Patents by Inventor Takayoshi SHIMOHATA

Takayoshi SHIMOHATA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cell preparation and method for producing cell preparation
    Patent number: 11311579
    Abstract: The present invention provides a method for producing a cell culture for promoting angiogenesis or axon outgrowth, particularly for the treatment of a cerebrovascular disease, an ischemic cardiac disease or traumatic brain injury and spinal cord injury, which comprises culturing a cell population containing microglia and/or monocytes under conditions of low oxygen concentration and/or low sugar concentration to produce the culture, a cell preparation obtained by the method, and a method for treating a cerebrovascular disease, an ischemic cardiac disease or traumatic cerebrospinal neuropathy by using the cell preparation.
    Type: Grant
    Filed: August 30, 2017
    Date of Patent: April 26, 2022
    Assignee: NIIGATA UNIVERSITY
    Inventors: Takayoshi Shimohata, Masato Kanazawa
  • CELL PREPARATION AND METHOD FOR PRODUCING CELL PREPARATION
    Publication number: 20190216856
    Abstract: The present invention provides a method for producing a cell culture for promoting angiogenesis or axon outgrowth, particularly for the treatment of a cerebrovascular disease, an ischemic cardiac disease or traumatic brain injury and spinal cord injury, which comprises culturing a cell population containing microglia and/or monocytes under conditions of low oxygen concentration and/or low sugar concentration to produce the culture, a cell preparation obtained by the method, and a method for treating a cerebrovascular disease, an ischemic cardiac disease or traumatic cerebrospinal neuropathy by using the cell preparation.
    Type: Application
    Filed: August 30, 2017
    Publication date: July 18, 2019
    Applicant: NIIGATA UNIVERSITY
    Inventors: Takayoshi SHIMOHATA, Masato KANAZAWA
  • Pharmaceutical composition for treating ischemic events
    Patent number: 9439961
    Abstract: Methods and pharmaceutical compositions for treating severe ischemic events including cerebral infarction, cardiac infarction, or pulmonary embolism, comprising a thrombolytic intervention including thrombolytic agents and an inhibitor of vascular endothelial growth factor (VEGF) receptor-mediated signal transduction are disclosed.
    Type: Grant
    Filed: January 9, 2014
    Date of Patent: September 13, 2016
    Assignee: NIIGATA UNIVERSITY
    Inventors: Takayoshi Shimohata, Lawrence M. Kauvar
  • PHARMACEUTICAL COMPOSITION FOR TREATING ISCHEMIC EVENTS
    Publication number: 20140127233
    Abstract: Methods and pharmaceutical compositions for treating severe ischemic events including cerebral infarction, cardiac infarction, or pulmonary embolism, comprising a thrombolytic intervention including thrombolytic agents and an inhibitor of vascular endothelial growth factor (VEGF) receptor-mediated signal transduction are disclosed.
    Type: Application
    Filed: January 9, 2014
    Publication date: May 8, 2014
    Applicant: NIIGATA UNIVERSITY
    Inventors: Takayoshi SHIMOHATA, Lawrence M. KAUVAR
  • Pharmaceutical composition for treating ischemic events
    Patent number: 8652476
    Abstract: Methods and pharmaceutical compositions for treating severe ischemic events including cerebral infarction, cardiac infarction, or pulmonary embolism, comprising a thrombolytic intervention including thrombolytic agents and an inhibitor of vascular endothelial growth factor (VEGF) receptor-mediated signal transduction are disclosed.
    Type: Grant
    Filed: January 26, 2012
    Date of Patent: February 18, 2014
    Assignee: Niigata University
    Inventors: Takayoshi Shimohata, Lawrence M. Kauvar
  • PHARMACEUTICAL COMPOSITION FOR TREATING ISCHEMIC EVENTS
    Publication number: 20120189631
    Abstract: Methods and pharmaceutical compositions for treating severe ischemic events including cerebral infarction, cardiac infarction, or pulmonary embolism, comprising a thrombolytic intervention including thrombolytic agents and an inhibitor of vascular endothelial growth factor (VEGF) receptor-mediated signal transduction are disclosed.
    Type: Application
    Filed: January 26, 2012
    Publication date: July 26, 2012
    Applicant: Niigata University
    Inventors: Takayoshi SHIMOHATA, Lawrence M. KAUVAR