Patents by Inventor Takehiro Funamoto

Takehiro Funamoto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Glutamine synthetase reaction and method for quantifying ammonia utilizing the same
    Patent number: 11162123
    Abstract: A reagent for glutamine synthetase reaction comprising a chelating agent and glutamine synthetase, and a reagent for quantification of ammonia comprising a chelating agent, ATP, glutamic acid, glutamine synthetase, glucose, an oxidized NAD compound, ADP-dependent hexokinase, and glucose-6-phosphate dehydrogenase, are provided.
    Type: Grant
    Filed: August 8, 2018
    Date of Patent: November 2, 2021
    Assignee: ARKRAY, Inc.
    Inventors: Masaki Murakami, Takehiro Funamoto
  • Quantification method for ammonia, quantification reagent kit, test piece, and ammonia quantification device
    Patent number: 10731200
    Abstract: A method of quantifying ammonia, which method includes: performing a first reaction in which a test liquid containing ammonia is reacted with ATP and L-glutamic acid in the presence of glutamine synthetase to produce ADP; performing a second reaction in which the produced ADP is reacted with glucose in the presence of ADP-dependent hexokinase to produce glucose-6-phosphate; performing a third reaction in which the produced glucose-6-phosphate is reacted with an oxidized NAD compound in the presence of glucose-6-phosphate dehydrogenase to produce a reduced NAD compound; and quantifying the reduced NAD compound to quantify ammonia.
    Type: Grant
    Filed: October 19, 2017
    Date of Patent: August 4, 2020
    Assignee: ARKRAY, Inc.
    Inventors: Takehiro Funamoto, Masaki Murakami
  • Glutamine Synthetase Reaction and Method for Quantifying Ammonia Utilizing the Same
    Publication number: 20190048373
    Abstract: A reagent for glutamine synthetase reaction comprising a chelating agent and glutamine synthetase, and a reagent for quantification of ammonia comprising a chelating agent, ATP, glutamic acid, glutamine synthetase, glucose, an oxidized NAD compound, ADP-dependent hexokinase, and glucose-6-phosphate dehydrogenase, are provided.
    Type: Application
    Filed: August 8, 2018
    Publication date: February 14, 2019
    Applicant: ARKRAY, Inc.
    Inventors: Masaki Murakami, Takehiro Funamoto
  • Quantification Method for Ammonia, Quantification Reagent Kit, Test Piece, and Ammonia Quantification Device
    Publication number: 20180112250
    Abstract: A method of quantifying ammonia, which method includes: performing a first reaction in which a test liquid containing ammonia is reacted with ATP and L-glutamic acid in the presence of glutamine synthetase to produce ADP; performing a second reaction in which the produced ADP is reacted with glucose in the presence of ADP-dependent hexokinase to produce glucose-6-phosphate; performing a third reaction in which the produced glucose-6-phosphate is reacted with an oxidized NAD compound in the presence of glucose-6-phosphate dehydrogenase to produce a reduced NAD compound; and quantifying the reduced NAD compound to quantify ammonia.
    Type: Application
    Filed: October 19, 2017
    Publication date: April 26, 2018
    Applicant: ARKRAY, Inc.
    Inventors: Takehiro Funamoto, Masaki Murakami
  • Quantification Method for Ammonia, Quantification Reagent, Quantification Reagent Kit, Test Piece, and Ammonia Quantification Device
    Publication number: 20180037927
    Abstract: A method of quantifying ammonia, the method includes performing a first reaction in which a test liquid containing ammonia is reacted with adenosine triphosphate and L-glutamic acid in the presence of glutamine synthetase to produce phosphoric acid, performing a second reaction in which the produced phosphoric acid is reacted with pyruvic acid in the presence of pyruvate oxidase, and measuring a component consumed or produced by the second reaction, to quantify ammonia, wherein a reaction to produce adenosine triphosphate from adenosine diphosphate mediated by pyruvate kinase is not carried out.
    Type: Application
    Filed: August 2, 2017
    Publication date: February 8, 2018
    Applicant: ARKRAY, Inc.
    Inventors: Koji Katsuki, Takehiro Funamoto, Masaki Murakami