Abstract: The present invention provides an easy and accurate method for obtaining information regarding a quantity of DNA included in a sample used for analyzing a methylation of a target DNA, comprising steps of: treating a biological sample containing DNA including the target DNA with a non-methylated cytosine converting agent for converting non-methylated cytosine of the DNA into another base; and obtaining information regarding a quantity of DNA included in the sample treated in the treating step by using an oligonucleotide complementary to a cytosine-free region of the target DNA.

Abstract: Disclosed is a method for producing a synthetic resin mold package at high yield from which package a pair of the surface of an internal device is exposed. A to-be-exposed part of the surface of the internal device composed of an insulating substrate (2) and thin film electrodes (4, 5) and an insulating protective film (6) formed on the substrate is covered with a coating agent (42), and a die pad portion (8) is bonded to the back surface of the internal device. After placing the thus-obtained structure in a mold consisting of a lower mold (46) and an upper mold (48), a pin (50) is inserted into the mold so that the front end of the pin is pressed against the die pad portion (8), thereby keeping the surface of the coating agent (42) pressed against the inner surface of the upper mold (48). Then, a synthetic resin (52) is injected into the mold and cured therein. The thus-obtained resin sealed body is taken out from the mold, and the coating agent (42) is removed from the resin sealed body.

Abstract: There is provided an identification device capable of accurately, rapidly, and easily identifying a hydrocarbon-based liquid and alcohol-based liquid. An identification sensor unit (2) is arranged to face a flow passage (20) of a liquid to be measured and includes a liquid type detection unit with indirect heating (21) having a heating body and a temperature-sensitive body, and a liquid temperature detecting unit (22) for detecting the temperature of the liquid to be measured. The identification device further includes an identification calculation unit for applying a single pulse voltage to the heating body of the liquid type detection unit (21) so as to generate heat and identifying the liquid to be measured according to an output of a liquid type detection circuit formed by the temperature-sensitive body of the liquid type detecting unit (21) and the liquid temperature detection unit.

Abstract: A flow rate/liquid type detecting method for detecting the flow rate of a fluid and, at the same time, detecting any one of or both the type of the fluid and the concentration of the fluid, characterized in that, by using a flow rate/liquid type detecting apparatus comprising: a main passage through which a fluid to be detected flows, an auxiliary passage branched from the main passage, and a flow rate/liquid type detecting sensor device provided in the auxiliary passage, is provided, and in conducting any one of or both the detection of the type of the fluid and the detection of the concentration of the fluid, the auxiliary passage opening/closing valve is closed, and the fluid is allowed to temporarily stay within the flow rate/liquid type detecting sensor device to conduct any one of or both the detection of the liquid type and the detection of the concentration, and in detecting the flow rate of the fluid detected, the auxiliary passage opening/closing valve is opened to allow the fluid to flow into the f

Abstract: A urea concentration identification device comprising a concentration identification sensor unit (2) and a support unit (4) attached at the bottom end thereof with this sensor unit and provided at the top end thereof with a mounting unit (4a) to a urea solution tank opening. The concentration identification sensor unit (2) has an indirectly-heated concentration detector and liquid temperature detector provided with metal fins (21c),(22c), respectively, for heat-exchanging with urea solution. The concentration identification sensor unit (2) is provided with a cover member (2d) that forms an opposite-ends-opened urea solution induction passage so as to surround the metal fins (21c),(22c), and an enclosure (2e) that forms communication holes (26),(27) in the top and bottom end plate thereof (2e1),(2e2).

Abstract: The present invention provides a novel marker capable of accurately diagnosing the lymph node metastasis of stomach cancer. An mRNA, or a fragment thereof, coding for at least one protein selected from TFF1, AGR2, PRSS8, MUC1, MUC4 and MUC17 can be useful as a lymph node metastasis marker.

Abstract: A flow rate/liquid type detecting method for detecting the flow rate of a fluid and, at the same time, detecting any one of or both the type of the fluid and the concentration of the fluid, characterized in that: by using a flow rate/liquid type detecting apparatus comprising a main passage through which a fluid to be detected flows, an auxiliary passage branched from the main passage, and a flow rate/liquid type detecting sensor device provided in the auxiliary passage, is provided, and in conducting any one of or both the detection of the type of the fluid to be detected and the detection of the concentration of the fluid to be detected, an auxiliary passage opening/closing valve is closed, and the fluid to be detected is allowed to temporarily stay within the flow rate/liquid type detecting sensor device to conduct any one of or both the detection of the liquid type and the detection of the concentration, and in detecting the flow rate of the fluid to be detected, the auxiliary passage opening/closing valv

Abstract: Apparatus and method for identifying type and distillation properties of light oil. A pulse voltage is applied for a predetermined period of time to a liquid type identification sensor heater comprising a heater and an identification liquid temperature sensor provided in the vicinity of the heater; the light oil to be identified is heated by the heater; and the liquid type is identified with a voltage output difference V0, corresponding to a temperature difference between the initial temperature and the peak temperature of the identification liquid temperature sensor.

Abstract: The object of the present invention is to provide a novel marker for a correct diagnosis of lymph node metastasis of breast cancer. This object is attained by a marker for judging lymph node metastasis of tumor cells derived from breast cancer, the marker including mRNA of the gene encoding Forkhead box A1 (FOXA1) or a fragment thereof.

Abstract: A medical simulation system has a replacing section for replacing at least a part of a plurality of biological function state values represented by the biological model and a simulating section for generating post-replacement simulated biological response on the basis of the biological model which reflects the replaced value.

Abstract: The present invention relates to a primer and method for detecting lymph node metastasis of a cancer cell derived from a colon cancer by detecting a marker in a sample prepared from a lymph node obtained from a living body, wherein the marker is a mRNA or a fragment of the mRNA, the mRNA being transcribed from a gene coding a specific protein.

Abstract: There is provided an identification device capable of accurately, rapidly, and easily identifying a hydrocarbon-based liquid and alcohol-based liquid. An identification sensor unit (2) is arranged to face a flow passage (20) of a liquid to be measured and includes a liquid type detection unit with indirect heating (21) having a heating body and a temperature-sensitive body, and a liquid temperature detecting unit (22) for detecting the temperature of the liquid to be measured. The identification device further includes an identification calculation unit for applying a single pulse voltage to the heating body of the liquid type detection unit (21) so as to generate heat and identifying the liquid to be measured according to an output of a liquid type detection circuit formed by the temperature-sensitive body of the liquid type detecting unit (21) and the liquid temperature detection unit.

Abstract: A medical simulation system includes a biological response inputting section that receives input of biological response information indicating an actual biological response of biological body, a biological model generating section that generates a biological model for reproduction of simulated response simulating the actual biological response, a pathologic condition characteristics acquiring section that acquires pathologic condition characteristics information indicating characteristics of pathologic condition of the biological body based on the generated biological model, and an outputting section that outputs the biological response information and the pathologic condition characteristics information.

Abstract: A urea concentration identification device comprising a concentration identification sensor unit (2) and a support unit (4) attached at the bottom end thereof with this sensor unit and provided at the top end thereof with a mounting unit (4a) to a urea solution tank opening. The concentration identification sensor unit (2) has an indirectly-heated concentration detector and liquid temperature detector provided with metal fins (21c),(22c), respectively, for heat-exchanging with urea solution. The concentration identification sensor unit (2) is provided with a cover member (2d) that forms an opposite-ends-opened urea solution induction passage so as to surround the metal fins (21c), (22c).

Abstract: The types of gasolines having different distillation characteristics and various compositions are identified accurately and rapidly. A pulse voltage is applied for a predetermined time to a liquid type identifying sensor heater including a heater and an identifying liquid temperature sensor provided in the vicinity of the heater and an identified gasoline is heated by the heater and the liquid type is identified with a voltage output difference V0 corresponding to a temperature difference between an initial temperature and a peak temperature in the identifying liquid temperature asensor. Furthermore, a gasoline is introduced between electrodes of an alcohol concentration detecting sensor, and a change in a specific inductive capacity of the gasoline between the electrodes is measured with an oscillation frequency thereby detecting an alcohol concentration in the gasoline.

Abstract: The types of gasolines having different distillation characteristics and various compositions are identified accurately and rapidly. A pulse voltage is applied for a predetermined time to a liquid type identifying sensor heater including a heater and an identifying liquid temperature sensor provided in the vicinity of the heater. Then, a gasoline to be identified is heated by the heater, and a liquid type is identified with a voltage output difference V0 corresponding to a temperature difference between an initial temperature and a peak temperature in the identifying liquid temperature sensor.

Abstract: The types of gasolines having different distillation characteristics and various compositions are identified accurately and rapidly. A pulse voltage is applied for a predetermined time to a liquid type identifying sensor heater including a heater and an identifying liquid temperature sensor provided in the vicinity of the heater and an identified gasoline is heated by the heater and the liquid type is identified with a voltage output difference V0 corresponding to a temperature difference between an initial temperature and a peak temperature in the identifying liquid temperature sensor. Furthermore, a gasoline is introduced between electrodes of an alcohol concentration detecting sensor, and a change in a specific inductive capacity of the gasoline between the electrodes is measured with an oscillation frequency thereby detecting an alcohol concentration in the gasoline.

Abstract: A flow rate/liquid type detecting method for detecting the flow rate of a fluid and, at the same time, detecting any one of or both the type of the fluid and the concentration of the fluid, characterized in that: by using a flow rate/liquid type detecting apparatus comprising; a main passage through which a fluid to be detected flows, an auxiliary passage branched from said main passage, and a flow rate/liquid type detecting sensor device provided in said auxiliary passage, is provided, and in conducting any one of or both the detection of the type of said fluid to be detected and the detection of the concentration of said fluid to be detected, said auxiliary passage opening/closing valve is closed, and said fluid to be detected is allowed to temporarily stay within said flow rate/liquid type detecting sensor device to conduct any one of or both the detection of the liquid type and the detection of the concentration, and in detecting the flow rate of the fluid to be detected, said auxiliary passage opening/cl

Abstract: Apparatus and method for identifying type and distillation properties of light oil. A pulse voltage is applied for a predetermined period of time to a liquid type identification sensor heater comprising a heater and an identification liquid temperature sensor provided in the vicinity of the heater; the light oil to be identified is heated by the heater; and the liquid type is identified with a voltage output difference V0, corresponding to a temperature difference between the initial temperature and the peak temperature of the identification liquid temperature sensor.

Abstract: A flowmeter for achieving a fluid flow rate value by using calibration curves on the basis of the output of a detection circuit using a bridge circuit (73) containing as constituent resistors respective temperature sensing elements of a flow rate detector containing a heating element (33) and a fluid temperature detector in an indirectly heated type flow rate sensor unit. The bridge circuit (73) varies the circuit characteristic value in plural steps by a multiplexer (731) for selectively connecting the output terminal and any one of the connection terminals between the in-series connected resistors. Plural calibration curves are provided in association with the steps of the circuit characteristic value, and any one of the plural calibration curves is selected in accordance with the step of the circuit characteristic value selected by the multiplexer (731).