Patents by Inventor Takatoshi Hiroko

Takatoshi Hiroko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Apoptosis-inducing gene and utilization of the same
    Patent number: 7422906
    Abstract: The object of the present invention is to provide a protein useful for searching an apoptosis-inhibiting substance or an apoptosis-promoting substance, a gene encoding the above protein, a vector comprising the above gene, and a transformant comprising the above vector. The present invention provides an apoptosis-inducing protein of any one of the following (a), (b), and (c): (a) a protein having the amino acid sequence shown in SEQ ID NO: 2 of the sequence listing; (b) a protein, which has an amino acid sequence comprising a deletion, substitution, and/or addition of one or several amino acids with respect to the amino acid sequence shown in SEQ ID NO: 2 of the sequence listing, and has activity of inducing apoptosis; and (c) a protein, which has an amino acid sequence showing homology of 95% or more with the amino acid sequence shown in SEQ ID NO: 2 of the sequence listing, and has activity of inducing apoptosis.
    Type: Grant
    Filed: February 10, 2004
    Date of Patent: September 9, 2008
    Assignees: Taisho Pharmaceutical Co., Ltd.
    Inventors: Tetsu Akiyama, Takatoshi Hiroko
  • Apoptosis-inducing gene and utilization of the same
    Publication number: 20060172930
    Abstract: The object of the present invention is to provide a protein useful for searching an apoptosis-inhibiting substance or an apoptosis-promoting substance, a gene encoding the above protein, a vector comprising the above gene, and a transformant comprising the above vector. The present invention provides an apoptosis-inducing protein of any one of the following (a), (b), and (c): (a) a protein having the amino acid sequence shown in SEQ ID NO: 2 of the sequence listing; (b) a protein, which has an amino acid sequence comprising a deletion, substitution, and/or addition of one or several amino acids with respect to the amino acid sequence shown in SEQ ID NO: 2 of the sequence listing, and has activity of inducing apoptosis; and (c) a protein, which has an amino acid sequence showing homology of 95% or more with the amino acid sequence shown in SEQ ID NO: 2 of the sequence listing, and has activity of inducing apoptosis.
    Type: Application
    Filed: February 10, 2004
    Publication date: August 3, 2006
    Inventors: Tetsu Akiyama, Takatoshi Hiroko