Abstract: An air-conditioning apparatus is an air-conditioning apparatus, for an air-conditioning target space in which a rack including a device as a heat-producing object is provided and which is separated by the rack into a cold space and a hot space, that makes return air from the hot space flow in so as to cool the return air and supplies an arbitrary air volume of the supplied air which is obtained by cooling the return air to the cold space by using a supply fan. The air-conditioning apparatus includes a processor. The processor executes a process including conducting control so that a temperature of the supplied air is equal to a prescribed value that is set in advance, and adjusting an air volume of the supplied air by controlling the supply fan so that a temperature of the return air is equal to a target value that is set in advance.

Abstract: An air-conditioning apparatus is an air-conditioning apparatus, for an air-conditioning target space in which a rack including a device as a heat-producing object is provided and which is separated by the rack into a cold space and a hot space, that makes return air from the hot space flow in so as to cool the return air and supplies an arbitrary air volume of the supplied air which is obtained by cooling the return air to the cold space by using a supply fan. The air-conditioning apparatus includes a processor. The processor executes a process including conducting control so that a temperature of the supplied air is equal to a prescribed value that is set in advance, and adjusting an air volume of the supplied air by controlling the supply fan so that a temperature of the return air is equal to a target value that is set in advance.

Abstract: A treatment device such as a biliary stent, capable of effectively and continuously inhibiting biofilm formation, and a biofilm formation inhibitor suitable for coating on the treatment device by killing all bacteria including E. coli and by suppressing the growth of these bacteria, are provided. A biofilm formation inhibitor having an effective amount of catechin for inhibiting biofilm formation and a carrier that is suitable for adhesion of said catechin to a treatment device to be placed in the living body, are provided.

Abstract: A medical adhesive comprises a hydrophilic urethane prepolymer (UP) obtained by reacting a fluorine-containing nonaromatic polyisocyanate component (A) and a polyol component (B) having a hydrophilic polyol (B1), and a phenolic radical scavenger (PRS). The content of (PRS) is preferably 0.01 to 3% by weight based on the weight of (UP). The content of oxyethylene groups in (B) is preferably 30 to 100% by weight based on the weight of the oxyalkylene groups in (B). Preferably, (B) is a mixture of a random copolymer obtained by addition of ethylene oxide and propylene oxide to diols and polypropylene glycol. The content of isocyanate groups in the medical adhesive is 1 to 10% by weight based on the weight of (UP). The medical adhesive is suitable for bonding body tissues, such as lung, artery and heart in particular.

Abstract: A treatment device such as a biliary stent, capable of effectively and continuously inhibiting biofilm formation, and a biofilm formation inhibitor suitable for coating on the treatment device by killing all bacteria including E. coli and by suppressing the growth of these bacteria, are provided. A biofilm formation inhibitor having an effective amount of catechin for inhibiting biofilm formation and a carrier that is suitable for adhesion of said catechin to a treatment device to be placed in the living body, are provided.

Abstract: A treatment device such as a biliary stent, capable of effectively and continuously inhibiting biofilm formation, and a biofilm formation inhibitor suitable for coating on the treatment device by killing all bacteria including E. coli and by suppressing the growth of these bacteria, are provided. A biofilm formation inhibitor having an effective amount of catechin for inhibiting biofilm formation and a carrier that is suitable for adhesion of said catechin to a treatment device to be placed in the living body, are provided.

Abstract: The present invention has its object to provide a medical adhesive excellent in safety, reactivity (curing rate) and duration of adhesive strength. A medical adhesive of the present invention comprises a hydrophilic urethane prepolymer (UP) obtained by reacting a fluorine-containing nonaromatic polyisocyanate component (A) and a polyol component (B) having a hydrophilic polyol (B1) as the essential component, and a phenolic radical scavenger (PRS). The content of (PRS) is preferably 0.01 to 3% by weight based on the weight of (UP). The content of oxyethylene groups in (B) is preferably 30 to 100% by weight based on the weight of the oxyalkylene groups in (B). Preferably, (B) is a mixture of a random copolymer obtained by addition of ethylene oxide and propylene oxide to diols and polypropylene glycol. The content of isocyanate groups in the medical adhesive is 1 to 10% by weight based on the weight of (UP).

Abstract: The present invention includes photocurable, liquid polymers incorporating coumarin ester endgroups into their molecular structure, which polymers are crosslinked upon irradiation with ultraviolet light by photochemically allowed [2+2] cycloaddition reactions among the chain ends, and which crosslinked polymers are useful in the preparation of medical devices, tissue engineering scaffolds, drug delivery systems and, in particular, in vivo preparation of implants in an open surgical procedure or laproscopically.

Abstract: The present invention provides a cell-containing preparation comprising cells containing a DNA having a base sequence represented by SEQ ID NO:1 or 2, or a DNA hybridizable with a DNA having a base sequence represented by SEQ ID NO:1 or 2 under stringent conditions, and a fibrous protein. The cell-containing preparation of the present invention makes it possible to more efficiently supply NK4 having an inhibitory action against the growth or metastasis of cancers to cancer cells.

Abstract: The present invention includes photocurable, liquid polymers incorporating coumarin ester endgroups into their molecular structure, which polymers are crosslinked upon irradiation with ultraviolet light by photochemically allowed [2+2] cycloaddition reactions among the chain ends, and which crosslinked polymers are useful in the preparation of medical devices, tissue engineering scaffolds, drug delivery systems and, in particular, in vivo preparation of implants in an open surgical procedure or laproscopically.

Abstract: The present invention includes photocurable, liquid polymers incorporating coumarin ester endgroups into their molecular structure, which polymers are crosslinked upon irradiation with ultraviolet light by photochemically allowed [2+2] cycloaddition reactions among the chain ends, and which crosslinked polymers are useful in the preparation of medical devices, tissue engineering scaffolds, drug delivery systems and, in particular, in vivo preparation of implants in an open surgical procedure or laproscopically.

Abstract: The object of the present invention is to provide a polymer best suited for use as a medical adhesive excellent in wet adhesion strength (water-resistant adhesive strength). In the present invention, a polymer capable of forming a cured film and useful as a medical adhesive, which has a viscosity at 37° C. of 0.5 to 2,000 Pa·s and shows a saturated water absorption of 0.2 to 5 ml/g, is used. The above-mentioned polymer preferably shows an initial water absorption rate of 0.01 to 0.5 ml/g·min, the wet elongation percentage of the cured film is preferably 100 to 1,500%, and the wet 100% modulus of the cured film is preferably 0.01 to 10 MPa. Additionally, it is preferable that the above-mentioned polymer contains oxyethylene groups and in which the oxyethylene group content is 30 to 100% by weight based on the weight of the polymer.

Abstract: The present invention includes photocurable, liquid polymers incorporating coumarin ester endgroups into their molecular structure, which polymers are crosslinked upon irradiation with ultraviolet light by photochemically allowed [2+2] cycloaddition reactions among the chain ends, and which crosslinked polymers are useful in the preparation of medical devices, tissue engineering scaffolds, drug delivery systems and, in particular, in vivo preparation of implants in an open surgical procedure or laproscopically.

Abstract: The present invention includes photocurable, liquid polymers incorporating coumarin ester endgroups into their molecular structure, which polymers are crosslinked upon irradiation with ultraviolet light by photochemically allowed [2+2] cycloaddition reactions among the chain ends, and which crosslinked polymers are useful in the preparation of medical devices, tissue engineering scaffolds, drug delivery systems and, in particular, in vivo preparation of implants in an open surgical procedure or laproscopically.

Abstract: The present invention includes photocurable, liquid polymers incorporating coumarin ester endgroups into their molecular structure, which polymers are crosslinked upon irradiation with ultraviolet light by photochemically allowed [2+2] cycloaddition reactions among the chain ends, and which crosslinked polymers are useful in the preparation of medical devices, tissue engineering scaffolds, drug delivery systems and, in particular, in vivo preparation of implants in an open surgical procedure or laproscopically.

Abstract: The present invention includes photocurable, liquid polymers incorporating coumarin ester endgroups into their molecular structure, which polymers are crosslinked upon irradiation with ultraviolet light by photochemically allowed [2+2] cycloaddition reactions among the chain ends, and which crosslinked polymers are useful in the preparation of medical devices, tissue engineering scaffolds, drug delivery systems and, in particular, in vivo preparation of implants in an open surgical procedure or laproscopically.

Abstract: In order to provide an adhesive to adhere to the tissue of organisms a buffered solution containing a protein macromer having a vinylated protein, a polysaccharide macromer having a vinylated polysaccharide, or the both by mixture, along with a photo-reactive compound which generates radicals by irradiation is prepared. The solution is cured into a gel state by irradiation, adheres to and is fixed on the tissue surface.

Abstract: The present invention provides semi-spherical materials to be worn on the eyeball, such as contact lenses for visual acuity correction or medical treatment use, cornea protecting materials, controlled drug release contact lenses and the like, which comprise, as a main component, a glycosaminoglycan existing in the living body as an extracellular matrix component of connective tissues and satisfy various requirements such as dimentional stability, transparency, surface water wettability, tissue compatibility, oxygen permeability and the like. In other words, the material to be worn on the eyeball has a shape of semi-spherical surface compatible in shape with the mammalian eyeball and has biological and surface-physical compatibilities with ophthalmic tissues and comprises, as a main component, a substantially transparent photocured crosslinked-glycosaminoglycan obtained by allowing photoreactive groups covalently bonded to a glycosaminoglycan to crosslink mutually by photoirradiation.

Abstract: A substrate for controlling the growth direction of serve fibers charcterized in that a nerve cell adhesive substance is fixed in the form of a desired pattern and a process for preparing the substrate, a method for controlling the growth direction of nerve fibers and a neuronal network.According to this invention, precise control of nerve fibers' growth direction is achieved.

Abstract: An infusion catheter having a catheter shaft with a distal end, an inflatable and contractible balloon provided adjacent the distal end but spaced therefrom, a blood passage with two openings for passing blood through the balloon, and first and second lumens. The first lumen communicating with the balloon to inflate and contract the balloon, and the second lumen including a medicine discharge port located between the balloon and one opening of the blood passage to supply medicine to a lesion part of a blood vessel.