Abstract: A polarizing plate with optical compensation function, including a polarizing layer and an optically compensating layer, wherein the optically compensating layer includes an optically compensating A-layer including a stretched polymer film and an optically compensating B-layer including a cholesteric liquid crystal layer.

Abstract: The present invention relates to provide a non-human animal model unresponsive to a synthetic compound wherein a gene function encoding TLR7 that recognizes an immunopotentiating synthetic compound such as imidazoquinoline lacks on is genomic locus. Whole or part of a gene fragment of a gene site including an intracellular region and a transmembrane region of a TLR7 gene obtained from a mouse gene library is replaced by a plasmid including poly A signal and a marker gene to construct a targeting vector. Then, this targeting vector is linearized and transferred into embryonic stem cells. The target embryonic stem cells wherein the TLR7 gene function is deleted are microinjected into a mouse blastocyst to generate a chimeric mouse. Then, this chimeric mouse is crossed with a wild-type mouse to generate a heterozygote mouse. Next, the heterozygote mice are intercrossed to obtain a TLR7 knockout mouse.

Abstract: An optical compensating film using a norbornene-based resin film in which the durability at an interface surface of the adhesive of a LCD is improved, a polarizing plate, and a liquid crystal display using the same is provided. The optical compensating film of the present invention is formed by coating an adhesive on a stretched norbornene-based resin film. In the optical compensating film, the adhesive force between the optical compensating film and the adhesive layer is 10 N/20 mm or more.

Abstract: The present invention provides an optical compensation plate having an optical compensation layer in which occurrence of cracks due to an applied pressure and deformation caused by heat or the like are suppressed. By applying an adhesive that contains a moisture-curing isocyanate compound and has a glass transition temperature of 100° C. or less onto at least one surface of the optical compensation layer and curing the adhesive, an anti-cracking layer is formed directly on the surface of the optical compensation layer. The occurrence of cracks and the deformation in the optical compensation layer can be prevented by this anti-cracking layer. The optical compensation layer preferably is a layer having a cholesteric structure, and a constituent material thereof preferably is a non-liquid crystal polymer formed by polymerizing aligned liquid crystal monomers or an aligned liquid crystal polymer.

Abstract: An inclined optical compensation film formed from a non-liquid-crystal polymer, which is useful in a TN mode liquid crystal display. A substrate is coated with a non-liquid-crystal polymer to thereby form a coating film; the non-liquid-crystal polymer of the coating film is inclined and aligned; and the coating film is solidified, thereby forming an inclined optical compensation film. The non-liquid-crystal polymer can be inclined and aligned by, for example, applying external force, such as wind blowing, to the coating film. This inclined optical compensation film exhibits, for example, a birefringence (?n) ranging from 0.001 to 0.5 and thus is useful in a TN mode liquid crystal display, etc.

Abstract: A method for preparing an optical film, which comprises applying and developing an application liquid mixture containing a liquid crystal monomer, a chiral agent and a polymerization initiator on an orientation substrate, subjecting the resultant developed layer to a heat treatment, to orient the monomer to a cholesteric structure, and then subjecting the developed layer to a poltmerization treatment, to polymerize the oriented liquid crystal monomer, thereby forming an optical film exhibiting a selective reflection wave length of 100 to 320 nm. An optical film prepared by the above method is reduced in the coloring due to selective reflection.

Abstract: A retardation plate with protective films of the present invention comprises a retardation plate; and at least two protective films that each comprise a base film and a pressure-sensitive adhesive layer formed on one side of the base film and are sequentially laminated on the retardation plate, wherein the first protective film laminated on the retardation plate differs in adhesive strength to adherend from the protective film or films other than the first protective film, and the first protective film has the lowest adhesive strength. The retardation plate with protective films can suppress curling and has good workability and good peelability even when using a thin retardation plate.

Abstract: The present invention provides an optical compensation plate having an optical compensation layer in which cracks occurring due to an applied pressure is suppressed. By applying a curable adhesive agent onto at least one surface of the optical compensation layer and curing the adhesive, an anti-cracking layer is formed directly on the surface of the optical compensation layer. The occurrence of cracks in the optical compensation layer can be prevented by this anti-cracking layer. The optical compensation layer preferably is a layer having a cholesteric structure, and the constituent material thereof is preferably a non-liquid crystal polymer formed by polymerizing aligned liquid crystal monomers or an aligned liquid crystal polymer.

Abstract: The present invention provides a coating material for forming a coating layer that can achieve excellent adhesion to a transparent film. The coating material is prepared so that it contains a thermosetting resin, an inorganic filler, and a mixed solvent containing cyclohexanone. The content of the thermosetting resin is in the range from 5 to 20 wt % with respect to the total amount of the thermosetting resin and the inorganic filler, and the content of the cyclohexanone is in the range from 25 to 35 wt % with respect to the entire mixed solvent. By coating a surface of a transparent film with this coating material and then heat-treating the resultant coating, a coating layer with excellent adhesion can be formed on transparent film. The thus-obtained laminate of the transparent film and the coating layer can be used as an antireflection film.

Abstract: A polarizing plate with an optical compensation layer is provided, which has an excellent peelability and is easy to reattach after mounted on an image display apparatus. A pressure-sensitive adhesive layer satisfying the condition (I) below is formed on both surfaces of an optical compensation layer, and one of the pressure-sensitive adhesive layers is further laminated with a polarizing plate.

Abstract: The present invention provides a transparent optical film that has excellent optical characteristics for realizing the uniform retardation distribution and restraining rainbow-colored irregularities. The optical film, which is obtained by laminating a birefringent layer (a) on a transparent film (b), satisfies all the following formulae (I), (II) and (III). ?n(a)>?n(b)×10??(I) 1<(nx?nz)/(nx?ny)??(II) 0.0005??n(a)?0.5??(III) In the above formulae (I), (II) and (III), ?n(a) and ?n(b) denote respectively birefringent indexes of the birefringent layer (a) and the transparent film (b). The signs of nx, ny and nz indicate refractive indexes in an X-axis direction, a Y-axis direction and a Z-axis direction in the birefringent layer (a), respectively.

Abstract: A laminated quarter-wave plate having: a laminate of a quarter-wave plate and a half-wave plate, wherein: the quarter-wave plate and the half-wave plate are laminated on each other so that directions of in-plane slow axes intersect each other; and each of the quarter-wave plate and the half-wave plate satisfies a relation Nz=(nx?nz)/(nx?ny)>1.05 in which nx and ny are in-plane main refractive indices, and nz is a thicknesswise refractive index; and a circularly polarizing plate having: a laminate of a laminated quarter-wave plate defined above and a polarizer.

Abstract: The present invention provides an optical compensation plate having an optical compensation layer in which occurrence of cracks due to an applied pressure and deformation caused by heat or the like are suppressed. By applying an adhesive that contains a moisture-curing isocyanate compound and has a glass transition temperature of 100° C. or less onto at least one surface of the optical compensation layer and curing the adhesive, an anti-cracking layer is formed directly on the surface of the optical compensation layer. The occurrence of cracks and the deformation in the optical compensation layer can be prevented by this anti-cracking layer. The optical compensation layer preferably is a layer having a cholesteric structure, and a constituent material thereof preferably is a non-liquid crystal polymer formed by polymerizing aligned liquid crystal monomers or an aligned liquid crystal polymer.

Abstract: The present invention relates to provide a non-human animal model unresponsive to a synthetic compound wherein a gene function encoding TLR7 that recognizes an immunopotentiating synthetic compound such as imidazoquinoline lacks on is genomic locus. Whole or part of a gene fragment of a gene site including an intracellular region and a transmembrane region of a TLR7 gene obtained from a mouse gene library is replaced by a plasmid including poly A signal and a marker gene to construct a targeting vector. Then, this targeting vector is linearized and transferred into embryonic stem cells. The target embryonic stem cells wherein the TLR7 gene function is deleted are microinjected into a mouse blastocyst to generate a chimeric mouse. Then, this chimeric mouse is crossed with a wild-type mouse to generate a heterozygote mouse. Next, the heterozygote mice are intercrossed to obtain a TLR7 knockout mouse.

Abstract: The present invention provides an optical compensation plate having an optical compensation layer in which cracks occurring due to an applied pressure is suppressed. By applying a curable adhesive agent onto at least one surface of the optical compensation layer and curing the adhesive, an anti-cracking layer is formed directly on the surface of the optical compensation layer. The occurrence of cracks in the optical compensation layer can be prevented by this anti-cracking layer. The optical compensation layer preferably is a layer having a cholesteric structure, and the constituent material thereof is preferably a non-liquid crystal polymer formed by polymerizing aligned liquid crystal monomers or an aligned liquid crystal polymer.

Abstract: A polarizing plate with an optical compensation layer is provided, which has an excellent peelability and is easy to reattach after mounted on an image display apparatus. A pressure-sensitive adhesive layer satisfying the condition (I) below is formed on both surfaces of an optical compensation layer, and one of the pressure-sensitive adhesive layers is further laminated with a polarizing plate.

Abstract: An inclined optical compensation film formed from a non-liquid-crystal polymer, which is useful in a TN mode liquid crystal display. A substrate is coated with a non-liquid-crystal polymer to thereby form a coating film; the non-liquid-crystal polymer of the coating film is inclined and aligned; and the coating film is solidified, thereby forming an inclined optical compensation film. The non-liquid-crystal polymer can be inclined and aligned by, for example, applying external force, such as wind blowing, to the coating film. This inclined optical compensation film exhibits, for example, a birefringence (?n) ranging from 0.001 to 0.5 and thus is useful in a TN mode liquid crystal display, etc.

Abstract: The present invention provides a laminated retardation plate that shows an excellent viewing angle property when used in a liquid crystal display, and that can be decreased in thickness. The laminated retardation plate is formed by laminating an optically anisotropic layer (A) made of a polymer having an in-plane retardation of 20-300 nm and a ratio between a thickness direction retardation and the in-plane retardation of not less than 1.0, and an optically anisotropic layer (B) made of a non-liquid crystalline polymer such as polyimide having an in-plane retardation of not less than 3 nm and a ratio between a thickness direction retardation and the in-plane retardation of not less than 1.0. The thus obtained laminated retardation plate shows excellent optical properties, e.g., an in-plane retardation (Re) of 10 nm or more, and a difference between a thickness direction retardation and the in-plane retardation of 50 nm or more.

Abstract: A polarizing plate with optical compensation function, including a polarizing layer and an optically compensating layer, wherein the optically compensating layer includes an optically compensating A-layer including a stretched polymer film and an optically compensating B-layer including a cholesteric liquid crystal layer.

Abstract: A method for preparing an optical film, which comprises applying and developing an application liquid mixture containing a liquid crystal monomer, a chiral agent and a polymerization initiator on an orientation substrate, subjecting the resultant developed layer to a heat treatment, to orient the monomer to a cholesteric structure, and then subjecting the developed layer to a poltmerization treatment, to polymerize the oriented liquid crystal monomer, thereby forming an optical film exhibiting a selective reflection wave length of 100 to 320 nm. An optical film prepared by the above method is reduced in the coloring due to selective reflection.