Patents by Inventor Takehiro Hirano

Takehiro Hirano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Apoptosis signal-regulating kinase 1 inhibitors
    Patent number: 8921358
    Abstract: The present invention relates to apoptosis signal-regulating kinase 1 (“ASK1”) inhibiting compounds of the formula wherein the variables are as defined herein. The invention also relates to pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.
    Type: Grant
    Filed: March 28, 2013
    Date of Patent: December 30, 2014
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Edcon Chang, Matthew H. McNeill, Tracy Duong, Angie Vassar, Takehiro Hirano, Yoshito Terao
  • Substituted N-(pyrazolo[1,5-a]pyrimidin-5-yl)amides as inhibitors of apoptosis signal-regulating kinase 1
    Patent number: 8461163
    Abstract: The present invention relates to apoptosis signal-regulating kinase 1 (“ASK1”) . inhibiting compounds of the formula wherein the variables are as defined herein. The invention also relates to pharmaceutical compositions, kits and articles of manufacture comprising such compounds, to methods and intermediates useful for making the compounds, and to methods of using the compounds.
    Type: Grant
    Filed: March 30, 2009
    Date of Patent: June 11, 2013
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Edcon Chang, Tracy Duong, Takehiro Hirano, Matthew H. McNiell, Yoshito Terao, Angie Vassar
  • APOPTOSIS SIGNAL-REGULATING KINASE 1 INHIBITORS
    Publication number: 20110077235
    Abstract: The present invention relates to apoptosis signal-regulating kinase 1 (“ASK1”) inhibiting compounds of the formula (I); wherein the variables are as defined herein. The invention also relates to pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.
    Type: Application
    Filed: March 30, 2009
    Publication date: March 31, 2011
    Inventors: Edcon Chang, Tracy Duong, Takehiro Hirano, Matthew H. McNiell, Yoshito Terao, Angie Vassar
  • GSK-3BETA INHIBITOR
    Publication number: 20110039893
    Abstract: For the purpose of providing a GSK-3? inhibitor containing a 2-aminopyridine compound or a salt thereof or a prodrug thereof useful as an agent for the prophylaxis or treatment of a GSK-3?-related pathology or disease, the present invention provides a GSK-3? inhibitor containing a compound represented by the formula (IA): wherein each symbol is as defined in the specification. or a salt thereof or a prodrug thereof.
    Type: Application
    Filed: October 10, 2007
    Publication date: February 17, 2011
    Inventors: Masakuni Kori, Hideyuki Oki, Tetsuya Tsukamoto, Masashi Takahashi, Masaki Setoh, Takehiro Hirano
  • Semiconductor wafer having discharge structure to substrate
    Patent number: 6847096
    Abstract: To prevent an abnormal discharge phenomenon from occurring due to charge build up on conductive layer region that has a large surface area and that is a region other than the region where a semiconductor device is formed on a semiconductor substrate, the semiconductor substrate structure being made to have an electrical connection between the conductive layer region having a large surface area and the semiconductor substrate.
    Type: Grant
    Filed: November 4, 2002
    Date of Patent: January 25, 2005
    Assignee: Oki Electric Industry Co., Ltd.
    Inventors: Tetsuro Yanai, Hiroaki Kumagai, Takehiro Hirano
  • Semiconductor substrate structure and a semiconductor device
    Publication number: 20030181064
    Abstract: To prevent an abnormal discharge phenomenon on from occurring due to charge build up on a conductive layer region having a large surface area other than the region where a semiconductor device is formed on a semiconductor substrate. The semiconductor substrate structure is made to have an electrical connection between the conductive layer region having a large surface area and the semiconductor substrate.
    Type: Application
    Filed: November 4, 2002
    Publication date: September 25, 2003
    Inventors: Tetsuro Yanai, Hiroaki Kumagai, Takehiro Hirano