Abstract: An antibody-drug conjugate represented by formula (I): (where Ab is an antibody, X is a group represented by formula (X-1), formula (X-2) or formula (X-3): (where at the left represents the binding site with NH and at the right represents the binding side with D), D is a group represented by formula (D-1) or formula (D-2): (where represents the binding site with X), and n is in the range of about 1 to about 8).

Abstract: A post-processing device (200) includes a circulation conveyance path, a zeroth conveyer (R0), and a controller (50). The circulation conveyance path includes a first conveyance path (W1), a second conveyance path (W2), a third conveyance path (W3), a first conveyer (R1), a second conveyer (R2), and a third conveyer (R3). The first and second conveyers convey a preceding sheet (P1) along the first and second conveyance paths. The third conveyer conveys it from the third conveyance path to the first conveyance path. The zeroth conveyer conveys a following sheet (P2) toward the first conveyer. The controller controls the third conveyer to stop the preceding sheet, subsequently controls the zeroth conveyer and the third conveyer to overlay the preceding sheet with the following sheet to form a sheet bundle (Q) having a shift amount (G) between a leading edges of the preceding sheet and the following sheet and strike the leading edges of the preceding sheet and the following sheet against the first conveyer.

Abstract: A post-processing apparatus includes a first conveyor, a second conveyor, a third conveyor, and a conveyance passage corrector. The first conveyor conveys a sheet conveyed along a first conveyance passage downstream from the first conveyor. The second conveyor conveys the sheet along a second conveyance passage. The third conveyor conveys the sheet along a third conveyance passage. The conveyance passage corrector includes a retracting mechanism to retract from a joining position at which the third conveyance passage joins to the first conveyance passage and turns a conveyance direction of the sheet toward the first conveyor when the sheet enters from the third conveyance passage to the first conveyance passage.

Abstract: A sheet processing device includes a first conveyance passage, a first conveyor, a second conveyor, a folder, a second conveyance passage, and circuitry. The circuitry is configured to (1) cause the first conveyor and the second conveyor to convey the sheet nipping the sheet to warp the sheet between the first conveyor and the second conveyor, (2) guide the warped sheet to form a first fold on the sheet by the folder and circulate the sheet to the first conveyance passage, (3) cause the first conveyor and the second conveyor to convey the sheet while nipping the sheet again to warp the sheet between the first conveyor and the second conveyor, (4) guide the warped sheet to form a second fold on the sheet by the folder, and (5) cause the second conveyor to convey the sheet with the first fold and the second fold.

Abstract: A sheet processing device includes a first conveyance passage, a first conveyor, a second conveyor, a folder, a second conveyance passage, and circuitry. The circuitry is configured to (1) cause the first conveyor and the second conveyor to convey the sheet nipping the sheet to warp the sheet between the first conveyor and the second conveyor, (2) guide the warped sheet to form a first fold on the sheet by the folder and circulate the sheet to the first conveyance passage, (3) cause the first conveyor and the second conveyor to convey the sheet while nipping the sheet again to warp the sheet between the first conveyor and the second conveyor, (4) guide the warped sheet to form a second fold on the sheet by the folder, and (5) cause the second conveyor to convey the sheet with the first fold and the second fold.