing having a first connection portion and a second connection portion adjacent to the first connection portion, a first cap and a second cap pivotally supported by the housing respectively to be displaceable between an open position where the first and second connection portions are exposed to outside and a closed position where the first and second connection portions are shielded from the outside, a first lock and a second lock rotatably supported by the housing configured to lock the first cap and the second cap respectively. The second lock has a power transmission portion configured to transmit a rotational force in a lock releasing direction of the second lock to the first lock such that the first cap and the second cap are integrally displaced to the open position.

Abstract: A thin plate molding material includes a resin composition containing a resin component and a filling material, and a reinforced fiber with a predetermined fiber length. The content ratio of the reinforced fiber is a predetermined ratio. The mixing ratio of the resin component is a predetermined ratio.

Abstract: Currently available glutaminase inhibitors are generally poorly soluble, metabolically unstable, and/or require high doses, which together reduce their efficacy and therapeutic index. These can be formulated into nanoparticles and delivered safely and effectively for treatment of pancreatic cancer and other glutamine addicted cancers. Studies demonstrate that nanoparticle delivery of BPTES, relative to use of BPTES alone, can be safely administered and provides dramatically improved tumor drug exposure, resulting in greater efficacy. GLS inhibitors can be administered in higher concentrations with sub-100 nm nanoparticles, since the nanoparticles package the drug into “soluble” colloidal nanoparticles, and the nanoparticles deliver higher drug exposure selectively to the tumors due to the enhanced permeability and retention (EPR) effect. These factors result in sustained drug levels above the IC50 within the tumors for days, providing significantly enhanced efficacy compared to unencapsulated drug.

Abstract: Small molecule inhibitors of neutral sphingomyelinase 2 (nSMase2) and their use for treating neurodegenerative diseases, such as, neurodegenerative diseases associated with high levels of ceramide, including, but not limited to Alzheimer's disease (AD), HIV-associated neurocognitive disorder (HAND), multiple sclerosis (MS), and amyotrophic lateral sclerosis (ALS), and, in other aspects, for treating cancer or HIV-1, are provided.

Abstract: An unsaturated polyester resin composition includes an unsaturated polyester, a polymerizable monomer, a low shrinkage agent, aluminum hydroxide, and an electrically conductive filler. The unsaturated polyester is a polymerization product of a polybasic acid including a polybasic acid having an ethylenically unsaturated double bond at a predetermined ratio and a polyhydric alcohol. A polyvinyl acetate as the low shrinkage agent is included at a predetermined ratio with respect to the total amount of the unsaturated polyester, the polymerizable monomer, and the low shrinkage agent. The aluminum hydroxide is included at a predetermined ratio with respect to the total amount of the unsaturated polyester, the polymerizable monomer, and the low shrinkage agent.

Abstract: Provided is a display system, which makes it easy for an operator to accurately grasp a traveling situation of a work vehicle. A front camera captures an excavating blade and topography in front of a crawler dozer. A rear camera captures a fuel tank and a ripper apparatus, and a topography behind the crawler dozer. A display image displayed on a monitor is generated by arranging a front image captured by the front camera and a rear image captured by the rear camera so that the excavating blade in the front image may face the fuel tank in the rear image.

Abstract: An unsaturated polyester resin composition includes: a resin component comprising an unsaturated polyester, a polymerizable monomer, and a low profile agent; aluminum hydroxide; and a fire retardant. The unsaturated polyester is a polymerized product of polybasic acid and polyhydric alcohol. The polybasic acid has an ethylenic unsaturated double bond at a predetermined ratio. The polyvinyl acetate is blended as a low profile agent relative to the resin component at a predetermined ratio. Aluminum hydroxide is blended relative to the resin component at a predetermined ratio.

Abstract: Currently available glutaminase inhibitors are generally poorly soluble, metabolically unstable, and/or require high doses, which together reduce their efficacy and therapeutic index. These can be formulated into nanoparticles and delivered safely and effectively for treatment of pancreatic cancer and other glutamine addicted cancers. Studies demonstrate that nanoparticle delivery of BPTES, relative to use of BPTES alone, can be safely administered and provides dramatically improved tumor drug exposure, resulting in greater efficacy. GLS inhibitors can be administered in higher concentrations with sub-100 nm nanoparticles, since the nanoparticles package the drug into “soluble” colloidal nanoparticles, and the nanoparticles deliver higher drug exposure selectively to the tumors due to the enhanced permeability and retention (EPR) effect. These factors result in sustained drug levels above the IC50 within the tumors for days, providing significantly enhanced efficacy compared to unencapsulated drug.

Abstract: An amount of information of data of a captured image displayed on a display unit is increased. A display control unit sets a plurality of divided display sections for a display unit. The display control unit sets a first camera group and a second camera group including one or more of a plurality of cameras. The first camera group captures an image of a work performed with a blade. The second camera group captures an image of a work performed with a ripper. The display control unit displays data of captured images output from cameras included in one of the first and second camera groups in a corresponding plurality of divided display sections.

Abstract: A cab is used in a work machine. The cab includes a first pillar, a second pillar disposed to a rear of the first pillar, a beam disposed between the first pillar and the second pillar, and a reinforcing member provided to the beam.

Abstract: A display system includes a work vehicle, a first camera, a computation device, and a display device. The first camera is attached to one side portion of the work vehicle. The first camera has an optical axis inclined downward with respect to a horizontal direction. The first camera captures a first image including a surrounding environment of the work vehicle and a first vehicle body portion. The computation device generates a display image from the first image. The display image includes a surrounding image that depicts the surrounding environment of the work vehicle in a bird's-eye view, and a vehicle image. The vehicle image may combine a vehicle model depicted in the work vehicle and an image of the first vehicle body portion captured by the first camera, or may be an image of the first vehicle body portion. The display device displays the display image.

Abstract: A bulldozer includes a blade disposed in front of a vehicle body. First and second cameras are disposed to the left and right of the vehicle body, respectively. A first optical axis of the first camera faces forward and downward. The first camera is arranged to capture a first image of a gap between a lower edge of the blade and the left crawler belt. A second optical axis of the second camera faces forward and downward. The second camera is arranged to capture a second image of a gap between a lower edge of the blade and the right crawler belt. A display is configured to display the first and second images side-by-side.

Abstract: A cab is used in a work machine. The cab includes a first pillar, a second pillar disposed to a rear of the first pillar, a beam disposed between the first pillar and the second pillar, and a reinforcing member provided to the beam.

Abstract: A bulldozer includes a blade disposed in front of a vehicle body. First and second cameras are disposed to the left and right of the vehicle body, respectively. A first optical axis of the first camera faces forward and downward. The first camera is arranged to capture a first image of a gap between a lower edge of the blade and the left crawler belt. A second optical axis of the second camera faces forward and downward. The second camera is arranged to capture a second image of a gap between a lower edge of the blade and the right crawler belt. A display is configured to display the first and second images side-by-side.

Abstract: Provided is a display system capable of facilitating appropriate ripping work. A right ripper side camera images a ripping tip. The right ripper side camera is mounted on a vehicle main body. The image generating unit generates a display image. The display image includes an image of the ripping tip by an imaging unit and information about a rotative running of a crawler belt. A display unit displays the display image.

Abstract: A bulldozer includes a blade disposed in front of a vehicle body. First and second cameras are disposed to the left and right of the vehicle body, respectively. A first optical axis of the first camera faces forward and downward. The first camera overlaps a left crawler belt as seen in a plan view of the bulldozer and is arranged to capture a first image of a gap between a lower edge of the blade and the left crawler belt. A second optical axis of the second camera faces forward and downward. The second camera overlaps a right crawler belt as seen in a plan view of the bulldozer and is arranged to capture a second image of a gap between a lower edge of the blade and the right crawler belt. A display is configured to display the first and second images side-by-side.

Abstract: A connector includes a housing that has a terminal accommodating chambers into which terminals are inserted and a housing flexible piece for locking and preventing the terminals from coming off, a rear holder that includes terminal insertion openings and is mounted on the housing at a temporary locking position and a final locking position, the retainer part is disposed at a position just before the retainer is engaged with the housing flexible piece when the rear holder is at the temporary locking position, and the retainer part is disposed at a position where the retainer part restrains the locking release of the housing flexible piece when the rear holder is at the final locking position, and a rail part that is formed in the housing and restrains a movement of the retainer in an inclination direction of a mounting direction by slide contact to the retainer part.