Patents by Inventor Takehiko Yoko-O

Takehiko Yoko-O has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PRODUCTION METHOD FOR USEFUL SUBSTANCE
    Publication number: 20190376104
    Abstract: The present invention provides a method, of producing a useful substance, including secreting and producing a useful substance in broth by yeast contained in the broth, the yeast being a Saccharomyces strain, the broth containing a compound (A) represented by a formula (1), the compound (A) having an HLB value of 0.1 to 16 and a number average molecular weight of 200 to 30000, the weight percentage of the compound (A) based on the weight of the broth being 0.0001 to 10 wt %: HO—(A1O)m1-(A2O)m2-(A3O) m3—H ??(1) wherein A1O, A2O, and A3O each independently represent a C2-C4 oxyalkylene group; A1O and A2O have different structural formulas, A2O and A3O have different structural formulas; and m1, m2, and m3 each respectively represent the average number of moles of A1O, A2O, and A3O added, and are each independently a number in the range of 1 to 600.
    Type: Application
    Filed: February 28, 2018
    Publication date: December 12, 2019
    Applicant: SANYO CHEMICAL INDUSTRIES, LTD.
    Inventors: Masumi UEDA, Mutsumi NAKANISHI, Yasunori CHIBA, Takehiko YOKO-O
  • METHOD FOR IMPROVED HIGH-LEVEL SECRETORY PRODUCTION OF PROTEIN
    Publication number: 20170211063
    Abstract: The object of the present invention is to provide a production system that is capable of high-level secretory production of a protein (and in particular, a protein with a complicated structure such as a structure with S—S bonds) in a host cell such as yeast and is suitable for industrial production with high safety that does not require explosion-proof facilities. The present invention provides a transformed yeast into which a chaperone gene has been introduced and in which the aox1 gene and/or the protease gene have been disrupted and a method for producing a protein involving the use of such transformed yeast.
    Type: Application
    Filed: July 29, 2015
    Publication date: July 27, 2017
    Applicant: Daiichi Sankyo Company, Limited
    Inventors: Koichi NONAKA, Takeshi SUZUKI, Masashi TSUDA, Satoshi BABA, Kimihisa ICHIKAWA, Yasunori CHIBA, Takehiko YOKO-O, Rie ITO
  • Lipid remodeling of GPI-anchored proteins
    Patent number: 7741087
    Abstract: This invention provides proteins and genes thereof involved in the GPI lipid remodeling process and, thereby and constructing a system for screening for useful substances such as anticancer agents and a system for detecting abnormalities in the GPI lipid remodeling process.
    Type: Grant
    Filed: August 7, 2007
    Date of Patent: June 22, 2010
    Assignee: National Institute of Advanced Industrial Science and Technology
    Inventors: Yoshifumi Jigami, Takehiko Yoko-O, Mariko Umemura, Morihisa Fujita
  • GENES AND PROTEINS INVOLVED IN LIPID REMODELING OF GPI-ANCHORED PROTEINS AND THE USE THEREOF
    Publication number: 20080233608
    Abstract: This invention provides proteins and genes thereof involved in the GPI lipid remodeling process and, thereby and constructing a system for screening for useful substances such as anticancer agents and a system for detecting abnormalities in the GPI lipid remodeling process.
    Type: Application
    Filed: August 7, 2007
    Publication date: September 25, 2008
    Inventors: Yoshifumi Jigami, Takehiko Yoko-O, Mariko Umemura, Morihisa Fujita