Abstract: A orally disintegrating tablet is obtained by tableting fine granules showing controlled release of lansoprazole and an additive, which is capable of suppressing breakage of the fine granules during tableting, and can control the release of lansoprazole for a long time, and can maintain a therapeutically effective concentration for a prolonged time, and shows superior disintegration property in the oral cavity.

Abstract: A belt-like material-feeding apparatus for continuously feeding a belt-like material to a treating unit, comprises a splicing unit which splices a second belt-like material to a first belt-like material being fed to the treating unit to thereby switch the belt-like material being fed to the treating unit from the first belt-like material into the second belt-like material, an accumulating unit which is arranged between the splicing unit and the treating unit and is capable of temporarily accumulating the belt-like material, and a control unit which, prior to the splicing operation of the splicing unit, increases the amount of accumulation of the belt-like material to be larger than the amount of accumulation of the belt-like material during the steady operation and, during the splicing operation, releases the belt-like material from the accumulating unit to decrease the amount of accumulation of the belt-like material.

Abstract: A belt-like material-feeding apparatus for continuously feeding a belt-like material to an intermittently-treating unit comprises a splicing unit which splices a second belt-like material to a first belt-like material being fed to the intermittently-treating unit to thereby switch the belt-like material being fed to the intermittently-treating unit from the first belt-like material into the second belt-like material, and a control unit for controlling the splicing timing of the splicing unit based upon the treating timing of the intermittently-treating unit. When it is judged that a splicing region formed between the first belt-like material and the second belt-like material by the splicing operation of the splicing unit, is going to be treated by the intermittently-treating unit, the control unit controls the splicing unit so as to retard the splicing operation.

Abstract: Provided is a tablet having a high content of 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-4-fluorobenzonitrile (compound (A)) or a salt thereof as a pharmaceutically active component. A tablet containing compound (A) or a salt thereof, and a fluidizer, which has a compound (A) content of 35-50 weight %.

Abstract: An apparatus 100 of the present invention for manufacturing an absorbent article which includes a liquid-permeable topsheet, a liquid-impermeable backsheet and an absorber provided between the topsheet and the backsheet, is provided with a lower press roller 110B which presses outer edge areas 81 which correspond to outer edges of the extended portions 50 of a continuous body constituted by the plurality of continuous sheets. The lower press roller 110B is provided with a plurality of rear end protrusions 115 which protrude outward in a radial direction of the roller and press rear end inclined areas 81S which correspond to the outside-to-inside inclined areas of the outer edge areas 81. An extending direction LD2 of the rear end protrusions 115 differ from an extending direction of a rear end outline 87 extending along the shapes of rear end inclined portions 50B in the rear end inclined areas 81S.

Abstract: The present invention provides a method for improving absorbability of the active ingredient of an enteric polymer coated preparation, which includes using an organic acid.

Abstract: A dithiolphosphoric acid ester of the formula, ##STR1## wherein R is methyl or ethyl group, and when R is methyl group, A is iso-butyl, sec-butyl or tert-butyl group and B is methyl, ethyl or n-propyl group, when R is ethyl group and A is sec-butyl or tert-butyl group, B is methyl group, and when R is ethyl group and A is iso-butyl group, B is methyl, ethyl or n-propyl group, which is useful as a soil pesticidal composition for pests in soil.

Abstract: A trithiophosphoric acid ester of the formula: ##STR1## wherein R is lower alkyl group, and R.sub.1 and R.sub.2 are different from each other, R.sub.1 is C.sub.1 -C.sub.4 alkyl group and R.sub.2 is isobutyl, sec-butyl or tert-butyl group, which is useful as a soil pesticidal composition for pests in soil.

Abstract: A trithiophosphoric acid ester of the formula; ##STR1## wherein R.sub.1 is methyl or ethyl group, which is useful as a soil pesticidal composition for pests in soil.

Abstract: A dithiolphosphoric acid ester of the formula, ##STR1## wherein A is sec-butyl or tert-butyl group, and B is iso-propyl, n-butyl, iso-butyl, sec-butyl or tert-butyl group, which is useful as a soil pesticidal composition for pests in soil.

Abstract: Phosphoro-thioates or dithioates of the formula (I), ##STR1## wherein R is a C.sub.1 -C.sub.3 alkyl group, R.sub.1 is a C.sub.1 -C.sub.3 alkoxy, C.sub.1 -C.sub.4 alkylamino or allylamino group, R.sub.2 is a halogen atom, a C.sub.1 -C.sub.4 alkoxy or C.sub.1 -C.sub.3 alkyl group, R.sub.3 is a hydrogen or halogen atom or a C.sub.1 -C.sub.3 alkyl group, R.sub.4 is a C.sub.1 -C.sub.3 alkyl group, and X is an oxygen or sulfur atom, provided that when R.sub.1 is a C.sub.1 -C.sub.4 alkylamino or allylamino group, X is an oxygen atom, a process for producing phosphoro-thioates or dithioates of the formula (I) characterized by condensing a pyrimidine of the formula (II), ##STR2## wherein Y is a halogen atom, and R.sub.2, R.sub.3 and R.sub.4 are as defined above, with a thio- or dithio-phosphate of the formula, ##STR3## wherein M is an alkali metal atom or an ammonium group, and R, R.sub.

Abstract: Organophosphorus esters of the formula (I), ##STR1## wherein R is a C.sub.1 -C.sub.2 alkyl group, R.sub.1 is a C.sub.1 -C.sub.2 alkyl, C.sub.1 -C.sub.2 alkoxy, C.sub.1 -C.sub.4 alkylamino, phenyl or phenoxy group, R.sub.2 and R.sub.3, which may be the same or different, are each a C.sub.1 -C.sub.5 alkyl or methoxy C.sub.2 -C.sub.3 alkyl group and X is an oxygen or sulfur atom, a method for producing organophosphorus esters of the formula (I) characterized by condensation reaction of s-triazines of the formula, ##STR2## wherein M is a potassium or sodium atom and R.sub.2 and R.sub.3 are as defined above, with a halogenated compound of the formula, ##STR3## wherein Y is a halogen atom and R, R.sub.1 and X are as defined above, and an insecticide, acaricide and/or nematocide characterized by containing organophosphorus esters of the formula (I) as an active ingredient.

Abstract: Pyrimidin-4-yl-phosphorothionates of the formula (I), ##STR1## wherein R is a C.sub.1 -C.sub.2 alkyl group, R.sub.1 is a C.sub.1 -C.sub.2 alkoxyl or C.sub.1 -C.sub.4 alkylamino group, R.sub.2 and R.sub.3, which may be the same or different, are each a halogen atom, a C.sub.1 -C.sub.3 alkoxyl or methylmercapto group, and X is an oxygen or sulfur atom; a process for producing pyrimidin-4-yl-phosphorothionates of the formula (I) characterized by condensing a 4-hydroxypyrimidine of the formula (II), ##STR2## wherein R.sub.2 and R.sub.3, which may be the same or different, are each a halogen atom, a C.sub.1 -C.sub.3 alkoxyl or methylmercapto group, with a halogen compound of the formula, ##STR3## wherein R is a C.sub.1 -C.sub.2 alkyl, R.sub.1 is a C.sub.1 -C.sub.2 alkoxyl or C.sub.1 -C.sub.