Patents by Inventor Takehiro Fukuzaki
Takehiro Fukuzaki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230242565Abstract: Provided are macrolide compounds for the treatment of infectious diseases. The macrolides disclosed herein include 14-membered ketolides and 14-15-membered azaketolides, and may comprise modified sugars which are desosamine analogues. The disclosed macrolides may have a bicyclic structure. Also provided are pharmaceutical compositions and methods of treating infectious diseases, and in particular, disease which results from Gram negative bacteria using the disclosed macrolides. This disclosure additionally provides methods of preparing the macrolides by a strategy that enables late-stage modification of the 6?-position of the sugar moiety, thereby allowing facile access to previously difficult-to-make macrolide compounds.Type: ApplicationFiled: April 4, 2023Publication date: August 3, 2023Inventors: Andrew G. Myers, Ziyang Zhang, Takehiro Fukuzaki, Udara Anulal Premachandra Ilandari Dewage, Senkara Rao Allu, Roger B. Clark, Jonathan F. Lawrence, Wesley Francis Austin, Xiben Li, Wenying Wang, Sushmita D. Lahiri, Yoshitaka Ichikawa
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Patent number: 11673910Abstract: Provided are macrolide compounds for the treatment of infectious diseases. The macrolides disclosed herein include 14-membered ketolides and 14-15-membered azaketolides, and may comprise modified sugars which are desosamine analogues. The disclosed macrolides may have a bicyclic structure. Also provided are pharmaceutical compositions and methods of treating infectious diseases, and in particular, disease which results from Gram negative bacteria using the disclosed macrolides. This disclosure additionally provides methods of preparing the macrolides by a strategy that enables late-stage modification of the 6?-position of the sugar moiety, thereby allowing facile access to previously difficult-to-make macrolide compounds.Type: GrantFiled: April 27, 2018Date of Patent: June 13, 2023Inventors: Andrew G. Myers, Ziyang Zhang, Takehiro Fukuzaki, Udara Anulal Premachandra Ilandari Dewage, Senkara Rao Allu, Roger B. Clark, Jonathan F. Lawrence, Wesley Francis Austin, Xiben Li, Wenying Wang, Sushmita D. Lahiri, Yoshitaka Ichikawa
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Publication number: 20230056354Abstract: According to one embodiment, an X-ray diagnostic apparatus includes an X-ray irradiator, a scatterer, a grid, and a detector. The X-ray irradiator irradiates X-rays. The scatterer is provided between the X-ray irradiator and an object, that scatters the irradiated X-rays. The grid is provided between the scatterer and the object, that transmits the scattered X-rays within a predetermined angular range. The detector detects X-rays transmitted through the object together with an incident angle of the X-rays.Type: ApplicationFiled: August 12, 2022Publication date: February 23, 2023Applicant: CANON MEDICAL SYSTEMS CORPORATIONInventors: Yoshimasa KOBAYASHI, Yasuhiro SUGAWARA, Seiichi NISHIZUKA, Takehiro FUKUZAKI, Daisuke SATO, Tatsuaki KODAKA, Akitoshi SATO, Tomio MAEHAMA
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Publication number: 20220306673Abstract: Provided are macrolide compounds for the treatment of infectious diseases. The macrolides disclosed herein include 14-membered ketolides and 14-15-membered azaketolides, and may comprise modified sugars which are desosamine analogues. The disclosed macrolides may have a bicyclic structure. Also provided are pharmaceutical compositions and methods of treating infectious diseases, and in particular, disease which results from Gram negative bacteria using the disclosed macrolides. This disclosure additionally provides methods of preparing the macrolides by a strategy that enables late-stage modification of the 6?-position of the sugar moiety, thereby allowing facile access to previously difficult-to-make macrolide compounds.Type: ApplicationFiled: April 27, 2018Publication date: September 29, 2022Inventors: Andrew G. Myers, Ziyang Zhang, Takehiro Fukuzaki, Udara Anulal Premachandra llandari Dewage, Senkara Rao Allu, Roger B. Clark, Jonathan F. Lawrence, Wesley Francis Austin, Xiben Li, Wenying Wang, Sushmita D. Lahiri, Yoshitaka Ichikawa
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Publication number: 20220185524Abstract: A wrap replacing apparatus according to the embodiments includes: an insertion port into which a medical device wrapped in a first bag is inserted; a peeler configured to peel off the first bag from the medical device inserted into the insertion port; a wrapper configured to wrap in a second bag the medical device from which the first bag is peeled off; and a take-out port from which the medical device wrapped in the second bag is taken out.Type: ApplicationFiled: December 15, 2021Publication date: June 16, 2022Applicant: Canon Medical Systems CorporationInventors: Yoshimasa KOBAYASHI, Yasuhiro SUGAWARA, Seiichi NISHIZUKA, Takehiro FUKUZAKI, Daisuke SATO, Tatsuaki KODAKA, Akitoshi SATO, Tomio MAEHAMA
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Patent number: 11266362Abstract: According to one embodiment, an X-ray detection unit for a wheelchair includes a container and an attachment portion coupled with the container. The container is configured to contain a flat X-ray detector. The attachment portion is configured to be detachably mounted to a part of the wheelchair in which a subject is seated, so that a detection plane of the X-ray detector in the container faces the subject.Type: GrantFiled: June 2, 2020Date of Patent: March 8, 2022Assignee: Canon Medical Systems CorporationInventors: Takehiro Fukuzaki, Masaharu Soya
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Publication number: 20220061788Abstract: The X-ray imaging system according to the present embodiment includes an X-ray tube, a holding assembly, a flying object, an X-ray detector, and processing circuitry, The X-ray tube is configured to emit X-rays. The holding assembly is configured to hold the X-ray tube. The flying object is equipped with the holding assembly. The X-ray detector is configured to detect the X-rays emitted by the X-ray tube. The processing circuitry is configured to control a flight of the flying object, and to control the flight of the flying object such that the X-ray tube is arranged on a predetermined position with respect to the X-ray detector.Type: ApplicationFiled: August 26, 2021Publication date: March 3, 2022Applicant: CANON MEDICAL SYSTEMS CORPORATIONInventors: Yoshimasa KOBAYASHI, Haruki IWAI, Toshikatsu OOHASHI, Masato AKIMOTO, Takehito TOMARU, Takehiro FUKUZAKI
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Publication number: 20200390408Abstract: According to one embodiment, an X-ray detection unit for a wheelchair includes a container and an attachment portion coupled with the container. The container is configured to contain a flat X-ray detector. The attachment portion is configured to be detachably mounted to a part of the wheelchair in which a subject is seated, so that a detection plane of the X-ray detector in the container faces the subject.Type: ApplicationFiled: June 2, 2020Publication date: December 17, 2020Applicant: Canon Medical Systems CorporationInventors: Takehiro FUKUZAKI, Masaharu Soya
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Patent number: 8415359Abstract: The present invention relates to a compound or a pharmacologically acceptable salt thereof having superior glucokinase activating activity, and is a compound represented by general formula (I), or pharmacologically acceptable salt thereof: [wherein, A represents, for example, an oxygen atom or sulfur atom, R1 represents, for example, a C1-C6 alkyl group, a C1-C6 alkoxy group or a C1-C6 halogenated alkyl group, A and R1 together with the carbon atom bonded thereto form a heterocyclic group that may be substituted with 1 to 3 group(s) independently selected from Substituent Group ?, R2 represents a phenyl group that may be substituted with 1 to 5 group(s) independently selected from Substituent Group ? or a heterocyclic group that may be substituted with 1 to 3 group(s) independently selected from Substituent Group ?, R3 represents a hydroxy group or a C1-C6 alkoxy group, and Substituent Group ? consists of, for example, a halogen atom, a C1-C6 alkyl group, a C1-C6 alkyl group substituted with 1 or 2 hydType: GrantFiled: August 5, 2011Date of Patent: April 9, 2013Assignee: Daiichi Sankyo Company, LimitedInventors: Akihiro Furukawa, Takehiro Fukuzaki, Yukari Onishi, Hideki Kobayashi, Takeshi Honda, Yumi Matsui, Masahiro Konishi, Kenjiro Ueda, Tetsuyoshi Matsufuji
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Patent number: 8235934Abstract: The object of the invention is to provide a functional thin tube device in which a pump and a liquid drawing device are constituted to be not separate without a sophisticated channel design and to correspond to various applications. A functional thin tube device includes a hollow tubular body, a plurality of vibrating ring bodies mounted as being kept in contact with the tubular body spaced an interval along an axial direction on an outer circumference of the tubular body, and an energy supply means of energy for vibrating the vibrating ring bodies. The energy supply means is constituted to supply energy such that the displacement caused by vibrations is mutually different among the vibrating ring bodies.Type: GrantFiled: February 20, 2008Date of Patent: August 7, 2012Assignee: Tokai University Educational SystemInventors: Kazuyoshi Tsuchiya, Akifumi Morishima, Yasutomo Uetsuji, Takehiro Fukuzaki
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Publication number: 20120022075Abstract: The present invention relates to a compound or a pharmacologically acceptable salt thereof having superior glucokinase activating activity, and is a compound represented by general formula (I), or pharmacologically acceptable salt thereof: [wherein, A represents, for example, an oxygen atom or sulfur atom, R1 represents, for example, a C1-C6 alkyl group, a C1-C6 alkoxy group or a C1-C6 halogenated alkyl group, A and R1 together with the carbon atom bonded thereto form a heterocyclic group that may be substituted with 1 to 3 group(s) independently selected from Substituent Group ?, R2 represents a phenyl group that may be substituted with 1 to 5 group(s) independently selected from Substituent Group ? or a heterocyclic group that may be substituted with 1 to 3 group(s) independently selected from Substituent Group ?, R3 represents a hydroxy group or a C1-C6 alkoxy group, and Substituent Group ? consists of, for example, a halogen atom, a C1-C6 alkyl group, a C1-C6 alkyl group substituted with 1 or 2 hydType: ApplicationFiled: August 5, 2011Publication date: January 26, 2012Inventors: Akihiro FURUKAWA, Takehiro FUKUZAKI, Yukari ONISHI, Hideki KOBAYASHI, Takeshi HONDA, Yumi MATSUI, Masahiro KONISHI, Kenjiro UEDA, Tetsuyoshi MATSUFUJI
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Patent number: 8017610Abstract: The present invention relates to a compound or a pharmacologically acceptable salt thereof having superior glucokinase activating activity, and is a compound represented by general formula (I), or pharmacologically acceptable salt thereof: [wherein, A represents, for example, an oxygen atom or sulfur atom, R1 represents, for example, a C1-C6 alkyl group, a C1-C6 alkoxy group or a C1-C6 halogenated alkyl group, A and R1 together with the carbon atom bonded thereto form a heterocyclic group that may be substituted with 1 to 3 group(s) independently selected from Substituent Group ?, R2 represents a phenyl group that may be substituted with 1 to 5 group(s) independently selected from Substituent Group ? or a heterocyclic group that may be substituted with 1 to 3 group(s) independently selected from Substituent Group ?, R3 represents a hydroxy group or a C1-C6 alkoxy group, and Substituent Group ? consists of, for example, a halogen atom, a C1-C6 alkyl group, a C1-C6 alkyl group substituted with 1 or 2 hydType: GrantFiled: July 26, 2010Date of Patent: September 13, 2011Assignee: Daiichi Sankyo Company, LimitedInventors: Akihiro Furukawa, Takehiro Fukuzaki, Yukari Onishi, Hideki Kobayashi, Takeshi Honda, Yumi Matsui, Masahiro Konishi, Kenjiro Ueda, Tetsuyoshi Matsufuji
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Publication number: 20110003787Abstract: The present invention relates to a compound or a pharmacologically acceptable salt thereof having superior glucokinase activating activity, and is a compound represented by general formula (I), or pharmacologically acceptable salt thereof: [wherein, A represents, for example, an oxygen atom or sulfur atom, R1 represents, for example, a C1-C6 alkyl group, a C1-C6 alkoxy group or a C1-C6 halogenated alkyl group, A and R1 together with the carbon atom bonded thereto form a heterocyclic group that may be substituted with 1 to 3 group(s) independently selected from Substituent Group ?, R2 represents a phenyl group that may be substituted with 1 to 5 group(s) independently selected from Substituent Group ? or a heterocyclic group that may be substituted with 1 to 3 group(s) independently selected from Substituent Group ?, R3 represents a hydroxy group or a C1-C6 alkoxy group, and Substituent Group ? consists of, for example, a halogen atom, a C1-C6 alkyl group, a C1-C6 alkyl group substituted with 1 or 2 hydType: ApplicationFiled: July 26, 2010Publication date: January 6, 2011Inventors: Akihiro Furukawa, Takehiro Fukuzaki, Yukari Onishi, Hideki Kobayashi, Takeshi Honda, Yumi Matsui, Masahiro Konishi, Kenjiro Ueda, Tetsuyoshi Matsufuji
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Publication number: 20100094223Abstract: The object of the invention is to provide a functional thin tube device in which a pump and a liquid drawing device are constituted to be not separate without a sophisticated channel design and to correspond to various applications. A functional thin tube device includes a hollow tubular body, a plurality of vibrating ring bodies mounted as being kept in contact with the tubular body spaced an interval along an axial direction on an outer circumference of the tubular body, and an energy supply means of energy for vibrating the vibrating ring bodies. The energy supply means is constituted to supply energy such that the displacement caused by vibrations is mutually different among the vibrating ring bodies.Type: ApplicationFiled: February 20, 2008Publication date: April 15, 2010Applicant: TOKAI UNIVERSITY EDUCATIONAL SYSTEMInventors: Kazuyoshi Tsuchiya, Akifumi Morishima, Yasutomo Uetsuji, Takehiro Fukuzaki
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Publication number: 20090036492Abstract: The present invention relates to a novel cercosporamide derivative, a pharmacologically acceptable salt thereof or an ester thereof which has an excellent hypoglycemic effect and is useful as a therapeutic and/or prophylactic agent for diabetes.Type: ApplicationFiled: August 8, 2006Publication date: February 5, 2009Inventors: Akihiro Furukawa, Jun Ohsumi, Tsuyoshi Arita, Takehiro Fukuzaki, Kazushi Araki, Makoto Mori, Takayuki Momose, Takeshi Honda, Masanori Kuroha, Ryo Okuyama, Susumu Satoh