Patents by Inventor Takashi Yamano

Takashi Yamano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CRYSTAL STRUCTURE OF CRISPR CPF1
    Publication number: 20240035006
    Abstract: The invention provides for systems, methods, and compositions for targeting nucleic acids. In particular, the invention provides non-naturally occurring or engineered DNA or RNA-targeting systems comprising a novel DNA or RNA-targeting CRISPR effector protein and at least one targeting nucleic acid component like a guide RNA.
    Type: Application
    Filed: November 14, 2022
    Publication date: February 1, 2024
    Applicants: The Broad Institute, Inc., Massachusetts Institute of Technology, University of Tokyo, The United States of America, as Represented by the Secretary Dept of Health and Human Services
    Inventors: Takashi Yamano, Hiroshi Nishimasu, Bernd Zetsche, Ian Slaymaker, Yinqing Li, Iana Fedorova, Kira Makarova, Linyi Gao, Eugene Koonin, Feng Zhang, Osamu Nureki
  • CRYSTAL STRUCTURE OF CRISPR CPF1
    Publication number: 20190264186
    Abstract: The invention provides for systems, methods, and compositions for targeting nucleic acids. In particular, the invention provides non-naturally occurring or engineered DNA or RNA-targeting systems comprising a novel DNA or RNA-targeting CRISPR effector protein and at least one targeting nucleic acid component like a guide RNA.
    Type: Application
    Filed: January 23, 2017
    Publication date: August 29, 2019
    Applicants: The Broad Institute Inc., Massachusetts Institute of Technology, University of Tokyo, The USA, As Represented by The Secretary Department of Health and Human Services
    Inventors: Takashi Yamano, Hiroshi Nishimasu, Bernd Zetsche, Ian Slaymaker, Yinqing Li, Iana Fedorova, Kira Makarova, Linyi Gao, Eugene Koonin, Feng Zhang, Osamu Nureki
  • Method of transferring gene into algal cell involving utilizing multiple square-wave pulses in three steps
    Patent number: 9255276
    Abstract: A method of transferring an exogenous gene into a eukaryotic algal cell, the method including performing electroporation using multiple square-wave pulses to the solution containing a cell of a green alga with cell-wall, and a nucleic acid molecule by the following three steps: applying a square-wave electric pulse (first electric pulse) with a high voltage for a short period of time under the condition that its total electric energy falls within a predetermined range; then applying a square-wave electric pulse (second electric pulse) with a low voltage for a long period of time two or more times; and then applying a square-wave electric pulse (third electric pulse) that is opposite in polarity to the second electric pulse, with a low voltage for a long period of time, two or more times.
    Type: Grant
    Filed: February 10, 2014
    Date of Patent: February 9, 2016
    Assignees: Kyoto University, Nepa Gene Co., Ltd.
    Inventors: Hideya Fukuzawa, Takashi Yamano, Kentaro Ifuku, Yasuhiko Hayakawa
  • METHOD OF TRANSFERRING GENE INTO ALGAL CELL INVOLVING UTILIZING MULTIPLE SQUARE-WAVE PULSES IN THREE STEPS
    Publication number: 20150011008
    Abstract: To provide a technology that solves the above-mentioned problems, and is directly applicable to eukaryotic algal cells with cell-wall, the technology enabling gene transfer and transformation to be performed with high efficiency and good reproducibility irrespective of species of algae.
    Type: Application
    Filed: February 10, 2014
    Publication date: January 8, 2015
    Applicants: Nepa Gene Co., Ltd., Kyoto University
    Inventors: Hideya FUKUZAWA, Takashi Yamano, Kentaro Ifuku, Yasuhiko Hayakawa
  • Hard disk driving device having a plurality of head sliders with equalized flotation height
    Patent number: 5053904
    Abstract: A hard disk driving device in which a plurality of hard disks each formed with a magnetic recording layer are secured to the same rotational shaft in a predetermined spaced relation, and a magnetic head mounted on a floating (flying) type head slider is disposed on each surface, characterized in that an area of a portion concerned with flotation of a head slider provided on a head slider assembly sandwiched between adjacent hard disks is made to be smaller than an area of a portion concerned with flotation of a head slider provided on a head slider assembly sandwiched between adjacent hard disks.
    Type: Grant
    Filed: April 3, 1990
    Date of Patent: October 1, 1991
    Assignee: Alps Electric Co., Ltd.
    Inventors: Takashi Yamano, Yasushi Katanuma, Hideyasu Takemura, Michiko Kumagai, Hiroshi Yoshida, Toru Kaneko