Patents by Inventor Takayuki Nishijyo

Takayuki Nishijyo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • and process for prodcuing protein wtih use of the microbe as host
    Patent number: 7655452
    Abstract: Brevibacillus choshinensis is characterized in that its extracellular proteolytic activity is extremely low and its protein secretion productivity is excellent, but it is desired that not only the extracellular proteolytic activity of the strain is further reduced but also the intracellular proteolytic activity thereof is further reduced. When Brevibacillus choshinensis is used as a host for the production of protein pharmaceuticals and the like, it is also desired that it does not form spores and is readily sterilized. The above problems have been solved by inactivating the sporulation-associated gene thereof and by cloning and inactivating the extracellular and intracellular protease genes thereof.
    Type: Grant
    Filed: November 8, 2004
    Date of Patent: February 2, 2010
    Assignee: Higeta Shoyu Co., Ltd.
    Inventors: Hiroshi Hanagata, Takayuki Nishijyo