Patents by Inventor Takatsuka Yashiki

Takatsuka Yashiki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for producing microcapsule
    Patent number: 5631020
    Abstract: A microcapsule produced by preparing a water-in-oil emulsion comprising an inner aqueous layer containing said water-soluble drug and a drug retaining substance therefor and an oil layer containing a polymer substance, then thickening or solidifying said inner aqueous layer to a viscosity of not lower than about 5000 centiposes and finally subjecting the resulting emulsion to in water drying gives prolonged release of water-soluble drug.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: May 20, 1997
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Hiroaki Okada, Yasuaki Ogawa, Takatsuka Yashiki
  • Method for producing microcapsule
    Patent number: 5631021
    Abstract: A microcapsule produced by preparing a water-in-oil emulsion comprising an inner aqueous layer containing said water-soluble drug and a drug retaining substance therefor and an oil layer containing a polymer substance, then thickening or solidifying said inner aqueous layer to a viscosity of not lower than about 5000 centiposes and finally subjecting the resulting emulsion to in water drying gives prolonged release of water-soluble drug.
    Type: Grant
    Filed: February 20, 1996
    Date of Patent: May 20, 1997
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Hiroaki Okada, Yasuaki Ogawa, Takatsuka Yashiki
  • Prolonged release microcapsule
    Patent number: 5476663
    Abstract: A microcapsule produced by preparing a water-in-oil emulsion comprising an inner aqueous layer containing said water-soluble drug and a drug retaining substance therefor and an oil layer containing a polymer substance, then thickening or solidifying said inner aqueous layer to a viscosity of not lower than about 5000 centiposes and finally subjecting the resulting emulsion to in water drying gives prolonged release of water-soluble drug.
    Type: Grant
    Filed: April 15, 1994
    Date of Patent: December 19, 1995
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Hiroaki Okada, Yasuaki Ogawa, Takatsuka Yashiki
  • Prolonged release microcapsule of a water-soluble drug
    Patent number: 5061492
    Abstract: A microcapsule produced by preparing a water-in-oil emulsion comprising an inner aqueous layer containing said water-soluble drug and a drug retaining substance therefor and an oil layer containing a polymer substance, then thickening or solidifying said inner aqueous layer to a viscosity of not lower than about 5000 centiposes and finally subjecting the resulting emulsion to in water drying gives prolonged release of water-soluble drug.
    Type: Grant
    Filed: January 24, 1990
    Date of Patent: October 29, 1991
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Hiroaki Okada, Yasuaki Ogawa, Takatsuka Yashiki
  • Prolonged release microcapsules
    Patent number: 4917893
    Abstract: A microcapsule produced by preparing a water-in-oil emulsion comprising an inner aqueous layer containing said water-soluble drug and a drug retaining substance therefor and an oil layer containing a polymer substance, then thickening or solidifying said inner aqueous layer to a viscosity of not lower than about 5000 centiposes and finally subjecting the resulting emulsion to in water drying gives prolonged release of water-soluble drug.
    Type: Grant
    Filed: September 30, 1987
    Date of Patent: April 17, 1990
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Hiroaki Okada, Yasuaki Ogawa, Takatsuka Yashiki
  • Prolonged release microcapsules and their production
    Patent number: 4711782
    Abstract: A microcapsule produced by preparing a water-in-oil emulsion comprising an inner aqueous layer containing said water-soluble drug and a drug retaining substance therefor and an oil layer containing a polymer substance, then thickening or solidifying said inner aqueous layer to a viscosity of not lower than about 5000 centiposes and finally subjecting the resulting emulsion to in water drying gives prolonged release of water-soluble drug.
    Type: Grant
    Filed: December 11, 1986
    Date of Patent: December 8, 1987
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Hiroaki Okada, Yasuaki Ogawa, Takatsuka Yashiki
  • Pharmaceutical composition and its rectal use
    Patent number: 4670419
    Abstract: A pharmaceutical composition containing a hydrophilic drug which is poorly absorbable through the gastrointestinal tract, and cyclodextrin, increases the absorbability of the drug into the mammalian body when administered by a non-oral or non-injection route.
    Type: Grant
    Filed: July 8, 1985
    Date of Patent: June 2, 1987
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Yoshiaki Uda, Shin-ichiro Hirai, Takatsuka Yashiki
  • Pharmaceutical composition and its nasal or vaginal use
    Patent number: 4659696
    Abstract: A pharmaceutical composition containing a hydrophilic drug which is poorly absorbable through the gastrointestinal tract, and cyclodextrin, increases the absorbability of the drug into the mammalian body when administered by a non-oral or non-injection route.
    Type: Grant
    Filed: April 22, 1983
    Date of Patent: April 21, 1987
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Shin-ichiro Hirai, Hiroaki Okada, Takatsuka Yashiki
  • Prolonged release microcapsule and its production
    Patent number: 4652441
    Abstract: A microcapsule produced by preparing a water-in-oil emulsion comprising an inner aqueous layer containing said water-soluble drug and a drug retaining substance therefor and an oil layer containing a polymer substance, then thickening or solidifying said inner aqueous layer to a viscosity of not lower than about 5000 centiposes and finally subjecting the resulting emulsion to in water drying gives prolonged release of water-soluble drug.
    Type: Grant
    Filed: November 1, 1984
    Date of Patent: March 24, 1987
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Hiroaki Okada, Yasuaki Ogawa, Takatsuka Yashiki
  • Double ester of 16.beta.-ethylestran-17.beta.-ol derivatives
    Patent number: 4609650
    Abstract: A novel steroid compound of the formula ##STR1## wherein A is a lower alkylene group; ##STR2## is an acyl group; and is a single bond or a double bond, and methods of producing the compound (I) as follows: ##STR3## and a pharmaceutical composition containing the compound (I). The compound (I) exhibits excellent antiandrogenic activity on oral administration and can be used for the treatment of prostatic hypertrophy.
    Type: Grant
    Filed: March 27, 1984
    Date of Patent: September 2, 1986
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Yoshinobu Yoshimura, Yoko Nishida, Takatsuka Yashiki
  • Pharmaceutical preparations containing TRH or its analogue
    Patent number: 4504470
    Abstract: A non-parenteral pharmaceutical preparation containing TRH, its salt, or its analogue is produced by employing the drug and a hydroxycarboxylic acid or polycarboxylic acid of 2 to 8 carbon atoms, and having the pH of the preparation adjusted to 2 to 6.
    Type: Grant
    Filed: May 12, 1982
    Date of Patent: March 12, 1985
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Yoshiaki Uda, Takatsuka Yashiki
  • Cephalosporin derivatives
    Patent number: 4497809
    Abstract: Cephalosporin derivatives of the formula: ##STR1## wherein R.sub.1 is methyl or ethyl and R.sub.2 is a straight-chain or branched alkyl group of 5 to 7 carbon atoms, and their pharmaceutically acceptable salts, which are effective as orally administrable antibiotic agents against both gram-positive- and negative-bacteria, and the production and compositions thereof, are proposed.
    Type: Grant
    Filed: April 20, 1983
    Date of Patent: February 5, 1985
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Yoshinobu Yoshimura, Naoru Hamaguchi, Takatsuka Yashiki
  • Preparations for vaginal administration
    Patent number: 4211769
    Abstract: A preparation containing, as the main pharmaceutically active ingredient, a peptide having a luteinizing hormone-releasing hormone activity, is improved in its absorption by adding thereto a water-soluble aliphatic carboxylic acid of 2 to 6 carbon atoms.
    Type: Grant
    Filed: August 17, 1978
    Date of Patent: July 8, 1980
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Hiroaki Okada, Iwao Yamazaki, Takatsuka Yashiki