Abstract: The present invention provides a method for selecting a cancer patient for whom a combination therapy with a retinoid and a cancer treatment agent is effective, which comprises a step of selecting a cancer patient having a malignant tumor with the infiltration of cancer-associated fibroblasts in the stroma. In addition, the present invention provides a medicament which comprises a cancer patient having a malignant tumor with the infiltration of cancer-associated fibroblasts in the stroma is a subject and is administered in combination of a retinoid and a cancer therapeutic agent.

Abstract: A steering control device is applied to a steer-by-wire system in which a steering mechanism and a turning mechanism are mechanically separated. The steering control device applied to the steer-by-wire system controls a drive of a steering motor that functions as a reaction motor that applies reaction torque to a steering wheel. A steering wheel lock calculating unit of the steering control device performs a steering wheel lock drive control for calculating a drive command so as to output a lock torque for maintaining a rotation stop state of the steering wheel by energizing the steering motor when a predetermined condition is satisfied while a vehicle is parked or stopped. A power converter converts power supply electric power according to the drive command calculated by the steering wheel lock calculating unit and supplies the electric power to the steering motor.

Abstract: The purpose of the present invention is to provide: a novel triazole silane compound and a method for synthesizing the same, and a silane coupling agent containing the triazole silane compound as a component; and a surface treatment solution, a surface treatment method, and a method for bonding two different materials, which use said triazole silane compound.

Abstract: A circuit board includes a plurality of first insulating base materials and a plurality of second insulating base materials that are alternately laminated, a first metal layer being formed into a pattern shape on a first surface of the first insulating base material, and a second metal layer being formed into a pattern shape on a second surface of the first insulating base material. The first metal layer is formed into a trapezoidal shape that is large in diameter on a first surface side of the first insulating base material. The second metal layer is formed into a trapezoidal shape that is large in diameter on a second surface side of the first insulating base material. The first metal layers and the second metal layers are laminated in such a manner that the trapezoidal shapes are alternately oriented.

Abstract: The present invention enables simple securing of an article to be transported without requiring provision of dedicated fixtures to securing surface. A securing aid, according to the present invention, which aids in securing an article to be transported to a securing surface of a transporting means carrying out the transportation, the securing aid comprising: a first fastening structure unit for fastening to the article to be transported; and part to be pressed which is pressed by a lashing member in a state of being pressed against the securing surface by the lashing member, wherein the first fastening structure unit is fastened to the article to be transported by working with a third fastening structure unit disposed below the article to be transported.

Abstract: An electric mileage estimation apparatus includes a storage device and a hardware processor connected to the storage device. The storage device stores information in which traveling history information is associated with an electric mileage of traveling. The traveling history includes a characteristic of a driver. The hardware processor acquires information about a traveling schedule including a characteristic of a driver. The hardware processor calculates an electric mileage estimation value on the basis of the information about the traveling schedule and parameters calculated from the information stored in the storage device. The hardware processor outputs information based on the electric mileage estimation value.

Abstract: Provided herein are methods for hydroisomerization of a hydrocarbon feedstock comprising contacting the hydrocarbon feedstock with hydrogen and a catalyst to yield a hydrocarbon product having an increase in branched hydrocarbons relative to the hydrocarbon feedstock. The present catalysts comprise a heteroatom-doped Beta zeolite having a trivalent cation as a framework metal oxide, an extra-framework species comprised of cerium and/or cobalt, and from 0.01 to 1.5 wt. % of a group VIII or VIB metal, or a combination thereof.

Abstract: Provided herein are methods for hydroisomerization of a hydrocarbon feedstock comprising contacting the hydrocarbon feedstock with hydrogen and a catalyst to yield a hydrocarbon product having an increase in branched hydrocarbons relative to the hydrocarbon feedstock. The present catalysts comprise a heteroatom-doped Beta zeolite having a trivalent cation as a framework metal oxide, an extra-framework species comprised of cerium and/or cobalt, and from 0.01 to 1.5 wt. % of a group VIII or VIB metal, or a combination thereof.

Abstract: Provided herein are methods for hydroisomerization of a hydrocarbon feedstock comprising contacting the hydrocarbon feedstock with hydrogen and a catalyst to yield a hydrocarbon product having an increase in branched hydrocarbons relative to the hydrocarbon feedstock. The present catalysts comprise a heteroatom-doped Beta zeolite having a trivalent cation as a framework metal oxide, an extra-framework species comprised of cerium and/or cobalt, and from 0.01 to 1.5 wt. % of a group VIII or VIB metal, or a combination thereof.

Abstract: An industrial robot includes: a first-member and a second-member that are rotatable about a particular axis and that each have a hollow portion extending along the axis; a cylindrical member inserted into the hollow portions along the axis, and fixed to the first-member; and a wire disposed in a cylindrical gap between the cylindrical member, the first-member, and the second-member, the wire having a length that enables rotation between the first-member and the second-member and having one end fixed to the first-member and another end fixed to the second-member. The second-member includes a first-portion rotatably supported by the first-member, a second-portion that fixes the end of the wire, and a third portion serially connected between the second-portion and the first-portion, and the third portion has an inner circumferential surface that faces the gap and has been subjected to a friction reducing process.

Abstract: An industrial robot includes: a first-member and a second-member that are rotatable about a particular axis and that each have a hollow portion extending along the axis; a cylindrical member inserted into the hollow portions along the axis, and fixed to the first-member; and a wire disposed in a cylindrical gap between the cylindrical member, the first-member, and the second-member, the wire having a length that enables rotation between the first-member and the second-member and having one end fixed to the first-member and another end fixed to the second-member. The second-member includes a first-portion rotatably supported by the first-member, a second-portion that fixes the end of the wire, and a third portion serially connected between the second-portion and the first-portion, and the third portion has an inner circumferential surface that faces the gap and has been subjected to a friction reducing process.

Abstract: In one embodiment, a plant control apparatus is configured to control a power generating plant that includes a gas turbine configured to be driven by a gas, an exhaust heat recovery boiler configured to generate steam by using heat of an exhaust gas from the gas turbine, a temperature reducing apparatus configured to cool, through a cooling medium, the steam generated by the exhaust heat recovery boiler, and a steam turbine configured to be driven by the steam cooled by the temperature reducing apparatus. The plant control apparatus includes an output controller configured to control output of the gas turbine, and a temperature reduction controller configured to control a cooling operation of the steam by the temperature reducing apparatus while the output controller controls the output of the gas turbine.

Abstract: Even if the ratio between blue and green components of illumination light is changed, a plurality of types of blood vessels at different depths are reliably distinguished. A blue signal B, a green signal G, a red signal R is obtained by imaging the subject using a color CCD 44. A B/G image having a B/G ratio is generated. A superficial blood vessel extraction image is obtained by extracting a pixel, in which the B/G ratio is equal to or less than a boundary value Ls between the mucous membrane and the superficial blood vessel, from the B/G image. A medium-deep blood vessel extraction image is obtained by extracting a pixel, in which the B/G ratio is equal to or greater than a boundary value Ld between the mucous membrane and the medium-deep blood vessel. The boundary values Ls and Ld differ depending on the light amount ratio.

Abstract: An observation object is imaged under irradiation with oxygen saturation level measurement light to obtain a first image signal, and the observation object is imaged under irradiation with white light to obtain a second image signal. A normal light image is produced from the second image signal. An oxygen saturation level is calculated from the first and second image signals. The calculated oxygen saturation level is imaged in an oxygen saturation image. By superimposing the normal light image on the oxygen saturation image, an emphasized oxygen saturation image is produced. In the emphasized oxygen saturation image, an abnormal area in which a calculation result of the oxygen saturation level is likely to be abnormal is emphasized by its brightness. The produced emphasized oxygen saturation image is displayed on a display device.

Abstract: An endoscope system comprising an image signal acquisition unit acquiring an image signal by imaging a subject, and an irregularity image generation unit generating an irregularity image by extracting information of irregularities on the subject, the irregularity image generation unit includes a microstructure image generation section generating a microstructure image as the irregularity image by extracting a microstructure of a body tissue surface layer from the image signal, the image signal including image signals of a plurality of colors having information of different wavelength components, the microstructure image generation section includes a first brightness signal generation section generating a brightness signal showing an average brightness of the subject based on the image signals of the plurality of colors, and a first image generation section generating the microstructure image by extracting a pixel region, in which a pixel value exceeds a fixed threshold value, of the brightness signal as a mic

Abstract: In one embodiment, a plant control apparatus is configured to control a power generating plant that includes a gas turbine configured to be driven by a gas, an exhaust heat recovery boiler configured to generate steam by using heat of an exhaust gas from the gas turbine, a temperature reducing apparatus configured to cool, through a cooling medium, the steam generated by the exhaust heat recovery boiler, and a steam turbine configured to be driven by the steam cooled by the temperature reducing apparatus. The plant control apparatus includes an output controller configured to control output of the gas turbine, and a temperature reduction controller configured to control a cooling operation of the steam by the temperature reducing apparatus while the output controller controls the output of the gas turbine.

Abstract: An endoscopic device that irradiates a plurality of illuminating lights having different spectrums from each other onto a subject at a front edge of an endoscope inserting module and captures the subject to obtain an observation image, includes an illuminating module that generates the plurality of illuminating lights, an imaging module that captures the subject and outputs an image signal of the observation image, a light intensity ratio control module that controls the illuminating module to irradiate the plurality of illuminating lights onto the subject with a set light intensity ratio by setting the light intensity ratio of the plurality of illuminating lights for every observation image, and a color tone correcting module that corrects the color tone of the image signal so as to obtain the observation image with substantially a same color tone even though the light intensity ratio is changed.

Abstract: Broadband light BB and narrowband light NB are simultaneously irradiated to a subject. A blue signal B, a green signal G, and a red signal R are obtained by imaging the subject using a color CCD 33. A base image is generated from the signals B, G, and R of three colors. A B/G image having a B/G ratio is generated. A superficial blood vessel extraction image is obtained by extracting a pixel, in which the B/G ratio is equal to or less than a boundary value Ls between the mucous membrane and the superficial blood vessel, from the B/G image. A medium-deep blood vessel extraction image is obtained by extracting a pixel, in which the B/G ratio is equal to or greater than a boundary value Ld between the mucous membrane and the medium-deep blood vessel. The boundary values Ls and Ld differ depending on each observation mode.

Abstract: A blue signal B, a green signal G, and a red signal R are obtained by imagining a subject illuminated with white light W using a color CCD 44. Based on these signals B, G, and R, a normal light image in which a wavelength component of a visible light region is included is generated. Based on the signals B, G, and R, a brightness signal I ((B+G+R)/3) showing the average brightness of the subject is generated. A pixel region exceeding the fixed threshold value Th1 of the brightness signal I is extracted as a superficial microstructure P, such as a pit pattern. A microstructure enhancement image 72 is generated by combining the normal light image with a superficial microstructure image 70 obtained by extracting the superficial microstructure P. The generated microstructure and blood vessel enhancement image 72 is displayed on a monitor 14.

Abstract: An oxygen saturation level of hemoglobin in blood is correctly acquired without lowering a frame rate. A subject body illuminated with white light W is imaged by a color CCD to obtain signals Bs1, Gs1 and Rs1. The subject body is illuminated with blue narrow band light BN of which absorption coefficient is changed by a change in the oxygen saturation level of the hemoglobin in blood, and imaged by the color CCD to obtain signals Bs2, Gs2 and Rs2. The signal Bs2 is divided by the signal Gs1 to determine a normalized signal Bs2/Gs1. The oxygen saturation level of blood vessels of the surface of body tissue is obtained according to the normalized signal Bs2/Gs1. The oxygen saturation level is visualized in a pseudo color, to form an oxygen saturation level image.