Patents by Inventor Takefumi YAMASHITA

Takefumi YAMASHITA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CONJUGATE OF BIOTIN-MODIFIED DIMER AND PHTHALOCYANINE DYE
    Publication number: 20230106135
    Abstract: [Object] It is an object of the present invention to provide a conjugate of a biotin-modified dimer and a phthalocyanine dye, which is used in photoimmunotherapy. [Means for Solution] A compound represented by the following formula (1) or a salt thereof: wherein X represents a substituent having a hydrophilic group, a cationic group or an amino group at the terminus thereof, or —OH, and other groups have the meanings as defined in the description.
    Type: Application
    Filed: April 22, 2021
    Publication date: April 6, 2023
    Applicants: THE UNIVERSITY OF TOKYO, SAVID THERAPEUTICS INC.
    Inventors: Motomu KANAI, Kenzo YAMATSUGU, Toshifumi TATSUMI, Kazuki TAKAHASHI, Tatsuhiko KODAMA, Akira SUGIYAMA, Takefumi YAMASHITA, Masanobu TSUKAGOSHI, Yuzo TODA, Junji NISHIGAKI
  • FUSED PROTEIN OF AN ANTIBODY WHICH RECOGNIZES CANCER-CELLS AND A STREPTAVIDIN MUTANT
    Publication number: 20220348681
    Abstract: [Object] To provide a fusion protein of an antibody that recognizes cancer cells and a mutant streptavidin, which is for use in the treatment or diagnosis of cancer. [Means for Solution] A fusion protein comprising a protein-recognizing substance and the amino acid sequence as set forth in SEQ ID NO: 19 that is fused with the protein-recognizing substance.
    Type: Application
    Filed: April 22, 2021
    Publication date: November 3, 2022
    Applicants: THE UNIVERSITY OF TOKYO, SAVID THERAPEUTICS INC.
    Inventors: Toshiya TANAKA, Tatsuhiko KODAMA, Takefumi YAMASHITA, Motomu KANAI, Kenzo YAMATSUGU, Toshifumi TATSUMI, Takeshi KAWAMURA, Akira SUGIYAMA, Masanobu TSUKAGOSHI, Yuzo TODA, Junji NISHIGAKI
  • FUSION PROTEIN OF ANTIBODY THAT RECOGNIZES CANCER CELLS AND MUTANT STREPTAVIDIN
    Publication number: 20220073641
    Abstract: It is an object of the present invention to provide a fusion protein of an antibody that recognizes cancer cells and a mutant streptavidin, which is for use in the treatment or diagnosis of cancer. According to the present invention, provided is a fusion protein having the amino acid sequence as set forth in SEQ ID NO: 2 or SEQ ID NO: 7, a linker sequence, and the amino acid sequence as set forth in SEQ ID NO: 1 (provided that the amino acid sequence portion consisting of 6 histidine residues at the C-terminus thereof may be partially or entirely deleted), from the N-terminal side to the C-terminal side, in this order.
    Type: Application
    Filed: December 27, 2019
    Publication date: March 10, 2022
    Applicants: The University of Tokyo, SAVID THERAPEUTICS INC.
    Inventors: Toshiya TANAKA, Tatsuhiko KODAMA, Takefumi YAMASHITA, Motomu KANAI, Kenzo YAMATSUGU, Toshifumi TATSUMI, Kazuki TAKAHASHI, Shumpei ISHIKAWA, Akira SUGIYAMA, Masanobu TSUKAGOSHI
  • CONJUGATE OF BIOTIN-MODIFIED DIMER AND PHTHALOCYANINE DYE
    Publication number: 20220016245
    Abstract: It is an object of the present invention to provide a conjugate of a biotin-modified dimer and a phthalocyanine dye, which is used in photoimmunotherapy. The present invention provides a conjugate of a compound represented by the following formula (1) or a salt thereof and a phthalocyanine dye: wherein the meaning of each of symbols is as defined in the specification.
    Type: Application
    Filed: August 8, 2019
    Publication date: January 20, 2022
    Applicants: The University of Tokyo, SAVID THERAPEUTICS INC.
    Inventors: Motomu KANAI, Kenzo YAMATSUGU, Toshifumi TATSUMI, Kazuki TAKAHASHI, Tatsuhiko KODAMA, Toshiya TANAKA, Takefumi YAMASHITA, Akira SUGIYAMA, Masanobu TSUKAGOSHI