Abstract: Titanium dioxide/organic polymer hybrid materials for artificial bone produced by forming titania gel on the surface of a substrate made of an organic polymer and treating the titania gel with hot water or an aqueous solution of an acid to convert the titania gel into a titanium dioxide membrane on which apatite having such a Ca/P atomic ratio as to constitutes the bone of an mammal can be formed from the body fluid thereof.

Abstract: A novel polymeric material for artificial bones, comprising a solid or gel-form base containing, as the main component, either a polysaccharide having carboxyl groups or their derivatives, or a polysaccharide having carboxyl groups or their derivatives, introduced into it, which also has calcium ions bonded thereto, and shows excellent ability to form apatite.

Abstract: A novel polymeric material for artificial bones, comprising a solid or gel-form base containing, as the main component, either a polysaccharide having carboxyl groups or their derivatives, or a polysaccharide having carboxyl groups or their derivatives, introduced into it, which also has calcium ions bonded thereto, and shows excellent ability to form apatite.

Abstract: Anticoagulative high-molecular composition which comprises a cellulosic polyelectrolyte complex formed from a polycationic cellulose derivative such as a quaternary ammonium salt of hydroxyalkyl cellulose, and a polyanionic cellulose such as sodium cellulose glycolate, which is used in the field of medical instruments or devices.

Abstract: This invention concerns a production process of an antithrombogenic and antiadhesive material which can favorably be used as artificial blood vessels, artificial valves, grafting patches for cardiovascular organs, artificial heart catheters and so on. The gist of this invention is constructed substantially of subjecting glycidyltrialkylammonium halide such as glycidyltrimethylammonium chloride to the reaction with a material comprising pure collagen or collagen and other components like mucopolysaccharide in order to introduce a cationic quaternary functional group in collagen molecules of the material and then subjecting heparin to the ionic combination with the cationic functional group introduced.